2023 Vol. 44, No. 2

Original Articles Basic of Medicine
Chemical Compounds Isolated from Cremastra Appendiculata and Their Bioactive Activity
Yupeng LI, Xinglong CHEN, Shengxing YUAN, Yajuan CHEN, Rongping ZHANG
2023, 44(2): 1-6. doi: 10.12259/j.issn.2095-610X.S20230209
Abstract(3362) HTML PDF(27) Cited By (5)
Abstract:
Objective To study the chemical compounds from the medicinal plants of Cremastra appendiculata and find its antitumor bioactive compounds. Methods The compounds were extracted by alcohol (95%) and isolated by column chromatography on silica gel and ...
Effect of TLR4/MyD88/NF- κB Signal Pathway on the Hippocampus of Methamphetamine-dependent CPP Rats
Yuan ZHANG, Tingna ZHU, Yuanyuan CAO, Pengliang LIU, Yihang WANG, Yamei WU, Lihua LI, Yongna ZHAO, Shijun HONG
2023, 44(2): 7-13. doi: 10.12259/j.issn.2095-610X.S20230225
Abstract(3075) HTML PDF(40) Cited By (1)
Abstract:
Objective To study the effect of TLR4/MyD88/NF- κB signal pathway on the hippocampus of methamphetamine (MA) dependent conditioned place preference (CPP) rats, and inhibition of Toll like receptor 4 (TLR4) by specific inhibitor TAK-242, thereby reduc...
Effect of Resveratrol on Metastasis of Nasopharyngeal Carcinoma and Its Related Mechanism
Huajie WU, Dezhen TU, Lei LI, Han QIAO, Guoping LI
2023, 44(2): 14-22. doi: 10.12259/j.issn.2095-610X.S20230220
Abstract(3818) HTML PDF(10) Cited By (1)
Abstract:
Objective To observe the effect of resveratrol on metastasis of nasopharyngeal carcinoma and explore its molecular mechanism. Methods (1)The inhibiting ability of resveratrol on nasopharyngeal carcinoma cells CNE2 was evaluated by CCK8 assay at diff...
Remineralization Effect of Caesalpinia Sappan L. on Artificial Demineralization of Enamel Caries
Rufang LI, Qiuyan LI, Xia CUI, Xia ZHAO, Limei WANG, hai LAN
2023, 44(2): 23-26. doi: 10.12259/j.issn.2095-610X.S20230208
Abstract(2757) HTML PDF(10) Cited By (2)
Abstract:
Objective To observe the effects of Caesalpinia Sappan L. ethanol extract, ethyl acetate, n-butanol and water extract on artificial demineralization enamel caries. Methods Bovine incisors were made into artificial demineralized enamel caries. The ef...
Intestinal Flora in Uricase-Deficient Rats
Dan LI, Xulian WAN, Lvyu LI, Yu YUN, Guangyun LUO, Weibing LIU, Gongfu LIN, Ning LI, Yongkun LI, Weigang DUAN
2023, 44(2): 27-32. doi: 10.12259/j.issn.2095-610X.S20230205
Abstract(5092) HTML PDF(11)
Abstract:
Objective To investigate the intestinal flora in male uricase-deficient rats (Kunming-DY, KDY rats) compared with wild-type SD rats of the same sex and age. Methods 45-day-old male uricase-deficient rats were weighed, and their blood was collected ...
Effects of Different Doses of Gastrodin on TLR4/MyD88/NF-κB Inflammatory Signal Pathway in Hippocampus of Methamphetamine Dependent CPP Rats
Tingna ZHU, Yuanyuan CAO, Yuan ZHANG, Pengliang LIU, Yihang WANG, Yamei WU, Lihua LI, Yongna ZHAO, Shijun HONG
2023, 44(2): 33-39. doi: 10.12259/j.issn.2095-610X.S20230226
Abstract(4214) HTML PDF(6) Cited By (3)
Abstract:
Objective To investigate the effects of different dosages of gastrodin onTLR4/ MyD88 / NF-κB signal pathway in the hippocampus of methamphetamine (meth)dependence rats. Methods The conditioned place preference (CPP) model of meth was established, me...
Analysis of Chlamydia Trachomatis Genotype among Female Sex Workers in Yunnan Province
Yuying ZHANG, Zhijun ZENG, Huichao CHEN, Xiaobin ZHANG, Zhaojun YANG, Jie DAI, Lijuan DONG, Wanyue ZHANG, Yanling MA, Min CHEN
2023, 44(2): 40-44. doi: 10.12259/j.issn.2095-610X.S20230224
Abstract(3197) HTML PDF(11)
Abstract:
Objective To investigate the serovar distribution and epidemiological characteristics of Chlamydia trachomatis (CT)in female sex workers (FSWs) from Yunnan Province. Methods A survey of Chlamydia trachomatis in the genital tract was conducted in 202...
Possible Roles of MiR-219-5p Targeting SOX5 in the Development of Oral Cancer
Ting ZHOU, Ying HE, Xiaohan DONG, Yanbin XIYANG, Bo CHEN, Jun TONG, Rui MAO
2023, 44(2): 45-51. doi: 10.12259/j.issn.2095-610X.S20230201
Abstract(3038) HTML PDF(13)
Abstract:
Objectives To explore whether the expressions of miR-219-5p and / or SRY-related high-mobility-group box 5 (SOX5) in oral squamous cell carcinoma cells are differ from normal cells. We also aim to confirm the transcription regulation in SOX5 by miR-2...
Correlation between KRAS Gene Polymorphism and Non-small Cell Lung Cancer in Yunnan Han Population
Yan LIANG, Lei WANG, Ming LEI, Benchao CHEN, Ping SUN, Shuai LI, Li LIU, Qianrong WANG, Manlin LIAO, Qianli MA
2023, 44(2): 52-60. doi: 10.12259/j.issn.2095-610X.S20230210
Abstract(3912) HTML PDF(30)
Abstract:
Objective To investigate the correlation between KRAS gene polymorphism and the occurrence and development of non-small cell lung cancer in Yunnan Han population. Methods In this study, 455 patients with non-small cell lung cancer and 391 healthy co...
Study on Osteogenic Ability of Dental Pulp Stem Cells at Different Concentrations
Shibing QIAN, Lingpeng ZHANG, Lingyun YIN, Changquan LI, Hu LI, Hongbin YU
2023, 44(2): 61-68. doi: 10.12259/j.issn.2095-610X.S20230214
Abstract(3054) HTML PDF(18)
Abstract:
Objective To explore the optimal osteogenic ratio of Dental pulp stem cells (DPSC) with different concentrations in quantitative Bio-Oss bone powder. Methods The primary cells were isolated and cultured by adherent method. The surface markers of DP...
Clinical Research
Application of NICS Testing at Different Stages in PGT Treatment of Patients with Reciprocal Translocation
Mingying LI, Minyao LI, Jiacong YAN, Mei TIAN, Yonggang LI
2023, 44(2): 69-74. doi: 10.12259/j.issn.2095-610X.S20230207
Abstract(3036) HTML PDF(11) Cited By (1)
Abstract:
Objective To study the application of NICS of different stages in the PGT treatment for patients with balanced translocation. Methods The parameters analyzed included testing results (tested successfully and rested failed) and CNVs results (normal a...
Correlation of Metastatic and Prognostic Factors in 318 Cases of Primary Gastric Cancer
Jiadai TANG, Jing YANG, Hongli SONG, Jiaojiao CHEN, Zhonghui MIAO, Lin XIE
2023, 44(2): 75-87. doi: 10.12259/j.issn.2095-610X.S20230218
Abstract(4028) HTML PDF(17) Cited By (4)
Abstract:
Objective To explore the influencing factors of metastasis and prognosis in patients with primary gastric cancer (GC), and trying to find out the clinical indicators for early prediction of metastasis. Methods A retrospective study was conducted on...
Analysis of Clinical Data of 471 Elderly Patients Hospitalized with Burns
Wei CHEN, Zichen ZHANG, Ruoyu WANG, He JIANG, Wende CAO, Yulan MIAO
2023, 44(2): 88-97. doi: 10.12259/j.issn.2095-610X.S20230202
Abstract(3563) HTML PDF(12) Cited By (5)
Abstract:
Objective To provide a practical basis for the field of elderly burn injury prevention and treatment by retrospectively analyzing the clinical data of elderly burn patients. Methods We retrospectively analyse the medical records of elderly burn pati...
Correlation between Serum RANKL,OPG,FGF23 and Renal Function and Calcium-phosphorus Metabolism in Patients with Chronic Renal Disease
Dexin MENG, Xiaoping ZHOU, Hu MENG, Hui HE, Lingli XIONG, Xiaomi MO
2023, 44(2): 98-101. doi: 10.12259/j.issn.2095-610X.S20230213
Abstract(2705) HTML PDF(10) Cited By (4)
Abstract:
Objective To analyze the correlation between serum receptor activator of NF- κ B ligand (RANKL), osteoprotegerin (OPG), fibroblast growth factor 23 (FGF23) with renal function and calcium and phosphorus metabolism in patients with chronic kidney dise...
Value of Binary Logit Regression Model Based on FNA-Tg and Serum Tg for Determining Lymph Node Metastasis or Recurrence of Thyroid Cancer
Lin WEI, Mei ZHU, Hailin ZHANG, Yuran FENG, Xi CHEN, Bailing WU, Yang YANG
2023, 44(2): 102-107. doi: 10.12259/j.issn.2095-610X.S20230219
Abstract(2923) HTML PDF(7) Cited By (1)
Abstract:
Objective To establish a prediction model for lymph node metastasis and recurrence of thyroid cancer by analyzing patients’ lymph node FNA-Tg values, serum Tg values, and their ratios by binary logit regression. Methods 1. 64 patients with preoperat...
Evaluation of Cardiotoxicity in Trastuzumab Treatment of Breast Cancer Using Three-dimensional Speckle Tracking Echocardiography
Wenjuan SONG, Xuejuan MA, Yue SUN, Ying GU, Yujia YE, Shumo LI, Fei GE, Liping LIU, Yue ZHAO, Yu WANG
2023, 44(2): 108-112. doi: 10.12259/j.issn.2095-610X.S20230217
Abstract(5197) HTML PDF(7) Cited By (3)
Abstract:
Objective To investigate the application of three-dimensional speck tracking echocardiography in the evaluation of cardiotoxicity in trastuzumab treatment of breast cancer. Methods A total of 65 breast cancer patients treated with trastuzumab in the...
Analysis of Lipid Metabolism Levels and Related Factors in Children with Kawasaki Disease in Different Courses
Xingzhu LIU, Yanfei YANG, Xing ZHANG, Liping GE, Feng WANG, Yuqin WU
2023, 44(2): 113-119. doi: 10.12259/j.issn.2095-610X.S20230211
Abstract(3853) HTML PDF(7) Cited By (1)
Abstract:
Objective To explore the lipid metabolism levels and related factors in children with KD in different stages of disease, so as to provide more scientific and standardized long-term standardized treatment and health management for KD children in Yunna...
Analysis of Risk Factors for Ovarian Necrosis with Ovarian Incarcerated Hernia
Hang YANG, Hao ZOU, Zhao NA, Li CHEN, Hui FANG
2023, 44(2): 120-124. doi: 10.12259/j.issn.2095-610X.S20230221
Abstract(3648) HTML PDF(9)
Abstract:
Objective To explore the risk factors of ovarian necrosis caused by ovarian incarcerated indirect inguinal hernia in female infants. Methods This retrospective study enrolled 57 female infants of incarcerated inguinal hernia (referred to as incarcer...
Correlation between Gene Mutation and Invasiveness in Papillary Thyroid Carcinoma
Ran ZHANG, Jie YANG, Enzi FENG, Xiaofeng YUAN, Qing WANG
2023, 44(2): 125-132. doi: 10.12259/j.issn.2095-610X.S20230223
Abstract(3442) HTML PDF(10) Cited By (2)
Abstract:
Objective In this study, the clinical, pathological and genetic data of PTC patients in The Third Affiliated Hospital of Kunming Medical University were collected, sorted out and statistically analyzed to explore the correlation between PTC gene muta...
Diagnostic Value of MSCT Combined With MRI in T Staging of Gastric Cancer
Huiqiong HE, Mengmei ZHANG, Ying YAN, Jing Lei, Yaying YANG, Kaipeng XIE
2023, 44(2): 133-138. doi: 10.12259/j.issn.2095-610X.S20230227
Abstract(3792) HTML PDF(5) Cited By (3)
Abstract:
Objective To explore the diagnostic value of multispiral computed tomograpay (MSCT) combined with magnetic resonance imaging (MRI) in preoperative T staging of gastric cancer. Methods The preoperative imaging data of 57 patients with gastric cancer ...
Correlation of the Expression of miR-192 in Serum Expression with Left Ventricular Hypertrophy in Patients with Essential Hypertension
Gaobo DU, Xiaofeng JIA, Qiang YU, Xiaojuan LI
2023, 44(2): 139-143. doi: 10.12259/j.issn.2095-610X.S20230204
Abstract(2816) HTML PDF(3)
Abstract:
Objective To investigate the correlation between the expression of miR-192 in serum and left ventricular hypertrophy in patients with essential hypertension. Methods The clinical data of 187 patients with essential hypertension treated from June 201...
Application of High Epidural Combined General Anesthesia in Laparoscopic Liver Resection
Weixing DING, Siyan WANG, Chen ZHOU, Jianyou TIAN, Yalin TAO, Ting LI, Huijuan PENG
2023, 44(2): 144-149. doi: 10.12259/j.issn.2095-610X.S20230203
Abstract(2894) HTML PDF(10)
Abstract:
Objective To investigate the application of high epidural combined general anesthesia in laparoscopic liver resection. Methods A total of 86 patients with laparoscopic hepatectomy in the Second People’s Hospital of Qujing City from March 2020 to Sep...
Quantitative Analysis of Real-time Ultrasound Elastography in Elderly Patients with Advanced Malignant Obstructive Jaundice in Assessing the Prognosis of PTCD
Hong LI
2023, 44(2): 150-155. doi: 10.12259/j.issn.2095-610X.S20230206
Abstract(3402) HTML PDF(6)
Abstract:
Objective To explore the relationship between quantitative analysis of real-time ultrasound elastography and the prognosis of percutaneous transbiliary drainage (PTCD) in elderly patients with advanced malignant obstructive jaundice. Methods Retrosp...
Effect of Dolisetron Mesylate Combined with Dexmedetomidine on Plasma Motilin and Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Rong QIN, Gang SU, Yu ZHANG, Wei YIN, zhen ZHAO
2023, 44(2): 156-160. doi: 10.12259/j.issn.2095-610X.S20230215
Abstract(3577) HTML PDF(7) Cited By (5)
Abstract:
Objective To observe the effect of dolisetron mesylate combined with dexmedetomidine on plasma motilin levels and postoperative complications nausea and vomiting in patients undergoing laparoscopic sleeve gastrectomy. Methods One hundred and twenty ...
Epidemiological Analysis of 771 Meningiomas
Qianlang REN, Gang BAI, Haonan WANG, Qilin LIU, Qianzheng SU
2023, 44(2): 161-165. doi: 10.12259/j.issn.2095-610X.S20230216
Abstract(3928) HTML PDF(16) Cited By (4)
Abstract:
Objective To explore the pathological classification of meningioma and the composition of patients, and obtain the epidemiological data of single-center meningioma of the Third Affiliated Hospital of Kunming Medical University, so as to provide the b...
Reviews
Research Overview of HPA Axis in Depression
Lei YU, Wenzhi WU, Yunqiao ZHANG, Xu YOU, Yong ZENG
2023, 44(2): 166-171. doi: 10.12259/j.issn.2095-610X.S20230222
Abstract(4199) HTML PDF(218) Cited By (26)
Abstract:
The main clinical feature of depression is marked and persistent low mood, and its high incidence and high disability have brought a heavy burden to individuals, families and society. Recent studies on neuroendocrine in patients with depression have ...
Advances in the study of heparin-binding protein and serum amyloid A in AECOPD co-infection of the lung
Wei MA, Meihua LI, Jing JIANG, Xingxu LIU, Lifen YANG, Li LI
2023, 44(2): 172-176. doi: 10.12259/j.issn.2095-610X.S20230228
Abstract(2811) HTML PDF(15) Cited By (11)
Abstract:
Chronic obstructive pulmonary disease is a common, frequent and high mortality chronic disease of the respiratory system, while infection is the main cause of acute exacerbation of COPD; In recent years, serum amyloid A and heparin-binding protein ha...
Nursing Forum
Application Value of Focused Solution Mode Nursing Intervention in Treatment Compliance and Quality of Life of Patients with Hepatitis C
Yanli MA, Cheng FENG, Liqing GUO, Xia GUO, Fengqiong ZHOU, Zhi-hui LIU, Yunhong MA
2023, 44(2): 177-180. doi: 10.12259/j.issn.2095-610X.S20230212
Abstract(3786) HTML PDF(9) Cited By (16)
Abstract:
Objective To explore the effect of solution-focused nursing intervention on treatment compliance and quality of life of hepatitis C patients. Methods A total of 100 patients with chronic hepatitis C in the Liver disease Center of Kunming Third Peopl...