2023 Vol. 44, No. 2
2023, 44(2): 1-6.
doi: 10.12259/j.issn.2095-610X.S20230209
Abstract:
Objective To study the chemical compounds from the medicinal plants of Cremastra appendiculata and find its antitumor bioactive compounds. Methods The compounds were extracted by alcohol (95%) and isolated by column chromatography on silica gel and ...
2023, 44(2): 7-13.
doi: 10.12259/j.issn.2095-610X.S20230225
Abstract:
Objective To study the effect of TLR4/MyD88/NF- κB signal pathway on the hippocampus of methamphetamine (MA) dependent conditioned place preference (CPP) rats, and inhibition of Toll like receptor 4 (TLR4) by specific inhibitor TAK-242, thereby reduc...
2023, 44(2): 14-22.
doi: 10.12259/j.issn.2095-610X.S20230220
Abstract:
Objective To observe the effect of resveratrol on metastasis of nasopharyngeal carcinoma and explore its molecular mechanism. Methods (1)The inhibiting ability of resveratrol on nasopharyngeal carcinoma cells CNE2 was evaluated by CCK8 assay at diff...
2023, 44(2): 23-26.
doi: 10.12259/j.issn.2095-610X.S20230208
Abstract:
Objective To observe the effects of Caesalpinia Sappan L. ethanol extract, ethyl acetate, n-butanol and water extract on artificial demineralization enamel caries. Methods Bovine incisors were made into artificial demineralized enamel caries. The ef...
2023, 44(2): 27-32.
doi: 10.12259/j.issn.2095-610X.S20230205
Abstract:
Objective To investigate the intestinal flora in male uricase-deficient rats (Kunming-DY, KDY rats) compared with wild-type SD rats of the same sex and age. Methods 45-day-old male uricase-deficient rats were weighed, and their blood was collected ...
2023, 44(2): 33-39.
doi: 10.12259/j.issn.2095-610X.S20230226
Abstract:
Objective To investigate the effects of different dosages of gastrodin onTLR4/ MyD88 / NF-κB signal pathway in the hippocampus of methamphetamine (meth)dependence rats. Methods The conditioned place preference (CPP) model of meth was established, me...
2023, 44(2): 40-44.
doi: 10.12259/j.issn.2095-610X.S20230224
Abstract:
Objective To investigate the serovar distribution and epidemiological characteristics of Chlamydia trachomatis (CT)in female sex workers (FSWs) from Yunnan Province. Methods A survey of Chlamydia trachomatis in the genital tract was conducted in 202...
2023, 44(2): 45-51.
doi: 10.12259/j.issn.2095-610X.S20230201
Abstract:
Objectives To explore whether the expressions of miR-219-5p and / or SRY-related high-mobility-group box 5 (SOX5) in oral squamous cell carcinoma cells are differ from normal cells. We also aim to confirm the transcription regulation in SOX5 by miR-2...
2023, 44(2): 52-60.
doi: 10.12259/j.issn.2095-610X.S20230210
Abstract:
Objective To investigate the correlation between KRAS gene polymorphism and the occurrence and development of non-small cell lung cancer in Yunnan Han population. Methods In this study, 455 patients with non-small cell lung cancer and 391 healthy co...
2023, 44(2): 61-68.
doi: 10.12259/j.issn.2095-610X.S20230214
Abstract:
Objective To explore the optimal osteogenic ratio of Dental pulp stem cells (DPSC) with different concentrations in quantitative Bio-Oss bone powder. Methods The primary cells were isolated and cultured by adherent method. The surface markers of DP...
2023, 44(2): 69-74.
doi: 10.12259/j.issn.2095-610X.S20230207
Abstract:
Objective To study the application of NICS of different stages in the PGT treatment for patients with balanced translocation. Methods The parameters analyzed included testing results (tested successfully and rested failed) and CNVs results (normal a...
2023, 44(2): 75-87.
doi: 10.12259/j.issn.2095-610X.S20230218
Abstract:
Objective To explore the influencing factors of metastasis and prognosis in patients with primary gastric cancer (GC), and trying to find out the clinical indicators for early prediction of metastasis. Methods A retrospective study was conducted on...
2023, 44(2): 88-97.
doi: 10.12259/j.issn.2095-610X.S20230202
Abstract:
Objective To provide a practical basis for the field of elderly burn injury prevention and treatment by retrospectively analyzing the clinical data of elderly burn patients. Methods We retrospectively analyse the medical records of elderly burn pati...
2023, 44(2): 98-101.
doi: 10.12259/j.issn.2095-610X.S20230213
Abstract:
Objective To analyze the correlation between serum receptor activator of NF- κ B ligand (RANKL), osteoprotegerin (OPG), fibroblast growth factor 23 (FGF23) with renal function and calcium and phosphorus metabolism in patients with chronic kidney dise...
2023, 44(2): 102-107.
doi: 10.12259/j.issn.2095-610X.S20230219
Abstract:
Objective To establish a prediction model for lymph node metastasis and recurrence of thyroid cancer by analyzing patients’ lymph node FNA-Tg values, serum Tg values, and their ratios by binary logit regression. Methods 1. 64 patients with preoperat...
2023, 44(2): 108-112.
doi: 10.12259/j.issn.2095-610X.S20230217
Abstract:
Objective To investigate the application of three-dimensional speck tracking echocardiography in the evaluation of cardiotoxicity in trastuzumab treatment of breast cancer. Methods A total of 65 breast cancer patients treated with trastuzumab in the...
2023, 44(2): 113-119.
doi: 10.12259/j.issn.2095-610X.S20230211
Abstract:
Objective To explore the lipid metabolism levels and related factors in children with KD in different stages of disease, so as to provide more scientific and standardized long-term standardized treatment and health management for KD children in Yunna...
2023, 44(2): 120-124.
doi: 10.12259/j.issn.2095-610X.S20230221
Abstract:
Objective To explore the risk factors of ovarian necrosis caused by ovarian incarcerated indirect inguinal hernia in female infants. Methods This retrospective study enrolled 57 female infants of incarcerated inguinal hernia (referred to as incarcer...
2023, 44(2): 125-132.
doi: 10.12259/j.issn.2095-610X.S20230223
Abstract:
Objective In this study, the clinical, pathological and genetic data of PTC patients in The Third Affiliated Hospital of Kunming Medical University were collected, sorted out and statistically analyzed to explore the correlation between PTC gene muta...
2023, 44(2): 133-138.
doi: 10.12259/j.issn.2095-610X.S20230227
Abstract:
Objective To explore the diagnostic value of multispiral computed tomograpay (MSCT) combined with magnetic resonance imaging (MRI) in preoperative T staging of gastric cancer. Methods The preoperative imaging data of 57 patients with gastric cancer ...
2023, 44(2): 139-143.
doi: 10.12259/j.issn.2095-610X.S20230204
Abstract:
Objective To investigate the correlation between the expression of miR-192 in serum and left ventricular hypertrophy in patients with essential hypertension. Methods The clinical data of 187 patients with essential hypertension treated from June 201...
2023, 44(2): 144-149.
doi: 10.12259/j.issn.2095-610X.S20230203
Abstract:
Objective To investigate the application of high epidural combined general anesthesia in laparoscopic liver resection. Methods A total of 86 patients with laparoscopic hepatectomy in the Second People’s Hospital of Qujing City from March 2020 to Sep...
2023, 44(2): 150-155.
doi: 10.12259/j.issn.2095-610X.S20230206
Abstract:
Objective To explore the relationship between quantitative analysis of real-time ultrasound elastography and the prognosis of percutaneous transbiliary drainage (PTCD) in elderly patients with advanced malignant obstructive jaundice. Methods Retrosp...
2023, 44(2): 156-160.
doi: 10.12259/j.issn.2095-610X.S20230215
Abstract:
Objective To observe the effect of dolisetron mesylate combined with dexmedetomidine on plasma motilin levels and postoperative complications nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy. Methods One hundred and twenty ...
2023, 44(2): 161-165.
doi: 10.12259/j.issn.2095-610X.S20230216
Abstract:
Objective To explore the pathological classification of meningioma and the composition of patients, and obtain the epidemiological data of single-center meningioma of the Third Affiliated Hospital of Kunming Medical University, so as to provide the b...
2023, 44(2): 166-171.
doi: 10.12259/j.issn.2095-610X.S20230222
Abstract:
The main clinical feature of depression is marked and persistent low mood, and its high incidence and high disability have brought a heavy burden to individuals, families and society. Recent studies on neuroendocrine in patients with depression have ...
The main clinical feature of depression is marked and persistent low mood, and its high incidence and high disability have brought a heavy burden to individuals, families and society. Recent studies on neuroendocrine in patients with depression have ...
2023, 44(2): 172-176.
doi: 10.12259/j.issn.2095-610X.S20230228
Abstract:
Chronic obstructive pulmonary disease is a common, frequent and high mortality chronic disease of the respiratory system, while infection is the main cause of acute exacerbation of COPD; In recent years, serum amyloid A and heparin-binding protein ha...
Chronic obstructive pulmonary disease is a common, frequent and high mortality chronic disease of the respiratory system, while infection is the main cause of acute exacerbation of COPD; In recent years, serum amyloid A and heparin-binding protein ha...
2023, 44(2): 177-180.
doi: 10.12259/j.issn.2095-610X.S20230212
Abstract:
Objective To explore the effect of solution-focused nursing intervention on treatment compliance and quality of life of hepatitis C patients. Methods A total of 100 patients with chronic hepatitis C in the Liver disease Center of Kunming Third Peopl...