The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei，Yunnan Province

Siwei YANG; Yan LI; Xia XIAO; Xiaoxiao SONG; Lin SUN; Rui MA

doi:10.12259/j.issn.2095-610X.S20241108

Volume 45 Issue 11

Nov. 2024

Turn off MathJax

Article Contents

Article Navigation > Journal of Kunming Medical University > 2024 > 45(11): 52-58

Siwei YANG, Yan LI, Xia XIAO, Xiaoxiao SONG, Lin SUN, Rui MA. The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei，Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(11): 52-58. doi: 10.12259/j.issn.2095-610X.S20241108

Citation:

Siwei YANG, Yan LI, Xia XIAO, Xiaoxiao SONG, Lin SUN, Rui MA. The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei，Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(11): 52-58. doi: 10.12259/j.issn.2095-610X.S20241108

Citation:

Siwei YANG, Yan LI, Xia XIAO, Xiaoxiao SONG, Lin SUN, Rui MA. The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei，Yunnan Province[J]. Journal of Kunming Medical University, 2024, 45(11): 52-58. doi: 10.12259/j.issn.2095-610X.S20241108

PDF( 604 KB)

The Analysis of Exposure and Influencing Factors of Pyrethroid Pesticides in Rural Women during Different Pregnancy Stages in Xuanwei，Yunnan Province

doi: 10.12259/j.issn.2095-610X.S20241108

1.
Dept. of Academic Affairs，Kunming Medical University
2.
School of Public Health，Kunming Medical University，Kunming Yunnan 650500
3.
School of Public Health and Health Management，Qujing Medical College，Qujing Yunnan 655000，China

Received Date: 2024-07-22
Available Online: 2024-11-09
Publish Date: 2024-11-25

Abstract

Abstract

Objective The purpose of the study is to understand the exposure of rural women to pyrethroid pesticides during each pregnancy stage. Methods From December 2014 to December 2016, 216 pregnant and postpartum women with the average age between 24.81±5.256 years old were recruited from 2 townships in Xuanwei rural area. Results In this study, the majority of pregnant women were still engaged in farming during pregnancy and self-reported no active exposure to pesticides during pregnancy. The self-reporting exposure rates among the three trimesters were no more than 1.4%. However, Laboratory testing found that the exposure rates of pyrethroid pesticides among the three trimester of pregnancy were exceed 90.0%, and the total of 67.1% of women exposed to pyrethroid pesticides in every trimester of gestation. Women exposure rates of pyrethroid by laboratory detection were significantly higher than those by questionnaire. In the first, the second and the third trimester, the medians of urine pyrethroid metabolites 3-PBA were 3.61 ng/ml、3.60 ng/ml、3.57 ng/ml, respectively, and the medians of urine cis/trans-DCCA, pyrethroid metabolites, distributed 49.10 ng/ml、45.45 ng/ml、47.45 ng/ml, respectively. The pregnancy exposure to pyrethroid pesticides was in the middle level of domestic research, but exceeded the level of most foreign reports. The result of women who exposed to pyrethroid pesticides in each trimester of gestation by Repeated Measures Define Factor（s） showed that address, education and family income had interaction with the three trimester pyrethroid metabolites amount （F _{gestation×address}=3.183, F _{gestation×education}=2.731, P<0.05）, and the amount by laboratory test in the first trimester and the second trimester were higher than that in the third trimester（LSD, P < 0.05）. Chi-square test indicated that there were no significant differences in the amounts of pyrethroid exposure among women age groups, between the minority and the majority, among different education levels, between on work and stopping work, between the two towns, across different family income and among the four seasons. Conclusion Rural pregnancy women are with low awareness of pesticide in Xuan wei. The vast majority of pregnancy women are exposed to pyrethroid pesticides in varying degrees and in the middle level of domestic research. Pyrethroid exposure in the third trimester is likely less serious than the other trimesters. The address, education and family income affect the pyrethroid exposure level. Therefore, it is necessary to strengthen health education and improve the health consciousness of pregnant women to reduce pyrethroids pesticides exposure as much as possible in rural areas.
- Pregnancy,
- Pyrethroid pesticides,
- Exposure,
- Rural area

FullText(HTML)

References(12)

References

[1]	Ding G,Shi R,Gao Y,et al. Pyrethroid pesticide exposure and risk of childhood acute lymphocytic leukemia in Shanghai[J]. Environ Sci Technol,2012,46(24):13480-13487. doi: 10.1021/es303362a
[2]	任方方,王金斌,张倩倩,等. 氰基类拟除虫菊酯类农药检测研究进展[J]. 现代农业科技,2014,17(42):150-152. doi: 10.3969/j.issn.1007-5739.2014.18.096
[3]	Du G,Shen O,Sun H,et al. Assessing hormone receptor activities of pyrethroid insecticides and their metabolites in reporter gene assays[J]. Toxicol Sci,2010,116(1):58-66. doi: 10.1093/toxsci/kfq120
[4]	Erkmen B. Spermiotoxicity and embryotoxicity of permethrin in the sea urchin Paracentrotus lividus[J]. Bull Environ Contam Toxicol,2015,94(4):419-424.
[5]	Berkowitz G S,Wetmur J G,Birman-Deych E,et al. In utero pesticide exposure,maternal paraoxonase activity,and head circumference[J]. Environ Health Perspect,2004,112(3):388-391. doi: 10.1289/ehp.6414
[6]	Kennedy D,Hurst V,Konradsdottir E,et al. Pregnancy outcome following exposure to permethrin and use of teratogen information[J]. Am J Perinatol,2005,22(2):87-90. doi: 10.1055/s-2005-837736
[7]	Ostrea E M Jr,Reyes A,Villanueva-Uy E,et al. Fetal exposure to propoxur and abnormal child neurodevelopment at 2 years of age[J]. Neurotoxicology,2012,33(4):669-675. doi: 10.1016/j.neuro.2011.11.006
[8]	Mytton O T,McGready R,Lee S J,et al. Safety of benzyl benzoate lotion and permethrin in pregnancy: A retrospective matched cohort study[J]. Biog,2007,114(5):582-587.
[9]	Xue Z,Li X,Su Q,et al. Effect of synthetic pyrethroid pesticide exposure during pregnancy on the growth and development of infants[J]. Asia Pac J Public Health,2013,25(4 Suppl): 72S-79S.
[10]	齐小娟,郑明岚,邬春华,等. 宫内拟除虫菊酯类农药暴露对1岁幼儿神经发育的影响[J]. 卫生研究,2011,40(6):693-697.
[11]	Roberts J R,Karr C J. Pesticide exposure in children[J]. Pediatrics,2012,130(6):e1765-e1788. doi: 10.1542/peds.2012-2758
[12]	Ding G D,Cui C,Chen L M,et al. Prenatal exposure to pyrethroid insecticides and birth outcomes in rural northern China,[J]. Journal of Exposure Science and Enviromental Epidemiology,2015 ,25(3): 264-270.

Relative Articles(20)

Relative Articles

[1]	You HUANG, Guohui LI, Duli LIU, Zizi YU, Mei ZUO, Qin LI, Bo LYU, Le CAI. Prevalence of Hypertension and Its Relationship with Clustering of Risk Factors of Cardiovascular Diseases in The Elderly of Han Majority and Ha Ni Ethnic Minority in Rural District of Mojiang County of Yunnan Province. Journal of Kunming Medical University, 2024, 45(9): 42-48. doi: 10.12259/j.issn.2095-610X.S20240907
[2]	Qichuan HU, Hechuan ZHANG, Lichun JIANG, Yajing ZHANG, Fujing FENG, Ximeng ZHAO, Yunxian WANG. Mental Health Status and Its Influencing Factors Among Elderly Hypertension Patients from Rural Areas of Chuxiong and Honghe Prefecture in Yunnan. Journal of Kunming Medical University, 2024, 45(3): 92-98. doi: 10.12259/j.issn.2095-610X.S20240314
[3]	Zhiye QI, Ying CHEN, Yan LI. Research Progress on Immunotoxicology of Pyrethroid Pesticides Exposures. Journal of Kunming Medical University, 2024, 45(8): 154-160. doi: 10.12259/j.issn.2095-610X.S20240822
[4]	Hui DING, Lan YAO. Oral Health Status Associated with Quality of Life among the Elderly over 60 Years Old in the Rural Areas of Yunnan Province. Journal of Kunming Medical University, 2021, 42(5): 59-63. doi: 10.12259/j.issn.2095-610X.S20210511
[5]	Lian-ju HE, Chun-mei ZUO, Lan LIU, Wen-long CUI, Jin-bo LI, Yi MO, Lu-ming FAN, Le CAI. Analysis of Trend in Prevalence of Hypertension and Its Relationship with Different Obesity Indices among Rural Adults in Fumin County of Yunnan Province. Journal of Kunming Medical University, 2021, 42(10): 38-44. doi: 10.12259/j.issn.2095-610X.S20211008
[6]	Hui DING, Lan YAO. Periodontal Status and Its Influencing Factors in Rural Population aged 65-74 in Yunnan Province. Journal of Kunming Medical University, 2021, 42(4): 38-43. doi: 10.12259/j.issn.2095-610X.S20210407
[7]	Bo TIAN, Jun LIU, Chong-xi LI, Rong HE, Shan-qun GU, Wei-bo WANG. Effect of HIV Post-exposure Prophylaxis in Kunming City in 2019. Journal of Kunming Medical University, 2021, 42(7): 126-129. doi: 10.12259/j.issn.2095-610X.S20210721
[8]	Ma Rui , Li Yan . Research Progress of Exposure to Pyrethroid Pesticides Impact on Reproductive System of Human and Physical Development of Infants. Journal of Kunming Medical University, 2019, 40(03): 126-130.
[9]	Wang Yi Jie , Tang Kun , He Chen , Yang Lei , Xu Wang Bin . . Journal of Kunming Medical University, 2019, 40(06): 98-102.
[10]	Zhao Guang Hong , Cui Wen Long , Wu Hui Xin , Zhao Ling , Cai Le . Status and Influencing Factors of Public Health Services Utilization among Rural Patients with Severe Mental Illness in Yunnan Province. Journal of Kunming Medical University, 2018, 39(01): 35-38.
[11]	Sun Lin , Xiao Xia , Li Yan , Yang Si Wei , Xu Qing Hua , Ma Rui , Wu Jie , Zhang Chao , Guo Guang Ping . Pyrethroid Exposure and Related Factors among Pregnant Women in the First Trimester in Rural Yunnan Province, China. Journal of Kunming Medical University, 2018, 39(06): 39-43.
[12]	He Jian Hui . The Distribution of Body Weight Related Index and Relationship with Cardiovascular Diseases in Rural Residents of Yunnan Province. Journal of Kunming Medical University,
[13]	Zheng Xu . . Journal of Kunming Medical University,
[14]	Zhu Yong Fen . . Journal of Kunming Medical University,
[15]	Sun Heng . . Journal of Kunming Medical University,
[16]	Chen Wei Wen . Clinical Study of Subclinical Hypothyroidism during Pregnancy. Journal of Kunming Medical University,
[17]	Zhu Ying . . Journal of Kunming Medical University,
[18]	Shi Bao Tang . . Journal of Kunming Medical University,
[19]	Zhang Hong Yun . Clinical Analysis of 26 Cases of Ovarian Pregnancy. Journal of Kunming Medical University,
[20]	. . Journal of Kunming Medical University,