2021 Vol. 42, No. 2
2021, 42(2): 18-22.
doi: 10.12259/j.issn.2095-610X.S20210216
Abstract:
Objective To explore a method for the synthesis of alkaloid-likes from Genipin by reductive amination is reported. Methods The reduction of Genipin and amines in the presence of sodium cyanoborohydride: after the methanol solution of Genipin and ary...
2021, 42(2): 1-5.
doi: 10.12259/j.issn.2095-610X.S20210202
Abstract:
Objective To discuss whether the neuroprotective effect of dexmedetomidine (DEX) against traumatic brain injury (TBI) is related to the inhibition of neuronal apoptosis and whether it is involved in SIRT1 signaling pathway. Methods SD rats were rando...
2021, 42(2): 6-12.
doi: 10.12259/j.issn.2095-610X.S20210222
Abstract:
Objective To explore the application value of Ultrasound Targeted Microbubble Destruction (UTMD) with IL-6 monoclonal antibody combined with different ultrasonic irradiation intensity in myocardial ischemia-reperfusion injury (MI/RI). Methods Ninety ...
2021, 42(2): 13-17.
doi: 10.12259/j.issn.2095-610X.S20210225
Abstract:
Objective To determine the content of five nucleosides in Periplaneta Americana L. extract by HPLC. Methods We did degreasing the Periplaneta Americana L.powder with petroleum ether, ultrasonic extraction of 65% ethanol as solvent, acetonitrile diss...
2021, 42(2): 23-28.
doi: 10.12259/j.issn.2095-610X.S20210206
Abstract:
Objective To elucidate the pathogenic role of phospholipase C epsilon 1 (PLCE1) in neuropathic pain of rats with type 1 diabetes by observing the effect of intrathecal injection of exoenzyme C3 (a RhoA inhibitor) on the activity of PLCE1 and inflamma...
2021, 42(2): 29-32.
doi: 10.12259/j.issn.2095-610X.S20210232
Abstract:
Objective Study the chemical compounds from the plants of P. yunnanensis and find its bioactive constituents. Methods The compounds were extracted by ethyl acetate and isolated by column chromatography on silica gel and Sephadex LH-20. 1H NMR, 13CNMR...
2021, 42(2): 33-37.
doi: 10.12259/j.issn.2095-610X.S20210226
Abstract:
Objective To analyze the status of malnutrition for Dulong residents aged 6-80 years in Gongshan county of Yunnan in 2006 and to study it's influencing factors. Methods By using a stratified cluster sampling method, 460 Dulong nationality residents ...
2021, 42(2): 75-80.
doi: 10.12259/j.issn.2095-610X.S20210230
Abstract:
Objective To explore the initial clinical effect of posterior unilateral decompression and fixation for single-segment cervical spondylosis. Methods We retrospectively analyzed the clinical data of 26 patients with cervical spondylotic radiculopath...
2021, 42(2): 118-123.
doi: 10.12259/j.issn.2095-610X.S20210207
Abstract:
Objective To investigate the status of insomnia and the related influencing factors among patients with chronic pain in department of pain. Methods A total of 431 patients were recruited from department of pain and a questionnaire survey was perfor...
2021, 42(2): 137-139.
doi: 10.12259/j.issn.2095-610X.S20210205
Abstract:
Objective To investigate the effects of MHI on diaphragm movement and BI Index in stroke patients. Methods From 2017 to 2018, 40 patients with stroke were randomly assigned into treatment group and control group equally. The control group received ...
2021, 42(2): 38-42.
doi: 10.12259/j.issn.2095-610X.S20210212
Abstract:
Objective To exlpore the application value of Color Doppler Flow Imaging (CDFI) and superb microvascular imaging (SMI) combined with self-defined scoring in the evaluation of renal perfusion in chronic kidney disease (CKD). Methods CDFI and SMI were ...
2021, 42(2): 43-48.
doi: 10.12259/j.issn.2095-610X.S20210221
Abstract:
Objective To investigate the impact of propofol combined with Dexmedetomidine (Dex) or midazolam on the clinical effect, postoperative cognitive function and adverse reactions in elderly's painless gastrointestinal endoscopy. Methods Three hundreds ...
2021, 42(2): 49-53.
doi: 10.12259/j.issn.2095-610X.S20210214
Abstract:
Objective To investigate the clinical application value of anti-dsDNA antibody, complement C3 and other laboratory indicators in patients with systemic lupus erythematosus (SLE) with renal injury. Methods The clinical data of 296 SLE patients were re...
2021, 42(2): 54-63.
doi: 10.12259/j.issn.2095-610X.S20210211
Abstract:
Objective To study the metabolomic differences of serum and feces between patients with type 2 diabetes and healthy people, and analyze the correlation between different metabolites and type 2 diabetes. Methods From January 2018 to March 2019, 53 pat...
2021, 42(2): 64-69.
doi: 10.12259/j.issn.2095-610X.S20210201
Abstract:
Objective To analyse the clinical features of Rhupus syndrome. Methods The medical records of 21 Rhupus syndrome patients who were admitted to the Second Affiliated Hospital of Kunming Medical University from 2015 to 2019 were analysed retrospectivel...
2021, 42(2): 70-74.
doi: 10.12259/j.issn.2095-610X.S20210229
Abstract:
Objective To analyze the diagnostic value of Coronary Computed tomography angiography (CCTA)combined with rest CT myocardial perfusion (CT-MPI) in patients after percutaneous coronary intervention (PCI). Methods Twenty-two patients after PCI were sel...
2021, 42(2): 81-85.
doi: 10.12259/j.issn.2095-610X.S20210217
Abstract:
Objective To observe the clinical effect of swallowing dysfunction training on neonates with swallowing disorder. Methods We selected 140 cases of pediatric NICU ward in March 2018 to July 2018, randomly divided them into intervention group and cont...
2021, 42(2): 86-90.
doi: 10.12259/j.issn.2095-610X.S20210215
Abstract:
Objective To inverstigate the association between methylenetetrahydrofolate reductase (MTHFR)677C > T gene polymorphism and pregnancy induced hypertension in pregnant women. Methods Ninety HDCP patients who underwent prenatal examination in Yan'an...
2021, 42(2): 91-95.
doi: 10.12259/j.issn.2095-610X.S20210224
Abstract:
Objective To evaluate the clinical effect of flexible ureteroscope lithotripsy on solitary and non-solitary renal calculi. Methods We collected 20 cases of solitary renal calculi and 48 cases of non-solitary renal calculi in the second affiliated ho...
2021, 42(2): 96-102.
doi: 10.12259/j.issn.2095-610X.S20210218
Abstract:
Objectives To observe the effect of renal sympathetic denervation on acute ventricular remodeling in SHR. Methods This experiment enrolled 50 male rats of SHR, the average weight was (265±12) g. According to the difference of intervention way, they ...
2021, 42(2): 103-107.
doi: 10.12259/j.issn.2095-610X.S20210219
Abstract:
Objective To explore the clinical value of B-lynch suture combined with intrauterine gauze packing in the treatment of refractory postpartum hemorrhage in hospitals in underdeveloped areas. Methods A comparative study was conducted on 108 cases of re...
2021, 42(2): 108-112.
doi: 10.12259/j.issn.2095-610X.S20210223
Abstract:
Objective To evaluate the effect of continuous infusions of dexmedetomidine on the pediatric anesthesia emergence delirium (PAED)after general anesthesia in pediatric patients undergoing hip surgery. Methods Seventy children, ASA class I-II, aged 3~...
2021, 42(2): 113-117.
doi: 10.12259/j.issn.2095-610X.S20210231
Abstract:
Objective To investigate the clinical application value of modified Beger operation. Methods The clinical data of 59 patients with chronic pancreatitis, benign and low-grade malignant tumor of pancreatic head treated by surgery from January 2014 to ...
2021, 42(2): 124-129.
doi: 10.12259/j.issn.2095-610X.S20210203
Abstract:
Objective To explore the effective treatment for osteoporotic delayed vertebral collapse. Methods Between March 2013 and March 2018, a total of 46 patients with osteoporotic delayed vertebral fracture with no or mild neurological symptoms were enroll...
2021, 42(2): 130-136.
doi: 10.12259/j.issn.2095-610X.S20210204
Abstract:
Objective To investigate the changes of serum cystatin C(Cys C), β 2-microglobulin(β 2-MG), monocyte chemoattractant protein-1(MCP-1)and angiotension Ⅱ(ANG Ⅱ)levels in patients with chronic renal failure(CRF), and analyze the relationship between the...
2021, 42(2): 140-146.
doi: 10.12259/j.issn.2095-610X.S20210220
Abstract:
Atopic dermatitis(AD)also known as atopic eczema, Besnier prurigo diathesique or hereditary allergic eczema, is a skin disease characterized by eczema-like skin lesions, severe itching and obvious "atopy" in oneself or his family. In recent years, th...
Atopic dermatitis(AD)also known as atopic eczema, Besnier prurigo diathesique or hereditary allergic eczema, is a skin disease characterized by eczema-like skin lesions, severe itching and obvious "atopy" in oneself or his family. In recent years, th...
2021, 42(2): 147-152.
doi: 10.12259/j.issn.2095-610X.S20210208
Abstract:
The main components of cannabis with medicinal value are Δ9-tetrahydrocannabinol(Δ9-THC)and cannabidiol(CBD), of which CBD cannot directly activate cannabinoid type 1 receptor(CB1R)and cannabinoid type 2 receptors. Body(CB2R)does not have psychoactiv...
The main components of cannabis with medicinal value are Δ9-tetrahydrocannabinol(Δ9-THC)and cannabidiol(CBD), of which CBD cannot directly activate cannabinoid type 1 receptor(CB1R)and cannabinoid type 2 receptors. Body(CB2R)does not have psychoactiv...
2021, 42(2): 153-157.
doi: 10.12259/j.issn.2095-610X.S20210210
Abstract:
Methamphetamine is a serious threat to public health and safety of mental excitatory drugs. Long-term abuse of METH will cause obvious neuronal injury and neurotoxicity. Oxidative stress, mitochondrial metabolic damage and neuroinflammation play impo...
Methamphetamine is a serious threat to public health and safety of mental excitatory drugs. Long-term abuse of METH will cause obvious neuronal injury and neurotoxicity. Oxidative stress, mitochondrial metabolic damage and neuroinflammation play impo...
2021, 42(2): 158-161.
doi: 10.12259/j.issn.2095-610X.S20210213
Abstract:
Pathological pain refers to the pain caused by various diseases, which can be divided into inflammatory pain, neuropathic pain, cancer pain and so on. Due to the complexity of its pathogenesis and the specificity of clinical features, the analgesic e...
Pathological pain refers to the pain caused by various diseases, which can be divided into inflammatory pain, neuropathic pain, cancer pain and so on. Due to the complexity of its pathogenesis and the specificity of clinical features, the analgesic e...
2021, 42(2): 162-166.
doi: 10.12259/j.issn.2095-610X.S20210228
Abstract:
Objective To explore the standardization process of laparoscopy operation training in undergraduate teaching. Methods A total of 90 undergraduate interns from the First Affiliated Hospital of Kunming Medical University from January 01, 2017 to June...
2021, 42(2): 167-172.
doi: 10.12259/j.issn.2095-610X.S20210227
Abstract:
Objective To explore the application of scenario simulation nutrition intervention to improve the cognitive level of children with diabetes of different ages. Methods From January 2018 to December 2019 120 school-age children with diabetes were divi...
2021, 42(2): 173-178.
doi: 10.12259/j.issn.2095-610X.S20210209
Abstract:
Objective To observe the incidence of complications in patients with ultrasound-guided PICC catheterization and explore the influencing factors. Methods The clinical data of 536 patients with ultrasound-guided PICC catheterization were retrospectivel...