2023 Vol. 44, No. 3

Original Articles Basic of Medicine
Chemical Compounds Isolated from Pleione maculata and Their Bioactive Activity
Yupeng LI, Xinglong CHEN, Shengxing YUAN, Yajuan CHEN, Rongping ZHANG
2023, 44(3): 1-6. doi: 10.12259/j.issn.2095-610X.S20230312
Abstract(4219) HTML PDF(41)
Abstract:
Objective To study the chemical compounds from the medicinal plants of Pleione maculata and find its bioactive compounds. Methods The compounds were extracted by alcohol (95%) and isolated by column chromatography on silica gel and Sephadex LH-20. T...
A Comparative Study of Rat Models of Intrauterine Adhesions Constructed in Different Ways
Linjuan YANG, Wenjiao JIN, Jinzhi LU, Zhenghua XIONG, Bin YAN, Xuesong HAN
2023, 44(3): 7-14. doi: 10.12259/j.issn.2095-610X.S20230322
Abstract(4158) HTML PDF(109)
Abstract:
Objective To find out the more stable rat models of intrauterine adhesions, so as to provide the basis for further investigation into the mechanism of intrauterine adhesions occurrence and exploration of novel treatments by constructing rat models of...
Metabolic Differences of Propranolol Enantiomers in Different Species of Liver Microsomes by HPLC-MS/MS
Canyu YANG, Kongchun SUN, Juan WANG, Huiping PU, Baochun SHEN
2023, 44(3): 15-21. doi: 10.12259/j.issn.2095-610X.S20230321
Abstract(3481) HTML PDF(42)
Abstract:
Objective To establish a method for the determination of R-(+) -propranolol and S-(-) -propranolol in the incubation system of liver microsomes by HPLC-MS/MS, and to compare the metabolic characteristics of R-(+) -propranolol and S-(-) -propranolol i...
Regulatory Role of PI3K/Akt Signaling Pathway in Hypertrophic Scar
Weimin LIU, Yiqun MA, Zhuo TIAN, Yang TANG
2023, 44(3): 22-27. doi: 10.12259/j.issn.2095-610X.S20230313
Abstract(3602) HTML PDF(47)
Abstract:
Objective To explore the regulatory role of PI3K/Akt signaling pathway in the hypertrophic scar. Methods The rabbit ear hypertrophic scar model was established and randomly divided into four groups, including normal rabbit ear skin group (A), hypert...
Effect and Mechanism of Twist1 Regulating Bmi1 on Invasion and Migration of Gallbladder Carcinoma Cells
Dongxing XU, Bo TANG, Guo ZHU, Xuefen LEI, Qiuhong WANG, Dong WEI
2023, 44(3): 28-33. doi: 10.12259/j.issn.2095-610X.S20230320
Abstract(3583) HTML PDF(13)
Abstract:
Objective To investigate the effect of Twist1 on invasion and metastasis of gallbladder carcinoma cells and the regulation of Bmi1, E-Cadherine andN-Cadherine. Methods Twist1 shRNA lentivirus vector was constructed to infect GBC-SD cells as the expe...
Effects of MMP-1 and MMP-7 on Pulmonary Hypertension in Rats
Ruyi FANG, Honglu LIU, Haiwen LI, Xi CHENG, Yangjun CHEN, Yushan LI, Yongrui YANG, Nihong LU
2023, 44(3): 34-43. doi: 10.12259/j.issn.2095-610X.S20230305
Abstract(2934) HTML PDF(22)
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Objective To explore the effects of MMP-1 and MMP-7 on pulmonary arterial hypertension (PAH). Methods The contents of MMPs (MMP-1, MMP-2, MMP-7, MMP-9, MMP-10, MMP-14) in the serum of PAH patients and healthy controls were detected and two MMPs were...
Comparison of Two Diagnosis Standards for Evaluating Hypertension in 18 Years Old Students in Yunnan China
Yunjuan YANG, Yuanyi ZHA, Tunan LI
2023, 44(3): 44-48. doi: 10.12259/j.issn.2095-610X.S20230324
Abstract(3638) HTML PDF(17)
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Objective By taking the “Guidelines for the Prevention and Treatment of Hypertension in China” (2022 revised edition) as the gold standard, and “Clinical Practice Guidelines for Hypertension in China” (November 2022 edition) as the test standard, to ...
Comparison of Two Induction Methods of Temporo-mandibular Joint Osteoarthritis in Rat Models
Wenli HUANGFU, Yao HUANG, Bo LIU, Changhai LV, Juan LIU, Zichao DAI
2023, 44(3): 49-53. doi: 10.12259/j.issn.2095-610X.S20230308
Abstract(4137) HTML PDF(63)
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Objective To establish TMJ-OA rat models by occlusal disorder and forced open mouth, compare two TMJ-OA induction methods and assess their applicability by pathological changes in the cartilage, subchondral bone. Methods Twenty-one 8-week-old Spragu...
Clinical Research
Clinicopathological Features and Prognosis of Mucinous Breast Carcinoma
Ting GAO, Sheng HUANG, Rong GUO, Dedian CHEN
2023, 44(3): 54-60. doi: 10.12259/j.issn.2095-610X.S20230306
Abstract(4267) HTML PDF(34)
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Objective To investigate the clinicopathological characteristics of mucinous breast carcinoma (MuBC) and its relationship with prognosis, so as to provide reference for patients to make a personalized treatment plan. Methods The clinical and patholog...
Distribution and Drug Resistance Analysis of Bacteria in Sterile Body Fluids in Yunnan from 2017 to 2021
Jie LI, Yuan HE, Chunyan WU, Bin SHAN, Rui ZHENG, Zhifu GUAN, Baojun REN, Chunxia SHI, Youquan ZHOU, Hanyu LIU, Mi ZHANG, Yanming KANG, Guibo SONG
2023, 44(3): 61-67. doi: 10.12259/j.issn.2095-610X.S20230309
Abstract(3149) HTML PDF(12)
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Objective To explore the bacterial distribution and drug resistance of sterile body fluid specimens (excluding blood) in nine tertiary general hospitals in Yunnan Province from 2017-2021, and to provide a reference basis for the rational clinical use...
Correlation Analysis of Chronic Diseases and Physical Labor Intensity among the Rural Elderly in Two Counties of Yunnan Province
Yan DONG, Wenwen LI, Wenlong CUI, Jie LIU, Weihong BI
2023, 44(3): 68-73. doi: 10.12259/j.issn.2095-610X.S20230303
Abstract(4260) HTML PDF(17)
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Objective To understand the prevalence of chronic diseases among the rural elderly in Yulong County and Fumin County of Yunnan Province, explore and analyze the relationship between elderly chronic diseases and physical labor intensity, and provide t...
Application of Different Sealing Materials and Adhedive Systems in Pit and Fissure Sealing of Deciduous Molars
Yu LUO, Shinan ZHANG, Ni ZHOU, Changhai LYU
2023, 44(3): 74-80. doi: 10.12259/j.issn.2095-610X.S20230314
Abstract(3997) HTML PDF(12)
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Objective To compare the operation time, acceptability and sealing effect of resin-based sealant and resin-reinforced glass ionomer combined with certain adhesive systems applied to seal deciduous molar teeth, so as to provide a more appropriate oral...
Analysis of HPV Detection in 18 449 Hospital Patients in Kunming and HPV Vaccination Recommendations
Jiawei DING, Jia WANG, Shu YANG, Sulian CHEN, Jing LI
2023, 44(3): 81-86. doi: 10.12259/j.issn.2095-610X.S20230302
Abstract(3755) HTML PDF(18)
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Objective To analyze the detection and subtype distribution characteristics of human papillomavirus (HPV) in the genital tract of the first outpatient in the hospital, and to provide reference for the prevention and vaccination of HPV in the region. ...
Clinical Significance of a Marker of Thrombin Activity-fibrin Monomer after Surgery
Jinxi YUE, Linjun WAN, Ruiling ZHANG, Xiaoran ZHANG, Ouya LIU, Xiaofan YU, Qingqing HUANG, Zongfang REN
2023, 44(3): 87-91. doi: 10.12259/j.issn.2095-610X.S20230325
Abstract(3137) HTML PDF(39)
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Objective To investigate the clinical significance and monitoring value of fibrin monomer (FM)after surgery. Methods A total of 93 patients after surgery admitted to the Department of Critical Care Medicine, the Second Affiliated Hospital of Kunming...
Morphological Study of Adult Infrapatellar Fat Pad Thickness Measured by MRI
Sixue PAN, Jiangchuan WU, Guangxiong HE, Junyi XIANG, Jiliang XIA, Chaoyu BAO
2023, 44(3): 92-96. doi: 10.12259/j.issn.2095-610X.S20230315
Abstract(4422) HTML PDF(12)
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Objective To investigate the feasibility of measuring the thickness of adult subpatellar fat pad based on MRI and the correlation between the thickness of adult subpatellar fat pad and sex, age, weight and height, to provide the basis for keeping the...
Value of cMyBP-C in Clinical Diagnosis of Acute Myocardial Infarction
Xiaodong ZHU, Yanlong LIU, Xu ZHOU, Hailong DAI, Xiaolong YIN
2023, 44(3): 97-102. doi: 10.12259/j.issn.2095-610X.S20230328
Abstract(3826) HTML PDF(29)
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Objective To investigate the potential of cardiac myosin binding protein-C (cMyBP-C) as a novel marker of myocardial infarction by detecting the concentration of cardiac myosin binding protein-C (cMyBP-C) in venous blood of patients with acute myocar...
Clinical Effect of Duodenum-Preserving Pancreaticohead Resection And Pancreaticojejunostomy for Pancreatic Head Calculi
Kun SU, Lianmin WANG, Chaoyu MA, Dongfang LIU, Shijun LI, Xianghui WANG, Jinfan LI, Ling ZHANG, Bo LI, Tao WU
2023, 44(3): 103-112. doi: 10.12259/j.issn.2095-610X.S20230316
Abstract(3320) HTML PDF(18)
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Objective To explore the difference between duodenum-preserving pancreatic head resection (DPPHR) and pancreatic-preserving pancreatic duct jejunostomy (Partington operation) in the treatment of pancreatic head calculus, and evaluate the advantages a...
Analysis on the Application of Optical Coherence Tomographic and Quantitative Flow Ratio in Intermediate In-stent Restenosis Lesions
Ziwei ZHANG, Xiaojuan PAN, Jihong ZOU, Jun YANG, Jialin ZHENG, Jie BAI, Jiong TANG, Xurui ZHANG, Feng QI
2023, 44(3): 113-119. doi: 10.12259/j.issn.2095-610X.S20230327
Abstract(2616) HTML PDF(8)
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Objective To observe the effect of combined guidance of optical coherence tomographic (OCT) and quantitative flow ratio (QFR) in patients with In-stent restenosis (ISR) of intermediate severity. Methods Patients with intermediate ISR lesions were pe...
Effect of Childhood Abuse on Non-suicidal Self-injury in Adolescents with First-episode Depression
Deng'ai DUAN, Yonghui ZHANG, Wei WANG, Xinju LIAO, Zhixiong ZHANG
2023, 44(3): 120-124. doi: 10.12259/j.issn.2095-610X.S20230304
Abstract(5356) HTML PDF(24)
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Objective To explore the effects of childhood abuse on Non-suicidal Self-injury(NSSI) in patients with first-episode adolescent depression in the Yunnan Provincial Psychiatric Hospital. Methods A total of 136 depressed patients aged 12 to 18 years h...
Clinical Observation of HEOS in the Treatment of Moderate and Severe Intrauterine Adhesions
Chaoqun WANG, Liyan MENG, Junli GAO, Rongxia HUANG, Jie NIU, Jian CHEN
2023, 44(3): 125-130. doi: 10.12259/j.issn.2095-610X.S20230317
Abstract(3400) HTML PDF(9)
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Objective To observe the clinical efficacy and pregnancy outcome of hysteroscopic cold knife system in patients with moderate and severe intrauterine adhesions who planned to undergo assisted reproduction. Methods Patients with moderate and severe ...
Relationship between Bile Duct Uneven Dilation and Postoperative Pancreatitis after ERCP
Yanyang LI, Kejia LI, Ang LIU, Zhihong ZHANG, Xueyuan DANG, Guohui SHAO, Zhitian SHI, Lin WANG, Dong WEI, Jiayun GE
2023, 44(3): 131-137. doi: 10.12259/j.issn.2095-610X.S20230311
Abstract(3728) HTML PDF(16)
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Objective To investigate the relationship between bile duct uneven dilatation and postoperative pancreatitis after ERCP. Methods A total of 247 cases of ERCP+EST + ENBD due to bile duct stone were performed in the Second Affiliated Hospital of Kunmi...
Clinical Application Evaluation and Standard,Reasonable Use of Fat Emulsion,Amino Acids (17) and Glucose (11%) Injection
Xiuhua WANG, Zeran HE, Zhihong LI, Huiling WANG, Hongyan SU
2023, 44(3): 138-142. doi: 10.12259/j.issn.2095-610X.S20230318
Abstract(3646) HTML PDF(52)
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Objective To evaluate the clinical application of fat emulsion amino acid (17) glucose (11%) injection (trade name: Calvin) to improve the standardization and rationality of it’s clinical application. Methods Using the hospital information system (H...
Reviews
Research Progress on Gene Related to Suicide in Major Depressive Disorder:A Review
Zhaosong CHU, Xin WANG, Mengxin HE, Xiufeng XU, Na WANG, Zonglin SHEN
2023, 44(3): 143-148. doi: 10.12259/j.issn.2095-610X.S20230301
Abstract(4063) HTML PDF(61)
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Suicide is a major global public health concern and is one of the leading causes of death worldwide, causing enormous socioeconomic losses and psychological damage to human beings. Major depressive disorder is the leading cause of death of suicide, a...
Research Progress of ACSM Protein Family in Tumor
Chenglu HE, Ya LI, Min ZHU, Min ZHONG, Yong DUAN
2023, 44(3): 149-154. doi: 10.12259/j.issn.2095-610X.S20230307
Abstract(4128) HTML PDF(57)
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Acyl-CoA Synthetase Medium Chains(ACSMs) are enzymes that can activate C6~C10 fatty acids and participate in the synthesis and decomposition of medium chain fatty acids. They are of great significance for cell survival. When tumor occurs, due to the ...
Application of Bone Marrow Mesenchymal Stem Cells in Stomatology
Rongyu YANG, Fei SONG, Hao HUANG, Kaiwen DUAN, Yingying XIANG
2023, 44(3): 155-159. doi: 10.12259/j.issn.2095-610X.S20230323
Abstract(3461) HTML PDF(18)
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In the maxillofacial region, tissue defects caused by tumors, trauma, congenital or acquired acute can cause serious damage to the patient’s appearance, normal physiological function and mental health, and overall quality of life of the patient. It i...
Nursing Forum
Investigation on the Needs of Caregivers for Eating Knowledge and Skills in Patients with Dysphagia after Stroke
Siya XIA, Mingying YANG, Yuqin LIU, Tingrui MENG, Linrong LI, Yiqi HU, Yao XIAO
2023, 44(3): 160-166. doi: 10.12259/j.issn.2095-610X.S20230319
Abstract(4765) HTML PDF(22)
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Objective To understand the status quo and correlation of eating knowledge and skills needs of caregivers of patients with dysphagia after stroke, and to provide reference for medical workers to carry out targeted nursing training for caregivers. Me...
Application of White Noise in Neonatal Peripheral Venipuncture Pain
Tuan LI, Yu’e ZHOU, Yue LI
2023, 44(3): 167-171. doi: 10.12259/j.issn.2095-610X.S20230310
Abstract(4424) HTML PDF(13)
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Objective To analyze the effect of white noise intervention in neonatal peripheral venipuncture pain. Methods A total of 135 hospitalized neonates from September 2022 to November 2022 in the Pediatric Newborn Intensive Care Unit of a hospital in Yun...
Effect of Rehabilitation Training Based on Mechanics Concept Combined with Ilizarov Technical Orthopedics on Knee Joint Stability and Lower Limb Weight Bearing in Elderly Patients with Knee Osteoarthritis
Xue ZHANG, Weiwei CHEN, Cuihua LI, Haitao CAO
2023, 44(3): 172-178. doi: 10.12259/j.issn.2095-610X.S20230326
Abstract(3592) HTML PDF(17)
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Objective To investigate the effect of rehabilitation training based on mechanical concepts combined with Ilizarov technical orthopedics on knee joint function, stability and lower limb weight bearing in elderly patients with knee osteoarthritis. Me...