The Influence of C-type Natriuretic Peptide Gene induced by Polyethylenimine on the Intima Hyperplasia at Injured Vessels after Iliac Aortic Sac Plasty in Rabbit Model[J]. Journal of Kunming Medical University, 2011, 32(08).
Citation: The Influence of C-type Natriuretic Peptide Gene induced by Polyethylenimine on the Intima Hyperplasia at Injured Vessels after Iliac Aortic Sac Plasty in Rabbit Model[J]. Journal of Kunming Medical University, 2011, 32(08).

The Influence of C-type Natriuretic Peptide Gene induced by Polyethylenimine on the Intima Hyperplasia at Injured Vessels after Iliac Aortic Sac Plasty in Rabbit Model

  • Objective To discuss the potential role of C-type natriuretic peptide(CNP)in vascular restenosis prevention after aortic sac plasty by observating the influence of CNP on the intima hyperplasia.Methods Reconstructed plasmid pcDNA3.1/hCNP was transfected with polyethylenimine(PEI)by catheter method in iliac artery of rabbit model of atherosclerosis.The expression of pcDNA3.1/hCNP was confirmed with RT-PCR,immunohistochemistry and Western blot.The hyperplasia of intima was detected with elastic fibers stainin...
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