2016 Vol. 37, No. 05

The Activation and Polarization of Microglia in Epileptic Rats Induced by Pilocarpine
Zhong Lian Mei
2016, 37(05)
Abstract(3752) PDF(361) Cited By (7)
Abstract:
[Abstract]Objective To explore the activition and polarization of microglia in the epileptic rats induced by lithium chloride-pilocarpine. Methods One hundred male SD rats were randomly divided into five groups: control group and different time point...
Association Study of TNF-α and ALCAM Polymorphisms with Chronic HCV Infection in Yunnan Han Population
Liu Cheng Xiu
2016, 37(05)
Abstract(3922) PDF(184)
Abstract:
[Abstract]Objective To discuss the association of allele polymorphisms SNP-rs1799724 (C>T) in the TNF-α and SNP-rs11559013(G>A) in the ALCAM with HCV chronic infection in Han population in Yunnan province. Methods 434 HCV chronic infectious patients ...
IL-27 Alleviates the Bleomycin-induced Pulmonary Fibrosis through Regulating TGF-β/Smad Signaling Pathway
Lei Wen
2016, 37(05)
Abstract(3250) PDF(243) Cited By (14)
Abstract:
[Abstract]Objective To explore whether IL-27 inhibited the pulmonary fibrosis through regulating the expression of TGF-β/Smad signaling pathway in the bleomycin-induced pulmonary fibrosis model. Methods Forty male C57/BL6 mice were randomly divided i...
The Distribution of Body Weight Related Index and Relationship with Cardiovascular Diseases in Rural Residents of Yunnan Province
He Jian Hui
2016, 37(05)
Abstract(3426) PDF(220) Cited By (4)
Abstract:
[Abstract]Objective The aim of this study was to investigate the distribution of body weight related index and to explore the relationship between weight related index and cardiovascular diseases in rural residents in Yunnan Province. Methods By rand...
Genetic Polymorphism of 20 Autosomal STR Loci in Yunnan Han Popolation
Hu Li Ping
2016, 37(05)
Abstract(2852) PDF(246) Cited By (13)
Abstract:
[Abstract]Objective To study the genetic polymorphism of 20 autosomal short tandem repeats (STR) loci in Yunnan Han population. Methods The 20 STR loci (D3S1358, D1S1656, D6S1043, D13S317, Penta E,D16S539,D18S51,D2S1338,CSF1PO,Penta D,TH01,vWA,D21S11...
Correlation of mTOR and VEGF Gene with Nephropathy in Diabetic Rats
Tao Wen Yu
2016, 37(05)
Abstract(2907) PDF(226) Cited By (3)
Abstract:
[Abstract]Objective The purpose of this study was to observe the correlation of mTOR and VEGF gene with nephropathy indicators in diabetic rats. Methods Forty-eight male Sprague-Dawley(SD)rats were divided into diabetes mellitus group (DM=28) and con...
Effect of SGK1 on the Protection of Ischemia Reperfusion Model Rats
Zhang Wei
2016, 37(05)
Abstract(2698) PDF(433)
Abstract:
[Abstract]Objective To seek the effect of SGK1 on the protection and prognosis of cerebral ischemia reperfusion. Methods Animal model of rats was used to construct them into experimental group(A)and control group(B). The impact of cerebral ischemia r...
Effect of Fragile Site WWOX Gene on Regulating Proliferation of Human Gallbladder Cancer Cells in Vitro
Wei Dong
2016, 37(05)
Abstract(3731) PDF(207) Cited By (3)
Abstract:
[Abstract]Objective To explore the effect and mechanism of fragile site WWOX gene on regulating proliferation of gallbladder cancer cells in vitro. Methods The pcDNA3.0 - WWOX recombinant plasmid which was previous successfully built was transfected ...
Anti-fibrotic Effect of Kudancao Tablets on Bleomycin-induced Pulmonary Fibrosis in Rats
Wang Ying Xia
2016, 37(05)
Abstract(2703) PDF(182) Cited By (11)
Abstract:
[Abstract]Objective To investigate the anti-fibrotic effect of Kudancao tablets on bleomycin-induced pulmonary fibrosis in rats . Methods Forty healthy adult SD rats(200±20g)were randomly divided into 4 groups: normal control group(without any treatm...
The Correlation of Polymorphisms of AT1R A1166C and AGT M235T Genes and Blood Biochemical Indicators with Essential Hypertension in the Male of Yi Nationality in Yunnan Province
Luo Lan
2016, 37(05)
Abstract(2251) PDF(210) Cited By (4)
Abstract:
[Abstract]Objective To investigate the correlation of the polymorphisms of angiotensin Ⅱ type 1 receptor (AT1R) gene A1166C and angiotensinogen(AGT)gene M235T and blood biochemical indicators with essential hypertension(EH)in the male of Yi nationali...
Anti-tumor Effects of Total Saponins Extract from the Aerial and Underground Parts of Paris polyphylla var. yunnanensis
Li Ju
2016, 37(05)
Abstract(2122) PDF(205) Cited By (23)
Abstract:
[Abstract]Objective To investigate the anti-tumor effects of total saponins, extracted from stems and leaves of Paris polyphylla var. yunnanensis. Methods Taking mouse stomach carcinoma MFC cell line, human mammary cancer cell line(MCF-7)and human ce...
Risk-Treatment Paradox in Acute Coronary Syndrome
Li Rui Jie
2016, 37(05)
Abstract(2986) PDF(434) Cited By (1)
Abstract:
[Abstract]Objective This study aimed to assess the adherence to guideline-recommended therapies according to risk stratification in the management of acute coronary syndrome(ACS). Methods We analyzed 1,001 consecutive patients admitted with ACS. Pati...
Analysis of Clinical Characteristics and Misdiagnosis of 178 Patients with Pulmonary Embolism
Shen Wen
2016, 37(05)
Abstract(3665) PDF(149) Cited By (14)
Abstract:
[Abstract]Objective The study aimed to analyze the clinical data of patients with pulmonary embolism and summarize the clinical characteristics of pulmonary embolism, in order to improve the correct diagnostic rate and the prognosis. Methods Data of ...
Comparison of Postoperative Efficacy between Cylindrical Abdominoperineal Resection by Laparoscopy and Traditional Abdominoperineal Resection
Zhang Hong Bin
2016, 37(05)
Abstract(3116) PDF(216) Cited By (3)
Abstract:
[Abstract]Objective To evaluate the efficacy between cylindrical abdominoperineal resection (CAPR) by laparoscopy and traditional abdominoperineal resection(APR). Methods A retrospectively analysis was done in the data of patients with low rectal can...
Detection of Four Infection Indicators in 20 Patients with Knee Infection after Operation
Wang Fu Ke
2016, 37(05)
Abstract(2926) PDF(394) Cited By (4)
Abstract:
[Abstract]Objective To investigate the detection results of WBC, CRP, ESR and GR% in patients with knee infection after operation. Methods The study was conducted from March 2012 to January 2015. Twenty patients were collected in the study. The value...
Different Prostheses in Artificial Hip Replacement for Osteoporotic Femoral Neck Fracture in Elderly Patients
Liang Da Wei
2016, 37(05)
Abstract(2196) PDF(190) Cited By (23)
Abstract:
[Abstract]Objective To evaluate the early effect and safety of artificial hip replacement for treating senile osteoporosis femoral neck fractures with different prostheses choice. Methods From January 2006 to April 2014, 387 patients with senile oste...
Analysis of Amino Acids and Acylcarnitines in the Blood of Patients First Diagnosed with Uremia Using Tandem Mass Spectrometry
Zeng Hui Juan
2016, 37(05)
Abstract(2609) PDF(199) Cited By (1)
Abstract:
[Abstract]Objective Analyze the amino acids and acylcarnitines in the blood of patients first diagnosed with uremia using tandem mass spectrometry in order to provide a basis for clinical diagnosis and treatment. Methods 30 patients with uremia were ...
Evaluation of Antimicrobial Efficacy of Local Drug Resistance Spectrum Antibiotics and Foreign Guideline on Community Acquired Pneumonia
Li Jian Hua
2016, 37(05)
Abstract(2856) PDF(200) Cited By (9)
Abstract:
[Abstract]Objective To evaluate the clinical efficacy of the local drug resistance spectrum antibiotics and foreign guideline in the treatment of patients with community acquired pneumonia(CAP). Methods A prospective,randomized,single blind,and posit...
Clinical Assessment on the Safety of Cardiac Rehabilitation for the Elderly Patients with Chronic Heart Failure
Luo Yong Li
2016, 37(05)
Abstract(3355) PDF(188) Cited By (14)
Abstract:
[Abstract]Objective To evaluate the safety of cardiac rehabilitation (CR) for the elderly patients with chronic heart failure(CHF). Methods All 72 patients with CHF over the age of 60 were enrolled and randomly divided into two groups: the experiment...
鼠神经生长因子联合红花黄素治疗老年糖尿病合并脑梗
Du Hai Yan
2016, 37(05)
Abstract(2369) PDF(199) Cited By (4)
Abstract:

[摘要]目的 观察鼠神经生长因子联合红花黄素治疗老年糖尿病合并脑梗塞的疗效.方法 纳入观察的80例老年糖尿病合并脑梗患者随机分为2组,Ⅰ组给予氧疗、应用脱水剂、控制血糖、阿司匹林,调脂,维持电解质平衡, 红花黄素注射液治疗.Ⅱ组在Ⅰ组的基础上加鼠神经生长因子.治疗15 d后对比疗效. 结果 治疗前后症状和神经功能评分差异有统计学意义(P<0.05).结论 鼠神经生长因子联合红花黄素治疗老年糖尿病合并脑梗有效,值得临床推广.

Effects of Different Ventilation Modes on Respiration and Circulation in Elderly Patients Undergoing Thoracic Surgery
Deng Li Qiang
2016, 37(05)
Abstract(2829) PDF(194) Cited By (3)
Abstract:
[Abstract]Objective The aim of this study was to explore the effects of volume controlled ventilation (VCV),pressure controlled ventilation(PCV)and pressure controlled ventilation-volume guaranteed (PCV-VG)on respiration and circulation in elderly pa...
Clinical Study of Low Molecular Weight Heparin Combined with Alteplase for Thrombolysis
Li Ting Ting
2016, 37(05)
Abstract(2239) PDF(205) Cited By (4)
Abstract:
[Abstract]Objective The aim of this study was to investigate the application of low molecular weight heparin combined with alteplase for thrombolysis in patients with acute myocardial infarction(AMI),and to compare its thrombolysis effect with tradit...
The Clinical Value of Dual-source CT in the Diagnosis of Coronary Artery Fistula before and after Surgery
Sun Gui Fang
2016, 37(05)
Abstract(2793) PDF(185) Cited By (2)
Abstract:
[Abstract]Objective The aim of this study was to explore the clinical value of dual-source CT (DSCT) in the diagnosis of coronary artery fistula (CAF) before and after surgery. Methods A retrospective analysis was performed in 15 cases of patients wi...
The Application of Temporary Balloon Occlusion of the Abdominal Aorta in High-order Position Sacral Tumor Surgical Operation
Ma Xiang
2016, 37(05)
Abstract(3237) PDF(193) Cited By (2)
Abstract:
[Abstract]Objective To evaluate temporary balloon occlusion of the abdominal aorta in high-order position sacral tumor surgical operation as a useful adjuvant technique.Methods Reviewed 79 cases of patients from 2005 to 2015 treated in our department...
Clinical Effect of EaLeSu on CIN Ⅱ~Ⅲ Patients with HPV Infection Treated with LEEP
Han Rui Ying
2016, 37(05)
Abstract(2228) PDF(236) Cited By (1)
Abstract:
[Abstract]Objective To investigate the clinical effect of EaLeSu on cervical intraepithelial neoplasia (CIN Ⅱ~Ⅲ)patients with HPV infection treated with loop electrosurgical excision procedure (LEEP). Methods 165 cases of CIN Ⅱ~Ⅲ patients with HPV in...
Applied Research of CT Perfusion Imaging on the Diagnosis of Splenic Diseases
Sun Li Hui
2016, 37(05)
Abstract(3099) PDF(256) Cited By (2)
Abstract:
[Abstract]Objective To discuss the applied research of CT perfusion imaging on the diagnosis of splenic diseases. Methods 20 patients with splenic diseases which accepted treatment in our hospital from January 2012 to December 2014 were assigned into...
Curative Effect Observation in the Treatment of Distal Humeral Shaft Fracture with Double Steel Plate Internal Fixation
Cheng Gang
2016, 37(05)
Abstract(3179) PDF(192) Cited By (12)
Abstract:
[Abstract]Objective To investigate the curative effect of the treatment for the distal humeral shaft fracture with double steel plate internal fixation. Methods A total of 60 individuals who were humeral shaft fractures were included from March 2009 ...
Effect of Hemoperfusion on Inflammation Factors in Patients with Sepsis
Teng Yan
2016, 37(05)
Abstract(3130) PDF(219) Cited By (13)
Abstract:
[Abstract]Objective To observe the changes of inflammatory factors and clinical parameters on septic patients with hemoperfusion,and to discuss the application of hemoperfusion on sepsis. Methods 43 patients with sepsis were divided into treatment gr...
Principle and Application Progress of CRISPR-Cas9
Yang Jia Ru
2016, 37(05)
Abstract(5537) PDF(2339) Cited By (18)
Abstract:
[Abstract]Recently,a fast developing new technology for gene modification named as CRISPR-Cas9 which based on CRISPR-Cas9 system composed of clustered regulatory interspaced short palindromic repeat(CRISPR) and Cas9 nuclease(CRISPR associated system ...
The Research Progress of Application of Epigenetics in Forensic Science
Zhao Li Juan
2016, 37(05)
Abstract(3441) PDF(252)
Abstract:
[Abstract]Epigenetics is the study of heritable changes in gene expression other than the changes in the underlying DNA sequence. Such changes include DNA methylation,genomic imprinting,X chromosome inactivation and non-coding RNA regulation. Recent ...
Polymorphism Investigation on 15 STR Loci of Yunnan Bai Population
Tang Wei
2016, 37(05)
Abstract(2068) PDF(361) Cited By (5)
Abstract:
[Abstract]Objective The study aimed to investigate 15 autosomal loci polymorphism (such as D3S1358 and TPOX) in Nujiang Bai nationality, in order to construct genetic basic data of Bai population and provide a foundation for population study and fore...
Simultaneous Determination of Phenobarbital, Ibuprofen and Nikethamide in the Biomaterial with GC-MS
Wang Shang Wen
2016, 37(05)
Abstract(2162) PDF(278) Cited By (2)
Abstract:
[Abstract]Objective The study aimed to establish a kind of simple,rapid,accurate and reliable method in order to simultaneous determine the phenobarbital,ibuprofen and nikethamide in the biomaterial. Methods The biomaterial were pre-treated with etha...
Impact of "Comparative Case Learning" on Medical Students' Analytical Ability in Clinical Case
Li Xia
2016, 37(05)
Abstract(2504) PDF(167)
Abstract:
[Abstract]Objective Pathophysiology has high comprehensiveness and practical characteristics. Developing analytical capacity is a major teaching aim of Pathophysiology. This study was aimed to build up the basic knowledge of pathophysiology and devel...
A Survey of Professional Cognitive Level and Its Influencing Factors of Fresh Nursing Students in Yunnan
Zheng Wen Li
2016, 37(05)
Abstract(2133) PDF(239) Cited By (1)
Abstract:
[Abstract]Objective The aim of this study was to investigate the professional cognitive level and its influencing factors of fresh nursing students in Yunnan,in order to provide a basis for nursing education workers, improve the situation and put for...
Comparison of Clinical Training Outcomes between the Synthetic and Traditional Teaching Modes
Xiong Ping
2016, 37(05)
Abstract(2641) PDF(170) Cited By (12)
Abstract:
[Abstract]Objective To evaluate the clinical training outcomes from two clinical practice modes for undergraduate students. Methods Total two grades 2009 and 2010, 150 undergraduate students were randomly divided into two groups: 69 students in group...
The Application of the Puncture Method of Indwelling Needle by Single Hand in Puncture Technique of Pediatrics
Zhou Yu E
2016, 37(05)
Abstract(2082) PDF(215) Cited By (12)
Abstract:
[Abstract]Objective To investigate the application effect of the puncture method of indwelling needle by single hand in clinical attendance of pediatrics. Methods From March 2015 to September 2015, 578 patients in our pediatrics were randomly and equ...