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miRNA在非酒精性脂肪性肝病中的研究进展

陈杭 崔琦 黄敏杉 刘建军 马岚青

陈杭, 崔琦, 黄敏杉, 刘建军, 马岚青. miRNA在非酒精性脂肪性肝病中的研究进展[J]. 昆明医科大学学报, 2024, 45(1): 1-7. doi: 10.12259/j.issn.2095-610X.S20240101
引用本文: 陈杭, 崔琦, 黄敏杉, 刘建军, 马岚青. miRNA在非酒精性脂肪性肝病中的研究进展[J]. 昆明医科大学学报, 2024, 45(1): 1-7. doi: 10.12259/j.issn.2095-610X.S20240101
Hang CHEN, Qi CUI, Minshan HUANG, Jianjun LIU, Lanqing MA. Research Progress of miRNA in Non-alcoholic Fatty Liver Disease[J]. Journal of Kunming Medical University, 2024, 45(1): 1-7. doi: 10.12259/j.issn.2095-610X.S20240101
Citation: Hang CHEN, Qi CUI, Minshan HUANG, Jianjun LIU, Lanqing MA. Research Progress of miRNA in Non-alcoholic Fatty Liver Disease[J]. Journal of Kunming Medical University, 2024, 45(1): 1-7. doi: 10.12259/j.issn.2095-610X.S20240101

miRNA在非酒精性脂肪性肝病中的研究进展

doi: 10.12259/j.issn.2095-610X.S20240101
基金项目: 国家自然科学基金资助项目(82160117)
详细信息
    作者简介:

    陈杭(1994~),男,四川宜宾人,在读博士研究生,主要从事消化系统、肝病研究工作

    崔琦与陈杭对本文有同等贡献

    通讯作者:

    马岚青,E-mail:malanqing@aliyun.com

  • 中图分类号: R575

Research Progress of miRNA in Non-alcoholic Fatty Liver Disease

More Information
    Corresponding author: 马岚青,医学博士,博士生导师,主任医师。现任昆明医科大学第一附属医院消化内科副主任(主持工作),昆明医科大学第一附属医院内科住院医师规范化培训基地主任,昆明医科大学第一附属医院内科教研室主任。美国加州大学圣地亚哥分校医学中心访问学者。中华医学会消化病学分会全国青年委员会委员;中华医学会消化病学分会肿瘤协助组委员;中国女医师协会消化病专业分会委员;云南省医院协会消化内科专业委员会主任委员;云南女医师协会消化病学分会主任委员;云南省医师协会消化医师分会副主任委员;云南省医学会消化病学分会委员;中国医师协会内镜医师培训学院导师。云南省中青年学术和技术带头人,云南省“万人计划”名医,云南省医学学科领军人才、带头人,云南省政府特殊津贴专家,国家自然科学基金评委。擅长消化内镜诊治技术如EMR/ESD/POEM/STER/EFTR、肝病、幽门螺杆菌感染性疾病及消化系统急、难、危重症诊治。主持4项国家自然科学基金及6项云南省自然科学基金项目,以第一作者及通讯作者发表SCI论文20余篇,总影响因子IF > 100,获国家级发明专利及新型实用专利5项,副主编及编委发表论著4部,获省级自然科学奖、科技进步奖一等奖、三等奖共5项。
  • 摘要: 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种最常见的慢性肝病,全球患病率约为30.05%~32.40%,并且与多种其他疾病密切相关。近年来,miRNA(microRNA,miRNA)作为无创生物标志物在NAFLD的发病机制和诊断中扮演了重要角色。miRNA是一种小分子RNA,通过控制靶基因的转录和翻译来调节基因表达和蛋白质合成。miRNA在脂肪代谢和胰岛素抵抗中都起着重要作用,并在NAFLD的发病机制中发挥着具体的调控角色。就miRNA在脂肪代谢、胰岛素抵抗、NAFLD发生发展中的作用及机制的作一综述。
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  • 收稿日期:  2023-12-20
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