Clinical Analysis of the Spectrum of Upper Gastrointestinal Diseases in 424 Cases of Children in A Tertiary Hospital in Kunming

Yanjuan CHEN; Wanrong LUO; Ruixue MA; Yilin DAI; Guixian LI; Yunfen TIAN

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Yanjuan CHEN, Wanrong LUO, Ruixue MA, Yilin DAI, Guixian LI, Yunfen TIAN. Clinical Analysis of the Spectrum of Upper Gastrointestinal Diseases in 424 Cases of Children in A Tertiary Hospital in Kunming[J]. Journal of Kunming Medical University.

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Clinical Analysis of the Spectrum of Upper Gastrointestinal Diseases in 424 Cases of Children in A Tertiary Hospital in Kunming

Dept. of Pediatrics，The Affiliated Hospital of Kunming University of Science and Technology/The 1st People’s Hospital of Yunnan Province，Kunming Yunnan 650032，China

Received Date: 2024-08-05
Available Online: 2024-11-23

Abstract

Abstract

Objective To investigate the clinical features of the spectrum of upper gastrointestinal diseases in children and to provide assistance in the prevention, diagnosis and treatment of upper gastrointestinal diseases in children. Methods Clinical data of 424 children aged 2 months to 14 years who were hospitalised for gastroscopy in the paediatrics department of the First People's Hospital of Yunnan Province from January 2018 to June 2023 were collected, and retrospective analyses were performed for the children's clinical presentation, gastroscopy results, and HP infections. Results The symptoms of vomiting and diarrhea in infants were significantly different from those in preschool and school age groups （P < 0.05）. The positive rate of lesions under gastroscopy was 96.46%. The main diseases found were non-atrophic gastritis （222 cases）, bile reflux gastritis （42 cases）, non-atrophic gastritis with erosion （30 cases）, duodenitis （25 cases）, reflux esophagitis （15 cases） and others （75 cases）. Helicobacter pylori （HP） was detected in 300 of the 424 cases, and 105 cases were HP positive, with a detection rate of 35.00%. Conclusion The symptoms of upper gastrointestinal disorders in children are diverse. Abdominal pain is the main symptom of upper gastrointestinal disorders in school-age and preschool children; vomiting and diarrhoea are the main symptoms of upper gastrointestinal disorders in infants and toddlers. Inflammation is the most common form of upper gastrointestinal disease in children, and there is no gender difference in HP infection, but there is an age difference.
- Children,
- Gastroscopy,
- Upper gastrointestinal diseases,
- Helicobacter pylori

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References(23)

References

[1]	王静,李丹,林兵,等. 无痛电子胃镜和普通电子胃镜上消化道疾病检出率的分析[J]. 智慧健康,2022,8(23):66-69+74.
[2]	方之洪,刘春,周慧,等. 艾司奥美拉唑为主的四联疗法治疗幽门螺杆菌阳性儿童消化性溃疡的疗效分析[J]. 现代消化及介入诊疗,2018,23(06):753-755.
[3]	郁春,徐金梅,李清峰,等. 无痛电子消化内镜在儿童消化道疾病中的应用分析[J]. 基层医学论坛,2021,25(16):2253-2255.
[4]	Zhan Y,Liang S,Yang Z,et al. Efficacy and safety of subanesthetic doses of esketamine combined with propofol in painless gastrointestinal endoscopy: prospective,double-blind,randomized controlled trial[J]. BMC Gastroenterol,2022,22(1):391. doi: 10.1186/s12876-022-02467-8
[5]	吕贤茂,陈波,许瑞华. 急诊胃镜检查和治疗在急性上消化道出血疾病中的作用探讨[J]. 中国医药科学,2020,10(13):203-205.
[6]	王宝西. 儿童消化内镜发展的过去现在与将来[J]. 中国实用儿科杂志,2018,33(11):821-824.
[7]	徐龙. 无痛胃镜不良事件的分析及防治措施 [D];长春: 吉林大学,2018.
[8]	江米足,龚四堂. 中华医学会儿科学分会消化学组历史沿革与发展[J]. 中华儿科杂志,2015,53(4):248-251.
[9]	YanYing P,ShenLing L,XiaoHan P,et al. Incidence and risk factors associated with negative postoperative behavioral changes in children undergoing painless gastroscopy[J]. BMC Pediatr,2023,23(1):371. doi: 10.1186/s12887-023-04187-8
[10]	钟雪梅,许春娣. 中国儿童胃镜结肠镜检查规范操作专家共识[J]. 中国实用儿科杂志,2018,33(11):817-820.
[11]	中华医学会儿科学分会感染消化学组,陈洁. 小儿慢性胃炎、消化性溃疡胃镜诊断标准[J]. 中华儿科杂志,2003,12(03):33.
[12]	房静远,杜奕奇,刘文忠,等. 中国慢性胃炎共识意见(2017年,上海)[J]. 中华消化杂志,2017,37(11):721-738.
[13]	中华医学会儿科学分会消化学组,国家儿童医学中心消化专科联盟,中华儿科杂志编辑委员会. 中国儿童幽门螺杆菌感染诊治专家共识(2022)[J]. 中华儿科杂志,2023,61(07):580-587. doi: 10.3760/cma.j.cn112140-20220929-00849
[14]	潘火云. 328例儿童消化性溃疡单中心临床分析 [D];苏州: 苏州大学,2019.
[15]	马小龙,刘春霞,马金海. 幽门螺杆菌感染与儿童电子胃镜检查结果的临床分析[J]. 宁夏医学杂志,2023,45(4):332-334.
[16]	朱丹荣,盛伟松,薛娟,等. 199例儿童胃镜应用分析[J]. 中国处方药,2019,17(12):5-6.
[17]	郁春,徐金梅,李清峰,等. 无痛电子消化内镜在儿童消化道疾病中的应用分析[J]. 基层医学论坛,2021,25(16):2253-2255.
[18]	Adeniyi O F,Odeghe E A,Lawal M A,et al. Recurrent abdominal pain and upper gastrointestinal endoscopy findings in children and adolescents presenting at the Lagos University Teaching Hospital[J]. PLoS One,2019,14(5):e0216394.
[19]	Seo J H,Bortolin K,Jones N L. Review: Helicobacter pylori infection in children [J]. Helicobacter,2020,25 Suppl 1: e12742.
[20]	Yuan C,Adeloye D,Luk T T,et al. The global prevalence of and factors associated with Helicobacter pylori infection in children: a systematic review and meta-analysis[J]. Lancet Child Adolesc Health,2022,6(3):185-194. doi: 10.1016/S2352-4642(21)00400-4
[21]	李春霞,王学红,马臻棋. 青海地区家庭内成员幽门螺杆菌感染情况及危险因素分析[J]. 中华内科杂志,2024(01):41-45.
[22]	Hsieh H,Yang H B,Sheu B S,et al. Atrophic gastritis in Helicobacter pylori-infected children[J]. Helicobacter,2022,27(3):e12885. doi: 10.1111/hel.12885
[23]	朱丹荣,周莉,古丽米拉·霍加合买提,等. 新疆地区单中心儿童胃镜应用分析[J]. 新疆医学,2023,53(06):694-697.

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