2022 Vol. 43, No. 11

Original Articles Basic of Medicine
Effects of Modulation of CDC42 Activity in Hippocampal Neurons on Memory and Anxiety Behaviors of Mice
Chaojie ZOU, Yikai TANG, Shuwen DU, Yuqi CHENG
2022, 43(11): 1-8. doi: 10.12259/j.issn.2095-610X.S20221105
Abstract(3557) HTML PDF(135) Cited By (3)
Abstract:
Objective To establish an animal model to investigate the relationship between cell division cycle 42 (CDC42) and cognitive deficits in hippocampal neurons. Methods Adenovirus with CDC42 mutant gene was packaged to infect excitatory neurons in the h...
Effects of Perindopril on Intestinal Microecology in Obese Rats
Yandong GUO, Rudan HONG, Yanjiao WANG, Teng ZHANG, Yuemei FENG, Nishang ZHANG, Ying QIAN, Zaogai YANG, Fei MI, Jianzhong YIN
2022, 43(11): 9-16. doi: 10.12259/j.issn.2095-610X.S20221101
Abstract(2969) HTML PDF(42) Cited By (2)
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Objective To study the effect of perindopril on body weight, blood lipids and intestinal flora of obese rats. Methods SPF Wistar rats were randomly divided into normal group, model group, perindopril low-dose and high-dose groups (0.4, 2 mg/(kg·d))...
Epidemic Trends and Characteristics of Hypertension among Primary and Secondary Students from 2017 to 2020 in Kunming,Yunnan
Yunjuan YANG, Tao MA, Yuanyi ZHA, Litao CHANG, Hong LIU, Fan YANG, Limei DAI, Fang LI
2022, 43(11): 17-21. doi: 10.12259/j.issn.2095-610X.S20221104
Abstract(3993) HTML PDF(215) Cited By (4)
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Objectives To analyze the prevalence trend and epidemic characteristics of hypertension among primary and middle school students in Kunming, and to provide scientific basis for the formulation of prevention and intervention strategies for hypertensio...
Expressions of ROR1 in Lung Adenocarcinoma and Its Relationship with Spread Through Air Apace
Huajun ZHAO, Guoqing PAN, Ying TANG, Zhiyuan WANG, Xiaowei ZHAO, Xiaoyu TUO
2022, 43(11): 22-29. doi: 10.12259/j.issn.2095-610X.S20221128
Abstract(3662) HTML PDF(150) Cited By (1)
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Objective To study the relationship between the expression of receptor tyrosine kinase-like orphan receptor 1 (ROR1) and spread through air space (STAS) in lung adenocarcinoma tissues. Methods We collected 618 cases of lung adenocarcinoma from June ...
Nutritional Status of Vitamin A among Adults of Ethnic Minority Groups Native to Yunnan Province
Qiang ZHANG, Juanjuan LI, Qingqing WAN, Jiang ZHAO, Yanling YANG, Yuan RUAN, Zhitao LIU
2022, 43(11): 30-35. doi: 10.12259/j.issn.2095-610X.S20221112
Abstract(3953) HTML PDF(112) Cited By (1)
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Objective To assess the nutritional status of vitamin A among adults of ethnic minority groups native to Yunnan Province, and provide scientific evidence for healthy eating promotions. Methods Between 2016 and 2020, 841 adults were randomly sampled...
Effects of Puerarin on Th17/Treg Cell Immune Homeostasis and the Expression of Related Transcription Factors in Rats with Periodontitis
Le ZHAN, Ruiyu MA, Ni WAN, Liwen MO, Huiying CHEN, Li ZHANG
2022, 43(11): 36-43. doi: 10.12259/j.issn.2095-610X.S20221129
Abstract(3590) HTML PDF(47) Cited By (7)
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Objective To study the effects of puerarin on the immune homeostasis of T helper 17 (Th17)/regulatory T (Treg) cells and the expression of related transcription factors in rats with periodontitis. Methods A rat periodontitis model was established us...
Clinical Research
Risk Factors Analysis and Prediction Model Establishment of Refeeding Syndrome in ICU Patients with Sepsis
Hong WANG, Dexing YANG, Qiang WANG, Weiyu ZHOU, Jiefu TANG, Zhenfang WANG, Kai FU, Shengzhe LIU, Rong LIU
2022, 43(11): 44-51. doi: 10.12259/j.issn.2095-610X.S20221102
Abstract(4056) HTML PDF(41) Cited By (21)
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Objective To explore the relevant risk factors for Refeeding Syndrome (RFS) in ICU patients with sepsis, and to establish a prediction model of RFS based on the selected risk factors. Methods The clinical data of sepsis patients admitted to the ICU...
Application of Staged Island Prepuce Flap Urethral Plate Reconstruction in Severe Hypospadias
Shipeng FAN, Jihong SHEN, Haiyuan LI, Hongbin GAO, Ning LUO, Hui ZHAO
2022, 43(11): 52-57. doi: 10.12259/j.issn.2095-610X.S20221106
Abstract(2192) HTML PDF(108) Cited By (1)
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Objective To study the clinical effect of staged Island prepuce flap urethral plate reconstruction in the treatment of severe hypospadias. Methods Twenty-eight patients with severe hypospadias treated in our hospital from November 2013 to March 2022...
Establishment and Application Evaluation of Automatic Verification System for Coagulation Test Reports
Dongmei YANG, Chunyan XIA, Tingjun LUO, Yixiao WANG, Zhen JIN
2022, 43(11): 58-62. doi: 10.12259/j.issn.2095-610X.S20221107
Abstract(2766) HTML PDF(123)
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Objective To establish an automatic review system for blood coagulation test report and evaluate its application effect. Methods The rules for the examination of coagulation test reports were written into Lis Procedure. A total of 6281 reports that ...
Effect of Time Interval on the Outcome with Transarterial Chemoembolization Followed Microwave Ablation with Hepatocellular Carcinoma
Haiyan FU, Junfang YAN, Hongjuan LI, Lin WANG, Jie ZHANG, Yujun ZHOU, Bin XU, Yu LUO
2022, 43(11): 63-70. doi: 10.12259/j.issn.2095-610X.S20221127
Abstract(3746) HTML PDF(123)
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Objective To analyse the effect of time interval on the outcome of microwave ablation (MWA)treatment of hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE). Methods A retrospective analysis of recurrent 71 HCC patients after ...
CBCT Imaging Study of the Correlation between the Anatomy of Greater Palatine Foramen and the Morphology of Palatal Vault in Adults
Jiawen YANG, Qihong PU, Jianfeng XIAO, Qiumin HE, Dahai YIN
2022, 43(11): 71-76. doi: 10.12259/j.issn.2095-610X.S20221109
Abstract(5530) HTML PDF(22)
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Objective To explore the greater palatine foramen anatomical position and its relationship with the morphology of palatal vault in adults, so as to provide theoretical basis for the clinic operation related to palate. Methods We collected CBCT image...
Study on Differential Expression Profile of lncRNA between Concurrent Chemoradioresistant Nasopharyngeal Carcinoma Cell Lines and Parental Cell Lines
Qiuyan LIU, Wei XIONG, Cheng LI
2022, 43(11): 77-84. doi: 10.12259/j.issn.2095-610X.S20221108
Abstract(3276) HTML PDF(31)
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Objective To analyze the long non coding RNA (lncRNA) differentially expressed between nasopharyngeal carcinoma cell lines resistant to concurrent radiotherapy and chemotherapy and their parent cell lines, and explore the possible role of lncRNA in n...
Clinical Comparison of Biliary Iodine-125 Stent and Bare Metal Stent in Treatment of Bismuth Corlette III Cholangiocarcinoma Complicated with Obstructive Jaundice
Fei SONG, Yingying XIANG, Jiayin CHE, Hongyang LI, Wenyong XU, Lingxiao WEI, Ming HUANG
2022, 43(11): 85-89. doi: 10.12259/j.issn.2095-610X.S20221110
Abstract(3331) HTML PDF(26) Cited By (2)
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Objective To compare the efficacy of biliary 125I seed stent and bare metal stent in the treatment of Bismuth Corlette Ⅲ cholangiocarcinoma complicated with obstructive jaundice. Methods A total of 51 patients with malignant biliary obstruction cau...
Effect of Comprehensive Rehabilitation Combined with Soft and Hard Occlusion Therapy for Disc Anchor Surgery of Anterior Disc Displacement with Reduction
Li ZHANG, Linjia XUE, Yi BAO, Yong CHEN, Chengfeng SUN, Yu DING
2022, 43(11): 90-98. doi: 10.12259/j.issn.2095-610X.S20221111
Abstract(4842) HTML PDF(23) Cited By (2)
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Objective To observe the effect of comprehensive rehabilitation combined with soft and hard occlusion therapy for disc anchor surgery of anterior disc displacement with reduction. Methods A total of 60 patients with anterior disc displacement with r...
Early Effectiveness of Bedaquiline Containing Regimen in Treatment of Multidrug-resistant and Extensively Drug-resistant Pulmonary Tuberculosis: An One-arm Observational Study of 24 Weeks
Chunhong YU, Yanhong ZHAO, Xing LIU, Lingjun SHEN, Weixian LI, Haiwen LI, Hao FAN
2022, 43(11): 99-106. doi: 10.12259/j.issn.2095-610X.S20221113
Abstract(3332) HTML PDF(30) Cited By (2)
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Objective To evaluate the efficacy of a bedaquiline-containing regimen in the treatment of multidrug-resistant/extensively drug-resistant tuberculosis, and to explore the adverse reactions, so as to provide a reference for safe and rational drug use ...
Relationships between Large Artery Atherosclerotic Stroke and Cardiac Function
Yao YANG, Jianxiong LIU, Yun ZHANG, Fanyi KONG, Shixiang LIU
2022, 43(11): 107-111. doi: 10.12259/j.issn.2095-610X.S20221126
Abstract(3309) HTML PDF(35) Cited By (1)
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Objective To analyze the difference in cardiac function between intracranial and extracranial atherosclerotic stroke and aortic arch atherosclerotic stroke, so as to investigate the effect of cardiac function on the prognosis of large artery atherosc...
Effects of Prepregnancy Body Mass Index, Hemoglobin and Gestational Weight Gain on Pregnancy Outcomes
Yanzheng YANG, Yu'e ZHOU, Tuan LI, Shuangyan CHEN, Sisi LI
2022, 43(11): 112-117. doi: 10.12259/j.issn.2095-610X.S20221103
Abstract(3109) HTML PDF(192) Cited By (21)
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Objective To investigate the effects of hemoglobin level during pregnancy, pre-pregnancy body mass index and weight gain during pregnancy on pregnancy outcomes. Methods Retrospective research was used to analyze the medical records of delivery women...
Application Value of CBCT Imaging in Salivary Adenography
Qihong PU, Qiumin HE, Dawei ZHENG, Dahai YIN, Yan WANG, Hai PENG
2022, 43(11): 118-123. doi: 10.12259/j.issn.2095-610X.S20221114
Abstract(3804) HTML PDF(110)
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Objective To explore the application value of CBCT imaging in the diagnosis of salivary gland disease by sialography. Methods After sialography,51 patients performed traditional pantomography and CBCT scans, Multi-planar images(MPR), synthetic pant...
Efficacy and Safety of Sofosbuvir-based Drugs for the Treatment of Patients with Chronic Hepatitis C Genotype 3: A Single Centre Real-world Retrospective Analysis
Yanwen XU, Xin WANG, Hua JIANG, Chenchen LIANG, Li LIU, Shenghao LI, Jianpeng GAO
2022, 43(11): 124-129. doi: 10.12259/j.issn.2095-610X.S20221115
Abstract(3282) HTML PDF(33) Cited By (2)
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Objective To study the efficacy and safety of real-world sofosbuvir/velpatasvir (SOF/VEL) in combination with or without ribavirin (RBV) in the treatment of patients with chronic hepatitis C (CHC) genotype 3 in Yunnan. Methods A total of 219 patient...
Clinical Application of Linaclotide Combined with Compound Polyethylene Glycol Electrolyte in Bowel Preparation in Patients with Chronic Constipation
Zhenguang QI, Xiaoyun LI, Weiwei ZHANG
2022, 43(11): 130-135. doi: 10.12259/j.issn.2095-610X.S20221116
Abstract(2317) HTML PDF(28) Cited By (15)
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Objective To study the effect and safety of linaclotide combined with compound polyethylene glycol electrolyte (PEG) in bowel preparation in patients with chronic constipation. Methods A total of 174 patients with chronic constipation who underwent ...
Clinical Efficacy and Safety of Sacubatril Valsartan in Patients with Reduced Ejection Fraction Combined with Hypotensive Heart Failure
Yanfei WANG, Juan MA, Yunqiao YANG
2022, 43(11): 136-140. doi: 10.12259/j.issn.2095-610X.S20221117
Abstract(3307) HTML PDF(23) Cited By (10)
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Objective To observe the clinical efficacy and safety of sacubitril-valsartan in patients with reduced ejection fraction and hypotensive heart failure. Methods A total of 100 patients with decreased ejection fraction combined with hypotension and he...
Analysis on the Positive Test Results of Seven Joint Tests for Respiratory Pathogens in Hospitalized Children in Anning Area
Jianhong XU, Bingkun ZHANG, Aimin SHI, Qiong DU
2022, 43(11): 141-145. doi: 10.12259/j.issn.2095-610X.S20221118
Abstract(5169) HTML PDF(111)
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Objective To analyze the positive test results of respiratory tract virus pathogens in hospitalized children in Anning area. Methods A total of 1766 hospitalized children in Anning District from September 2019 to February 2022 were selected as subje...
Efficacy and Safety of rhTPO Combined with High-dose Short-cycle Dexamethasone Regimen in Treatment of ANa-positive Adult Immune Thrombocytopenia
Yanling JIN, Jianmei LI
2022, 43(11): 146-150. doi: 10.12259/j.issn.2095-610X.S20221119
Abstract(3048) HTML PDF(26) Cited By (1)
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Objective To investigate the combination of recombinant human thrombopoietin (rhTPO) combined with high-dose short-cycle dexamethasone (hexadecadrol, HDD) regimen in the treatment of anti-nuclear antibody (ANA) positive adults with immune thrombocyto...
AIDS Research
Effect of Early Interventional Therapy with Bronchoscopic Alveolar Lavage on AIDS Patients Complicated with Severe Pneumonia
Le ZHANG, Yuanqiang HE, Jiawei XIA, Shu LIU, Bin BAI, Xing LIU
2022, 43(11): 151-155. doi: 10.12259/j.issn.2095-610X.S20221120
Abstract(4783) HTML PDF(27) Cited By (4)
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Objective To explore the effect of early interventional therapy with bronchoscopic alveolar lavage on AIDS patients complicated with severe pneumonia. Methods Adult AIDS patients complicated with severe pneumonia (44 cases) who were hospitalized in ...
Reviews
Research Progress of Single Nucleotide Polymorphism and Adolescent Idiopathic Scoliosis
Yunxin ZHAO, Fanyuan MENG, Wei LIU, Huidong WU, Changliang LUO, Bin LI, Lijuan AO, Moxian CHEN
2022, 43(11): 156-164. doi: 10.12259/j.issn.2095-610X.S20221121
Abstract(4180) HTML PDF(30) Cited By (1)
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The incidence of adolescent idiopathic scoliosis (AIS) worldwide is 1%~3%, the base of the diseased population is large, and it causes both physical and psychological pains to patients. Numerous studies have shown that genetic factors may play an imp...
Progress in Etiology and Pathogenesis of Liver Fibrosis
Di HE, Peng CHEN, Feng LIU, Yang XU, Lei HAN, Wenjing DING
2022, 43(11): 165-171. doi: 10.12259/j.issn.2095-610X.S20221122
Abstract(4321) HTML PDF(236) Cited By (31)
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Liver fibrosis (HF) is the result of abnormal deposition of various extracellular matrix (ECM) caused by the over-repair response of various chronic liver diseases, such as genetic-related diseases, chronic viral hepatitis, alcoholic hepatitis, chole...
Teaching Research
Application of Rain Classroom Combined Scenario Simulation Based on Target Teaching Theory in Teaching Intern Nursing Students in Radiotherapy Department
Jiang ZHANG, Bingkun YANG, Wenbo PING, Xijuan ZHAO, Yan SU, Jiang WU
2022, 43(11): 172-177. doi: 10.12259/j.issn.2095-610X.S20221123
Abstract(3204) HTML PDF(25) Cited By (5)
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Objective To explore the application effect of rain classroom combined scenario simulation teaching method based on Bloom’s target teaching theory in the teaching of intern nursing students in the radiotherapy department. Methods 120 nursing student...
Nursing Forum
Effect of Reasonable Sedation on Image Quality before PET/CT Examination in Children with Epilepsy
Yike TANG, Rencai LU, Yunhai JI, Bo SHE, Yanping QING
2022, 43(11): 178-184. doi: 10.12259/j.issn.2095-610X.S20221124
Abstract(2964) HTML PDF(25)
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Objective To explore the effects of natural sleep and drug sedation on the degree of cooperation and image quality in children with epilepsy, and to guide nurses to master the advantages and disadvantages of the two methods. Methods A total of 72 ch...
Impact of Path-based Symptom Management Education Driven by Multidisciplinary Teams on The Quality of Life of Patients with Chronic Heart Failure
Ming JIN, Mei CEN, Lijing ZHAO
2022, 43(11): 185-192. doi: 10.12259/j.issn.2095-610X.S20221125
Abstract(4083) HTML PDF(37) Cited By (3)
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Objective To improve effectively the quality of life outside the hospital for patients with Chronic Heart Failure (CHF) through the construction of a Multidisciplinary Teams (MDT)-driven “path-based” core symptom group management mode based on Sympto...