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炎症性肠病的肠道微生态变化及对策

李波 孙杨 缪应雷

李波, 孙杨, 缪应雷. 炎症性肠病的肠道微生态变化及对策[J]. 昆明医科大学学报, 2024, 45(4): 1-8. doi: 10.12259/j.issn.2095-610X.S20240401
引用本文: 李波, 孙杨, 缪应雷. 炎症性肠病的肠道微生态变化及对策[J]. 昆明医科大学学报, 2024, 45(4): 1-8. doi: 10.12259/j.issn.2095-610X.S20240401
Bo LI, Yang SUN, Yinglei MIAO. Intestinal Microecological Changes and Therapeutics in Inflammatory Bowel Disease[J]. Journal of Kunming Medical University, 2024, 45(4): 1-8. doi: 10.12259/j.issn.2095-610X.S20240401
Citation: Bo LI, Yang SUN, Yinglei MIAO. Intestinal Microecological Changes and Therapeutics in Inflammatory Bowel Disease[J]. Journal of Kunming Medical University, 2024, 45(4): 1-8. doi: 10.12259/j.issn.2095-610X.S20240401

炎症性肠病的肠道微生态变化及对策

doi: 10.12259/j.issn.2095-610X.S20240401
基金项目: 国家自然科学基金资助项目(U1802282;82060107)
详细信息
    作者简介:

    李波(2000~ ),女,白族 ,云南大理人,在读硕士研究生,主要从事炎症性肠病与肠道微生态研究工作

    通讯作者:

    缪应雷,E-mail:myldu@sina.com

  • 中图分类号: R574

Intestinal Microecological Changes and Therapeutics in Inflammatory Bowel Disease

More Information
    Corresponding author: 缪应雷,昆明医科大学第一附属医院主任医师,博士生导师,博士。国家百千万人才工程人选、国家有突出贡献中青年专家、国务院政府特殊津贴、云岭学者、云南省“名医”、 云南省医学会消化病学分会-主任委员、国家临床重点专科负责人。主持国家自然科学基金6项(其中重点项目1项),获云南省政府颁发的省级科技进步一等奖2项,三等奖6项。以第一作者或通讯作者发表SCI论文47篇,其中以通讯作者在《Gastroenterology》(IF= 33.883)发表论著2篇、《Cell Host & Microbe》(IF=31.316)发表论著1篇。
  • 摘要: 炎症性肠病(inflammatory bowel disease,IBD)是1种慢性疾病,其特征是反复发作的肠道炎症,尽管具体原因尚未完全明确,但普遍认为它是由遗传、免疫系统异常、环境因素和肠道微生物群失衡等多重因素共同作用引起的。这些因素的相互作用可能会导致肠道环境稳态受损,进而影响宿主的免疫,最终触发肠道炎症。综述IBD患者肠道微生物群的变化情况,并探讨相应的治疗对策。
  • 图  1  基于肠道微生态的IBD治疗策略

    Figure  1.  Current microecological‐based therapeutic strategies in IBD

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  • 收稿日期:  2024-04-10
  • 网络出版日期:  2024-04-21
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