2021 Vol. 42, No. 10

Original Articles Basic of Medicine
Effects of Scutellarin on Expressions of PKC and TNF-α in OX-LDL Injured RAW264.7 Cells in vitro
Li ZHANG, Dan YU, Yu-ting WANG, Zhi-mei GOU, Ren-hua YANG, Bo HE, Zhi-qiang SHEN, Wen-ying CHAI, Peng CHEN
2021, 42(10): 1-7. doi: 10.12259/j.issn.2095-610X.S20211040
Abstract(3450) HTML PDF(111)
Abstract:
Objectives To investigate the effects of scutellarin on lipid phagocytosis and the regulation of PKC, and TNF-α expressions in low density lipoprotein (OX-LDL) injured RAW264.7 cells. Methods Murine RAW264.7 macrophages was cultured in vitro. Then, ...
Establishment of Rat Myoblast Atrophy Model Induced by Ang Ⅱ
Wei-jie SU, Mei-sha ZHANG, Jia-ning LI, Ying LIU, Ding-jie XU, Hong CHANG
2021, 42(10): 8-13. doi: 10.12259/j.issn.2095-610X.S20211026
Abstract(4017) HTML PDF(38)
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Objective To provide a model basis for further study of heart failure complicated with sarcopenia, a rat myoblast (L6) atrophy model induced by Ang Ⅱ was established. Methods 2% horse serum was used to induce differentiation of L6 cells. The time of...
Effects of Silencing RND3 Expression on the Inflammatory Response and Apoptosis of Hippocampal Neurons Injured by Oxygen Glucose Deprivation/Reoxygenation
Jun-jie LI, Hai-yan JIANG, Wen-ya BAI, Si-ying HUO, Zhi-sheng SUN, Jian-lin SHAO
2021, 42(10): 14-21. doi: 10.12259/j.issn.2095-610X.S20211012
Abstract(3519) HTML PDF(16)
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Objective To investigate the protective effect of silencing Rho family GTPase3 (RND3) expression against oxygen glucose deprivation/reoxygenation (OGD/R) injury in hippocampal neurons via inhibiting inflammation and apoptosis and its mechanism. Meth...
Association of the miR-149,miR-219 and miR-let-7 Polymorphisms with the Occurrence and Development of Non-small Cell Lung Cancer in a Chinese Han Population in Yunnan Province
Jia YANG, Ya-xian LI, Ying-ying WANG, Lin XIAO, Chuan-yin LI, Fang TAN, Qian-li MA, Shu-yuan LIU
2021, 42(10): 22-28. doi: 10.12259/j.issn.2095-610X.S20211037
Abstract(4274) HTML PDF(27)
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Objectives To investigate the relationship between mircoRNA gene polymorphisms and the occurrence and development of non-small cell lung cancer in Yunnan Han population. Methods A total of 415 lung cancer patients of non-small cell lung cancer and 4...
Mechanism of miR-373 on Behaviors of Depression-mice via P2X7R
Xiao-yun WANG, Qiao-yun WANG, Ming-hua GU, Yu DING, Yu-wen GUANG, Ji-lan ZHANG
2021, 42(10): 29-37. doi: 10.12259/j.issn.2095-610X.S20211030
Abstract(4111) HTML PDF(24)
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Objective To explore the effect of miR-373 on depression-like behavior, microglia activation and pyrolysis in depression mice. Methods We Used chronic unpredictable stress to establish depression mice model. Sucrose preference, forced swimming, tail ...
Analysis of Trend in Prevalence of Hypertension and Its Relationship with Different Obesity Indices among Rural Adults in Fumin County of Yunnan Province
Lian-ju HE, Chun-mei ZUO, Lan LIU, Wen-long CUI, Jin-bo LI, Yi MO, Lu-ming FAN, Le CAI
2021, 42(10): 38-44. doi: 10.12259/j.issn.2095-610X.S20211008
Abstract(5122) HTML PDF(17)
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Objective To analyze the trend of hypertension prevalence and its relationship with different obesity indices among rural adults in Fumin county of Yunnan province. Methods A repeated cross-sectional surveys was employed. A total of 2544 individuals...
Knowledge and Behavior of Antibiotics from the Perspective of One Heath among Senior University Students in Kunming
Shu-qi CHEN, Peng ZHAO, Ge-fen YIN, Xia XIAO, Yan LI
2021, 42(10): 45-50. doi: 10.12259/j.issn.2095-610X.S20211003
Abstract(2488) HTML PDF(22)
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Objective To explore the multi-level knowledge and behavior related antibiotics from the perspective of One Heath among senior undergraduates who have received pharmacology professional knowledge or training in Kunming. Methods From February, 2020 t...
Clinical Research
Clinical Characteristics of Acute Ischemic Stroke Based on Multiple Imaging Evaluation
Zhi-peng YU, Ai-ran DONG, Jing ZHANG, Fang WU, Ming-jie GAO, Jian CHEN, Hong CHANG, Li-yong WU
2021, 42(10): 51-60. doi: 10.12259/j.issn.2095-610X.S20211039
Abstract(3562) HTML PDF(17)
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Objective To analyze the clinical characteristics of acute ischemic stroke combined with multiple imaging assessment. Methods Multiple images were combined to evaluate the incidence, arterial pathological changes, the responsible vessels for infarc...
Expression and Significance of Plasma miR-1181 in Patients with Type 2 Diabetes Mellitus
Jing-mei LUO, Can-hui LI, Lan LI, Jie LIN, Jin-rong ZHANG, Li-hua ZHANG
2021, 42(10): 61-67. doi: 10.12259/j.issn.2095-610X.S20211019
Abstract(3014) HTML PDF(18)
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Objective To verify that miRNA can be used as biomarkers to predict the occurrence and development of diabetes mellitus (DM), and to explore the expression of miR-1181 in patients with type 2 diabetes mellitus (Type 2 Diabetes Mellitus). Methods Agi...
Clinical Effect of Dexmedetomidine and Dexamethasone as Adjuvants for Brachial Plexus Block
Zhao-sen FENG, Yu FANG, Ding-qin OU, Yi-han YANG, Zhi-yao WANG, Jie HUANG
2021, 42(10): 68-75. doi: 10.12259/j.issn.2095-610X.S20211005
Abstract(3712) HTML PDF(19)
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Objective To investigate the effect of adding dexmedetomidine (DEX) or dexamethasone (DXM) on the effect of interscalene brachial plexus block. Methods Fifty patients who underwent ultrasound-guided interscalene brachial plexus block were randomly se...
Correlation between Cerebral Perfusion and Retinal Oxygenation Response of Diabetic Retinopathy in Type 2 Diabetes Mellitus
Yu-xing XIONG, Jun TANG, Ru-yun LIN, Jia-min NIE, Min-jie ZHOU, Ju-wei SHAO
2021, 42(10): 76-83. doi: 10.12259/j.issn.2095-610X.S20211046
Abstract(4268) HTML PDF(11)
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Objective To study MR cerebral perfusion and the retinal oxygenation response in patients with different stages of diabetic retinopathy without hypertension and normal control group, and to analyze the correlation between different cerebral perfusion...
Study on the Morphology and Function of a Single Parathyroid Gland in situ by Endoscopy and Parathyroid Hormone Determination in Drainage Fluid
Yun-hai MA, Jun QIAN, Shu-ling LI, Ting-ting YAN, Ruo-chuan Cheng
2021, 42(10): 84-91. doi: 10.12259/j.issn.2095-610X.S20211045
Abstract(2562) HTML PDF(11)
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Objective To explore the changing rule of morphology and function single parathyroid gland in situ, so as to provide a theoretical basis for the survival, function and prognosis of parathyroid glands with different blood supply types. Methods Forty-t...
Comparison of Six Methods of Ultrasound-guided Fine-needle Aspiration Biopsy of Thyroid Nodules
Lin WEI, Yu-ran FENG, Hui YUAN, Ke-yu ZHOU, Yi ZHAO, Jun QIAN, Mei ZHU
2021, 42(10): 92-98. doi: 10.12259/j.issn.2095-610X.S20211044
Abstract(3801) HTML PDF(13)
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Objective To compare the accuracy of six operative methods of ultrasound-guided fine-needle aspiration biopsy of thyroid nodules and to share the experience of the operation. Methods The data of 1903 patients who underwent thyroid surgery, preoperati...
Clinical Application of Xenogenic Acellular (bovine) Dermal Matrix with Autologous Bone Powder Implantation in Open Mastoidectomy
Li -zhu WANG, Shu-ling LI, Biao RUAN
2021, 42(10): 99-105. doi: 10.12259/j.issn.2095-610X.S20211029
Abstract(3597) HTML PDF(10)
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Objective To investigate the application of xenogenic acellular (bovine) dermal matrix (ADM) combined with autologous bone powder implantation in open mastoidectomy, and investigate the effect on ear drying, epithelization, survival of autogenous bon...
Comparison of Two Surgical Managements for the Delayed Ankles Fracture Combined with Distal Tibiofibular Syndesmosis Injuries
Lu-ping LIU, Lan-ran ZHU, Wei ZHANG, Lei-jie CHEN, Chao-ran WANG, Jing-wu LIAO
2021, 42(10): 106-111. doi: 10.12259/j.issn.2095-610X.S20211017
Abstract(3400) HTML PDF(12)
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Objective To investigate the effect of surgical treatments for delayed ankles fracture combined with distal tibiofibular syndesmosis injuries (AFTSI). Methods A retrospective study the operative effects of 38 cases of delayed AFTSI treated with open...
MiRNA-145 Negatively Regulates OCT4 Expression in Endometriosis
Lu WU, Qing-hua ZHAO, Shao-yan YANG, You-fang HOU, Su-xian ZHANG
2021, 42(10): 112-116. doi: 10.12259/j.issn.2095-610X.S20211032
Abstract(4328) HTML PDF(10)
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Objective To study the expression and clinical significance of miRNA-145 and OCT4 in endometriosis. Methods From August 2018 to August 2020, 30 EMs patients (experimental group) and 30 patients with infertility caused by fallopian tube factors (cont...
Effect of UE Video Laryngoscope and Fiberoptic Bronchoscope for Awake Orotracheal Intubation
Dong WANG, Ying TAN, Jun WANG, Min GAO
2021, 42(10): 117-120. doi: 10.12259/j.issn.2095-610X.S20211027
Abstract(2843) HTML PDF(15)
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Objective To observe the effect on two kinds of tracheal intubation guiding equipment (video laryngoscope andfiberoptic bronchoscope)for awake orotracheal intubation. Methods Sixty patients with difficult airway requiring conscious intubation were r...
Curative Effect of Combined Hemihepatectomy and Perihilar Hepatectomy in Treatment of Hilar Cholangiocarcinoma
Liu-zheng LI, Shun LU, Shi-rong ZHANG, Lei-sheng XU, Hai-rong ZHAO, Jia-wei FENG, Xue-chan GAO, Tong WU
2021, 42(10): 121-126. doi: 10.12259/j.issn.2095-610X.S20211014
Abstract(3833) HTML PDF(11)
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Objective To summarize the curative effect of different surgical resection methods for hilar cholangiocarcinoma (HCCA). Methods The clinical data of 52 patients with HCCA who underwent surgery in Lincang people's Hospital from January 2015 to Decemb...
MRI Diagnosis of Nodular Breast Lesions
Jian-cheng HAO, li-juan SUN, jin-gang HAO
2021, 42(10): 127-131. doi: 10.12259/j.issn.2095-610X.S20211007
Abstract(4174) HTML PDF(14)
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objective To investigate the value of MRI diagnosis of nodular breast benign and malignant lesions. Methods Retrospective analysis of 71 patients with nodular breast disease confirmed by pathology in our hospital, Perform MRI multi-parameter imaging...
Changes and Clinical Significance of Plasma sTREM-1,sFLT-1 and SOD Levels in Patients with Severe Pneumonia
Zheng-gao FU, Yu CHEN, Yong LIANG, Jun-xu XU, Ting-shi WU, Jin-xiang HAO
2021, 42(10): 132-138. doi: 10.12259/j.issn.2095-610X.S20211006
Abstract(3391) HTML PDF(102)
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Objective To investigate the changes and clinical significance of plasma levels of soluble myeloid cell trigger receptor-1 (sTREM-1), soluble Fms-like tyrosine kinase receptor-1 (sFLT-1) and superoxide dismutase (SOD) in patients with severe pneumoni...
Clinical Investigation of Vitamin D and Calcium Supplement’ Effect on the Occurrence of Cardiovascular and Cerebrovascular Diseases in POP Patients
Ling-ling YAN, Zhi-hong QIAN, Yue NI, Huang WU
2021, 42(10): 139-144. doi: 10.12259/j.issn.2095-610X.S20211036
Abstract(3609) HTML PDF(11)
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Objective To investigate the vitamin D (VD) and calcium supplement’effect on the occurrence of cardiovascular and cerebrovascular diseases in Primary osteoporosis (POP) patients accompanied with hypertension or coronary heart disease. Methods From O...
Changes and Abnormal Patterns of Coagulation Indicators in Patients with Lung Adenocarcinoma and Tuberculosis Pleural Effusion
Yan-fen MA, Jian HU, Ning ZHANG, Qian WU, Xiao-qin WANG
2021, 42(10): 145-150. doi: 10.12259/j.issn.2095-610X.S20211021
Abstract(5170) HTML PDF(9)
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Objective To assesse the changes and abnormal patterns of coagulation indicators in distinguishing malignant pleural effusion of lung adenocarcinoma (AD-MPE) and tuberculous pleural effusion (TPE) and acquire the optimal diagnostic model. Methods Pa...
Efficacy and Prognosis of Levetiracetam Injection in the Treatment of Convulsive Status Epilepsy
Hao-hao WU, Jun-su YANG, Bao-gang HUANG, Shao-yong GUAN, Yan ZHENG, Hui-juan FAN
2021, 42(10): 151-156. doi: 10.12259/j.issn.2095-610X.S20211031
Abstract(3794) HTML PDF(18)
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Objective To analyze the control effect and prognosis of Levetiracetam injection on convulsive epileptic status (CSE), in order to promote its clinical application. Methods A total of 80 CSE patients were enrolled in the Department of Neurology inte...
Diagnostic Effect and Imaging Characteristics of High Frequency Ultrasound in Limb Skeletal Muscle Injury
Yan LIANG, Jian-bo GAO, Jun-yan MA, Hao YANG
2021, 42(10): 157-161. doi: 10.12259/j.issn.2095-610X.S20211015
Abstract(4937) HTML PDF(23)
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Objective To investigate the diagnostic effect and imaging characteristics of high-frequency ultrasound in skeletal muscle injury of limbs. Methods Seventy-two patients with limb musculoskeletal injury after major exercise admitted to Yunnan St.John'...
Therapeutic Effect and Prognosis of Optimal Arterial Compliant Pulmonary Retraction in Patients with Severe Stroke Complicated with Atelectasis or Respiratory Distress Syndrome
Ling-jun SHEN, Ge WANG, Li-juan YUAN
2021, 42(10): 162-166. doi: 10.12259/j.issn.2095-610X.S20211025
Abstract(3173) HTML PDF(13)
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Objective To compare the clinical efficacy and prognosis of patients with severe stroke complicated with atelectasis or respiratory distress syndrome after different pulmonary reopening treatments. Methods We made a prospective analysis of 96 patien...
Reviews
The Function and Significance of Temporary Occlusal Pad in Patients with Severe Abrasion
Lian LI, Fei SONG, Rong-yu YANG, Ying-ying XIANG
2021, 42(10): 167-171. doi: 10.12259/j.issn.2095-610X.S20211013
Abstract(2653) HTML PDF(19)
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Severe dentition is a kind of disease caused by loss of physiologic median jaw position, which is often seen in middle-aged and elderlypatients. Occlusal reconstruction refers to the reconstruction and re-establishment of the occlusal state of dentit...
Teaching Research
Exploration and Application of Standardized Training for Cardiovascular Practitioner in Chest Pain Center
Zhi-hua YANG, Xing LIANG
2021, 42(10): 172-177. doi: 10.12259/j.issn.2095-610X.S20211043
Abstract(3442) HTML PDF(13)
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Objective To explore the application effect of Chest Pain Center in standardized training for cardiovascular practitioner. Methods Fifty-two students for cardiovascular practice were selected from 2020 July to September, they were randomly divided ...
Nursing Forum
Construction and Effect Evaluation of Case Management Model in Prevention of High Risk Pressure Injury in Elderly Inpatients
Jun DA, Chen XIN, Dou-yan LI, Lin CHEN, Ming-ying YANG
2021, 42(10): 178-184. doi: 10.12259/j.issn.2095-610X.S20211004
Abstract(5095) HTML PDF(16)
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Objective To establish a high-risk pressure Injury prevention case management model for the elderly inpatients, and evalutate the effect of the high-risk pressure injury prevention case management model for the elderly inpatients. Methods A case mana...
Application Value of Medical Chlorhexidine Gluconate Cotton Tablets in Hemodialysis Catheter Nursing
Zhi-fei MIAO, Dong-jing RONG, Yan-qing CHEN, Shou-kun CHEN
2021, 42(10): 185-188. doi: 10.12259/j.issn.2095-610X.S20211022
Abstract(3109) HTML PDF(9)
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Objective To explore the clinical value of using medical chlorhexidine gluconate cotton tablets to nursing the central venous catheter connector of hemodialysis and reducing catheter-related infection. Methods 90 patients who received central venou...