The Relationship between the Inflammation of Mucosa and the Curative Effect of Eosinophilic Chronic Sinusitis

Wang Cheng Gang; Wu Hai Ying

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Wang Cheng Gang , Wu Hai Ying . The Relationship between the Inflammation of Mucosa and the Curative Effect of Eosinophilic Chronic Sinusitis[J]. Journal of Kunming Medical University, 2018, 39(04): 66-69.

Citation:

Wang Cheng Gang , Wu Hai Ying . The Relationship between the Inflammation of Mucosa and the Curative Effect of Eosinophilic Chronic Sinusitis[J]. Journal of Kunming Medical University, 2018, 39(04): 66-69.

Citation:

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The Relationship between the Inflammation of Mucosa and the Curative Effect of Eosinophilic Chronic Sinusitis

Wang Cheng Gang ¹,
Wu Hai Ying ²

Funds:

基金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目 (2017FE467);

Received Date: 2017-10-24

Abstract

Abstract

Objective To explore the relationship between the mucosal inflammation and the surgical efficacy of patients with eosinophilic chronic sinusitis. Me thods From September 2014 to September 2017, 30 patients with chronic eosinophils sinusitis were selected in our hospital. We colored the sinus tissue paraffin specimens by HE staining, calculated the number of inflammatory cells by microscope observation and the number of eosinophils contained, determined the eosinophil infiltration degree, evaluated the effect of surgical treatment, and analyzed the eosinophil infiltration degree and the relationship between the clinical classification.Re s ults The infiltration degree of the mucosa related eosinophilic granulocytes was significantly lower (χ2=7.6876, P =0.0055) after1-2 weeks after surgery for patients with chronic sinusitis. The degree of infiltration of the mucosa related eosinophilic granulocytes at 4 weeks and 6 weeks after surgery was 3 and 4. There was no significant difference before surgery (χ2=0.3267, P=0.5676) . The degree of infiltration of the mucosa related eosinophils in the 10-12 weeks after surgery was significantly lower than that in grade 3 and 4 (χ2=13.4842, P=0.0002) . In 30 patients with chronic sinusitis, the treatment efficiency of the mucosa associated eosinophilic granulocytic infiltration level was level 3 and level 4 (χ2= 23.0990, 23.0990, P= 0.0000, 0.0000) . The treatment efficiency of the lesion of the mucosa of patients with chronic sinusitis was level 2 and the level of infiltration was 3 and 4 (χ2=12.2817, 12.2817, P =0.0004, 0.0004) . In the clinical fractal type 1, the degree of infiltration level 1 and 2 was distributed, and the degree of infiltration level 3 and 4 was absent; In the clinical fractal type 2, the degree of infiltration level 1 was mostly observed and the degree of infiltration level 2, 3 and 4 was distributed; In the clinical fractal type 3, the degree of infiltration level 1 was mostly observed and the degree of infiltration level 2, 3 and 4 was distributed. The comparison between infiltration degree level 1 and level 2 of the total clinical classification and the type 2 percentage infiltration degree level 3 and level 4 was not significant (χ2=0.3801, 0.3801 and 0.3801, 0.3801, P=0.5375, 0.5375, 0.5375, 0.5375) . Conclusion There is a certain relationship between the mucosal inflammation and the curative effect of eosinophilic chronic sinusitis.
- Eosinophil,
- Chronic sinusitis,
- Mucosal inflammation,
- Curative effect,
- Relationship

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