2021 Vol. 42, No. 5

Original Articles Basic of Medicine
The Analysis of Incidence Trend of Tumor in Shilin County, Kunming City from 2016 to 2018
Qing-huan YANG, Hai-liang RAN, Jin-chun YU, Yan-qin RUAN, Ying CHEN
2021, 42(5): 54-58. doi: 10.12259/j.issn.2095-610X.S20210510
Abstract(3739) HTML PDF(12)
Abstract:
Objective To analyze the incidence rate and epidemiological trend of tumor in Shilin county, Kunming city from 2016 to 2018. Methods The data of tumor and demographics were collected form Shilin county surveillance system from 2016 to 2018. The cru...
Antimicrobial and Antitumor Zingiberaceae Diterpene Derivatives Prepared by Structure Modification
Jie-chen QIN, Xiao-fei ZUO, Cheng ZOU, Cheng-jie TUO, Ke-tao ZHANG, Xiao-mei ZHANG, Qing ZHAO
2021, 42(5): 1-5. doi: 10.12259/j.issn.2095-610X.S20210501
Abstract(3110) HTML PDF(24)
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Objective Coronarin E, a diterpenoid was utilized to synthesize bioactive derivatives. Method Coronarin E underwent SeO2 oxidation, acylation and photosensitized oxidation, two butenolide derivatives were obtained, which were subjected to antimicrobi...
Effects of Different Doses of Gastrodin on Conditioned Place Preference and Microglia Activation in Hippocampus of Methamphetamine Dependent Rats
Ting-na ZHU, Peng-liang LIU, Wen-juan DONG, Hao YU, Ya-mei WU, Zhao-kui HUANG, Shi-jun HONG, Yong-na ZHAO
2021, 42(5): 6-11. doi: 10.12259/j.issn.2095-610X.S20210502
Abstract(4407) HTML PDF(28)
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Objective To study the effects of different dosages of gastrodin on conditioned place preference and hippocampal microglia activation in methamphetamine (Meth)-dependent rats. Methods Meth dependent CPP model was established by intraperitoneal inject...
Periodontal Ligament Stem Cell BMP-2-PSH Composite Membrane in Repairing Alveolar Bone Defect in New Zealand Rabbits
Jing ZHOU, Ping XIONG, Chao-feng LIU, Li-qiong CHEN, Yong-hui ZHANG, Ke SHI, Yan NIE, Yan LIU
2021, 42(5): 12-17. doi: 10.12259/j.issn.2095-610X.S20210503
Abstract(3154) HTML PDF(29)
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Objective It is planned to build a New Zealand rabbit periodontal defect model and determine the biological safety of hPDLSCs-BMP-2-PSH membrane and its in vivo osteogenic repair effect. Methods After confirming that the BMP-2-PSH membrane was not cy...
The Effect of Silencing of UBE2C Gene on the Proliferation and Migration of Human Gastric Cancer AGS Cells
Lan YANG, Xiao JIA, Yi-tong JIANG, Qi CUI, Guang-ci LIU, Ying-hong HE
2021, 42(5): 18-23. doi: 10.12259/j.issn.2095-610X.S20210504
Abstract(3988) HTML PDF(27)
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Objective To investigate the influence of the silence of UBE2C gene on the gastric cancer AGS cells proliferation and migration of human. Methods Using RNA interference technology, the expression vector of UBE2C silenced lentivirus was transfered int...
The Expression and Significance of Eukaryotic Translation Initiation Factor-5A2 in Intrahepatic Cholangiocarcinoma
Shao-hua YANG, Zhou-Jun LIAO, Sheng HU, Mao-lin HONG, Zhi-Mei SONG, Qun WEI, Xiao-wen ZHANG
2021, 42(5): 24-28. doi: 10.12259/j.issn.2095-610X.S20210505
Abstract(3504) HTML PDF(21)
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Objective To study the expression of eukaryotic translation initiation factor 5A2 (eIF5A2) in intrahepatic cholangiocarcinoma and its correlation with nerve invasion and peripheral adipose tissue infiltration. Methods Paraffin sections from 156 patie...
The Electroencephalogram and Analysis of MPTP-Induced Tree Shrew Model for Parkinson's Disease
Bo LI, Jian-lin JIAO, Chuan-yi ZHANG, Ya-qiong QIU, Hao GUO, Huai-chang SUN, Zhi-cheng YU
2021, 42(5): 29-34. doi: 10.12259/j.issn.2095-610X.S20210506
Abstract(4075) HTML PDF(17)
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Objective To study the characteristics of cortical electroencephalogram (EEG), power spectrum and mapping in tree shrew model for Parkinson’ s disease (PD). Methods Ten common-level Burmese adult tree shrews were selected and randomly divided into a ...
Traditional Chinese Medicine Transcriptome Analysis of Characteristic Distribution of Scorpion Genes in Venomous Glands
Hong-fei ZHANG, De-long GE, Xiao-fei HUANG, Di MEI, Li GUO, Yi-rong WANG, Hai-mei LI, Tong-yi SUN, Guang-tao JIA, Wen-hui LI
2021, 42(5): 35-40. doi: 10.12259/j.issn.2095-610X.S20210507
Abstract(3613) HTML PDF(17)
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Objective To obtain the transcriptome dataset of Buthus martensii. Methods Taking the characteristic Buthus martensii in Linyi area of Shandong Province as the research object, the second-generation high-throughput sequencing platform Illumina HiSeq ...
Quality of Life and Its Influencing Factors in Han Nationality Patients with Polycystic Ovary Syndrome
Zheng-jiao DONG, Wen-que ZHANG, Lin-na YANG, Xue-hui HUANG, Yi-yan ZHANG, Wen-yang ZHANG, Jing-jing ZHANG
2021, 42(5): 41-47. doi: 10.12259/j.issn.2095-610X.S20210508
Abstract(3887) HTML PDF(15)
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Objective To investigate and evaluate the quality of life and its influencing factors in Han nationality patients with PCOS. Methods Convenient sampling methods were used.163 Han patients with PCOS who were diagnosed in gynaecological out-patient cli...
Feasibility Analysis of the NOSAS Score as A Screening Tool for Obstructive Sleep Apnea in the Physical Examination Population
Wen-hui DONG, Xu ZOU, Zhong GONG, Li-qin SU, Hui-ying LI, Han ZHANG
2021, 42(5): 48-53. doi: 10.12259/j.issn.2095-610X.S20210509
Abstract(2544) HTML PDF(16)
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Objective To compare the predictive value of NoSAS score and STOP-Bang questionnaire score, and evaluate the feasibility of NoSAS score screening for OSAHS in physical examination population. Methods Retrospective analysis of the polysomnography (PSG...
Oral Health Status Associated with Quality of Life among the Elderly over 60 Years Old in the Rural Areas of Yunnan Province
Hui DING, Lan YAO
2021, 42(5): 59-63. doi: 10.12259/j.issn.2095-610X.S20210511
Abstract(5341) HTML PDF(21)
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Objective To investigate the oral health status of the elderly over 60 years old in rural areas of Yunnan province, investigate the quality of life of the elderly, and analyze the relationship between the oral health and quality of life. Methods A st...
Investigations on the Poor Vision and Ametropia among Primary School Students in Xundian County of Yunnan Province in 2019
Guang-yong TANG, Lin-guo WANG, Ya-fei MA, Chao-sheng HUANG, Ni PAN, Jing-yao CHEN
2021, 42(5): 64-69. doi: 10.12259/j.issn.2095-610X.S20210512
Abstract(2965) HTML PDF(20)
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Objective To investigate the poor vision and ametropia of primary school students in Xundian County, Yunnan Province in 2019. Methods From November 2018 to November 2019, a total of 3, 764 students in 30 classes from grade one to grade five in six pr...
Clinical Research
Clinical Characteristics of Gastric Cancer in Young Patients: A Retrospective Cohort Study
Yong-ji FU, Fei PENG, Mei GUO, Hua YAN, Qing-cheng SHEN, Jin-xi BAI, Liu YANG
2021, 42(5): 81-86. doi: 10.12259/j.issn.2095-610X.S20210515
Abstract(4280) HTML PDF(14)
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Objective The rate of gastric cancer in young patients has increased over the past few decades. The aim of this study was to analyze the clinical characteristics of young patients with gastric cancer, and investigate the possible risk factors that ma...
Application of “|” Shaped Incision in Concha Plasty
Jing YANG, Zhuo-hui LIU, Rui-qing LONG
2021, 42(5): 92-95. doi: 10.12259/j.issn.2095-610X.S20210517
Abstract(2697) HTML PDF(9)
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Objective To investigate the effect of "|" shaped incision on concha plasty. Methods 68 cases with chronic suppurative otitis media and middle ear cholesteatoma were randomly divided into two groups, with 39 cases in the "|" shaped incision group a...
Changes of the Difference between Hematocrit and Albumin in the Course of Secondary Abdominal Infection
Wang-bin XU, Dong-mei DAI, Mei-e HE, LI Le-yun XIAO, Fei WANG, Lei YANG, Kun TANG
2021, 42(5): 101-106. doi: 10.12259/j.issn.2095-610X.S20210519
Abstract(3132) HTML PDF(10)
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Objective To provide the certain guidance for the accurate treatment of patients with abdominal infection by observing the changes of the difference between HCT and ALB in the treatment of patients with abdominal infection. Methods A total of 106 p...
Clinical Study on Different Doses of Solinaxin Combined with Xingpi Yanger Granule in the Treatment of Primary Nocturnal Enuresis in Children
Ting-ting MAO, Gui-fen LI, Hua-ping CAO, Huang WU
2021, 42(5): 126-130. doi: 10.12259/j.issn.2095-610X.S20210523
Abstract(2685) HTML PDF(7)
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Objective To investigate the effect of different doses of Solina xin combined with Xingpi Yanger granule on primary nocturnal enuresis (PNE) in children. Methods From March 2018 to January 2020, 120 PNE children admitted to Pediatric Internal Medic...
The Analysis of the Efficacy of Ankle Arthroscopic Microfracture in the Treatment of Osteochondral Lesions of the Talus in Different MRI Classifications.
Chuan HE, Yong-de SHU, Teng-yun YANG, Yan-lin LI, Fu-ke WANG, Ren-jie HE, Rui-ying ZHONG, Guang-chao CHEN
2021, 42(5): 70-75. doi: 10.12259/j.issn.2095-610X.S20210513
Abstract(3373) HTML PDF(15)
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Objective To explore the clinical effects of ankle arthroscopic microfracture used in different MRI classifications of osteochondral lesions of the talus. Methods 48 cases with osteochondral lesions of the talus and treated with microfracture under t...
Clinical Evaluation of Simplified Biofunctional Prosthetic Denture in Edentulous Patients
He MENG, Yong-qiang DENG
2021, 42(5): 76-80. doi: 10.12259/j.issn.2095-610X.S20210514
Abstract(3672) HTML PDF(30)
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Objective To evaluate the efficacy and satisfaction of the edentulous patients with the simplified biofunctional prosthetic denture (SBPD). Methods 26 patients with complete denture restoration were randomly divided into two groups: conventional comp...
A Comparative Study of Fecal Bacteria between Patients with Malignant Obstructive Jaundice and Healthy People
Yan-bo SUN, Wei-ming LI, Shu-min LI, Yue-ying LIN, Yun-yun CEN, Peng-yuan XU
2021, 42(5): 87-91. doi: 10.12259/j.issn.2095-610X.S20210516
Abstract(3371) HTML PDF(11)
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Objective To explore the changing characteristics of fecal bacteria in patients with malignant obstructive jaundice. Methods From January 2019 to May 2019, 87 cases with malignant obstructive jaundice were taken as case bank and screened by inclusion...
Abnormal Coagulation Parameters in Patients with Early Colorectal Cancer and Its Clinical Significance
Zi-hong CHEN, Shi-bo SUN, Xian-mei WANG, Shan-shan YU, Xiu-fang WU, Xiang-shan CHEN, Ting GENG, Hong LIU, Xian-min LIU, Qiong NAN
2021, 42(5): 96-100. doi: 10.12259/j.issn.2095-610X.S20210518
Abstract(4170) HTML PDF(13)
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Objective Our aim was to investigate the expression and significance of coagulation markers in patients with early colorectal cancer. Methods This study was conducted by the case-control study to collect data from patients with early colorectal cance...
Effect of Cardiac Exercise Rehabilitation on Cardiac Function and Quality of Life in Patients with Hypertensive Heart Disease Complicated with Heart Failure
Mei CEN, Dan-dan YUAN, Ming JIN, Xue-lian LIU, Wei-wei SHANG
2021, 42(5): 107-113. doi: 10.12259/j.issn.2095-610X.S20210520
Abstract(4125) HTML PDF(22)
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Objective To explore the effect of individualized cardiac rehabilitation exercise program extended in stages on cardiac function and daily living ability in patients with hypertension and heart failure. Methods Sixty patients with heart failure were ...
Correlation Study of Blood Preβ1-HDL Predictive Value of Coronary Artery Disease Severity in Patients with Coronary Heart Disease
Wen-qing MIAO, Yu WANG, Jun YANG, Ni-ni TIAN, Hui-xian DUAN, Xiao-li ZHAO
2021, 42(5): 114-119. doi: 10.12259/j.issn.2095-610X.S20210521
Abstract(3447) HTML PDF(5)
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Objective To investigate the correlation between Pre β1-HDL and the predictive value of coronary artery disease severity in patients with coronary heart disease. Methods In this study, 90 patients undergoing coronary intervention diagnosis and/or tre...
Application of 16SrRNA Gene Detection in the Early Diagnosis of Bacterial Meningitis in Children
Shu-lan SHI, Xi-ting DAI, Guang-zhou ZHAO, Xiao Juan LI, Rong-jie LI, Ming-biao MA
2021, 42(5): 120-125. doi: 10.12259/j.issn.2095-610X.S20210522
Abstract(4252) HTML PDF(9)
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Objective To explore the value of 16SrRNA gene detection in cerebrospinal fluid (CSF) in the early diagnosis of bacterial meningitis (BM) in children. Methods CSF specimens were collected from 40 patients with BM who were diagnosed of BM in Kunming C...
Applications of CT in the Early Prediction of Different Clinical Types of COVID -19 Pneumonia
Yun-hui YANG, Bo HE, Ding-yun YOU, Jun-tao YANG, Qian GAO
2021, 42(5): 131-137. doi: 10.12259/j.issn.2095-610X.S20210524
Abstract(4175) HTML PDF(13)
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Objective To investigate the clinical and CT image characteristics of COVID-19 pneumonia, and the predictive value of CT in the early stage of different clinical types. Methods Chest CT and clinical data of confirmed 143 patients with COVID-19 pneumo...
The Association of Methylenetetrahydrofolate Reductase Gene Polymorphism with Coronary Heart Disease
Liu LI, Xiao-chan ZHANG, Qi RU, Shuo WANG, Quo-qing QI, Hong-liang ZHAO
2021, 42(5): 138-142. doi: 10.12259/j.issn.2095-610X.S20210525
Abstract(2927) HTML PDF(10)
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Objective To analyze the relationship between methylenetetrahydrofolate reductase (MTHFR) gene polymorphism and severity of coronary heart disease. Methods A total of 400 patients who were to undergo coronary angiography and stent implantation when n...
Clinical Significance of Carboxyhemoglobin in Neonatal ABO Hemolytic Jaundice
Wan DENG, Yu-e ZHOU, Tian-yun LIU, Yan-zheng YANG, Li LIN
2021, 42(5): 143-146. doi: 10.12259/j.issn.2095-610X.S20210526
Abstract(3504) HTML PDF(7)
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Objective To investigate the clinical significance of carboxyhemoglobin (COHb) in neonatal ABO hemolytic jaundice. Methods Retrospective analysis was conducted and from January 2019 to December 2019, 68 cases of ABO hemolysis were selected as the obs...
Nursing Forum
Effect of Cluster Nursing on Oral Mucositis and Mouth Opening Limitation in Patients with Nasopharyngeal Carcinoma Undergoing Radiotherapy
Jiang ZHANG, Jiang WU, Xi-juan ZHAO, Yan LIU, Yan SU, Shen-pin YU
2021, 42(5): 170-175. doi: 10.12259/j.issn.2095-610X.S20210531
Abstract(4168) HTML PDF(11)
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Objective To explore the effect of clustered nursing program on oral mucositis and restricted mouth opening in patients with nasopharyngeal carcinoma undergoing radiotherapy. Methods In this study, 119 patients with nasopharyngeal carcinoma admitte...
Effect of Narrative Nursing on Keeping Normal Lactation State of Hospitalized Puerpera after the Separation of Mother and Infant
Wei-hui SHI, Xiao-ping ZHU, Ting-ting ZHANG, Ling WANG, Cong-xiang LIU, Han-qiong DONG
2021, 42(5): 176-180. doi: 10.12259/j.issn.2095-610X.S20210532
Abstract(4105) HTML PDF(23)
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Objective To explore the application effect of narrative nursing in maintaining normal lactation state of parturients with mother infant separation during the hospitalization. Methods Parturients delivered in the Tenth People’ s Hospital Affiliated t...
Reviews
Research Progress of Mesenchymal Stem Cell Exosomes in Oral Tissue Regeneration
Li-ya MA, Nan-quan RAO, He-feng YANG
2021, 42(5): 147-153. doi: 10.12259/j.issn.2095-610X.S20210527
Abstract(4329) HTML PDF(24)
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Cell therapy based on mesenchymal stem cells is one of the important strategies for the tissue regeneration and repair. Recent studies have shown that exosomes, as an important product secreted by mesenchymal stem cells, can play a role similar to pa...
Advances in the Diagnosis and Treatment of Slit Ventricle Syndrome
Xu KANG, Ruo-ping CHEN, Xiao-qiang WANG
2021, 42(5): 154-158. doi: 10.12259/j.issn.2095-610X.S20210528
Abstract(2783) HTML PDF(18)
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Published reports have suggested that patients previously shunted for hydrocephalus or arachnoid cyst may appear slit ventricle syndrome presenting with intermittent headache and narrow ventricles. At present, the pathogenesis and treatment of slit v...
The Pathogenesis of Acromegaly Complicated with Diabetes Mellitus
Jun ZHONG, Jing-yun FU
2021, 42(5): 159-164. doi: 10.12259/j.issn.2095-610X.S20210529
Abstract(4357) HTML PDF(9)
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Hypersecretion of GH in acromegaly produces the insulin resistance and is prone to diabetes mellitus.The main mechanism is that the insulin receptor and its substrate phosphorylation level, phosphatidylinositol 3 kinase regulatory subunit P85 level, ...
The Mechanism of Histones and TLRs in Venous Thrombotic Diseases
Jie WU, Jun LIU, Yan ZHANG, Li REN, Yan-li DANG
2021, 42(5): 165-169. doi: 10.12259/j.issn.2095-610X.S20210530
Abstract(2994) HTML PDF(8)
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In recent years, due to the increase of high-risk pregnancies in obstetrics and the improvement of diagnostic techniques, clinical attention to pregnancy complicated with venous thrombotic diseases is increasing from year to year. Although various ri...