2022 Vol. 43, No. 5

Original Articles Basic of Medicine
Studies on Moisture-absorption-retention and Antioxidant Activity of Panax Notoginseng Polysaccharides in Vitro
Xiaoping WU, Yuling DAI, Ling ZHANG, Hong WANG, Qiong ZOU, Jinji WANG, Yanhong LIU, Tong CHEN
2022, 43(5): 1-6. doi: 10.12259/j.issn.2095-610X.S20220514
Abstract(2361) HTML PDF(140) Cited By (16)
Abstract:
Objective To investigate hygroscopic, moisturizing properties and antioxidant activities in vitro by extracting and separating Panax notoginseng polysaccharides from industrial medicinal residues extracted from Panax notoginseng total saponins. Meth...
Studies on the Preparation Method of Influenza Vaccine Liposome and the Effect of Particle Size on Immunogenicity
Xiaolin LIU, Qingxin XIE, Piao LI, Qian ZHANG, Ai YANG, Weidong LU
2022, 43(5): 7-11. doi: 10.12259/j.issn.2095-610X.S20220508
Abstract(2758) HTML PDF(41) Cited By (2)
Abstract:
Objective (1) To prepare the tetravalent influenza vaccine liposome lyophilized powder with the film dispersion method and freeze-thaw lyophilization method, and to screen the best preparation method by investigating its particle size, entrapment eff...
Luteolin Inhibits HASMCs Migration by Endoplasmic Reticulum Stress
Li ZHANG, Qingcen WANG, Luohui ZHOU, Juan YANG, Hong WANG
2022, 43(5): 12-17. doi: 10.12259/j.issn.2095-610X.S20220518
Abstract(3562) HTML PDF(34) Cited By (3)
Abstract:
Objective To investigate the regulatory effect and mechanism of luteolin on the migration of human aortic smooth muscle cells (HASMCs). Methods HASMCs were cultured in vitro and divided into the blank control group (without any treatment, BC), the ne...
EGCG Improves Myocardial Fibrosis Induced by High Fat and High Sugar Diet in Obese Rats by Inhibiting TGF-β1/Smads Signaling Pathway
Cong LIU, Guishuai WU, Rui PU, Shude LI, Jianping TAO, Renfa ZHANG
2022, 43(5): 18-26. doi: 10.12259/j.issn.2095-610X.S20220506
Abstract(3173) HTML PDF(36) Cited By (3)
Abstract:
Objective To investigate the effects of epigallocatechin gallate (EGCG) on myocardial fibrosis induced by high fat and high sugar diet in obese rats and to explore whether EGCG can reduce the extent of myocardial fibrosis through TGF-β1/Smads signali...
Long Non-coding RNA-p21 Regulates the MicroRNA-9 / Sirtuin-1 Signaling Pathway to Reverse Oxaliplatin Resistance in Colorectal Cancer Cells
Liju ZHANG, Xiaoming JIANG, Changxian CHEN, Xi WU, Zhenyong ZHANG, Weijun LIU
2022, 43(5): 27-32. doi: 10.12259/j.issn.2095-610X.S20220519
Abstract(3414) HTML PDF(33) Cited By (2)
Abstract:
Objectives To discuss the molecular mechanism of long non-coding RNA(lncRNA)-P21 regulating (miR-9) /Sirtuin-1(SIRT1) signaling pathway in reversing colorectal cancer (CRC) cell autophagy and drug resistance. Methods Real-time fluorescent quantitati...
Population Genetic Analysis of 18 Autosomal STR Loci in Minjia Branch of Bai Nationality in Yunnan Province, Southwest China
Wei WEI, Shouxun ZHANG, Chongchong XU, Yanling JIANG, Yi LI, Shuo YANG, Jianli HAN, Kuan LI, Fei ZHAO, Xiaopei YANG, Neng ZHANG, Xiaoxiao LU, Shurong ZHONG
2022, 43(5): 33-43. doi: 10.12259/j.issn.2095-610X.S20220510
Abstract(3133) HTML PDF(35) Cited By (1)
Abstract:
Objective To investigate the genetic polymorphism of 18 autosomal short tandem repeats (STR)loci in 2323 healthy unrelated individuals of Minjia branch of Bai nationality in Yunnan, calculate the population genetic parameters, and establish the genet...
The Genetic Characteristic Analysis of the VP1 Gene of Coxsackievirus A6 in Qujing Prefecture of Yunnan Province in 2020
Sisi CHANG, Lili JIANG, Chunrui LUO, Xiaofang ZHUO, Jianping CUN, Xiaoqing FU, Bingjun TIAN
2022, 43(5): 44-49. doi: 10.12259/j.issn.2095-610X.S20220503
Abstract(2773) HTML PDF(39) Cited By (3)
Abstract:
Objective To analyze the genetic characteristics of the VP1 gene of coxsackievirus A6 (CV-A6) from hand, foot and mouth disease (HFMD) cases collected from Qujing prefecture in 2020. Methods (1) Virus RNA was directly abstracted from stool samples of...
Factors Affecting the Quality of Life in Adolescent Scoliosis
Yunxin ZHAO, Fanyuan MENG, Zhi ZHAO, Luming LI, Lijuan AO, Moxian CHEN
2022, 43(5): 50-57. doi: 10.12259/j.issn.2095-610X.S20220522
Abstract(3676) HTML PDF(44) Cited By (10)
Abstract:
Objective To analyze the differences and their correlations in the scores of pain, self-image, function and mental health of adolescent scoliosis (AS)between the demographic parameters and spinal deformity measurement parameters, and to understand th...
Studies on the Related Factors of Non-suicidal Self-injury in Adolescent Patients with Depression
Li XU, Jinghan ZHAO, Yuxiong JIN, Huizuo FU, Jing YUAN, Xin WANG, Jianzhong YANG
2022, 43(5): 58-64. doi: 10.12259/j.issn.2095-610X.S20220529
Abstract(3838) HTML PDF(59) Cited By (37)
Abstract:
Objective To explore the influencing factors of non-suicidal self-injury (NSSI) in adolescent patients with major depressive disorder. Methods 130 adolescent patients with the first-episode depression in the Psychiatry Department of the Second Affil...
Disease Spectrum Analysis of Elderly Patients in Yunnan Province from 2017 to 2019
Yuan ZHANG, Hong LI, Wenlong CUI, Songyuan TANG, Yingting LIU
2022, 43(5): 65-70. doi: 10.12259/j.issn.2095-610X.S20220520
Abstract(3895) HTML PDF(35) Cited By (4)
Abstract:
Objective To describe and analyze the spectrum of diseases and changes of elderly patients over 60 years old in Yunnan Province. Methods Through the National Health Statistics Information Network Direct Reporting System, the home page of electronic...
Clinical Research
The Effectiveness of Endometrial Receptivity Test for Repeated Implantation Failure and Analysis of Clinical Factors Affecting Implantation Window
Yun BAI, Lei LI, Yuerong WU, Lanping ZHONG
2022, 43(5): 71-75. doi: 10.12259/j.issn.2095-610X.S20220501
Abstract(2983) HTML PDF(32) Cited By (4)
Abstract:
Objective To investigate the efficacy of personalized transplantation of Endometrial Receptivity Test (ERT) in improving the clinical outcome of patients with repeated implantation failure, and to analyze the clinical factors affecting Endometrial Re...
Interrupted Vertical Non-Absorbable Sutures Combined with Nis Knots in the Treatment of Inferior Pole Patella Fractures
Jin JIA, Kaiyu HOU, Zhong CHEN, Xingxi HU, Changyou ZHENG, Junliang JIANG
2022, 43(5): 76-82. doi: 10.12259/j.issn.2095-610X.S20220505
Abstract(2301) HTML PDF(26) Cited By (4)
Abstract:
Objective To Explore the technical points and clinical efficacy of interrupted vertical non-absorbable sutures combined with nis knots in the treatment of inferior patellar pole fractures. Methods A total of 22 patients admitted to the Department of...
Clinical Distribution and Drug Resistance Analysis of Acineto Bacterbaumannii from 2014 to 2020
Jinyi GU, Deyao DENG, Wenli YUAN, Qiuping YANG, Jianmei SONG, Yanjun SHEN, Yuanyuan GUO, Hongyun XU
2022, 43(5): 83-87. doi: 10.12259/j.issn.2095-610X.S20220504
Abstract(3854) HTML PDF(42) Cited By (7)
Abstract:
Objective To observe the clinical distribution and drug-resistance of A.baumannii, so as to provide the reference for the rational use of antibiotics in clinic. Methods Data of 2453 A.baumannii isolated from the clinical samples in a hospital from J...
Effect of Hematopoietic Function Recovery and MRD Status after Induction Chemotherapy on the Prognosis of Patients with Newly Diagnosed Acute Myeloid Leukemia
Ruijuan MA, Feng ZHANG, Ruiting ZHANG, Jin YAO
2022, 43(5): 88-94. doi: 10.12259/j.issn.2095-610X.S20220512
Abstract(3354) HTML PDF(27) Cited By (4)
Abstract:
Objective To investigate the recovery of hematopoietic function after the induction chemotherapy and the effect of MRD status on the prognosis of AML by analyzing retrospectively the clinical data of 100 newly diagnosed AML patients. Methods The clin...
The Analysis of 19 Cases of Odontoma Diagnosed by CBCT Imagining
Hongbin YU, Lingpeng ZHANG, Shibing QIAN, Shulan CUI, Changquan LI, Yuesu HUANG
2022, 43(5): 95-102. doi: 10.12259/j.issn.2095-610X.S20220516
Abstract(4569) HTML PDF(83)
Abstract:
Objective To summarize the imaging characteristics of odontoma based on detailed discussion of the value of CBCT in the diagnosis and treatment of odontoma, thereby improving the clinical understanding of odontoma. Methods A retrospective study was ...
Correlation between CD3+ HLA-DR Expression and Vita Level in Severe Mycoplasma Pneumoniae Pneumonia
Ling HE, Zehao YU
2022, 43(5): 103-107. doi: 10.12259/j.issn.2095-610X.S20220528
Abstract(2940) HTML PDF(21) Cited By (3)
Abstract:
Objective To investigate the expression of CD3 + HLA-DR in peripheral blood lymphocytes and the level of serum VitA in severe Mycoplasma pneumoniae pneumonia. Methods 24 children who met the diagnostic criteria of severe Mycoplasma pneumoniae pneumo...
The Expression and Clinical Significance of Non-coding RNA in Cervical Cancer
Fangyuan GUO, Wenliang LI, Fan XU, Xiangqun WEI
2022, 43(5): 108-116. doi: 10.12259/j.issn.2095-610X.S20220527
Abstract(3090) HTML PDF(15) Cited By (4)
Abstract:
Objective To analyze the expression of long non-coding RNA (LINC00982) and microrNA (hsa-miR-1246) in cervical cancer tissues, so as to provide a new biomarker for the diagnosis of cervical cancer and a potential and effective therapeutic target for ...
Observations on Hemodynamics and Stress Response of the Different Anesthesia Methods in Stereotactic Intracranial Hematoma Removal for Hypertensive Intracerebral Hemorrhage
Guangping ZHAO, Panpan LIU, Fei LIU, Wei LI, Yongxue CHEN, Kai ZHANG
2022, 43(5): 117-122. doi: 10.12259/j.issn.2095-610X.S20220521
Abstract(2922) HTML PDF(12) Cited By (18)
Abstract:
Objective To explore the effect of different anesthesia methods on the hemodynamics and stress response during the stereotactic intracranial hematoma removal of the hypertensive cerebral hemorrhage. Methods 80 patients who underwent the stereotactic...
Expression Characteristics of Inflammatory Factors in the Serum of Patients with Adolescence Polycystic Ovary Syndrome
Xiaowei YUAN, Maohua QIN, Lijun WANG, Tingxian YANG, Jing JIN
2022, 43(5): 123-126. doi: 10.12259/j.issn.2095-610X.S20220517
Abstract(2791) HTML PDF(17) Cited By (6)
Abstract:
Objective To study the expression of CRP, IL-6 and TNF-a in the serum of patients with the suspected adolescence polycystic ovary syndrome (PCOS). Methods 80 patients with the suspected adolescence polycystic ovary syndrome (PCOS)were selected as the...
Effect of Comprehensive Treatment for Aggressive Retinopathy of Prematurity
Siqi WU, Gang CHEN, Yishuang XIAO
2022, 43(5): 127-132. doi: 10.12259/j.issn.2095-610X.S20220513
Abstract(2608) HTML PDF(18) Cited By (2)
Abstract:
Objective To observe the effect of treatment for aggressive posterior retinopathy of prematurity (A-ROP). Methods Retrospective case studies were made and 55 premature infants (110 eyes) who were diagnosed as A-ROP were selected from Kunming Childre...
Diagnostic Value of Gated Myocardial Perfusion Imaging Combined with NT-proBNP in Chronic Heart Failure
Feipeng WU, Xiandong ZHENG, Qiyan WU, Liju HONG, Lei YUE, Rui YANG, Dandan CHEN, Youjun ZHOU
2022, 43(5): 133-139. doi: 10.12259/j.issn.2095-610X.S20220511
Abstract(3500) HTML PDF(12) Cited By (5)
Abstract:
Objectives To investigate the clinical value of gated myocardial perfusion imaging (GMPI), high-sensitivity C-reactive protein (Hs-CRP) and N-terminal B-type natriuretic peptide (NT-proBNP) in the differential diagnosis of chronic heart failure. Me...
Measurement of Articular Cartilage Thickness of Talus in Normal Adults by MRI
Chaoyu BAO, Sixue PAN, Guangxiong HE, Jiliang XIA, Shuai CHEN, Junyi XIANG
2022, 43(5): 140-143. doi: 10.12259/j.issn.2095-610X.S20220502
Abstract(3056) HTML PDF(27) Cited By (2)
Abstract:
Objective To measure the thickness of cartilage on the surface of the talus of normal adults by MRI and to obtain the parameters of the thickness of the cartilage of the talus of normal adults and the relationship with gender, age, weight and height....
Predictive Value of RDW and Blood Lipid on Gastroesophageal Variceal Bleeding in Patients with Liver Cirrhosis
Qingqing WANG, Jie DING, Hongjie YANG, Guoji CHANG, Siqi LIU, Lijuan HUA, Yiying WANG, Shenghao LI
2022, 43(5): 144-148. doi: 10.12259/j.issn.2095-610X.S20220509
Abstract(3097) HTML PDF(21) Cited By (5)
Abstract:
Objective To explore the correlation between the red blood cell distribution width (RDW) / lipids and gastroesophageal variceal bleeding (GEVB) in patients with liver cirrhosis. Methods A total of 60 GEVB patients admitted to the Comprehensive Hepat...
Predictive Model of Risk Factors for the Recurrence of Liver Cirrhosis with Pleural Effusion
Min ZHOU, Zhihui MA, Jiayan LI, Jianhua FAN, Ling LIN, Tingying YU, Huifang ZHANG, Li LIU
2022, 43(5): 149-154. doi: 10.12259/j.issn.2095-610X.S20220524
Abstract(4247) HTML PDF(17)
Abstract:
Objective To explore the independent risk factors of the recurrence of pleural effusion in patients with liver cirrhosis and complicated with pleural effusion and to establish a predictive model. Methods 190 cases of liver cirrhosis complicated wit...
Reviews
Research Progress of Heroin-induced Respiratory Damage
Yong ZHOU, Zunyue ZHANG, Jiqing YANG, Pu XIONG, Kunhua WANG
2022, 43(5): 155-161. doi: 10.12259/j.issn.2095-610X.S20220525
Abstract(2577) HTML PDF(21) Cited By (1)
Abstract:
Heroin, a highly addictive drug that seriously harms the human health, can be ingested in multiple ways. Severe damages are commonly observed in the respiratory system. As an exogenous opioid, heroin can cause the respiratory depression by inhibiting...
Research Progress in the Risk Factors and Prevention Strategies of Thyroid Cancer
Huajie WU, Nan ZHANG, Lei LI, Han QIAO, Guoping LI
2022, 43(5): 162-167. doi: 10.12259/j.issn.2095-610X.S20220526
Abstract(4592) HTML PDF(149) Cited By (31)
Abstract:

Thyroid cancer is the most common malignant tumor in endocrine system. Its morbidity is increasing worldwide year by year. The exact cause of thyroid cancer is still unclear. Radiation exposure, metabolic syndrome (such as obesity, hypertention, hype...

Teaching Research
The Application of “Modular Teaching Method” in the Nursing Teaching of Nephrology Department
Jiping ZHOU, Junling ZHANG, Qing LIU, Xingmei LI, Peiyou FAN, Heling JIANG
2022, 43(5): 168-172. doi: 10.12259/j.issn.2095-610X.S20220523
Abstract(3107) HTML PDF(27) Cited By (9)
Abstract:
Objective To explore the application effect of “modular teaching method” in the nursing teaching of the Nephrology Department, and to provide the reference for the clinical teaching. Methods 192 undergraduate nursing students practicing in the Depar...
Nursing Forum
Correlation between the Acceptance of Illness and Quality of Life in Patients with Inflammatory Bowel Disease
Rong LIU, Yang SUN, Fameng LUO, Dezhi TAO, Haiyan ZHANG
2022, 43(5): 173-178. doi: 10.12259/j.issn.2095-610X.S20220507
Abstract(5031) HTML PDF(21) Cited By (9)
Abstract:
Objective To investigate the status of disease acceptance and the quality of life in patients with the inflammatory bowel disease (IBD), and to explore the relationship between them. Methods A total of 345 patients with IBD attending the Inflammator...
Construction and Application of the Health Literacy Assessment Scale for Day Surgery Patients and Its Influence on Early Postoperative Recovery Quality
Chuntao WU, Ke LIN
2022, 43(5): 179-184. doi: 10.12259/j.issn.2095-610X.S20220515
Abstract(3373) HTML PDF(30) Cited By (2)
Abstract:
Objective To investigate the health literacy level of day surgery patients by developing and constructing a health literacy assessment tool, and to analyze the impact of health literacy level of day surgery patients on early postoperative rehabilitat...