[1]章玲, 张衡, 孙秉贵.星形胶质细胞在阿尔茨海默病中的作用及其分子机制[J].2017, 29 (5) :501-506.
|
[2]沈婕, 李久胜.小胶质细胞在神经退行性疾病中的神经免疫调节作用[J].河南医学研究, 2017, 26 (2) :244-246.
|
[3]谭子健, 巨淑慧, 黄潇, 等.胶质细胞干细胞/前体细胞特性的研究进展[J].生理学报, 2017, 69 (2) :207-217.
|
[4]王茜, 程雪娇, 李学敏, 等.小胶质细胞在慢性神经退行性疾病中的作用研究进展[J].卫生研究, 2015, 44 (6) :1023-1027.
|
[5]蒋宏国.过表达Nurr1基因的小胶质细胞对神经干细胞向多巴胺能神经元分化的影响[D].昆明:昆明医科大学硕士论文, 2015.
|
[6]
|
[6]ZHANG P, LI W, LI L, et al.Treatment with edaravone attenuates ischemic brain injury and inhibits neurogenesis in the subventricular zone of adult rats after focal cerebral ischemia and reperfusion injury[J].Neuroscience, 2012, 201 (1) :297-306.
|
[7]邱奥望, 刘展, 郭军, 等.神经炎症与神经退行性疾病的关系[J].生理科学进展, 2011, 42 (5) :253-258.
|
[8]
|
[8]GLASS C K, SAIJO K, WINNER B, et al.Mechanisms underlying inflammation in neurodegeneration[J].Cell, 2010, 140 (6) :918-934.
|
[9]
|
[9]GUO L, LJ L D M E.A Dual role for apolipoprotein E in neuroinflammation anti-and pro-inflammatory activity[J], Journal of Molecular Neuroscience, 2004, 23 (3) :205-212.
|
[10]
|
[10]GUO L, SAWKAR A, ZASADZKI M, et al.Similar activation of glial cultures from different rat brain regions by neuroinflammatory stimuli and downregulation of the activation by a new class of small molecule ligands[J], Neurobiology ofAging, 2001, 22 (6) :975-981.
|
[11]
|
[11]RALAY R H, CRAFT J M, HU W, et al.Glia as a therapeutic target:Selective suppression of human amyloid-β-induced upregulation of brain proinflammatory cytokine production attenuates neurodegeneration[J], The Journal ofNeurobiology, 2006, 26 (2) :662-670.
|
[12]
|
[12]WATTERSON DM, MIRZOEVA S, GUO L, et al.Ligand modulation of glial activation:Cell permeable, small molecule inhibitors of serine-threonine protein kinases can block induction of interleukin 1βand nitric oxide synthase II[J].Neurochemistry International, 2001, 39 (5-6) :459-468.
|
[13]
|
[13]PETROVA TV, AKAMA KT, LINDA J, et al.Cyclopentenone prostaglandins suppress activation of microglia:Down-regulation of inducible nitric-oxide synthase by15-deoxy-△12, 14-prostaglandin J2[J].Neurobiology, 1999, 96 (8) :4668-4673.
|
[14]
|
[14]JINGRU H U, FRANCIS CASTETS, JOSE L.GUEVARA, et al.S100βstimulates inducible nitric oxide synthase activity and m RNA levels in rat cortical astrocytes[J].THE JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (5) :2543-2547.
|
[15]辛岗, 苏芸, 许燕璇, 等.脂多糖活化小鼠大脑小胶质细胞后炎性细胞因子的表达[J].中国热带医学, 2011, 11 (8) :983-988.
|
[16]袁龙.脂多糖所介导的小胶质细胞活化的分子机制[D].延吉:延边大学硕士论文, 2012.
|
[17]
|
[17]ALOISI F, RIA F, ADORINI L.Regulatiol of T-cell responses by CNS antigen-pres enting cells:different roles for microglia and astrocytes[J].Immunology Today, 2000, 21 (3) :141.
|
[18] 乔廷廷, 郭玲.MAPK信号传导通路调控Amyloid-beta介导神经炎症中的过氧化物[J].昆明医科大学学报, 2016, 37 (2B) :309-313.
|
[19]姚惠亚, 张连生, 伍进, 等.依达拉奉对急性脑梗死患者神经元特异性烯醇化酶和C反应蛋白水平及预后的影响[J].中国医师杂志, 2012, 14 (3) :411-413.
|
[20]袁云, 李璠, 韩宏, 等.依达拉奉通过Notch信号通路调节BV-2小胶质细胞激活的研究[J].神经解剖学杂志, 2017, 33 (5) :560-566.
|
[21]王漫.JNK抑制剂SP600125对AD脑内突触损害和炎性反应治疗作用及其机制研究[D], 西安:第四军医大学硕士论文, 2015.
|
[22]
|
[22]AGTHONG S, KOONAMJ, KAEWSEMA A, et al.Inhibition of MAPK ERK impairs axonal regeneration without an effect on neuronal loss after nerve injury[J].Neurol Res, 2009, 25 (10) :1068-1074.
|
[23]刘婷婷, 张淑萍, 覃筱燕, 等.MAPK信号传导通路与神经损伤研究进展[J].中国公共卫生, 2016, 32 (2) :248-254.
|
[24]吴晓, 金茂强, 陈含笑.闭合性弥漫性脑损伤后IL-1β.P38MAPK及VCAM-1的动态表达及意义[J].新疆医科大学学报, 2011, 34 (1) :62-65.
|
[25]
|
[25]AVRAMOVICH Y, AMIT T, YOUDIM MB.Non-steroidal anti-inflammatory drugs stimulate secretion of non-amyloidogenic precursor protein[J].The Journal of Biological Chemistry, 2002, 277 (35) :31466-31473.
|
[26]
|
[26]WANG S D, CHEN B C, KAO S T, et al.Genistein inhibits tumor invasion by suppressing multiple signal transduction pathways in human hepatocellular carcinoma cells[J].BMCComplementary and Alternative Medicine, 2013, 14 (1) :1-26.
|
[27]
|
[27]TSAI J P, HSIAO P C, YANG S F, et al.Licochalcone Asuppresses migration and invasion of human hepatocellular carcinoma cells through downregulation of MKK4/JNK via NF-KB mediated urokinase plasminogen activator exprssion[J].PLoS One, 2014, 9 (1) :e86537.
|