2023 Vol. 44, No. 8

Original Articles Basic of Medicine
Analysis of Molecular Characteristics of Mycobacterium Tuberculosis and Factors Associated with Transmission in Yunnan Province
Lianyong CHEN, Xing YANG, Haohao RU, Tao CHEN, Shuangqun YAN, Lin XU
2023, 44(8): 1-7. doi: 10.12259/j.issn.2095-610X.S20230821
Abstract(1960) HTML Cited By (2)
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Objective To understand the distribution characteristics, transmission, and related influencing factors of Mycobacterium tuberculosis genotypes in Yunnan Province, and to provide policy basis for tuberculosis control. Methods Mycobacterium tuberculo...
Polymorphism of 19 Autosomal STR Loci in Achang and De’ang Populations
Guangxing LI, Yunmei ZHANG, Chengjing LIU, Weitao WANG, Kai ZHAO
2023, 44(8): 8-13. doi: 10.12259/j.issn.2095-610X.S20230809
Abstract:
Objective To study the genetic polymorphism of 19 STR loci in unrelated individuals of Achang and Deang ethnic groups in Yunnan Province, China, and to evaluate the forensic value of polymorphism data in ethnic groups. Methods 154 Achang and 405 De...
Screening and Validation of Potential Prognostic Markers of Cervical Squamous Cell Carcinoma Based on The Cancer Genome Atlas Database
Yijun YAN, Hongying YANG, Hongping ZHANG, Zheng LI, Yue JIA, Min ZHAO
2023, 44(8): 14-26. doi: 10.12259/j.issn.2095-610X.S20230808
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Objective To screen and verify the potential prognostic markers of miRNA in cervical squamous cell carcinoma (CESC), and to explore the molecular mechanism of CESC. Methods Using miRNA sequencing data of cervical squamous cell carcinoma tissues and ...
Screening Biomarkers of Astragalus Membranaceus for Hypertensive Ventricular Remodeling Based on Network Pharmacology and Molecular Docking
Hualei DAI, Chengcheng HU, Guimin ZHANG, Siming TAO, Jiankun CHEN
2023, 44(8): 27-36. doi: 10.12259/j.issn.2095-610X.S20230819
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Objective To investigate the mechanisms of Astragalus membranaceus in the treatment of hypertensive ventricular remodeling (VR) based on the principles of network pharmacology and molecular docking. Method The effective components of Astragalus memb...
Effect of Shen-ling-bai-zhu-san on Methamphetamine-Induced Gut Microbiota Change in Mice
Lin XU, Kaicheng GAO, Jie JIA, Yuyang LI, Huawei WANG, Yiqun KUANG, Yu ZHAO
2023, 44(8): 37-43. doi: 10.12259/j.issn.2095-610X.S20230829
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Objective To explore the effect and regulatory mechanism of Shen-ling-bai-zhu-san (SLBZS), a traditional Chinese medicine, on methamphetamine (METH)-induced gut microbiota change in mice. Methods SPF C57BL/6J mice were divided into three groups: sal...
miR-216b-5p Promotes Ferroptosis in Glioblastoma Cells by Targeting NCOA3
Dong WANG, Bibo GAO, Huiying SUN, Denghui LENG, Xiaoping RAN, Wen LIN
2023, 44(8): 44-52. doi: 10.12259/j.issn.2095-610X.S20230805
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Objective To investigate the effect of miR-216b-5p on ferroptosis in glioblastoma cells by targeting NCOA3, with a view to providing new targets for the clinical treatment of glioblastoma. Methods U251 cells were divided into DMSO-treated group, Era...
The Regulatory Mechanism of miR-153-3p on Lumbar Degeneration
Shan YU, Lin XIAO, Dongping GONG, Loufeng LIANG, Anwei LIANG, Xiayi XU, Jie LIN, Huaxin LIANG
2023, 44(8): 53-58. doi: 10.12259/j.issn.2095-610X.S20230807
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objective To investigate the effect of H2O2 on lumbar nucleus pulposus cells and the regulatory mechanism of miR-153-3p on lumbar degeneration. Methods CCK8 was used to detect cell viability in control group and H2O2 group, and flow cytometry was us...
miR-149-5p Regulates Malignant Biological Behavior of Glioma Cells Through MSH5/WNT Signaling Pathway
Yi FENG, Xiaofeng WANG, Ximin BAI, Sheng YAO, Juntao DANG, Yunjie ZHAO, Bing CAI
2023, 44(8): 59-70. doi: 10.12259/j.issn.2095-610X.S20230823
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Objective To explore the mechanism of miR-149-5p regulating the malignant biological behavior of glioma cells through MSH5/Wnt signaling pathway. Methods RT-qPCR was used to detected the expression of miR-149-5p in glioma tissues and cell lines A172...
Analysis of Cardiopulmonary Resuscitation Ability of College Students and Its Influencing Factors
Ying TANG, Xiaoying YANG, Haiyin YANG, Tingting WANG
2023, 44(8): 71-76. doi: 10.12259/j.issn.2095-610X.S20230820
Abstract(2090) HTML Cited By (5)
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Objective To investigate the current situation of CPR knowledge, attitude and practice of college students, analyze the influencing factors, and provide suggestions for CPR health education in colleges and universities. Methods Based on the question...
Clinical Research
Current Status of Drug Treatment for Chronic Heart Failure Patients With Reduced Ejection Fraction in Yunnan: a Single-center Survey
Danhong DONG, Weiwen WANG, Dexia LI, Jun YANG, Na LI, Hang MA, Lin LI
2023, 44(8): 77-84. doi: 10.12259/j.issn.2095-610X.S20230822
Abstract(1403) HTML Cited By (1)
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Objective To investigate the status quo of drug therapy and the factors affecting the standardized drug therapy in patients with heart failure with chronic ejection fraction reduction (HFrEF) in Yunnan province. Methods This is a single-center, pros...
Effects of Estrogen Application Duration in HRT-FET on Pregnancy Outcomes
Zhengmei PAN, Yanzhi WU, Yan Li, Yiyue ZHAO, Xi HU, Yang LIU
2023, 44(8): 85-90. doi: 10.12259/j.issn.2095-610X.S20230804
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Objective To investigate the effect of estrogen application duration on pregnancy outcomes in women of childbearing age during hormone replacement therapy frozen-thawed embryo transfer (HRT-FET). Methods A case-control study was conducted to retrosp...
Efficacy of Neuroendoscopic Surgery in the Treatment of Intraventricular Hemorrhage
Yi GONG, Wenkui YANG, Lin LIU, Dongyu ZHAI
2023, 44(8): 91-94. doi: 10.12259/j.issn.2095-610X.S20230814
Abstract(1643) HTML Cited By (1)
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Objective To evaluate the efficacy of neuroendoscopic surgery in the treatment of intraventricular hemorrhage. Methods The clinical data of 60 cases of intraventricular hemorrhage were analyzed, including 30 cases of endoscopic intracranial hematoma...
Value of Inferior Vena Cava Respiratory Variation in Assessing Volume Responsiveness in Patients with Septic Shock
Xiaoxue LIU, Meiju LI, Jing XIA
2023, 44(8): 95-99. doi: 10.12259/j.issn.2095-610X.S20230816
Abstract(1643) HTML Cited By (1)
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Objective To explore inferior vena cava respiratory variation assessing volume responsiveness in patients with septic shock. Methods A total of 60 patients with septic shock in the Emergency Department of the First Affiliated hospital of a medical u...
Prenatal Ultrasound Observation of Persistent Left Superior Vena Cava with Intracardiac Malformation
Mengxia Tang, Linkun Ta, Yanling Huang, Yongping Lu, Xiangbi Li, Jiafeng Yang
2023, 44(8): 100-104. doi: 10.12259/j.issn.2095-610X.S20230827
Abstract(1831) HTML Cited By (1)
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Objective To investigate the type and pregnancy evolution of persistent fetal left superior vena cava(PLSVC) complicated with intracardiac malformations. Methods The data of 90 fetal cases with persistent left superior vena cava were collected via im...
Clinical Efficacy Study on the Treatment of Post-Stroke Dysphagia Using Acupuncture Combined with Swallowing Therapy Based on the “Central-Peripheral-Central” Closed-Loop Rehabilitation Theory
Sijin HE, Xiaoxia CHEN, Qigang CHEN, Rong ZHAO, Duo LIU, Yingdi LIAO, Daiying LI, Lihua GU
2023, 44(8): 105-109. doi: 10.12259/j.issn.2095-610X.S20230802
Abstract(2059) HTML Cited By (9)
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Objective To observe the clinical efficacy of using acupuncture combined with swallowing therapy device guided by the “central-peripheral-central” closed-loop rehabilitation theory in the treatment of post-stroke dysphagia. Methods 60 patients with ...
Risk Factors of Deep Vein Thrombosis after Soft Tissue Trauma of Lower Extremities
Binbin MA, Ning WANG, Jianping LIU, Kaiquan ZHANG, Yongli GAO, Gaohui LI, Chen ZHANG
2023, 44(8): 110-116. doi: 10.12259/j.issn.2095-610X.S20230817
Abstract(1446) HTML Cited By (2)
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Objective To retrospectively analyze the risk factors of deep vein thrombosis (DVT) in patients with soft tissue trauma of the lower extremities, and to provide reference for the prevention and treatment of DVT. Methods The general clinical data, tr...
Clinical Study on the Effect of Cognitive Behavioral Therapy for Insomnia on Patients with Parkinson’s Disease with Insomnia
Mengshu YANG, Xiaoyun KONG, Huan LI, Yanwei ZOU, Yihao WANG, Ci DONG
2023, 44(8): 117-122. doi: 10.12259/j.issn.2095-610X.S20230806
Abstract(1742) HTML Cited By (3)
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Objective To investigate the effect of cognitive behavioural therapy for insomnia (CBT-I) intervention on sleep quality and mood in Parkinson’s disease patients with insomnia. Methods Parkinson’s disease patients with insomnia who were hospitalized...
Application Value of Nutritional Risk Screening 2002 in Elderly COPD Patients with Dysphagia
Quanyue JI, Mengjing HAN, Kun XU, Tianyun LIU, Hongling SHI, Meng HUANG
2023, 44(8): 123-127. doi: 10.12259/j.issn.2095-610X.S20230815
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Objective To evaluate the incidence of nutritional risk in hospitalized elderly patients with chronic obstructive pulmonary disease complicated with dysphagia with the Nutritional Risk Screening 2002 scale, and to explore the clinical application val...
Application Effect of Whole-process Management Based on Rapid Rehabilitation Combined with Damage Control in Multiple Injuries
Lan Shen, Tongqing Pu, Jiangbo Ding, lunqing Pu, Gang Ma, Tianrui Wang
2023, 44(8): 128-132. doi: 10.12259/j.issn.2095-610X.S20230825
Abstract(1469) HTML Cited By (5)
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Objective To explore the application effect of whole-process management combined with injury control based on rapid rehabilitation in multiple injuries. Methods 43 patients with multiple injuries treated with the traditional specialized treatment mo...
Comparison of the Therapeutic Effects of Two Methods for Removing Black Tooth Stain in Children
Hui DING, Qing ZHOU, Ruzhou FENG, Ni ZHOU, Shinan ZHANG, Juan Liu
2023, 44(8): 133-138. doi: 10.12259/j.issn.2095-610X.S20230801
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Objective To compare the clinical efficacy of using erythritol air-polishing and silica particle polishing for treating extrinsic black tooth stain (EBS) in children. Methods 48 children aged 3-12 years who met the inclusion criteria were selected. ...
Reviews
Research Progress of Perilipin Family of Lipid Droplet Surface Proteins in Cancer
Qun WANG, Yuxin SUN, Haifeng WANG
2023, 44(8): 139-144. doi: 10.12259/j.issn.2095-610X.S20230812
Abstract(2048) HTML Cited By (2)
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With cancer becoming increasingly prevalent and affecting younger populations, there is growing concern about its development and progression. It is worth noting that the global population of obese individuals is also on the rise, and numerous studie...
Research Progress of DNA Methylation and Schizophrenia
Wensa YIN, Yumei LU, Jinlian TONG, shengjie NIE, Ye RUAN
2023, 44(8): 145-150. doi: 10.12259/j.issn.2095-610X.S20230811
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Schizophrenia is a mental disorder characterized by significant abnormalities in cognition, thinking, emotion, and behavior. It is one of the most common severe mental disorders and causes serious distress to individuals, families, and society. In re...
Teaching Research
Exploratory Practice of Multidimensional Evaluation System for Target-oriented Clinical Teaching Abilities
Rui LI, Qiaofen LI, Anshu XU, Minming LIN
2023, 44(8): 151-155. doi: 10.12259/j.issn.2095-610X.S20230803
Abstract(2397) HTML Cited By (1)
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Objective To construct a multi-dimensional evaluation system for teachers’ clinical teaching ability and explore its effectiveness in improving teachers’ clinical teaching ability. Methods From October 2019 to September 2022, 100 teachers for underg...
Analysis of Single and Multiple Latent Categories of Satisfaction with Online and Offline Teaching for Medical Students Studying in China
Xia XIAO, Xiaoxiao SONG, Xianhui GUO, Yujiao ZHANG, Yongna ZHAO, Yun LIU, Qian LI, Chunrui LUO, Fanwei QU
2023, 44(8): 156-161. doi: 10.12259/j.issn.2095-610X.S20230826
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Objective This study aims to investigate the differences in satisfaction with online and offline teaching services among international medical students in China and to explore the influencing factors. The ultimate goal is to contribute to the high-qu...
Nursing Forum
Effects of Narrative Nursing on Psychological Distress and Quality of Life in Patients with Gastrointestinal Malignancies
Yunhui ZHANG, Yang SUN, Xieqiao HE, Dezhi TAO, Fameng LUO, Haiyan ZHANG
2023, 44(8): 162-166. doi: 10.12259/j.issn.2095-610X.S20230810
Abstract(1945) HTML Cited By (9)
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Objective To investigate the effects of the psychological distress and quality of life of patients with gastrointestinal malignant tumors, and provide reference for clinical care. Methods 80 patients with gastrointestinal malignancies were randomly ...
Effect of Narrative Nursing on Negative Emotions,Sleep Quality and Nursing Satisfaction of RSA Patients
Junfang YANG, Lantian LOU, Fayan ZHENG, Yunna LI, Jiamei SONG
2023, 44(8): 167-171. doi: 10.12259/j.issn.2095-610X.S20230818
Abstract(1790) HTML Cited By (4)
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Objective To explore the effect of narrative nursing on adverse psychological reactions and sleep quality of RSA patients, and to evaluate its clinical application effect and value. Methods 240 RSA patients in the Department of Reproductive Medicine...
Impact of O2O Health Education Based on Propensity Score Matching on Moderate to Severe Acne Vulgaris
Dandan ZHAN, Zhou ZHOU, Xiongshan SUN, Xia XU
2023, 44(8): 172-176. doi: 10.12259/j.issn.2095-610X.S20230828
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Objective To explore the effect of O2O health education based on propensity score matching method on moderate and severe acne vulgaris. Methods A retrospective analysis was conducted on the patients with moderate to severe acne vulgaris treated in t...
Mental Health Status of Emergency Rescue Nurses in Yunnan Province
Yunshan LIAO, Shuangshuang WANG, Lijuan YIN, Yuting ZHENG
2023, 44(8): 177-184. doi: 10.12259/j.issn.2095-610X.S20230824
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Objective To understand the mental health status and influencing factors of nurses participating in out-of-hospital emergency rescue in Yunnan province, and to provide reference for formulating targeted mental health intervention programs for emergen...