2024 Vol. 45, No. 7

Expert Forum
Research Progress on the Molecular Pathogenesis of Temporomandibular Joint Osteoarthritis
Yihan CHEN, Shanyong ZHANG, Yu DING, Li ZHANG
2024, 45(7): 1-5. doi: 10.12259/j.issn.2095-610X.S20240701
Abstract(1443) HTML PDF(55)
Abstract:
Temporomandibular joint osteoarthritis (TMJOA) is a chronic degenerative condition affecting the structures of the temporomandibular joint. Despite ongoing research efforts, the pathogenesis of TMJOA is not yet fully understood. Recent advancements i...
Original Articles Basic of Medicine
Effects of HSV-1 Mutant Strain M6 on Macrophage-Mediated Immune Response after Infecting Human Bronchial Epithelial Cells
Zhenxiao ZHANG, Jingjing ZHANG, Yun LIAO, Dandan LI, Heng LI, Longding LIU
2024, 45(7): 6-13. doi: 10.12259/j.issn.2095-610X.S20240702
Abstract(960) HTML PDF(22)
Abstract:
Objective To explore the impact of herpes simplex virus type 1 (HSV-1) mutant strain M6 on macrophage-mediated immune responses after infecting human bronchial epithelial cells (16HBE cells). Methods HSV-1 infection of 16HBE cells was conducted to as...
Mechanism of Rosiglitazone in Reducing Liver Ischemia Reperfusion Injury in Rats by Inducing HO-1
Yihan YANG, Huamei CHEN, Yu FANG, Yuxin WANG, Xi ZHAN
2024, 45(7): 14-22. doi: 10.12259/j.issn.2095-610X.S20240703
Abstract(970) HTML PDF(15)
Abstract:
Objective To observe whether rosiglitazone, a peroxisome proliferator-activated receptor (PPAR-γ) agonist, can attenuate hepatic ischemia-reperfusion injury (IRI) in rats by modulating heme oxygenase 1 (HO-1) activity. Methods A rat 70% hepatic ther...
Changes of Genebody Methylation in Lingual Carcinogenesis
Hua LIU, Wanyuan YUE, Shuai SHAO, Jiaping SUN, Ying YANG, Xiaoming DAI
2024, 45(7): 23-29. doi: 10.12259/j.issn.2095-610X.S20240704
Abstract(899) HTML PDF(10)
Abstract:
Objective To evaluate differentially expressed genes with correlation of gene body methylation . Methods The lingual carcinogenesis was induced through the delivery of drinking water of 4-nitroquinoline-1-oxide(4NQO) with a density of 50 mg/L. The li...
Effect of Hsp90 Inhibitor Ganetespib Combined with Pemetrexed on Lung Adenocarcinoma Cells
Shengqiang YANG, Ping WANG
2024, 45(7): 30-41. doi: 10.12259/j.issn.2095-610X.S20240705
Abstract(420) HTML PDF(7)
Abstract:
Objective To investigate the effects of Ganetespib and Pemetrexed on the proliferation, apoptosis and related signaling pathways of human lung adenocarcinoma cells in vitro. Methods Human lung adenocarcinoma cells HCC827, H1975, and A549 were divided...
Analysis of the Clinicopathological and Molecular Features of Appendiceal Mucinous Neoplasms
Xuedan WANG, Yifan LIU, Zihan YANG, Dandan ZHANG, Yi DUAN, Zhihui YANG
2024, 45(7): 42-48. doi: 10.12259/j.issn.2095-610X.S20240706
Abstract(1855) HTML PDF(30) Cited By (1)
Abstract:
Objective To investigate the clinicopathological and molecular features of appendiceal mucinous neoplasms (AMNs), compare the differences bewteen the LAMN and HAMN. Methods 32 cases of AMNs were collected between January 2015 and September 2021. The...
Clinical Research
A Study of Risk Factors for the Effect of Allogeneic Hematopoietic Stem Cell Transplantation on Thyroid Function in Patients with Acute Leukemia
Jin HU, Ben NIU, Meng LI, Yanlin MA
2024, 45(7): 49-55. doi: 10.12259/j.issn.2095-610X.S20240707
Abstract(406) HTML PDF(15)
Abstract:
Objective To investigate the incidence and identify risk factors associated with thyroid disease (TD) in patients diagnosed with acute leukemia (AL) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods Clinical data of 9...
Comparison of Effect of Microscopic Surgery via Different Approaches in Treatment of Young Patients with Severe Hypertensivebasal Ganglia Hemorrhage
Kun WANG, Jun PU, Tao YANG, Lu WANG, Dongbo LI
2024, 45(7): 56-61. doi: 10.12259/j.issn.2095-610X.S20240708
Abstract(888) HTML PDF(13) Cited By (2)
Abstract:
Objective To compare the effect of different approaches of microscopic surgery in the treatment of severe hypertensivebasal ganglia hemorrhage (HBGH) in young patients. Methods A retrospective analysis was performed on young patients with severe HBG...
Expression of EMC6,C-myc and BCL-2 in Cervical Cancer Tissues and Prognosis Analysis
Chunxia MIAO, Yina WANG, Yunxia ZHANG
2024, 45(7): 62-68. doi: 10.12259/j.issn.2095-610X.S20240709
Abstract(483) HTML PDF(11)
Abstract:
Objective This study employs bioinformatics analysis to evaluate the expression, immune correlation, and diagnostic value of EMC6 gene in pan-cancer and cervical cancer, and investigate the associations of EMC6, C-myc, and BCL-2 proteins with cervica...
Operation and Quality Evaluation of the Influenza Monitoring System in Yunnan Province,2021 to 2022
Lifen ZHANG, Xingchen WEI, Yanhong SUN, Jienan ZHOU, Xiaoyu HAN, Yaoyao CHEN
2024, 45(7): 69-72. doi: 10.12259/j.issn.2095-610X.S20240710
Abstract(445) HTML PDF(8)
Abstract:
Objective To analyze the operation of the influenza monitoring system in Yunnan Province from 2021 to 2022 and conduct quality evaluation, identify weak links and take targeted measures to improve the level of influenza monitoring works. Methods We ...
Molecular Characterization of the VP1 Region of Coxsackievirus 16 in Kunming,Yunnan in 2022
Lei ZHANG, Ru SHEN, Zhaoyang CHU, Shaohui MA, Li LI
2024, 45(7): 73-78. doi: 10.12259/j.issn.2095-610X.S20240711
Abstract(946) HTML PDF(12)
Abstract:
Objective To analyze the molecular characteristics of the whole VP1 gene region of coxsackievirus A16 (CVA16) isolated from children with hand, foot and mouth disease (HFMD) in 2022 from a hospital in Kunming, Yunnan. Methods Two hundreds fecal spec...
Investigation of Molecular Typing and Drug Resistance of Shigella in Yunnan Province from 2016 to 2022
Yanzhu YIN, Zushun YANG, Yanqiushuo ZOU, Xiang REN, Yidan GUO, Lu FAN
2024, 45(7): 79-86. doi: 10.12259/j.issn.2095-610X.S20240712
Abstract(1188) HTML PDF(9)
Abstract:
Objective To analyze the serum typing, PFGE molecular typing, and drug-resistance of Shigella strains isolated from the active surveillance for foodborne diseases in Yunnan province from 2016 to 2022, the aim is to understand the pathogen characteris...
Comparative Analysis of the Efficacy of Neuroendoscopic and Microscopic Transnasal Resection of Pituitary Tumours in the Pterygoid Region
Bijiang ZHANG, Jinghui LI
2024, 45(7): 87-91. doi: 10.12259/j.issn.2095-610X.S20240713
Abstract(1374) HTML PDF(13) Cited By (2)
Abstract:
Objective To analyze the clinical effectiveness of neuroendoscopy and microscopy in the treatment of hypophysectomy. Methods The clinical data of 150 patients with pituitary adenoma treated in the Department of Neurosurgery, the First Affiliated Ho...
Effect of Exoskeleton Robot-assisted Rehabilitation Training on Motor Function and Gait Ability in Patients with Stroke
Yu LI, Lin ZHU, Kerong CHEN, Yi LI, Zhongxiang YU, Chengyin WU, Hongling SHI
2024, 45(7): 92-98. doi: 10.12259/j.issn.2095-610X.S20240714
Abstract(578) HTML PDF(22) Cited By (2)
Abstract:
Objective To explore the effect of exoskeleton robot-assisted rehabilitation training on lower limb motor and walking function in patients with hemiplegia after stroke. Methods We recruited 36 patients with lower limb hemiplegia after stroke in the ...
Diagnostic Value of Combined Detection of Serum HBsAg,HBV RNA,GGT and GPR in the Natural History of Chronic HBV Infection
Wenjun YU, Tingting YU, Lihua LI, Hongying WANG, Dong PU, Yongrui YANG
2024, 45(7): 99-104. doi: 10.12259/j.issn.2095-610X.S20240715
Abstract(505) HTML PDF(26) Cited By (2)
Abstract:
Objective To investigate the changes of serum hepatitis B virus surface antigen (HBsAg), hepatitis B virus ribonucleic acid (HBV RNA), γ-glutamyl transpeptidase (GGT), γ-glutamyl transpeptidase to platelet ratio (GPR) levels in patients with differen...
Clinical Features and Prognosiss of Pediatric Acute Lymphoblastic Leukemia with Hyperleukocytosis
Haijin LI, Huiyuan LI, Xinmiao LIU, Yue TIAN, Na LI, Zhengcheng DUAN, Xin TIAN
2024, 45(7): 105-112. doi: 10.12259/j.issn.2095-610X.S20240716
Abstract(517) HTML PDF(12)
Abstract:
Objective To investigate the clinical features and prognostic factors of pediatric acute lymphoblastic leukemia with hyperleukocytosis (HL-ALL). Methods The clinical data of 427 newly diagnosed ALL children admitted to the Department of Hematology a...
The Mechanism of Acetylcysteine Aerosol Inhalation Combined with Non-invasive Ventilator NIPSV Mode in the Treatment of AECOPD with Respiratory Failure by Regulating Immune Inflammatory Response
Weihua ZHANG, Shanshan QIN, Sicong WEN, Pingyu WU, Zhaoguang SONG
2024, 45(7): 113-118. doi: 10.12259/j.issn.2095-610X.S20240717
Abstract(368) HTML PDF(5) Cited By (1)
Abstract:
Objective To explore the mechanism of acetylcysteine aerosol inhalation combined with non-invasive ventilator pressure supported ventilation (NIPSV) in the treatment of acute stage of chronic obstructive pulmonary disease (AECOPD) complicated with re...
Relationship between hs-CRP,CCL2,CCL3 and Neonatal Bacterial Infection and Their Predictive Value for Efficacy
Zhenxing YUAN, Wenfei SUN, Weidong WANG
2024, 45(7): 119-125. doi: 10.12259/j.issn.2095-610X.S20240718
Abstract(408) HTML PDF(6)
Abstract:
Objective To explore the application value of high-sensitivity C-reactive protein (hs-CRP), chemokine CC motif ligand (CCL), and CCL3 in the treatment of neonatal bacterial infections. Methods A total of 70 cases of neonatal bacterial infection admi...
Relationship between Levels of Serum 25-hydroxyvitamin D,Calcium,Zinc and Growth and Development of Children
Yuyu ZHANG, You LU, Yu LIU
2024, 45(7): 126-131. doi: 10.12259/j.issn.2095-610X.S20240719
Abstract(695) HTML PDF(9)
Abstract:
Objective To observe the levels of serum 25-hydroxyvitamin D, calcium and zinc in children, and explore the relationship between the three indexes and the growth and development of children. Methods From January 2021 to December 2022, 98 children wi...
Effect of Bobath Therapy Combined with Suspension Technique on the Rehabilitation of Children with Cerebral Palsy
Jing ZHAO, Dun LIU, Maolin LIAO, Hongyan LUO
2024, 45(7): 132-139. doi: 10.12259/j.issn.2095-610X.S20240720
Abstract(561) HTML PDF(24) Cited By (1)
Abstract:
Objective To explore the application value of Bobath therapy combined with the suspension technique in the rehabilitation treatment of children with cerebral palsy from the aspects of skeletal muscle development, gross motor function and limb balance...
Effect of Comprehensive Treatment on MiR-320,MiR-27a and Pregnancy Outcome in Infertile Patients with Polycystic Ovary Syndrome
Shan HE, Aiwen LE, Yang QIU, Bo ZHEN, Zhonghai WANG
2024, 45(7): 140-147. doi: 10.12259/j.issn.2095-610X.S20240721
Abstract(490) HTML PDF(6)
Abstract:
Objective To observe the effect of comprehensive treatment on reproductive hormones, MicroRNA(miRNA) and prognosis of infertile women with polycystic ovary syndrome (PCOS). Methods A total of 120 infertile PCOS patients admitted to Jiangmen Central ...
Value of High Field Tntensity MRIT1 Perfusion Imaging Combined with DWI Imaging in Evaluating The Efficacy of Neoadjuvant Chemotherapy for Breast Cancer
Zheng ZHANG, Yanhong YANG, Zaihui FENG, Lujiang ZHAN, Jinxian PU, Qianting DUAN
2024, 45(7): 148-153. doi: 10.12259/j.issn.2095-610X.S20240722
Abstract(418) HTML PDF(10)
Abstract:
Objective To assess the potential value of high-field MRI T1 perfusion imaging combined with diffusion-weighted imaging (DWI) in evaluating neoadjuvant chemotherapy efficacy in breast cancer. Methods The clinical and radiological data, including pre...
Forensic Medicine Research
Polymorphism Investigation of 23 Autosome STR Loci in the MicroreaderTM 23HS Plex ID System in Han Population in Northern China
Yan SHI, Jian JIANG, Chong CHEN, Jingjing ZHANG, Li JIA, Zhixiao GAO, Huifen LI, Jiangwei YAN, He REN
2024, 45(7): 154-159. doi: 10.12259/j.issn.2095-610X.S20240723
Abstract(558) HTML PDF(32)
Abstract:
Objective To obtain the distribution of allele frequency and population genetic data of 23 autosomal STR loci contained in the MicroreaderTM 23HS Plex ID System kit in the Han population of northern China, and explore its application value in forensi...
Reviews
Application of Time-Lapse Imaging Technology and Artificial Intelligence in ART
Yanrong HUANG, Mingying LI, Mengying GAO, Lifeng XIANG, Jiacong YAN, Yonggang LI
2024, 45(7): 160-167. doi: 10.12259/j.issn.2095-610X.S20240724
Abstract(839) HTML PDF(39)
Abstract:
Accurate assessment of embryo development is of paramount importance for the success of Assisted Reproductive Technologies (ART). Traditional methods predominantly rely on subjective embryo morphological evaluations, lacking objectivity and real-time...
Advancements in the Clinical Use of Antidepressants for Adolescent Depression
Haoran XING, Xi ZHANG, Yingying ZHANG, Tianhao BAO
2024, 45(7): 168-176. doi: 10.12259/j.issn.2095-610X.S20240725
Abstract(1440) HTML PDF(73) Cited By (4)
Abstract:
Compared with adult patients with depression, adolescents with depression have a higher incidence rate, poorer quality of life and poorer treatment effects. International guidelines generally recommend giving priority to psychological treatment for m...
Teaching Research
Construction and Application of Breast Imaging Teaching Software and Case Library Based on the OBE Concept
Yajie DONG, Zhaoxing LI, Qian GAO, Chunyan LUO, Wen ZHAO, Jun LI
2024, 45(7): 177-182. doi: 10.12259/j.issn.2095-610X.S20240726
Abstract(1500) HTML PDF(11)
Abstract:
Objective To construct breast imaging teaching software and case library based on the outcome-based education (OBE) concept, and explore the practical effects of teaching. Methods We randomly selected 81 undergraduate students who majored in medical...
Nursing Forum
Development of a Patient-reported Outcome Scale For Bladder Cancer and Test of Reliability and Validity
Yuqin LIU, Mingying YANG, Liufang WANG, Siya XIA, Danna LI, Xijuan ZHAO, Ya WANG
2024, 45(7): 183-190. doi: 10.12259/j.issn.2095-610X.S20240727
Abstract(446) HTML PDF(9)
Abstract:
Objective To develop a patient-reported outcome scale for bladder cancer suitable for Chinese culture and test its reliability and validity. Methods The initial scale was formed by literature review, semi-structured interview, cognitive test, and tw...