2022 Vol. 43, No. 6

Original Articles Basic of Medicine
Effect of AK4 on Proliferation and Migration of Intrahepatic Bile Duct Carcinoma Cell HUCCT1
Zhoujun LIAO, Shaohua YANG, Lixin LIU, Sheng HU, Yihui CHEN, Qiang KANG, Xiaowen ZHANG
2022, 43(6): 1-6. doi: 10.12259/j.issn.2095-610X.S20220611
Abstract(3518) HTML PDF(119) Cited By (1)
Abstract:
Objective To investigate the effects of AK4 on the proliferation and migration of intrahepatic bile duct carcinoma cells HUCCT1. Methods Small interfering RNA (siRNA) technology was used to target the silencing of AK4 expression in HUCCT1 of intrahe...
Expression and Clinical Significance of Eukaryotic Translation Initiation Factors 5A2 and Ki67 in Intrahepatic Cholangiocarcinoma
Gang LI, Shaohua YANG, Meng SHEN, Nan XIE, Guanbo ZHANG, Jiaxing WANG, Jinsong LI
2022, 43(6): 7-12. doi: 10.12259/j.issn.2095-610X.S20220630
Abstract(4683) HTML PDF(34)
Abstract:
Objective To analyze the clinical significance and correlation of eukaryotic translation initiation factor 5A2 (EIF5A2) and Ki67 expression in intrahepatic cholangiocarcinoma tissues. Methods Paraffin sections were collected from 118 patients with i...
A Preliminary Study of CASR/VDR/PTH1R Signaling Pathway in the Pathogenesis of Calcium-containing Kidney Stones
Jingling LI, Kunbin KE, Zhencheng WANG, Deqiang QIN, Hao LI
2022, 43(6): 13-18. doi: 10.12259/j.issn.2095-610X.S20220609
Abstract(2901) HTML PDF(28) Cited By (1)
Abstract:
Objective To study the role and mechanism of CASR, VDR, PTH1R and other genes in the occurrence of calcium-containing kidney stones. Methods The renal medulla of patients with renal calculi was selected as the experimental group, and the normal rena...
Effects of Different Penetration Enhancers on in vitro Transdermal Permeation of Bagui Zhitong Cream
Jinli ZHANG, Jiahua MEI, Chengcheng LIAO, Dan HU, Hong HUANG, Yuanwen LI
2022, 43(6): 19-24. doi: 10.12259/j.issn.2095-610X.S20220623
Abstract(2060) HTML PDF(19) Cited By (3)
Abstract:
Objective To study the best preparation method of Bagui Zhitong cream, to determine the best matrix formulation, and to investigate the effect of different Penetration Enhancers on in vitro Transdermal Permeation of Bagui Zhitong Cream. Methods We p...
Analysis of Differential Gene Expression and Function in Peripheral Blood of Patients with Coronary Heart Disease and Acute Myocardial Infarction
Wenqing MIAO, Yu WANG, Xiaoli ZHAO, Nini TIAN, Liying YOU
2022, 43(6): 25-34. doi: 10.12259/j.issn.2095-610X.S20220614
Abstract(4233) HTML PDF(30) Cited By (1)
Abstract:
Objective To investigate the differential gene expression and function of peripheral blood monocytes in patients with coronary heart disease and acute myocardial infarction. Methods Patients receiving coronary angiography in Kunming First People’s H...
Research about Adverse Childhood Experiences and Behavior of Injection Drug Use among Border Drug Users
Jiashuang LI, Jing LI, Jing YOU, Rong LU
2022, 43(6): 35-40. doi: 10.12259/j.issn.2095-610X.S20220608
Abstract(2040) HTML PDF(31) Cited By (2)
Abstract:
Objective To understand the basic features of the border drug users, and explore association between adverse childhood experiences (ACEs) and injecting drug use behavior among border drug users. Methods The cross-sectional study was conducted from J...
Recombinant Human Epidermal Growth Factor on the Repairing Effect of Sensitive Skin in High Altitude Areas in Yunnan Province
Qingzhu ZHOU, Zhuo GONG, Xian ZHAO, Boyan LIU, Wenli HUANG, Jia HE, Liu LIU, Pufei PU
2022, 43(6): 41-45. doi: 10.12259/j.issn.2095-610X.S20220627
Abstract(3261) HTML PDF(27) Cited By (3)
Abstract:
Objective To observe the repairing effect of recombinant human epidermal growth factor (EGF) on sensitive skin in high altitude area of Yunnan province. Methods This study retrospectively analyzed 100 cases of sensitive skin female patients aged 20 ...
Clinical Research
Clinical Efficacy and Safety Evaluation of Fecal Bacteria Transplantation by Different Ways on Ulcerative Colitis
Xiaolin LIU, Xiaocui CHEN, Yang SUN, Minli LI, Yinglei MIAO
2022, 43(6): 46-51. doi: 10.12259/j.issn.2095-610X.S20220612
Abstract(3594) HTML PDF(30) Cited By (6)
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Objective To evaluate the efficacy and safety of upper and lower alimentary canal fecal bacteria transplantation in the treatment of ulcerative colitis, in order to guide clinical practice. Methods A total of 74 patients with mild to moderate activ...
Effects of Percutaneous Transluminal Angioplasty Plus Open Operation in Hemodialysis Patients with Type I and II Upper Limb Arteriovenous Fistula Stenosis
Xixiong SU, Wei XU, Liqi XU, Qin YANG, Yunli YANG
2022, 43(6): 52-55. doi: 10.12259/j.issn.2095-610X.S20220626
Abstract(3479) HTML PDF(20) Cited By (3)
Abstract:
Objective To discuss the effects of percutaneous transluminal angioplasty (PTA) plus open operation in hemodialysis patients with type I and II upper limb arteriovenous fistula (AVF) stenosis. Methods Ninty hemodialysis patients who had type I and I...
Clinical Effects on Sternoclavicular Joint Dislocation with Bridge-link Combined Fixation System
Dingkai ZHOU, Chengyi ZI, Ziyang ZHAO, Xiaofei LI, Rui ZHANG, Yonggang YANG, Jingwu LIAO, Daohong ZHAO
2022, 43(6): 56-62. doi: 10.12259/j.issn.2095-610X.S20220625
Abstract(2218) HTML PDF(25) Cited By (2)
Abstract:
Objective To observe the clinical effect of Bridge-link Combined Fixation System (BCFS) in the treatment of Sternoclavicular dislocations (SCD) . Methods From October 2016 to September 2021, 29 patients with acute closed SCD were treated with BCFS,...
The Relationship between Maxillary Midline Diastema and Maxillary Labial Frenum
Jianhua WU, Lili YANG, Ting ZHOU, Sijia MA
2022, 43(6): 63-67. doi: 10.12259/j.issn.2095-610X.S20220619
Abstract(2868) HTML PDF(29) Cited By (1)
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Objective To find out the relationship between maxillary midline diastema and maxillary labial frenum, develop an appropriate diagnosis and treatment plan for patients with aesthetic demands in the clinic. Methods 106 qualified volunteers were recru...
Analgesia of Ultrasound-guided Single-dose Adductor Canal Block with Dexmedetomidine Combined with Ropivacaine after Patella Fracture Surgery in Adults
Yue LU, Changming QIU, Yunli YANG, Zhiguo HUANG, Zhigui LI, Weiqing MA, Na LI
2022, 43(6): 68-73. doi: 10.12259/j.issn.2095-610X.S20220613
Abstract(4167) HTML PDF(23) Cited By (11)
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Objective To compare the analgesic effect between ultrasound-guided single-dose adductor canal block with dexmedetomidine combined with ropivacaine and continuous femoral nerve block with ropivacaine after patella fracture surgery. Methods 31 patien...
Evaluation of Drug Utilization in the Infected Patients with ESBLs Produced by Enterobacteriaceaein
Xueting YANG, Huifeng ZHANG
2022, 43(6): 74-78. doi: 10.12259/j.issn.2095-610X.S20220621
Abstract(3768) HTML PDF(21) Cited By (5)
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Objective To evaluate the rationality of antibiotics utilization in the infected patients with ESBLs produced by Enterobacteriaceaein one hospital. Methods The methods of drug utilization review(DUR) and drug utilization evaluation(DUE) were used to...
Value of Different Sections of Echocardiography in the Diagnosis of Fetal Congenital Vascular Ring
Linkun TA, Yanling HUANG, Jingqiu ZhANG, Yongping LU
2022, 43(6): 79-84. doi: 10.12259/j.issn.2095-610X.S20220615
Abstract(3411) HTML PDF(25) Cited By (3)
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Objective To analyze the diagnostic value of different sections of echocardiography in fetal congenital vascular ring (CVR). Methods The echocardiography data and follow-up results of 60 cases of CVR diagnosed in Yunnan University Hospital from Jan...
Clinical Data Analysis of 101 Cases of Very Preterm Infants
Ziwei LI, Meiqun GU, Xiaozhi XU, Lianfang TANG, Xiaoyan XU, Jinghui YANG, Kai BI, Hongying MI
2022, 43(6): 85-91. doi: 10.12259/j.issn.2095-610X.S20220610
Abstract(2517) HTML PDF(16)
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Objective To investigate the birth status, serious complications, outcome and follow-up of very premature infants, and to analyze the influencing factors. Methods The clinical data of very preterm infants hospitalized in our department from January...
Application of MTHFR C677T Combined with CYP2C19 Gene Detection after Percutaneous Paclitaxel Eluting Coronary Balloon Dilatation Coronary Angioplasty
Shuo WANG, Qi RU, Xiaochan ZHANG, Zhiyu YANG, Le WANG, Liu LI
2022, 43(6): 92-98. doi: 10.12259/j.issn.2095-610X.S20220618
Abstract(3156) HTML PDF(21)
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Objective To investigate the value of MTHFR C677T combined with CYP2C19 gene detection in patients after paclitaxel releasing coronary balloon catheter. Methods 300 patients who underwent paclitaxel releasing coronary balloon catheterization were ra...
Differences of Adverse Events and Survival Rates of Patients with Premature Coronary Artery Disease after PCI in Different Age Groups
Huan LI, Zhong ZHONG
2022, 43(6): 99-104. doi: 10.12259/j.issn.2095-610X.S20220607
Abstract(2843) HTML PDF(19) Cited By (5)
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Objective To investigate the adverse events and survival rates differences of patients with premature coronary artery disease after PCI in different age groups. Methods The general and clinical data, incidence of adverse events and survival rates of...
Role of Postural Reduction and Rehabilitation Guidance in the Treatment of Vertebral Osteoporotic Fractures by Vertebroplasty
Xiaona ZHAI, Lin FANG, Yong LI, Fang YU, Qiuyan PEI, Ping WANG, Zuoming YANG
2022, 43(6): 105-109. doi: 10.12259/j.issn.2095-610X.S20220602
Abstract(1998) HTML PDF(12) Cited By (1)
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Objectives To analyze the role of rehabilitation guidance combined position reduction in kyphoplasty for osteoporotic vertebral fractures. Methods A total of 68 patients with vertebral osteoporotic fractures admitted to our hospital from August 2018...
Effect Evaluation of Exercise Rehabilitation on Patients with Chronic Heart Failure
Hairu WANG, Pinghui ZHU, Jun WANG
2022, 43(6): 110-116. doi: 10.12259/j.issn.2095-610X.S20220617
Abstract(3710) HTML PDF(12) Cited By (8)
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Objective To explore the clinical therapeutic effect of chronic heart failure patients on the basis of basic disease treatment and standardized drug treatment combined with exercise rehabilitation. Methods A total of 110 CHF patients admitted to a h...
Feasibility of Optic Nerve Sheath Diameter to Guide the Treatment of Dehydration in Patients Undergoing Glioma Surgery
Wenhua XIA, Xiang SUN, Jianlin SHAO
2022, 43(6): 117-121. doi: 10.12259/j.issn.2095-610X.S20220620
Abstract(2074) HTML PDF(8)
Abstract:
Objective To investigate the feasibility of ultrasonic measurement of optic nerve sheath diameter (ONSD) in the treatment of dehydration of intracranial hypertension (ICH) in patients undergoing glioma surgery. Methods A total of 40 patients with cr...
Application of Internet Technology in Triage Prevention and Control of Pediatric Infectious Diseases
Yuting ZHENG, Yunshan LIAO, Na FAN, Wenying PAN, Wenjuan ZHENG, Yajuan HAN
2022, 43(6): 122-126. doi: 10.12259/j.issn.2095-610X.S20220624
Abstract(4649) HTML PDF(14) Cited By (2)
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Objective To observe and explore the application methods and effects of Internet information technology in the triage prevention and control of pediatric infectious diseases. Methods We randomly selected 500 patients of infectious diseases from June...
Effect of Matrix Radiofrequency Combined with Biofeedback Electrical Stimulation on Uterine Prolapse
Zhuwei GAO, Xinghui CHEN, Junjing HE, Hongxian LI, Lisha MA
2022, 43(6): 127-131. doi: 10.12259/j.issn.2095-610X.S20220604
Abstract(2585) HTML PDF(15) Cited By (13)
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Objective To investigate the clinical effect of gynecological RF combined with biofeedback electrical stimulation on uterine prolapse. Methods A total of 150 patients who met the inclusion criteria were randomly divided into control group and observ...
Status of the Readiness for Hospital Discharge and Its Influencing Factors in Patients with Rheumatoid Arthritis
Yujuan DU, Huaying CHEN, Xiaofang TIAN, Yuting LI, Jingwen YAO, Mingyue ZHAO, Lifen ZHANG
2022, 43(6): 132-139. doi: 10.12259/j.issn.2095-610X.S20220603
Abstract(3046) HTML PDF(8) Cited By (9)
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Objective To investigate the status and influencing factors of discharge readiness in patients with rheumatoid arthritis, and to provide scientific basis for improving discharge readiness services for patients with rheumatoid arthritis and developing...
AIDS Research
Pathogen Distribution and Antimicrobial Susceptibility of Bacterial Bloodstream Infection in AIDS Patients
Bo TIAN, Jun LIU, Haiwen LI, Wei SONG, Haiyun CHEN, Jianjun SUN
2022, 43(6): 140-146. doi: 10.12259/j.issn.2095-610X.S20220616
Abstract(3858) HTML PDF(19) Cited By (2)
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Objective To explore the prevalence of bacterial bloodstream infection in AIDS patients, and to learn the pathogen species drug resistance among AIDS patients . Methods We retrospectively collected the data of AIDS patients with bacteria isolated fr...
Reviews
Advances in Research Progress on the Therapeutic Function of Biliverdin
Wenya BAI, Yuan YANG, Siying HUO, Xin YANG, Jianlin SHAO
2022, 43(6): 147-153. doi: 10.12259/j.issn.2095-610X.S20220601
Abstract(4565) HTML PDF(70) Cited By (4)
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Biliverdin and bilirubin are the products of heme metabolism. Many studies have found that biliverdin can continuously consume oxygen free radicals as well as activate biliverdin reductase, relying on the biliverdin-bilirubin redox recycling system. ...
Application of Whole-cell Patch Clamp Techniques in Inherited Long QT Syndrome and Sudden Unexplained Death
Junjie SHU, Hongyu CHEN, Kai LIU, Puping LEI
2022, 43(6): 154-158. doi: 10.12259/j.issn.2095-610X.S20220629
Abstract(2485) HTML PDF(24)
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Cardiac channelopathy caused by genetic mutations have been recognized as a leading cause of sudden unexplained death (SUD). Long QT syndrome is one of the most common cardiac channelopathies and its pathogenic genetic mutations have been continuousl...
Advances in Research on Hertwig’s Epithelial Root Sheath Cells
Fei BI, Weihua GUO
2022, 43(6): 159-166. doi: 10.12259/j.issn.2095-610X.S20220628
Abstract(2579) HTML PDF(54)
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Hertwig's epithelial root sheath (HERS) cells are a special group of cells that play important roles during root development and formation of periodontal tissues. This paper summarizes the origin and morphological structure of HERS cells, as well as ...
Teaching Research
Application of Mini-CEX in the Standardized Training of Residents in Nephrology Department
Zhenkun HE, Yi ZENG, Yunjuan LIAO, Xiaoliang CHENG
2022, 43(6): 167-170. doi: 10.12259/j.issn.2095-610X.S20220606
Abstract(3090) HTML PDF(15) Cited By (9)
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Objective To explore the application of Mini-CEX in the standardized training of residents in nephrology department. Methods Residents who were trained in the Nephrology Department of the Second Affiliated Hospital of Kunming Medical University from...
Nursing Forum
Efficacy of Pentatone Therapy Combined with Non-nutritive Sucking in Feeding Premature Infants
Yanzheng YANG, Yue ZHOU, Tuan LI, Shuangyan CHEN
2022, 43(6): 171-176. doi: 10.12259/j.issn.2095-610X.S20220622
Abstract(2751) HTML PDF(9) Cited By (12)
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Objective To explore the effect of pentatone therapy combined with non-nutritive sucking in feeding premature infants. Methods A total of 120 premature infants admitted to the Neonatal Intensive Care Unit (NICU) of the Third People’s Hospital of Yunn...
Effect of Nurse-led Nursing Model in Patients with Laparoscopic Hepatectomy
Jing GUO, Ying ZHANG, Fengxia YANG, Yan ZHOU, Tao FENG
2022, 43(6): 177-180. doi: 10.12259/j.issn.2095-610X.S20220605
Abstract(3696) HTML PDF(10) Cited By (1)
Abstract:
Objective To explore the effect of nurse-led nursing mode in laparoscopic hepatectomy. Methods A total of 120 patients who underwent laparoscopic hepatectomy from January to December 2021 were selected as the research objects, and were divided into ...