2018 Vol. 39, No. 05

2018, 39(05): 6-6.
Abstract(2083) PDF(12)
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2018, 39(05): 77-77.
Abstract(1599) PDF(8)
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The Research of Monoclonal Antibody KMP1 Inhibited Bladder Cancer EJ Cell Lines Growth and Metastasis in Vivo
Yang Can , Gong Yu Hang , Wang Hai Feng , Li Hai Hao , Liu Jing Yu , Wang Wei , Wang Jian Song , Zuo Yi Gang , Chen Jian , Zhan Hui , Ding Ming Xia
2018, 39(05): 1-6.
Abstract(2828) PDF(91)
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Objective To research the monoclonal antibody KMP1 inhibited bladder cancer EJ cell lines growth and metastasis in vivo by bioluminescence imaging. Me thods Immunohistochemistry was used to determine the KMP1 binding to EJ and EJ-GFP cell lines. The ...
Mutation Analysis of CIB2 196C>T 272T>C and 297 C>G in Patients with Non-syndromic Hearing Impairment
Li Qi
2018, 39(05): 7-10.
Abstract(2307) PDF(43)
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Objective To investigate the gene mutations of calcium-and integrin-binding protein 2 (CIB2) 196 C>T, 272 T > C and 297 C > G carried by students with non-syndromic hearing impairment from special educational schools in Yunnan Province. Me t...
A Novel Derivative of Panax Notoginseng Sapogenin and Its Antitumor Activity
Li Rui , Duan Wen Yue , Zou Cheng , Zhao Qing , Huang Li , Zhou Jin Na , Hu Jian Lin , Yang Wei Min
2018, 39(05): 11-15.
Abstract(1858) PDF(198)
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Objective To research the derivatives of panax notoginseng sapogenins and their anti-tumor activities. Me thods The ginsenosides Rg1 was treated with Smith degradation. The products were separated and purified by silica gel column chromatography. The...
Tissue Distribution of Yunaconitine in Rats by UPLC-MS/MS Method
Lu Fa Huan , Li Ji Yin , Li Shu Hua , Zhao Wen Song , Wang Rui , Jie Run Fang , Yang Kai Run
2018, 39(05): 16-20.
Abstract(1950) PDF(152)
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Objective To establish an acute yunaconitine poisoning rat model with a single oral administration and to determine the contents of yunaconitine in rat tissues by UPLC-MS/MS method, then investigate the distribution of yunaconitine in rats. Me thod T...
The Experimental Study of Cyasterone on the Treatment of Osteoporosis through the Bidirectional Effect of Inhibiting Osteoclast Differetiation and Promoting Osteoblast Differentiation
Ji Qin Long , Kong Xiang Dong , Qi Shan Hong , Li Chao , Fan Jun , Sha Yong , Wang Shao Feng
2018, 39(05): 21-28.
Abstract(2287) PDF(124)
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Objective To explore the influence of cyasterone on the osteoclast and osteoblast differentiation and then to investigate its effect on the bone quality in the osteoporosis mice. Me thods CCK8 assay was firstly used to detect the toxic effect of cyas...
The Regulatory Effect of PPARy in the Apoptosis against Renal Cell Carcinoma
Ye Lei , Tong Fa Chun , Li Jian , Wang Long , Zhao Jiang Ming , Liu Yi , Wang Jian
2018, 39(05): 29-34.
Abstract(2358) PDF(111)
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Objective To explore the effects of PPARγ agonist rosiglitazone and inhibitor T0070907 on apoptosis and anti-tumor in renal carcinoma A498 cells.Me thods A498 cells were divided into three groups and PBS, rosiglitazone (50 μmol/L) and T0070907 50 (μm...
Influence Factors and Countermeasures on the Ability of Kunming Medical University Graduates' Social Adaptation
Chang Wei , Yang Jun Fen , Wu Lin Xiong , Zhou Mei
2018, 39(05): 35-38.
Abstract(2414) PDF(95)
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Objective to understand the current situation of the social adaptation ability of Kunming Medical University graduates and to explore the possible influence factors, so as to provide some references for the school to formulate effective countermeasur...
The Training Effect of Ability to Timely Screening for Congenital Heart Disease among Primary Medical Workers in Yunnan Province
Zhao Shu Yan , Sun Huang , Sun Jie , Pan Jia Hua , Guo Tao , Zhao Ling , Li Ya Ni , Peng Yun Zhu , Yang Zu Huan
2018, 39(05): 39-44.
Abstract(2009) PDF(54)
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Objective To improve the early diagnosis of congenital heart disease (CHD) , investigate the awareness, screening knowledge and screening ability of CHD among health care providers in the rural areas of Yunnan province and discover an effective way t...
Expression and Significance of Plasma miR-223-3p in Diabetic Kidney Diseaseat Different Stages
He Jun Yi , Li Lan , Li Rong , Huang Yun Hua , Yang Qiu Ping , Wu Ya Nan , Zhang Li Hua
2018, 39(05): 45-49.
Abstract(2037) PDF(88)
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Objective To explore the expression of miR-223-3 p in the plasma of patients with diabetic kidney disease and its clinical significance. Me thods The expression levels of plasma miR-223-3 p in normoalbuminuric group (DM) , microoalbuminuria group (Mi...
Evaluation of Arterial Elasticity, Left Ventricular Function and Correlation by 256-slice Spiral CT in Patients with Aortic Dissection
Du Zi Hong , Sun Yong
2018, 39(05): 50-55.
Abstract(2622) PDF(59)
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Objective Using the function of 256-layer i CT in the determination of cardiac function and arterial elasticity index, to compare the arterial elasticity, left ventricular function and their correlation between patients with aortic dissection and non...
Comparison of Different Dosages of Rocuronium on Abdominal Wound Closure
Liao Fei , Qu Qi Cai , Huang Qing Qing , Tao Jian Ping , Si Yong Yu
2018, 39(05): 56-60.
Abstract(1532) PDF(64)
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Objective To evaluate the effects of different dosages of rocuronium on abdominal wound closure under general anesthesia.Me thods Ninety ASA class I or II patients scheduled for elective abdominal surgery under general anesthesia were randomized into...
Etiological Analysis of Community-acquired Lower Respiratory Tract Infection in Children in Kunming
Zhao Lin , Cao Li Yun , Lv Gao Jie , Li Ming Pan
2018, 39(05): 61-65.
Abstract(2804) PDF(77)
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Objective To investigate epidemiological characteristics of pathogenic bacteria of community-acquired lower respiratory tract infection in children in Kunming (with an altitude of 1860 m) .Me thods The results of bacterial culture of 9793 patients wi...
Research of the Pharmacokinetics and Pharmacodynamics of Torasemide in the Treatment of Children Patients with Acute Heart Failure
Xiao Qun Wen , Yang Long , He Xiang Ying , Li Qi , You Jun
2018, 39(05): 66-69.
Abstract(2137) PDF(76)
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Objective To investigate the pharmacokinetics and pharmacokinetics of torsemide in children with acute heart failure.Me thods Ninety cases of children with acute heart failure patients were randomly divided into three groups which were given differen...
Association Analysis between Genetic Polymorphisms of CYP4A11, Apolipoprotein B and E Genes and Essential Hypertension Susceptibility
Lu Die Qing
2018, 39(05): 70-77.
Abstract(2283) PDF(64)
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Objective To investigate the association between single nucleotide polymorphisms (SNPs) in CYP4A11 and Apo B、 Apo E genesandthe risk of essential hypertension. Me thods By means of correlation analysis, this case-controlled study included a total of ...
Clinical Contrastive Study between Caudal-to-crainal and Medial-to-lateral Approaches for Laparoscopic Right Hemicolectomy
Shu Ruo , Liu Tong Lei , Tian Yan , Fang Shi Xu , Luo Hua You
2018, 39(05): 78-82.
Abstract(2444) PDF(81)
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Objective To compare the short-term therapeutic effects of the caudal-to-crainal and medial-to-lateral approaches for laparoscopic right hemicolectomy. Me thod The clinical data of 124 patients underwent laparoscopic right hemicolectomy in the depart...
Application of 3D Printing Combined with S-ROM Total Hip Arthroplasty in the Treatment of Adult Crowe Ⅳ DDH
Yang Jia , Yang Yi , Zhao Yun Hong , Zhang Zheng Xue , Yang Qing , Yang Liu , Xi Ying Long , Duan Yu Ping , Li Biao
2018, 39(05): 83-89.
Abstract(2101) PDF(113)
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Objective To investigate the application of 3 D printing combined with S-ROM total hip arthroplasty in the treatment of adult Crowe IV DDH. Me thods Between September 2014 and June 2017, 10 patients of adult Crowe IV DDH were selected and divided int...
A Clinical Features Analysis of 1 000 Cases of Colorectal Cancer in Yunnan Tumor Hospital
Zhao Min , Zhang Qiang , Ma Yong Ci , Long Fei , Lin Yan Ping , Xu Xue Bin , Zhang Jin Ping
2018, 39(05): 90-93.
Abstract(2967) PDF(105)
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Objective To study the characteristics of colorectal cancer patients in Yunnan Tumor Hospital, and to provide the basis for the prevention and treatment of colorectal cancer. Me thods Retrospective analysis was used to review colorectal cancer patien...
A Clinical Analysis of 554 Cases of Partial Tubeless mPCNL
Jiang Yong Ming , Guo Hai Xiang , Mishra Prashant, Chen Jian , Li Jiong Ming , Wang Jian Song
2018, 39(05): 94-99.
Abstract(2163) PDF(46)
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Objective To summarize the experience of partial tubeless mPCNL. Methods A retrospective analysis of partial tubeless mPCNL surgery experience from January 2010 to December 2016. Atotal of 1320 patients underwent mPCNL surgery in these 7 years.Out fo...
急性下消化道大出血患者急诊肠镜诊断效果及其影响因素
He Han
2018, 39(05): 100-105.
Abstract(2556) PDF(65)
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目的 分析急性下消化道大出血患者急诊肠镜诊断效果及影响因素.方法 选取凉山彝族自治州第一人民医院2016年5月至2017年5月收治的56例急性下消化道大出血患者, 均行急诊结肠镜检查, 分析急性下消化道大出血病因, 比较不同肠道准备方法、不同出血程度患者急诊肠镜检查完成情况, 依据急诊肠镜检查成功与否分为检查成功组、检查失败组, 比较2组临床资料, 分析影响急诊肠镜检查的影响因素.结果 急性下消化道大出血病因有结肠癌、结肠息肉、结肠憩室等;不同肠道准备方法诱发再出血或出血加重率无明显差异 (P&...

Clinical Significance of MIP-1α and VEGF Levels in Serum and CSF of ALS Patients
Li Guo Lin , Li Chao , Li Feng
2018, 39(05): 106-110.
Abstract(1688) PDF(35)
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Objective Through the detection of MIP-1α and VEGF levels in serum and CSF of ALS patients, we evaluated the clinical value of MIP-1 and VEGF levels in ALS patients. Me thods A total of 80 patients with ALS were collected from Kuangwu Hospital of Ton...
A Study on the Effects of Cold Knife Excision by Hysteroscopy for the Local Microcirculation and Inflammatory Reaction of Patients with Hysteromyoma
Wei Jiang Xia , Wang Mei , Liu Gui , Dai Xue Mei
2018, 39(05): 111-114.
Abstract(2399) PDF(60)
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Objective To study and observe the effects of cold knife excision by hysteroscopy for the local microcirculation and inflammatory reaction of patients with hysteromyoma.Me thods 86 patients with hysteromyoma admitted in our hospital from March 2016 t...
A Treatment Effect Study of Arthroscope Combined Proximal Humerus Osteotomy in Knee Inversion Osteoarthritis
Feng Yong Quan , Wang Jian Long , Liu Yang , Rao Lei
2018, 39(05): 115-119.
Abstract(2596) PDF(43)
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Objective To discover the treatment effect of arthroscope combined with proximal humerus osteotomy in Knee inversion osteoarthritis.Me thods From April 2012 to December 2016, 126 cases were diagnosed with knee inversion osteoarthritis in our deparmen...
An Analysis on HCV Treatment Efficacy among HIV/HCV Co-infected Patients
Gu Shan Qun , Li Zhong Xi , Bai Jing Song , Tian Bo , Yu Min , Liu Jun
2018, 39(05): 120-123.
Abstract(1645) PDF(47)
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Objective To observe the efficacy and safety of DAAs in treating HCV patients with HIV/HCV co-infection.Me thod 53 patients were divided into groups based on HCV genotype. Sofosbuvir + Ledipasvir regime were used for 1 b and 6 a subtypes; sofosbuvir ...
Research Progress of the Relationship of the Expression of TAR DNA/RNA-binding Domain Protein 43 in Neurodegenerative Disease and Brain Injury
Cai Bin , Song Hai , Wang Zhen , Han Xue , Yu Jian Yun
2018, 39(05): 124-127.
Abstract(1628) PDF(173)
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TAR DNA/RNA-binding domain protein 43 (TDP-43) is a highly conserved and widely expressed nuclear protein. TDP-43 is recognized as a pathological marker protein of amyotrophic lateral sclerosis (ALS) , frontotemporal lobar degeneration (FTLD) and alz...
Progress in the Treatment of Acquired Hemophilia A
Lin Huan , Li Cheng Ping , Wu Bing Fen , Ran Li
2018, 39(05): 128-131.
Abstract(1765) PDF(232)
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Acquired hemophilia A is a deficiency disease caused by blood coagulation factor VIII antibodies due to a variety of causes, The disease incidence rate is extremely low, but the mortality rate is high. This disease is often misdiagnosed, resulting in...
The Effect and Its Factors of Autonomy Learning and Its Influencing Factors on the Postgraduates for Professional Degree Education
Zhao Lin , Chen Shan , Fan Yue Hong , Wang Jin De , Zhang Xiao Xian , Cai Xi Rui , Zhang Hong Bin , Liu Wei
2018, 39(05): 132-137.
Abstract(1807) PDF(97)
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Objective To evaluate the effect and its factors of the postgraduates' autonomy learning in medical English, and to suggest improving methods. Me thods The postgraduates enrolled in Kunming Medical University in 2016 were divided into two groups. Tho...
Participatory Teaching Class for MBBS Students
Lei Wen , Wu Wen Juan , Li Zhen Kun , Li Jing , Yang Mei Juan , Dong Zhao Xing
2018, 39(05): 138-140.
Abstract(2911) PDF(100)
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Objective To determine the effect of participatory teaching method in the Clinic teaching of internal medicine for MBBS students. Me thods The 60 MBBS students were divided into group A and B, 30 students in each group. Participatory teaching was don...
The Design and Practice in "four in two" Basis of Life Integrated Curriculum
Yang Fang , Yang Yin Feng , Li Qing , Di Yong , He Yong Shu , Zhu Yue Chun
2018, 39(05): 141-144.
Abstract(2038) PDF(57)
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Objective To explore the thinking and methods of integration curriculum. Methods The content of theory and experiment of the biochemistry, molecular biology, cell biology, medical genetics are optimized, streamlined and integrated to form theory cour...
The Clinical Effects of Cognitive Behavior Nursing Model on Glaucoma Patients
Zhao Jun Ying , Ma You Ni
2018, 39(05): 145-148.
Abstract(2564) PDF(50)
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Objective To explore the nursing effects of cognitive behavior nursing model in glaucoma patients and its influence on self-management behavior and long-term efficacy. Me thods 102 cases of glaucoma patients who were admitted to the Department of-201...