2021 Vol. 42, No. 1

Original Articles Basic of Medicine
The Effect of Peptide-prolinyl Isomerase(Pin1)on Lipid Metabolism in Cervical Cancer Cells
Li-jun HAO, Li-xiu XU, Jin-qiu LI, Jun-qi MA, Hasimu AXIANGU
2021, 42(1): 12-16. doi: 10.12259/j.issn.2095-610X.S20210111
Abstract(3085) HTML PDF(25) Cited By (4)
Abstract:
Objective To investigate the effect of peptide-based prolinyl isomerase(Pin1)protein on lipid metabolism in cervical cancer cells. Methods The expression of Pinl and ACC1 protein in chronic cervical cancer and cervical cancer tissues was detected b...
The Regulation of Exosome Derived from Human Bone Marrow Mesenchymal Stem Cells on the Polarization of Glioma-associated Macrophages
Xiao CAI, Xue-tao YI, Jing-qing YAO, Xin-yu DAI, Zhong-quan TANG, Ting OU, Xiao-min ZHAO, Yun-tao LI
2021, 42(1): 38-45. doi: 10.12259/j.issn.2095-610X.S20210101
Abstract(3599) HTML PDF(38) Cited By (2)
Abstract:
Objective To investigate the effect of exosomes divided from human bone marrow mesenchymal stem cells on the polarization of tumor-associated macrophages, and to preliminarily discuss their influence on glioma cell lines. Methods Exosomes divided f...
Expression of MCM7 Protein during the Spermatogenesis of Artificially Domesticated Tree Shrew
Guang-yong HE, Jian TANG, Fang YANG, Zhong-yi QIAN, Yu-ling YANG, Lan LUO
2021, 42(1): 1-5. doi: 10.12259/j.issn.2095-610X.S20210112
Abstract(2728) HTML PDF(111)
Abstract:
Objective To study the expression characteristics of MCM7 protein during spermatogenesis of artificially domesticated tree shrews and whether there are seasonal differences in its expression, so as to provide basic experimental data for reproductive ...
Comparative Study on Anti-inflammatory and Antimicrobial Effects for Two Kinds of the Resin Gel
Li-han YANG, Zhi-bi ZHANG, Hui YANG, Jiang-lan YANG, Dan MAO, Xiao-li YANG, Chao-yu LUO, Yuan ZHANG, Rong-ping ZHANG
2021, 42(1): 6-11. doi: 10.12259/j.issn.2095-610X.S20210134
Abstract(4769) HTML PDF(26) Cited By (10)
Abstract:
Objective To comparatively study the anti-inhibitory and bacteriostatic effects of RDD and RDC gel so as to provide the laboratory basis for the development and utilization of the resin. Methods The model of the mouse pinna swelling induced by xylene...
Process Studies on the Surface Modification of Coral Hydroxyapatite
Jia-he CHANG, Jing LI, Jun SU, Li-jia HE, Qing-hua CHEN, Wen-yun ZHANG
2021, 42(1): 17-22. doi: 10.12259/j.issn.2095-610X.S20210106
Abstract(2380) HTML PDF(27)
Abstract:
Objective To explore the process of modifying coral hydroxyapatite by nmZnO under the different conditions. Methods Coral hydroxyapatite was modified by zinc nitrate sol-gel method at 70 ℃ in weak acid environment. White granular porous composite mat...
OCT Evaluation on the Establishment of A Mouse Model of Chronic Ocular Hypertension Induced by Magnetic Beads Injection
Xiu-qiang YAN, Xiao-fan ZHANG, Yu-ling REN, Juan-juan LI, Li-wei ZHANG
2021, 42(1): 23-28. doi: 10.12259/j.issn.2095-610X.S20201245
Abstract(3808) HTML PDF(50)
Abstract:
Objective To explore the feasibility and characteristics of magnetic microbead anterior chamber injection inducing ocular hypertension model, and to study the role of OCT in model evaluation. Methods C57BL/6 mice were divided into the normal group, c...
A Clinical Scoring System Predicting the Osteosarcoma Chemotherapy Drug Resistance
Ling ZHOU, Feng-di HU, Rong LI, Ye-dan LIAO, Zheng-qin GENG, Jia-dai TANG, Xue-qi ZHANG, Lin XIE, Zuo-zhang YANG
2021, 42(1): 29-37. doi: 10.12259/j.issn.2095-610X.S20210144
Abstract(3627) HTML PDF(22) Cited By (1)
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Objective The purpose of this study was to develop a scoring system to predict chemotherapy resistance of osteosarcoma, which could guide doctors to better choose the appropriate treatment. Methods 119 cases of osteosarcoma with neoadjuvant chemother...
Effect of Tumor Antigen Loaded DC-CIK on Microenvironment of Hepatocellular Carcinoma
Da-guang TIAN, Heng-hai YU, Xiao-ping WEI
2021, 42(1): 46-50. doi: 10.12259/j.issn.2095-610X.S20210127
Abstract(4403) HTML PDF(24) Cited By (2)
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Objective To study the effect of tumor antigen loaded DC-CIK on the microenvironment of hepatocellular carcinoma. Methods The antigen of HCC coming from resected HCC and peripheral blood mononuclear cells were isolated from healthy donors. The cells ...
Healthy Lifestyles and Impact Factors of Students from Medical Colleges in Yunnan
Yang WANG, Jun LI, Jun TONG, Min-li YANG
2021, 42(1): 51-58. doi: 10.12259/j.issn.2095-610X.S20210103
Abstract(3335) HTML PDF(20) Cited By (12)
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Objectives To investigate and analyze the health lifestyle of medical students and the impact factors of social and demographic characteristics. Methods A total of 2, 278 medical students were randomly selected and their health lifestyle information ...
An Analysis of Influencing Factors for COPD Patients Re-admission to Hospital in Yunnan Province Based on DRGs
Rui FU, Le CAI
2021, 42(1): 59-63. doi: 10.12259/j.issn.2095-610X.S20210110
Abstract(2990) HTML PDF(16) Cited By (3)
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Objective The aim of this study is to analyze the factors affecting re-admission to hospitals of the patients with chronic obstructive pulmonary disease(COPD)in Yunnan province based on the diagnosis related groups(DRGs). Methods Clustering sampling ...
Clinical Research
Expression and Significance of Serum HIF-1α in Patients with Chronic Kidney Disease
Shu-yun YANG, Min JI, Wen-xi ZHAO, Xiao-na LI, Rui LI, Dai-yu SHEN, Zi-juan SUN, Shi-li SHANG, Jing-shan CHEN, Jun LI
2021, 42(1): 64-67. doi: 10.12259/j.issn.2095-610X.S20210136
Abstract(2654) HTML PDF(120) Cited By (6)
Abstract:
Objective To study the expression of HIF-1α in the serum of CKD patients, analyze the relationship between it and serum fibrosis index PⅢNP, and the clinical indicators of CKD patients, and explore the clinical application value of HIF-1α in CKD. M...
The Prevalence and Related Factors of Malocclusion on 3-to 5 Years-old Children with Primary Dentition in Kunming
Ru-jun ZHENG, Yue-xiao LI, Ya-lan YANG, Yu-mei HUANG, Shi-nan ZHANG, Yan-hong LI
2021, 42(1): 94-98. doi: 10.12259/j.issn.2095-610X.S20210142
Abstract(2764) HTML PDF(16) Cited By (10)
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Objective The aim of this study is to assess the malocclusion status, the risk factors and the parental awareness about deciduous malocclusion among 3-to-5-year-old children in Kunming. Methods Multistage stratified random sampling method was condu...
Clinical Analysis of 46 Children with Necrotizing Pneumonia
Song-tao BIN, Ming LI, Li TAN, Cheng-qing WU, Ji WANG, Xiao-qin HU
2021, 42(1): 124-129. doi: 10.12259/j.issn.2095-610X.S20210102
Abstract(3851) HTML PDF(22) Cited By (4)
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Objective To study the clinical characteristics, treatment and prognosis of necrotizing pneumonia (NP) in children. Method The clinical data of 46 patients with NP admitted to the Department of Respiratory Medicine of Kunming Children's Hospital fr...
Analysis of the Risk Factors Associated with Vascular Crisis after the Digits Replantation
Ze-zu MENG, Hang XIAN, Xiao-jin HOU, Shi-lei WEI, Ji MA, Rui ZHAO, Rui Cong
2021, 42(1): 130-134. doi: 10.12259/j.issn.2095-610X.S20210122
Abstract(3910) HTML PDF(18) Cited By (28)
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Objective To investigate the risk factors associated with the vascular crisis after the digits replantation and provide the evidence for the improvement of the replantation survival rate. Methods From Jan. 2016 to Dec. 2018, 26 cases(29 digits)suff...
The Application Value of CT Pulmonary Blood Flow Distribution in the Diagnosis of Pulmonary Embolism
Ge WANG, Ling-jun SHEN, Guo-hui LI, Yan YANG, Ji-kun ZHENG, Li-juan YUAN
2021, 42(1): 135-141. doi: 10.12259/j.issn.2095-610X.S20210128
Abstract(2532) HTML PDF(15) Cited By (2)
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Objective To explore the feasibility of CT pulmonary blood flow distribution in the diagnosis of pulmonary embolism. Methods Using the imaging efficiency of the imaging agent, the corresponding mapping mechanism was established by processing the im...
The Value of Echocardiography in Diagnosing Fetal Tetralogy of Fallot
Lin-kun TA, Yan-ling HUANG, Yong-ping LU
2021, 42(1): 142-146. doi: 10.12259/j.issn.2095-610X.S20210126
Abstract(3436) HTML PDF(19) Cited By (3)
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Objective To analyze the value of echocardiography in the diagnosis of fetal tetralogy of Fallot(TOF). Methods 558 pregnant women who underwent fetal echocardiography in the department of ultrasound of the Second People's Hospital of Yunnan Provinc...
Gene Screening and Result Analysis of 2 376 Cases of Thalassemia
Yun-juan WANG, Yan-liang ZHANG, Qiu-yue XU, Ying ZHAO, Zhao-wu HU, Yang SU
2021, 42(1): 68-71. doi: 10.12259/j.issn.2095-610X.S20210130
Abstract(2777) HTML PDF(24) Cited By (9)
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Objective To investigate the positive rate, gene mutation type and distribution characteristics of thalassemia gene screening patients in the First Affiliated Hospital of Kunming Medical University. Methods A retrospective analysis was made on 2376 c...
Efficacy Analysis of Levosimendan in the Treatment of Heart Failure Caused by Severe Coronary Heart Disease
Song MEI, Wen JIANG, Xiang-feng BAI, Wen-jie WANG, Dan HUANG, Wei CAO
2021, 42(1): 72-75. doi: 10.12259/j.issn.2095-610X.S20210121
Abstract(2839) HTML PDF(17) Cited By (14)
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Objective To analyze the efficacy and safety of levosimendan in patients with heart failure caused by severe coronary heart disease. Methods From January 2018 to January 2020, 40 patients who were hospitalized with the diffuse coronary artery disease...
Comparisons of the Effect of Balloon Dilatation and Reoperation on Benign Gallbladder Anastomosis
Shao-hua YANG, Yi-hui CHEN, Mao-lin HONG, Sheng HU, Xiao-wen ZHANG
2021, 42(1): 76-80. doi: 10.12259/j.issn.2095-610X.S20210135
Abstract(2823) HTML PDF(31) Cited By (3)
Abstract:
Objective To compare the effects of balloon dilatation and reoperation on benign biliary-enteric anastomotic stenosis. Methods From February 2009 to June 2019, 41 patients with benign biliary and intestinal anastomotic stenosis treated in the Second ...
Analysis on the Epidemiological Characteristics and Clinical Characteristics of 1 570 Hospitalized Children with Rotavirus Infection in Kunming Area
Jia-hui FANG, Cheng-jun DENG, Jin-tao DUAN, Su-qi XU, Ming-ying WANG
2021, 42(1): 81-84. doi: 10.12259/j.issn.2095-610X.S20210109
Abstract(3666) HTML PDF(25) Cited By (2)
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Objective To study the prevalence and different clinical manifestations of hospitalized children with rotavirus infection in Kunming. Methods The clinical data of 1570 cases of children hospitalized with rotavirus infection from 2014 to 2018 in Kunmi...
Changes of Coagulation Tetrad D Dimer and Pregnancy Outcome in Infertile Women before and after IVF Assisted Pregnancy
Jia-mei SONG, Jing-si CHEN, Yu-mei DENG, Zhi-jin HOU, Yu-shi MENG
2021, 42(1): 85-88. doi: 10.12259/j.issn.2095-610X.S20210124
Abstract(2764) HTML PDF(19) Cited By (8)
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Objective To explore the clinical significance of changes of coagulation tetrad and D-dimer(D-D)and pregnancy outcome in infertile women before and after IVF assisted pregnancy. Methods 115 cases of in vitro fertilization and embryo transfer were col...
A Clinical Study on the Use of Propofol Tenofovir in the Treatment of Chronic Hepatitis B
Zhi-rong ZHAO, Hai-wen LI, Ni-hong LU, Ling SHEN, Xiao-fei LI, Yong-rui YANG
2021, 42(1): 89-93. doi: 10.12259/j.issn.2095-610X.S20210141
Abstract(3688) HTML PDF(21) Cited By (19)
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Objective to observe the efficacy and safety in the clinic practice of Propofol Tenofavir Fumarate(TAF)as a treatment of Chronic Hepatitis B(CHB) Method A total of 180 Chronic-Hepatitis-B patients who had taken TDF antiviral therapy for 48 to 49 wee...
Effectiveness Comparison of Modular and Monoblock Femoral Prosthesis with Subtrochanteric Shortening Osteotomy in CroweType IV Developmental Dysplasia of the Hip
Zheng-gang LI, Xin-hua CUN, Xing TANG, Guo-liang WANG, Yi YANG, Jia-hui CHEN, Biao LI
2021, 42(1): 99-105. doi: 10.12259/j.issn.2095-610X.S20210115
Abstract(3394) HTML PDF(15) Cited By (4)
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Objective To compare the clinical efficacy of modular S-ROM femoral prosthesis and monoblock Wagner Cone femoral prosthesis used in total hip arthroplasty for the treatment of Crowe type IV developmental dysplasia of the hip. Methods Retrospective s...
Clinical Analysis of Vaginal Microecology in Patients with Polycystic Ovary Syndrome
Ting ZHAO, Hong-rong WANG, Zheng-jiao DONG, Mei-xiu GAO, Dong-yan REN, Tao YUAN
2021, 42(1): 106-109. doi: 10.12259/j.issn.2095-610X.S20210113
Abstract(3211) HTML PDF(25) Cited By (5)
Abstract:
Objective To compare the vaginal microecological results of newly diagnosed patients with polycystic ovary syndrome (PCOS) and healthy women, and to explore the etiology, diagnosis and treatment of PCOS patients. Methods 80 newly diagnosed PCOS patie...
Applications of Remote Coronary Artery Occlusion via Thrombus Suction Catheter in Patients with Acute Myocardial Infarction
Jing-qian LU, Feng YANG, Li-min YIN, Ping LI, Quan-shu ZHANG, Yong-quan JIA, Min CHEN, Ya-ping PAN
2021, 42(1): 110-114. doi: 10.12259/j.issn.2095-610X.S20210118
Abstract(3592) HTML PDF(19) Cited By (3)
Abstract:
Objective To the investigate the safety and efficacy of reverse use tirofiban and contrast agent through thrombus suction catheter after occlusion artery route in hyperthrombotic load patients with acute myocardial infarction. Methods From July 2018...
A Study of the Anatomical Structure of the Mandibular Canal in the Mandible by Cone-beam Computed Tomography
Jia-yun WANG, Juan-juan JI, Yun-hong LIN, Jian-zhong CHEN, Li-ming HE, Min HUANG, Xu-dong LI
2021, 42(1): 115-123. doi: 10.12259/j.issn.2095-610X.S20210104
Abstract(3606) HTML PDF(17) Cited By (4)
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Objective Cone-beam computed tomography(CBCT)was used to observe the anatomical structure of the mandibular canal in the mandible, providing theoretical basis for dental implants and alveolar surgery. Methods According to the inclusion and exclusion ...
The Correlation between Myocardial Enzymes and the Severity of Ketoacidosis in Children with Type 1 Diabetes
Juan-juan WANG, Yu-qing CHEN, Qian DENG, Jian GAO
2021, 42(1): 147-151. doi: 10.12259/j.issn.2095-610X.S20210129
Abstract(3307) HTML PDF(12) Cited By (7)
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Objective To investigate the correlation between myocardial enzymes and the severity of type 1 diabetic ketoacidosis in children. Methods From January 2016 to December 2019, thirty children with type 1 diabetes and DKA treated in Anhui Provincial Chi...
Effect of Laser Artificial Shrinkage on Pregnancy Outcome of Single Blastocysts Transfer with Different Developmental Days and Stages in the Frozen-thawed Cycles
Xiang LI, Yu-di LUO, Ju-guang ZHANG, Juan HE, Bo-wen LUO, Jun-jie ZHONG, Song-yuan TANG, Xiang-qian MENG
2021, 42(1): 152-156. doi: 10.12259/j.issn.2095-610X.S20210114
Abstract(2582) HTML PDF(15) Cited By (1)
Abstract:
Objective To investigate the effect of laser artificial shrinkage on the pregnancy outcome of single blastocysts transfer with different developmental days and stages in in the frozen-thawed cycles Methods The clinical data of 336 cases of frozen tha...
Research on the Relationship between Serum Homocysteine Level and Blood Lipids in Healthy People
Li DENG, Hong-li FANG, Guang-qiong CAO, Hui-fang GAO
2021, 42(1): 157-160. doi: 10.12259/j.issn.2095-610X.S20210107
Abstract(3344) HTML PDF(20) Cited By (4)
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Objective To explore the relationship between serum homocysteine(Hcy)and blood lipid in physical examination population and provide the evidence for the mechanism research between Hcy and lipid level. Methods 234 health examinees who came to the heal...
Reviews
Intestinal Barrier Damage Caused by Drug Dependence
Pu XIONG, Zun-yue ZHANG, Kun-hua WANG
2021, 42(1): 161-166. doi: 10.12259/j.issn.2095-610X.S20210131
Abstract(2554) HTML PDF(45) Cited By (1)
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Drug dependence is considered as a serious chronic recurrent encephalopathy. Long-term use of addictive substances will lead to the occurrence and development of related comorbidities including the central nervous system, respiratory system, circulat...
Nursing Forum
Effects of the Intensive Nursing Plan on Prevention of the Oral Mucositis Caused by Chemotherapy in Acute Leukemia
Ting-ting DUAN, Ya LV, Rui PAN, Li WANG, Ying TIAN
2021, 42(1): 167-172. doi: 10.12259/j.issn.2095-610X.S20210108
Abstract(3528) HTML PDF(25) Cited By (23)
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Objective To study the construction, the prevention and treatment effect of the intensive nursing plan of oral mucositis caused by chemotherapy in acute leukemia. Methods 100 patients newly diagnosed as acute leukemia chemotherapy in the Dept. of Hem...
Risk Factors and Nursing Strategies of PICC Catheter-related Infection in Tumor Patients
Jia LIU, Yin HE, Xin LIU
2021, 42(1): 173-176. doi: 10.12259/j.issn.2095-610X.S20210116
Abstract(3942) HTML PDF(31) Cited By (34)
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Objective To analyze the risk factors and countermeasures of PICC catheter-related infection in cancer patients. Methods From May 2019 to August 2020, 180 patients over 18 years old with PICC were enrolled and divided into non infection group(162 cas...