2022 Vol. 43, No. 12

Original Articles Basic of Medicine
Role and Mechanism of TGF β1 in Platelet Promoting Invasion and Migration of Anaplastic Thyroid Carcinoma Cells
Yu’e JIANG, Zhaoming ZHONG, Yanzhang GAO, Wei WANG, Ruimei SUN, Chuanzheng SUN
2022, 43(12): 1-5. doi: 10.12259/j.issn.2095-610X.S20221201
Abstract(3132) HTML PDF(16) Cited By (1)
Abstract:
Objective This study aims to explore whether platelet (PLT) is involved in regulating the progression of anaplastic thyroid carcinoma (ATC) by secreting transforming growth factor β1 (TGFβ1). Methods The levels of TGFβ1 protein and mRNA in the super...
Effect of VEGF-C on Radiation Sensitivity of Nasopharyngeal Carcinoma CNE-2 Cell Transplanted Mice
Xifang WU, Yong WANG, Lisha PENG, Jie LUO, Feng WANG
2022, 43(12): 6-11. doi: 10.12259/j.issn.2095-610X.S20221205
Abstract(3642) HTML PDF(22)
Abstract:
Objective To investigate the effect of interfering with the expression of VEGF-C on the radiosensitivity of the nasopharyngeal carcinoma CNE-2 cell transplanted tumor and related signaling pathways. Methods The mice with transplanted tumors of nasop...
miR-582-5p Regulating Notch1 to Reduce Myocardial Ischemia-reperfusion Injury
Feng WANG, Wei YANG, Dianlun QIAN, Song MEI, Wenjie WANG, Kexiang FENG, Xiangfeng BAI
2022, 43(12): 12-17. doi: 10.12259/j.issn.2095-610X.S20221207
Abstract(3490) HTML PDF(20) Cited By (2)
Abstract:
Objective To investigate the role of miR-582-5p in regulating Notch1 to protect myocardium, by detecting the expression changes of miR-582-5p and Notch1 after myocardial ischemia reperfusion and HR model of HL-1 cells in mice. Methods The mouse myoc...
Effect of miR-130b-3p on the Reprogramming of Human Dental Origin iPSCs
Xiaobing TAN, Min ZHANG, Yu GUO, Linling DU, Qingyuan DAI
2022, 43(12): 18-22. doi: 10.12259/j.issn.2095-610X.S20221204
Abstract(3072) HTML PDF(14)
Abstract:
Objective To explore the effect of hsa-miR-130b-3p on the reprogramming of human dental iPSCs. Methods LV3 (H1/GFP&Puro)-hsa-miR-130b-3p-mimics plasmid was designed and synthesized. The plasmid was transduced into human DPSCs by Lipofectamine 30...
miR-125b-5p Regulates HK2 to Inhibit Proliferation and Glycolysis of Gallbladder Cancer Cells
Wei ZHANG, Baoquan WANG, Xifeng LEI, Xu WANG, Liang ZHANG
2022, 43(12): 23-29. doi: 10.12259/j.issn.2095-610X.S20221206
Abstract(3874) HTML PDF(27)
Abstract:
Objective To investigate the mechanism of miR-125b-5p regulating the proliferation and glycolysis of gallbladder cancer cells by HK2. Methods NC mimic, miR-125b-5p mimic, miR-125b-5p mimic+pcDNA-NC and miR-125b-5p mimic+pcDNA-HK2 were transfected in...
Association between Morning Sickness and Depression in Pregnancy
Meng CHEN, Dingyun YOU, Chenyu XING, Jinman ZHANG, Hongying LI, Zaiqing QU, Bei ZHU
2022, 43(12): 30-35. doi: 10.12259/j.issn.2095-610X.S20221208
Abstract(3671) HTML PDF(23) Cited By (3)
Abstract:
Objective To investigate the association between morning sickness and depression during pregnancy. Methods The pregnant women who underwent prenatal examination in 3 hospitals in Yunnan Province were selected. The information of pregnant women was c...
Analysis of Genital Chlamydia Trachomatis Infection and Related Factors among Premarital Examination Population in Some Areas of Yunnan Province
Yawen WANG, Jie DAI, Huichao CHEN, Xiaobin ZHANG, Lijuan DONG, Min YANG, Zhijun ZENG, Min CHEN, Wanyue ZHANG, Chaojun YANG
2022, 43(12): 36-40. doi: 10.12259/j.issn.2095-610X.S20221202
Abstract(3211) HTML PDF(15) Cited By (1)
Abstract:
Objectives To investigate the infection status of reproductive tract chlamydia trachomatis (CT) in premarital examination population in Yunnan Province, and to provide basis for prevention and control measures and effect evaluation. Methods A cross-...
Prevalence of Asthma in Rural Residents of Yunnan Province and Social Demographic and Life Behaviorial Risk Factors
Lan LIU, Xuming WANG, Guohui LI, Jinbo LI, Yi MO, Qin LI, Mei ZUO, You HUANG, Le CAI
2022, 43(12): 41-46. doi: 10.12259/j.issn.2095-610X.S20221203
Abstract(3685) HTML PDF(14) Cited By (6)
Abstract:
Objective To analyze the prevalence of asthma and socioeconomic and lifestyle risk factors in rural areas of Yunnan Province. Methods A total of 7572 rural residents aged ≥35 years in Yunnan Province were selected by multi-stage stratified random sam...
Clinical Research
Risk Factors Analysis and Assessment of Ruptured Posterior Communicating Artery Aneurysm
Yuhao DING, Jianren WANG, Tao XIE, Liqing LIN, Zexi LIN, Weiwei ZHU, Xi’an FU, Jun PU
2022, 43(12): 47-52. doi: 10.12259/j.issn.2095-610X.S20221210
Abstract(3707) HTML PDF(16) Cited By (1)
Abstract:
Objective To investigate the risk factors of rupture of posterior communicating aneurysm and screen the morphologic and hemodynamic predictors. Methods A total of 78 patients with posterior communicating aneurysm diagnosed in the neurosurgery depart...
Comparison the Clinical Outcomes of Progestin-Primed Ovarian Stimulation during Follicular Period and Mild-stimulation in Patients with Diminished Ovarian Reserve
Zexing YANG, Ya WEN, Cunmei SU, Huawei WANG, Meng RAO, Yuhang ZHENG, Limei HE
2022, 43(12): 53-57. doi: 10.12259/j.issn.2095-610X.S20221211
Abstract(3250) HTML PDF(13) Cited By (3)
Abstract:
Objective To compare the clinical outcomes of PPOS protocal and mild-stimulation protocal in patients with diminished ovarian reserve function during assisted reproduction and pregnancy. Methods Patients with DOR who underwent the first and second ...
Development of A Plasma Osmolality Prediction Model for the Risk of In-hospital Death in Critically Ill Patients with Acute ST-segment Elevation Myocardial Infarction
Ji JIA, Siming TAO
2022, 43(12): 58-65. doi: 10.12259/j.issn.2095-610X.S20221212
Abstract(3824) HTML PDF(17)
Abstract:
Objective To develop and validate a plasma osmolality prediction model for the risk of in-hospital death in critically ill patients with acute ST-segment elevation myocardial infarction. Methods By retrospective analysis of patients' electronic medi...
Optimal Total Nedaplatin Dose of Concurrent Chemotherapy in Patients with Stage III-IVA Nasopharyngeal Carcinoma
Xiaoli WANG, Ting DING, Meiping JIANG, Kuixuan ZHU, Hongwei YANG
2022, 43(12): 66-74. doi: 10.12259/j.issn.2095-610X.S20221213
Abstract(3753) HTML PDF(6)
Abstract:
Objective To explore the most appropriate total cumulative nedaplatin dose during chemotherapy for patients at the III-IVA stage after induced chemotherapy, and to analyze the effect of the total amount of nedaplatin on the prognosis of nasopharyngea...
Efficacy of Conventional Ultrasound and Contrast-enhanced Ultrasound in Preoperative Diagnosis of Lateral Cervical Lymph Node Metastasis from Papillary Thyroid Carcinoma
Jianfei LU, Rui BU, Xiaoyan LIU, Xing ZHANG, Yu DING, Ran ZHANG
2022, 43(12): 75-80. doi: 10.12259/j.issn.2095-610X.S20221214
Abstract(3958) HTML PDF(11) Cited By (2)
Abstract:
Objective To investigate the ultransonic characteristics of conventional ultrasound (US)combined with Contrast-enhanced ultrasound (CEUS) in the pre-operative diagnosis effectiveness of lateral cervical lymph node metastasis (LCLNM)from papillary thy...
Association between LOXL2 and Snail Expression Levels and Overall Survival Rate after Surgery in Patients with Cholangiocarcinoma
Yao ZOU, Ziyu WANG, Jiao LI, Xingxin LI, Yaqiong SHEN, Jing XU, Yan JIN
2022, 43(12): 81-87. doi: 10.12259/j.issn.2095-610X.S20221215
Abstract(3611) HTML PDF(14) Cited By (1)
Abstract:
Objective To investigate the expression of lysoxygenase-like protein 2 (LOXL2) and Snail in the tissues of cholangiocarcinoma (CCA) and their association with clinicopathological features and postoperative survival. Methods 31 patients with cholangi...
Application of High-flow Nasal Cannula Oxygen Therapy in High-altitude Hypoxemia
Xiaoxue LIU, Li YANG, Chuanyun QIAN
2022, 43(12): 88-92. doi: 10.12259/j.issn.2095-610X.S20221216
Abstract(2971) HTML PDF(9) Cited By (2)
Abstract:
Objective To explore the efficacy of high-flow nasal cannula oxygen therapy on oxygenation in populations at altitudes above 2500 meters. Methods Participants were recruited from medium-altitude Kunming (about 1891 m above sea level) to quickly ente...
Clinical Significance of Uterine Artery and Luteal Blood Flow Doppler Parameters Pregnancy of Uncertain Viability
Xiangbi LI, Yanling HUANG, Yongping LU, Linkun TA, Aitao YIN, Mengxia TANG
2022, 43(12): 93-98. doi: 10.12259/j.issn.2095-610X.S20221218
Abstract(2917) HTML PDF(7) Cited By (1)
Abstract:
Objective To explore the clinical significance of uterine artery and luteal flow Doppler parameters in pregnancy of uncertain viability. Methods A total of 64 women with pregnancy of uncertain viability in first trimester were selected as the resear...
Morphological Study of Meniscus Thickness Measurement in Normal Adults Based on MRI
Sixue PAN, Guangxiong HE, Jiliang XIA, Shuai CHEN, Junyi XIANG, Chaoyu BAO
2022, 43(12): 99-104. doi: 10.12259/j.issn.2095-610X.S20221219
Abstract(3471) HTML PDF(20) Cited By (1)
Abstract:
Objective MRI scanning technique was used to measure the thickness of the anterior and posterior angles of the medial and lateral compartments of the knee joint in normal adults, so as to provide technical means and parameters for the design of total...
Clinical Value of Ultrasound-guided FNA and FNA-TG in Identification of Lymph Node Metastasis of Papillary Thyroid Carcinoma
Hailin ZHANG, Mei ZHU, Yang YANG, Lin WEI, Xi CHEN, Bailing WU
2022, 43(12): 105-110. doi: 10.12259/j.issn.2095-610X.S20221220
Abstract(3204) HTML PDF(13) Cited By (4)
Abstract:
Objective To explore the diagnostic significance of FNA-Tg for lymph nodes with suspected cervical thyroid papillary carcinoma metastasis on the basis of ultrasonic detection and guidance and accurate biopsy of FNA, and establish the threshold of FNA...
Efficacy of Xinmailong Injection on Septic Cardiomyopathy
Wenzhuo LI, Li YANG, Jing XIA
2022, 43(12): 111-116. doi: 10.12259/j.issn.2095-610X.S20221221
Abstract(4579) HTML PDF(12) Cited By (2)
Abstract:
Objective To explore the efficacy of Xinmailong injection on septic cardiomyopathy. Methods A randomized controlled, single-blind study was conducted. 36 patients diagnosed with septic cardiomyopathy were randomly divided into control group (n = 19...
Effect of Abdominal Regional Block Combined with Intravenous Analgesia on Postoperative Complications In Elderly Patients
Yunrui GUO, Hao YANG, Yecai ZHANG, Guoyun ZHANG, Decai WANG, Shulan JIAO, Ningli ZHANG, Chen ZHOU
2022, 43(12): 117-124. doi: 10.12259/j.issn.2095-610X.S20221222
Abstract(3315) HTML PDF(8) Cited By (2)
Abstract:
Objective To investigate the influences of abdominal regional block combined with patient-controlled intravenous analgesia (PCIA) and patient-controlled epidural analgesia (PCEA) on postoperative analgesia, anxiety, nausea, vomiting and inflammatory ...
Application of Pneumoperitoneum Free Transvaginal Natural Orifice Endoscopic Surgery in Ectopic Pregnancy and Related Factors of Operation Time
Yali ZHOU, Hongyun LIAO, Yanjie SHEN, Yiqun DUAN, Lu JIN, Yixian YU, Yanhua LI, Xueyi LV, Chuan WANG, Chao ZHANG
2022, 43(12): 125-130. doi: 10.12259/j.issn.2095-610X.S20221223
Abstract(2077) HTML PDF(10) Cited By (7)
Abstract:
Objective To investigate the application of pneumoperitoneum transvaginal natural orifice endoscopic surgery in ectopic pregnancy and the related factors affecting the operation time in the initial stage. Methods A total of 23 patients who were admi...
Effect of Bidirectional Mirror Multi-dimensional Sensory Stimulation in the Treatment of Stroke with Unilateral Neglect
Simei ZHANG, Hongmei FANG, Xichen YANG, Rong NING, Yijian LONG, Rui LI, Yaju JIN
2022, 43(12): 131-136. doi: 10.12259/j.issn.2095-610X.S20221224
Abstract(4775) HTML PDF(18)
Abstract:
Objective To study the curative effect of bidirectional fold mirror multidimensional spatial sensory stimulation in the treatment of unilateral neglect after stroke. Methods 50 patients with unilateral neglect after stroke were randomly divided into...
Comparison of Efficacy and Postoperative Complications of Lauromacrogol Foam Sclerosant and Lauromacrogol Injection in Patients with Internal Hemorrhoids
Xiaoying CAI, Yi SHEN, Mengjiao GONG, Na LI
2022, 43(12): 137-141. doi: 10.12259/j.issn.2095-610X.S20221225
Abstract(3224) HTML PDF(13) Cited By (11)
Abstract:
Objective To investigate the efficacy of lauromacrogol foam sclerosant and lauromacrogol injection in patients with internal hemorrhoids. Methods A total of 94 patients with internal hemorrhoids treated in Kunming Second People’s Hospital from Febr...
Comparison of Analgesic Level of Ultrasound-guided Paravertebral,Erector Spinae and Serratus Anterior Plane Blocks in Thoracic Surgery
Xiansong LU, Dongyan GUO, Fei QIAO
2022, 43(12): 142-146. doi: 10.12259/j.issn.2095-610X.S20221226
Abstract(2891) HTML PDF(13) Cited By (5)
Abstract:
Objective To compare the difference of cutaneous nociceptive block plane of three commonly used nerve blocks (thoracic paravertebral block, erector spinae plane block and serratus anterior plane block) in thoracic surgery, and to identify the optimal...
AIDS Research
A Cross-sectional Survey on Quality of Life of AIDS Patients with Different Antiretroviral Regimens in Kunming Area
Diandian ZENG, Bo TIAN, Yongmei JIN, Chongxi LI, Fen TENG, Jun LIU
2022, 43(12): 147-152. doi: 10.12259/j.issn.2095-610X.S20221227
Abstract(4674) HTML PDF(20) Cited By (3)
Abstract:
Objective To investigate the quality of life of AIDS patients on different antiretroviral regimens in Kunming. Methods From December 2021 to March 2022, questionnaire survey and Chinese version of WHOQOL-HIV-BREF scale were used in Kunming Third Peo...
Reviews
Advances in the Mechanism of Hepatotoxic Effects Induced by α-amanitin
Yue XU, Chan WANG, Shucheng LIN, Huijie ZHANG, Yi TAN, Shuwei ZHANG, Xiaofeng ZENG, Zhen LI
2022, 43(12): 153-158. doi: 10.12259/j.issn.2095-610X.S20221228
Abstract(3652) HTML PDF(69) Cited By (5)
Abstract:
Amanita is a genus of mushrooms that can cause acute poisoning, and more than 90% of wild mushroom poisoning deaths are caused by its toxins. α-amanitin (α-AMA) is the most toxic component, and the liver is the major target of its toxicity. Transcrip...
A Review on Metabolic Complications and Management after Radical Cystectomy and Orthotopic Neoblastectomy
Haonan DONG, Haifeng WANG, Yinglong HUANG, Hongjin SHI, Lan MAO, Yijie LIU, Jiansong WANG
2022, 43(12): 159-163. doi: 10.12259/j.issn.2095-610X.S20221229
Abstract(3755) HTML PDF(19) Cited By (1)
Abstract:
Bladder cancer is one of the common malignant tumors of urinary system, which can be divided into two categoties, non-muscle-invasive bladder cancer and muscle-invasive bladder cancer. Radical cystectomy is the treatment of choice for muscle-invasive...
Risk Factors of Gastroesophageal Reflux in Patients with Swallowing Disorders
Kerong CHEN, Wengang ZHOU, Hongling SHI, Tianyun LIU, Huixian LIN, Mei ZHANG
2022, 43(12): 164-170. doi: 10.12259/j.issn.2095-610X.S20221230
Abstract(4276) HTML PDF(32) Cited By (3)
Abstract:
Swallowing disorders seriously affect people’s physical and mental health and has become a major clinical and public health problem. GERD is one of the common complications in patients with dysphagia and has a very significant correlation with swallo...
Teaching Research
Application of TBL Combined with PBL in Cultivating of Scientific Research Ability of Undergraduate Nursing Students
Guangliu WU, Xuemei YANG, Mingying YANG, Xijuan ZHAO, Ya WANG, Rujiao YIN, Xiaoying ZHOU
2022, 43(12): 171-176. doi: 10.12259/j.issn.2095-610X.S20221231
Abstract(3130) HTML PDF(16) Cited By (2)
Abstract:
Objective To explore the application effect of TBL combined with PBL in the cultivation of scientific research ability of undergraduate nursing students. Methods Convenience sampling method was adopted to select nursing undergraduates from Kunming Me...
Nursing Forum
Practical Effect of Enhanced Recovery after Surgery Nursing among Patients with Myomectomy
Jinmei DUAN, Juli SHEN, Huifang JIA, Mei HUANG, Huixian LIN
2022, 43(12): 177-180. doi: 10.12259/j.issn.2095-610X.S20221232
Abstract(3088) HTML PDF(15) Cited By (16)
Abstract:
Objective To study the nursing effect of enhanced recovery after surgery nursing among Gynecological patients with myomectomy. Methods A total of 111 patients were selected with myomectomy admitted to the Gynecology of the Third People’s Hospital of...