2024 Vol. 45, No. 2

Expert Forum
Research Progress of Artificial Intelligence in the Diagnosis and Treatment of Anorectal Diseases
Yiwen ZHANG, Ximing WANG, Zilong LI, Xinzhang ZHANG, Changxian CHEN, Weijun LIU, Zhenyong ZHANG
2024, 45(2): 1-6. doi: 10.12259/j.issn.2095-610X.S20240201
Abstract(1566) HTML PDF(45) Cited By (1)
Abstract:
In the past 20 years, the development of artificial intelligence has made rapid progress, and it is increasingly applied in the medical field, including medical image-assisted diagnosis and treatment, health management, disease risk prediction and so...
Original Articles Basic of Medicine
Role of HK2 and VDAC1 in Diacetylmorphine-induced Cardiomyocyte Apoptosis
Jinling XIAO, Yaling GUAN, Sensen ZHU, Mengjie ZHUANG, Liping SU, Hongwei PU
2024, 45(2): 7-13. doi: 10.12259/j.issn.2095-610X.S20240202
Abstract(957) HTML PDF(17) Cited By (1)
Abstract:
Objective To investigate the role of HK2 and VDAC1 in diacetylmorphine-induced cardiomyocyte apoptosis. Methods A dose-escalation method was used to establish a rat model of diacetylmorphine addiction. Forty SD rats were randomly divided into three ...
Correlation of KRAS Gene 3′ UTR Polymorphisms with Cervical Cancer and Cervical Intraepithelial Neoplasia in Chinese Han Population in Yunnan Province
Ni GUO, Cheng ZHANG, Chao HONG, Weipeng LIU, Yufeng YAO, Zhiling YAN
2024, 45(2): 14-22. doi: 10.12259/j.issn.2095-610X.S20240203
Abstract(1174) HTML PDF(22) Cited By (1)
Abstract:
Objective To investigate the correlation between rs712 and rs7973450 located at the 3′ UTR region of the KRAS gene and the risk of cervical cancer (CC) and cervical intraepithelial neoplasia (CIN) in Chinese Han population in Yunnan province. Method...
Effects and Mechanisms of Xueshuantong on the Cognitive Function and Abnormal Neural Excitability in Mice with Alzheimer’ s Disease
Hui LIU, Guoji YAN, Jia WU, Dan WANG, YANGYanbin XI, Shanshan LI
2024, 45(2): 23-31. doi: 10.12259/j.issn.2095-610X.S20240204
Abstract(1082) HTML PDF(16) Cited By (1)
Abstract:
Objective To explore the possible effects and the underlying molecular mechanisms of xueshuantong [The main active component is panax notoginseng (PNS)] on the cognitive function and neural excitability of mice with Alzheimer’ s disease (AD). Method...
Study on the Relationship Between OAT1 Expression and Renal Osteodystrophy in Rats with Chronic Renal Failure
Wenjuan SHEN, Wenxin LIANG, Qing LI, Hongfang XU, weiqin ZHANG, Haixin LI
2024, 45(2): 32-38. doi: 10.12259/j.issn.2095-610X.S20240205
Abstract(925) HTML PDF(8)
Abstract:
Objective To investigate the changes of OAT expression in bone cells in chronic renal failure (CRF)and involved mechanism, and to explore the effect of OAT expression on bone metabolism. Methods Randomly divide the rats into a control group (n=6)and...
Effect of MSC-exo,a New Cell Delivery Tool,on Gene Delivery and Proliferation of Pancreatic Cancer
Lei ZHU, Ruixue LI, Changlei BAO, Chenchen HUANG, Shuxin LIANG, Zhenlin ZHAO, Hong ZHU
2024, 45(2): 39-48. doi: 10.12259/j.issn.2095-610X.S20240206
Abstract(1117) HTML PDF(11)
Abstract:
Objective To observe the effect of a new cell delivery tool (MSC exo) on the proliferation of pancreatic cancer by transferring targeted genes. Methods Transmission Electron Microscope (TEM) and Nanoparticle Tracking Analysis(NTA) were used to ident...
Effects of Ferroptosis Inhibitor KIF20A on Biological Behavior and Ferroptosis of Esophageal Carcinoma Cells
Maimaitizunong Rezeye, Xiujuan LI, Ling LIU, Hui LI
2024, 45(2): 49-56. doi: 10.12259/j.issn.2095-610X.S20240207
Abstract(879) HTML PDF(18) Cited By (1)
Abstract:
Objective To investigate the expression of KIF20A in ESCC and its effect on Eca109 cell biological behavior and ferroptosis. Methods The expression of KIF20A in ESCC was predicted by bioinformatics analysis. KIF20A knockdown /overexpression Eca109 c...
Clinical Research
A Meta-analysis of the Risk of Secondary Infection of Tocilizumab in the Treatment of COVID-19
Ya LUO, Yanting YU, Xue ZHANG, Zhongjuan WANG
2024, 45(2): 57-64. doi: 10.12259/j.issn.2095-610X.S20240208
Abstract(1071) HTML PDF(9)
Abstract:
Objective Meta-analysis was conducted to assess the risk of secondary infection caused by tocilizumab (TCZ) in the treatment of Corona Virus Disease 2019 (COVID-19), in order to provide an evidence-based basis for the safety of tocilizumab in patient...
A Meta-analysis of the Effect of Adjuvant Probiotics in Patients with Osteoporosis
Leijing RAN, Shaohua WANG, Lintong LI, Li GUI
2024, 45(2): 65-76. doi: 10.12259/j.issn.2095-610X.S20240209
Abstract(1078) HTML PDF(15)
Abstract:
Objective Systematically evaluate the efficacy of probiotics in treating osteoporosis. Methods Computer search of Cochrane Library, Web of Science, PubMed, Embase, VIP, CNT and Wanfang data knowledge service platform, the search time limit of August ...
The Association of Intestinal Flora Metabolite TMAO with Non-alcoholic Fatty Liver Disease
Yuanyuan LI, Yaxian SONG, Yushan XU, Xiaofu ZENG, Hui YUAN, Zhao XU, Yan JIANG
2024, 45(2): 77-84. doi: 10.12259/j.issn.2095-610X.S20240210
Abstract(1634) HTML PDF(22)
Abstract:
Objective To explore the role of TMAO from gut microbiota in non-alcoholic fatty liver disease (NAFLD), we detected the serum level of TMAO and its precursor metabolites in NAFLD, as well as the expression level of Eubacterium rectum, Bacteroidetes m...
Current Situation of Health Service Needs and Utilization among Six Zhiguo Ethnic Minority Groups in Yunnan Province
Jie CHEN, Xinping WANG, Jiayi XIONG, Chunming MA, Yuan HUANG, Rui DENG, Feng JIAO
2024, 45(2): 85-93. doi: 10.12259/j.issn.2095-610X.S20240211
Abstract(1355) HTML PDF(19)
Abstract:
Objective To investigate the need for and utilization of health services among six Zhiguo ethnic minority groups in Yunnan Province, aiming to provide further evidence for the improvement of healthcare. Methods Using stratified random sampling, 1921...
Clinical Significance of Ultrasound Signs Combined Diagnosis in Acute Appendicitis of Children
Min TANG, Xiaoli SHANG
2024, 45(2): 94-98. doi: 10.12259/j.issn.2095-610X.S20240212
Abstract(944) HTML PDF(5) Cited By (2)
Abstract:
Objective To explore the characteristics and diagnostic significance of ultrasound signs in the diagnosis of acute appendicitis in children. Methods This study focused on 81 children with acute appendicitis and divided them into two groups based on ...
Clinical Efficacy of Abdominal Ultrasound-guided Endoscopic Retrograde Appendicitis Therapy for Acute Uncomplicated Appendicitis
Siyun LI, Zanyou YAN, Zan SHENG, Jieyu LIU, Jihua HUANG, Zhiping GUO, Yuping JI, Zhongjian LIU, Fan ZHANG
2024, 45(2): 99-104. doi: 10.12259/j.issn.2095-610X.S20240213
Abstract(965) HTML PDF(11) Cited By (1)
Abstract:
Objective To compare the clinical efficacy of abdominal ultrasound-guided endoscopic retrograde appendicitis therapy (ERAT) with laparoscopic appendectomy (LA) for acute uncomplicated appendicitis using propensity score matching. Methods The clinica...
Analysis on Nutritional Status of Vitamin D Among Adults of 6 Ethnic Minority Groups Native to Yunnan Province
Nan ZHANG, Yanling YANG, Qingqing WAN, Jiang ZHAO, Min PENG, Xiao ZHU, Zhitao LIU, Qiang ZHANG
2024, 45(2): 105-111. doi: 10.12259/j.issn.2095-610X.S20240214
Abstract(1779) HTML PDF(14) Cited By (1)
Abstract:
Objective To assess the nutritional status of vitamin D and associated factors among adults of six ethnic minority groups native to Yunnan Province, and provide evidence for policy making. Methods Between May 2019 and August 2020, a total of 690 adu...
Analysis of Breastfeeding Duration and Influencing Factors of Children Aged 0-5 Years in Yunnan Province
Zhonghua AI, You HUANG, Xianglong ZHU, Yanchun GAO, Songyuan TANG, Rui PAN
2024, 45(2): 112-116. doi: 10.12259/j.issn.2095-610X.S20240215
Abstract(1498) HTML PDF(20) Cited By (1)
Abstract:
Objective To understand the current situation of breastfeeding duration in children aged 0-5 years in Yunnan Province, and to explore the influencing factors of breastfeeding duration. Methods Using the data of the 6th National Health Service Survey...
Evaluation of Cardiac Toxicity of Anthracyclines in Children with Acute Leukemia Based on Tei Index
Xuemei CHEN, Pin GUO, Liufang CHUAN, Zi WANG, Xuejiao LI, Wenji HE
2024, 45(2): 117-122. doi: 10.12259/j.issn.2095-610X.S20240216
Abstract(867) HTML PDF(12)
Abstract:
Objective To apply ultrasound to monitor cardiac function changes after anthracycline exposure in children with acute leukemia, in order to obtain the indicators of early changes in their cardiac function. Methods Children with acute leukemia from 2...
Analysis of Clinical Characteristics and Death Risk Factors in Patients with Community-acquired Pneumonia Complicated with Diabetes
Jianfang MA, Xiaoling HUANG, Yanhua LI, Di MA, Kaifen YUAN
2024, 45(2): 123-130. doi: 10.12259/j.issn.2095-610X.S20240217
Abstract(1383) HTML PDF(14) Cited By (1)
Abstract:
Objective To explore the clinical characteristics and risk factors of death during hospitalization in patients with community-acquired pneumonia(CAP) complicated with diabetes mellitus(DM). Methods A retrospective analysis was performed on 566 patie...
Comparison of Four Methods in the Diagnosis of Bone Tuberculosis
Xiaoqin LI, Zhiqiang MA, Nan TIAN, Wei CHEN, Caixin LI, Min ZHOU
2024, 45(2): 131-135. doi: 10.12259/j.issn.2095-610X.S20240218
Abstract(960) HTML PDF(14)
Abstract:
Objective To compare the diagnostic value of smear acid-fast staining, TB-DNA, X-pert MTB/RIF and culture of Mycobacterium tuberculosis. Methods Four methods were used to detect the perifocal pus of the patients with bone destruction in orthopaedics...
Effect of Nicorandil on Inflammation-related Markers after PCI Intervention in Patients with Acute Coronary Syndromes
Xiaodong ZHANG, Nan NIU, Ying LIU, Jiajie MEI, Zhaohong GENG, Hongyan WANG
2024, 45(2): 136-140. doi: 10.12259/j.issn.2095-610X.S20240219
Abstract(915) HTML PDF(12) Cited By (1)
Abstract:
Objective To investigate the effects of treatment with nicorandil after Percutaneous Coronary Intervention (PCI) in patients with Acute Coronary Syndrome (ACS) on inflammation-related markers, and to assess its effects on vascular endothelial functio...
A Comparative Study of Three Methods of Preventing Intrauterine Adhesions after HEOS
Liyan MENG, Junli GAO, Chunlin LI, Jie NIU, Yan SUN, Chaoqun WANG
2024, 45(2): 141-147. doi: 10.12259/j.issn.2095-610X.S20240220
Abstract(1401) HTML PDF(7) Cited By (1)
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Objective To compare the efficacy of three different methods in the prevention of adhesion after the HEOS system for different degrees of intrauterine adhesions. Methods 284 patients with mild, moderate and severe intrauterine adhesions, who were tr...
Effects of Different Virulence Types of Helicobacter Pylori on Gastric Micro-environment
Xiaoqing ZHAO, Jiaxin XIAO, Yong LIN, Jianfeng ZHANG, Wenhui WANG, Wenjie ZHANG
2024, 45(2): 148-152. doi: 10.12259/j.issn.2095-610X.S20240221
Abstract(930) HTML PDF(15) Cited By (2)
Abstract:
Objective To observe the effects of different virulence types of Helicobacter pylori on pepsin and inflammatory factors. Methods 110 patients admitted from December 2021 to March 2023 were collected and divided into HP positive group(n=79) and HP n...
Research Progress on the Anti-tumor Activity and Mechanism of Narciclasine
Min YANG, Qiqi LIN, Dandan LIU, Hongyu ZHOU
2024, 45(2): 153-159. doi: 10.12259/j.issn.2095-610X.S20240222
Abstract(1244) HTML PDF(23)
Abstract:
Narciclasine(NCS), a hymenocallis littoralis alkaloid extracted from the bulbs of the genus Narcissus in the Lycoriaceae family, has been proven to have significant anti-tumor activity against a variety of tumor cells. The antitumor mechanisms of NCS...
Reviews
Research Progress on Paradoxical Extraintestinal Manifestations of Biologics in the Treatment of Inflammatory Bowel Disease
Zhangqin LI, Qi HUANG, Yinglei MIAO
2024, 45(2): 160-165. doi: 10.12259/j.issn.2095-610X.S20240223
Abstract(1125) HTML PDF(23)
Abstract:
Inflammatory Bowel Diseases (IBD) is a class of genetically related diseases caused by multiple genes and environmental factors that accelerate the disturbance of the immune-gut-microbiome axis. Lesions often involve multiple organs and systems. Biol...
Application of CAD/CAM Technology in the Teaching of Inlay Production
Yingying XIANG, Hao HUANG, Xuelin LI, Zhigang XIA, Kaiwen DUAN, Fei SONG
2024, 45(2): 166-169. doi: 10.12259/j.issn.2095-610X.S20240224
Abstract(1110) HTML PDF(9)
Abstract:
Objective To study the application value of CAD/CAM technology in the teaching of inlay manufacturing. Methods A total of 60 undergraduates interned in the Department of Stomatology, Yan’ an Hospital, Kunming Medical University were randomly divided...
Nursing Forum
Investigation and Analysis of Health Education Needs of Patients Undergoing Radiofrequency Ablation of Atrial Fibrillation Based on Kano Model
Zilin MA, Wenni MA, Yi MA, Yongshi FAN, Yan JIN, Ying HUANG
2024, 45(2): 170-176. doi: 10.12259/j.issn.2095-610X.S20240225
Abstract(917) HTML PDF(7)
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Objective To investigate the health education needs of patients undergoing radiofrequency ablation of atrial fibrillation and to provide a basis for the formulation of targeted health education programs. Methods A self-designed questionnaire on the ...
Application of Caregiver Health Education Based on Timing Theory in the Postoperative Care of Elderly Industrial Hip Arthroplasties
Ling HUANG, Qichuan HU, Jinxiu DUAN, Binghui ZHU, Peipei CUI, Youmin YU
2024, 45(2): 177-183. doi: 10.12259/j.issn.2095-610X.S20240226
Abstract(1018) HTML PDF(11) Cited By (2)
Abstract:
0bjective To explore the effectiveness of caregivers based on health education under the guidance of timing theory in the nursing of elderly patients after hip replacement. Methods By convenient sampling method, eighty elderly patients undergoing hi...
Current Situation and Influencing Factors of Nurses’ Ability to Respond to Public Health Emergencies in Yunnan Province
Yong DONG, Xingqiong GU, Shuaizhong CAI, Jiao YANG, Haiyin YANG, Qiongyao GUAN
2024, 45(2): 184-190. doi: 10.12259/j.issn.2095-610X.S20240227
Abstract(1374) HTML PDF(15)
Abstract:
Objective To explore the current situation of nurses’ emergency response ability of public health emergencies and analyze its influencing factors in Yunnan province, so as to provide empirical basis for the construction of emergency response ability ...