2021 Vol. 42, No. 8

Original Articles Basic of Medicine
Hypoglycemic Effects of Swertia Punicea Hemsl on Alloxan-Induced Diabetic Mice
Shao-long KANG, Hui-ling WANG, Dong-mei LI, Yong LAI, Huai XIAO
2021, 42(8): 11-16. doi: 10.12259/j.issn.2095-610X.S20210803
Abstract(3160) HTML PDF(23) Cited By (3)
Abstract:
Objective To screen the hypoglycemic activity of 4 extracts of Swertia Punicea Hemsl. Methods The ethanol extract of Swertia Punicea Hemsl was extracted by ethanol extraction, and the extracts were successively extracted with petroleum ether, chlor...
Therapeutic Effect of GW7647 on Non-alcoholic Fatty Liver Disease in Rats
Yong-fang XU, Na WU, Yue-xin HU, Yong-mei ZHAO, Shao-ding ZHENG, Ling WEI, Si-jia ZHENG, Jian-jun LIU
2021, 42(8): 17-22. doi: 10.12259/j.issn.2095-610X.S20210804
Abstract(3705) HTML PDF(42)
Abstract:
Objective To establish a rat model of nonalcoholic fatty liver disease (NAFLD) and to explore the therapeutic effect of peroxidase activator receptor (PPAR) agonist GW7647 on rat NAFLD. Methods After the experimental animals were grouped, GW7647 wa...
Effects and Mechanism of Anlotinib on Radiosensitivity of Non-small Cell Lung Cancer Cell Lines A549
Hong-min DUAN, Nan CHEN, Yong-yan YANG, Yun-xia LI, Jin-xiang FENG, Hang LI, Xiu-wen HUANG, Dong-jin LV, Ming ZHANG, Yu-tao ZHAO
2021, 42(8): 40-46. doi: 10.12259/j.issn.2095-610X.S20210808
Abstract(4009) HTML PDF(31) Cited By (7)
Abstract:
Objective To investigate the effect and mechanism of anlotinib on radiosensitization of human lung adenocarcinoma cell line A549. Methods Human lung adenocarcinom cell line A549 was treated with anlotinib and/or radiotherapy, then divided in to fou...
Analysis of Hypertension and Its Influencing Factors in Dai and Jingpo Ethnic Groups in Dehong
Feng-ting MU, Chang-hong MU, Li-ping HE, Xiao-mei LI, Wen-jia ZHANG, Zhen YU, Qing-huan YANG, Hong-qin KE
2021, 42(8): 54-59. doi: 10.12259/j.issn.2095-610X.S20210810
Abstract(4282) HTML PDF(26) Cited By (3)
Abstract:
Objective To explore the current status of hypertension in Dai and Jingpo groups in Dehong Prefecture, and to analyze the influencing factors of hypertension, provide informed intervention and treatment, and control the prevalence. Methods A total o...
Transplantation of Nurr1 Gene-modified Embryo Midbrain Neural Stem Cells for Treatment in Parkinson’ s Disease
Yi-sheng QIAO, Xiao-xiang CHEN, Jiao-tian XU, Wei WANG, Chao ZHANG, Xiao-bin SONG, Zhi-yong YANG, Xing-li DENG
2021, 42(8): 1-6. doi: 10.12259/j.issn.2095-610X.S20210801
Abstract(4345) HTML PDF(42) Cited By (4)
Abstract:
Objective To investigate the therapeutic effect of transplanted Nurr1 gene-modified embryo midbrain neural stem cells in Parkinson’ s rats. Methods 1. Establishment of Parkinson’ s disease animal model in SD rats. 2. Primary culture of embryo midbrai...
Determination of Volatile Components of Blaps rhynchoptera by Headspace Solid Phase Microextraction-Gas Chromatography-Mass Spectrometry
Jie-li SU, Bi-tao LI, Yun-song WANG, Rong-sheng LI, Xing-ping ZHANG, Long-hui BAI, Kou WANG, Zheng-qi WEN
2021, 42(8): 7-10. doi: 10.12259/j.issn.2095-610X.S20210802
Abstract(2393) HTML PDF(26) Cited By (3)
Abstract:
Objective To determine the volatile components of the dried Blaps rhynchoptera Fairmaire. Methods Headspace solid phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS) were used to analysis and identify the volati...
Effect of PTEN Gene Expression on Apoptosis of Thyroid Cancer Cells BCPAP and FTC133 and Expression of ERK and AKT
Jian-wei SUN, Qian XIANG, Zi-chao LIU, Shan-shan XU, Ding DING
2021, 42(8): 23-30. doi: 10.12259/j.issn.2095-610X.S20210805
Abstract(4883) HTML PDF(28) Cited By (4)
Abstract:
Objective To investigate the effect of PTEN gene expression on the apoptosis of BCPAP cells and FTC133 thyroid cancer cells and on the expression of signal pathway proteins ERK and AKT. Methods BCPAP cells and FTC133 cells were transfected with PTEN-...
Isolation and Identification of Chemical Constituents of Ethyl Acetate Extraction Layer from Buddleja Officinalis Maxim
Fang LIU, Yun-ping GUO, Bo LIU, Chang-qi CHEN, Ya-ni GUO
2021, 42(8): 31-34. doi: 10.12259/j.issn.2095-610X.S20210806
Abstract(3634) HTML PDF(29)
Abstract:
Objective To extract and identify the chemical constituents from ethyl acetate layer of the Buddleja officinalis Maxim. Methods The chemical constituents were isolated by silica gel column chromatography, Spehadex LH-20、HPLC and other methods, and MS...
Determination of Norfloxacin Glucose Injection in EDTA by RP-HPLC Method
Na-na RONG, YU-feng LI, Li-yue REN, Yue-xin HU
2021, 42(8): 35-39. doi: 10.12259/j.issn.2095-610X.S20210807
Abstract(2845) HTML PDF(32) Cited By (5)
Abstract:
Objective To establish a method for determination of norfloxacin glucose injection in compound EDTA injection. Methods The chromatographic column was Shiseido C18-MGⅡ5 μm 4.6×250 mm, with the mobile phase of acetonitrile: 0.05 mol/L ammonium acetate:...
Endogenous NO Mediated Stargazin Nitroso Modification in Synaptic Plasticity after Cerebral Ischemia Reperfusion
Shu-hua FANG, Xin-sheng CHEN, Li CAO, Na WANG
2021, 42(8): 47-53. doi: 10.12259/j.issn.2095-610X.S20210809
Abstract(3085) HTML PDF(26) Cited By (6)
Abstract:
Objective To investigate the role of Stargazin-nitroso modification in synaptic plasticity after cerebral ischemia and reperfusion, and to investigate the molecular mechanism of NO regulating AMPAR “trafficking”. Methods The rat model of focal cerebr...
Satisfaction Status of Public Health Service Capacity in Poor Mountainous Area of Western Yunnan
Guo-qing ZHANG, Jia ZHOU, Rui YAN, Bing ZHANG, Lin-rong LI, Li LI, Ying PAN
2021, 42(8): 60-64. doi: 10.12259/j.issn.2095-610X.S20210811
Abstract(3518) HTML PDF(29) Cited By (1)
Abstract:
Objective To investigate the recognition and satisfaction of medical institutions on public health service in the poor mountainous areas of western Yunnan, to explore issues and solutions, and to provide countermeasures and suggestions for the capaci...
Clinical Research
Correlation Between Serum Soluble ST2 and Cardiac Remodeling in Patients with Heart Failure with Reduced Ejection Fraction
Wei-wen WANG, De-xia LI, Jie ZHANG, Lin LI
2021, 42(8): 71-77. doi: 10.12259/j.issn.2095-610X.S20210813
Abstract(3744) HTML PDF(26) Cited By (5)
Abstract:
Objective To investigate the correlation between serum soluble oncogenic inhibitor 2 (sST2) level and cardiac function and remodeling in patients with heart failure (HFrEF) with reduced ejection fraction. Methods A total of 110 patients with HFrEF ...
The Application Value of Dry Fluorescent Luminescence in The Diagnosis and Treatment of HBV Infection
Song-qin LV, Xi-ruo SUN, Shan HUANG, Li-ping XV, Juan ZHANG, Yi-na WANG, Xiao-fei LI, Yong-rui YANG
2021, 42(8): 65-70. doi: 10.12259/j.issn.2095-610X.S20210812
Abstract(3442) HTML PDF(21) Cited By (1)
Abstract:
Objective To analyze and evaluate the application value of dry fluorescent luminescence in the diagnosis and treatment of HBV infection. Methods A total of 397 serum samples were collected from patients attending Liver Diseases Department of the Thir...
The Detection Rate of Musculoskeletal Ultrasound in Patients with Rheumatic Knee Arthritis and Its Correlation with Knee Function
Xin WU, Yun LI, Pin-fei ZOU, Mei-ling LI, Yong-bin PU
2021, 42(8): 78-82. doi: 10.12259/j.issn.2095-610X.S20210814
Abstract(4190) HTML PDF(14) Cited By (13)
Abstract:
Objective To investigate the detection rate of musculoskeletal ultrasonography in patients with rheumatic knee arthritis and its correlation with knee function. Methods A total of 118 patients with rheumatic knee arthritis (all patients with one knee...
Correlation Between Hepatitis C Virus Infection and Type 2 Diabetes Mellitus
Li-xuan YAO, Ben NIU, Wei YUE, Wen-lin ZHOU, Ya-ting ZHANG
2021, 42(8): 83-89. doi: 10.12259/j.issn.2095-610X.S20210815
Abstract(4651) HTML PDF(19) Cited By (1)
Abstract:
Objective To investigate the prevalence of and risk factors for type 2 diabetes mellitus in patients with chronic viral hepatitis C. Methods A total of 294 patients with chronic hepatitis C in Yunnan First People’ s Hospital from January 2018 to May ...
Effect of Tracheotomy Timing in Patients with Severe Cerebrovascular Disease
Peng-peng SUN, Zhi-jing LIU, Meng ZHANG, Jing-dong WANG, Sheng ZHANG, Lai-zang WANG, Peng BAI
2021, 42(8): 90-94. doi: 10.12259/j.issn.2095-610X.S20210816
Abstract(3275) HTML PDF(20) Cited By (3)
Abstract:
Objective To evaluate the effect of tracheotomy at different time in patient with severe cerebrovascular disease. Methods A retrospective analysis was conducted on 56 patients with severe cerebrovascular disease who underwent tracheotomy in Qingdao C...
Drug Resistance of Escherichia coli and Klebsiella pneumoniae in Children with Bloodstream Infection from 2017 to 2020
Hai-lin HUANG, Hong-chao JIANG, Xiao-juan LI
2021, 42(8): 95-100. doi: 10.12259/j.issn.2095-610X.S20210817
Abstract(5067) HTML PDF(18) Cited By (11)
Abstract:
Objective To analyze the drug resistance of Escherichia coli and Klebsiella pneumoniae causing bloodstream infection in our hospital from 2017 to 2020, so as to provide reference for clinical treatment of children with bloodstream infection. Methods ...
Expression and Significance of microRNA-21 and EGFR in Non-small Cell Lung Cancer
Ying-xia WANG, Qin HE, Guo-fang WANG, Xuan ZHANG
2021, 42(8): 101-105. doi: 10.12259/j.issn.2095-610X.S20210818
Abstract(4214) HTML PDF(27) Cited By (5)
Abstract:
Objective To explore the expression and significance of microRNA-21 and its regulatory gene EGFR in non-small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma. Methods Lung tissue samples of 30 patients with pathologically confirmed ...
Clinical Characteristics of Newly Diagnosed Type 2 Diabetes Mellitus and Influencing Factors of Glycosylated Hemoglobin Among Tibetans in Deqin
Qiong ZHOU, Bao-kun PENG, Xiao-chun WENG, Zhen JU, Nuo-pi-chu SUN, Zhe TANG
2021, 42(8): 106-110. doi: 10.12259/j.issn.2095-610X.S20210819
Abstract(4903) HTML PDF(16) Cited By (2)
Abstract:
Objective To investigate the clinical characteristics of newly diagnosed type 2 diabetes mellitus (T2DM) patients among Tibetans in Deqin, analyze the influencing factors of HbA1c, and explore the correlation between HbA1c and hemoglobin (Hb) in Tibe...
The Correlation between Epicardial Adipose Tissue and Coronary Artery Atherosclerosis with the Dual-source CT
Wen-bin ZHANG, Dan HAN, Yang TIAN, Wei ZHAO
2021, 42(8): 111-117. doi: 10.12259/j.issn.2095-610X.S20210820
Abstract(3368) HTML PDF(16) Cited By (3)
Abstract:
Objective To explore the correlation between adipose tissue around the heart (pericardial adipose tissue, PAT; epicardial adipose tissue, EAT) and severity of coronary artery atherosclerosis with the Dual-source CT. Methods 223 patients suspected wit...
Analysis of Vaginal Microecological in Women with Cervical Intraepithelial Neoplasia and Cervical Cancer
Ding-ji TAN, Hong-li YIN, Rui ZHU, Xi ZHANG, Xin YU, Yong FEI, Xin LI, Ming DUAN, Liang HE, Hong-ying YANG
2021, 42(8): 118-122. doi: 10.12259/j.issn.2095-610X.S20210821
Abstract(5228) HTML PDF(28) Cited By (14)
Abstract:
Objective To investigate the characteristics of vaginal microecology in patients with cervical intraepithelial neoplasia and cervical cancer, and provide information for the prevention and treatment of cervical diseases. Methods From July 2018 to Oct...
The Value of Endocervical Curettage in Cervical Cancer Screening
Juan ZHANG, Hong-yun ZHANG
2021, 42(8): 123-127. doi: 10.12259/j.issn.2095-610X.S20210822
Abstract(4137) HTML PDF(22) Cited By (11)
Abstract:
Objective To investigate the value of colposcopic cervix tube scraping (ECC) in the detection of low grade squamous intraepithelial lesions (LSIL) and above. Methods The clinical data of 1104 women who underwent cervical thin-thickness liquid-based c...
Tiger17 Promotes the Proliferation and Migration of Human Oral Mucosa Fibroblast Cells
Shun-hui YIN, Jian-zhong ZHOU, Zi-liang LI
2021, 42(8): 128-131. doi: 10.12259/j.issn.2095-610X.S20210823
Abstract(4305) HTML PDF(34)
Abstract:
Objective To investigate the effects of different concentrations of Tiger17 on the proliferation and migration of human oral mucosa fibroblast cells (hOMF) for different periods of time. Methods The cells were cultured and migration of hOMF cells tre...
The Correlation between Vitamin D Receptor Gene Bg1I and Cdx-2 Polymorphism and Hashimoto’ s Thyroiditis
Xiao-hui RUAN, Qian XIANG, Yu-ming WANG, Zhi-han ZHOU, Xian ZHANG, Yan GUO, Xiao-rui YANG
2021, 42(8): 132-139. doi: 10.12259/j.issn.2095-610X.S20210824
Abstract(4565) HTML PDF(24) Cited By (6)
Abstract:
Objective To investigate the correlation between Vitamin D receptor gene Bg1I, Cdx-2 polymorphism with Hashimoto’ s thyroiditis (HT). Methods The SNP of VDR gene Bg1I and CDX-2 in 178 HT patients were detected by TaqMan fluorescent probe, including 5...
Condyle Position and Symmetry in Transverse Discrepancy Patients with Temporomandibular Joint Disorders
Rui WANG, Juan-juan JI, Zhi ZHOU, Shuang YANG, Ya-ling ZHU
2021, 42(8): 140-147. doi: 10.12259/j.issn.2095-610X.S20210825
Abstract(2765) HTML PDF(24) Cited By (1)
Abstract:
Objective To investigate condylar morphology, position and mandibular symmetry in transverse discrepancy patients with temporomandibular joint disorders compared to those with normal occlusion. Methods 18 transverse discrepancy patients with temporom...
Clinical Efficacy of Standardized Exercise Prescription Rehabilitation Training on Lumbar Intervertebral Disc Herniation
Ying GAO, Mei-qi WAMG
2021, 42(8): 148-151. doi: 10.12259/j.issn.2095-610X.S20210826
Abstract(2745) HTML PDF(23) Cited By (20)
Abstract:
Objective To explore the clinical efficacy of standardized exercise prescription on pain, immobility, depression and other related symptoms in patients with herniated lumbar disc. Methods 40 patients with lumbar intervertebral disc herniation were en...
AIDS Research
Disease Distribution Pattern Among HIV/AIDS Inpatients in Kunming from 2012 to 2020
Bo TIAN, Jun LIU, Li-hua ZHANG, Rong HE, Shan-qun GU, Chong-xi LI
2021, 42(8): 152-157. doi: 10.12259/j.issn.2095-610X.S20210827
Abstract(3849) HTML PDF(23) Cited By (6)
Abstract:
Objective To investigate the incidence and trends of opportunistic infections in hospitalized patients with HIV/AIDS in Kunming. Methods The data of 7756 inpatients were retrospective analyzed in the third people’ s hospital of Kunming from 2012 to 2...
Reviews
Advances on Complement Factor H and Cardiovascular Disease
Cheng-zhen ZHU, Xing ZHANG, Hao GUO
2021, 42(8): 158-163. doi: 10.12259/j.issn.2095-610X.S20210828
Abstract(3423) HTML PDF(61) Cited By (3)
Abstract:
Cardiovascular diseases is a serious threat to human health, which is characterized by high morbidity, high lethality and disability. In recent years, studies have found that complement factor H (CFH) is a very important negative regulator in the com...
Teaching Research
Effect of "Flipped Classroom" Teaching Mode Based on Mobile Platform Applied to Nursing Students in Blood Purification Center
Tian ZHANG, Yu-hui ZHOU, Li FAN, Li-fen GUO, Feng SONG
2021, 42(8): 164-169. doi: 10.12259/j.issn.2095-610X.S20210829
Abstract(2982) HTML PDF(15) Cited By (5)
Abstract:
Objective To explore the effect of mobile platform-based "flipped classroom" teaching mode on nursing students’ performance, autonomous learning ability and academic self-efficacy. Methods (1) Intern nursing students in the Blood Purification Center ...
Nursing Forum
Effect of Moist Exposed Burn Ointment on Retention Time of Positive Pressure Venous Needle in Neurosurgery Department
Yan-bei CHEN, Ping YAO, Hua-tao NIU
2021, 42(8): 170-173. doi: 10.12259/j.issn.2095-610X.S20210830
Abstract(2612) HTML PDF(13) Cited By (2)
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Objective To investigate the effect of Moist Exposed Burn Ointment on the retaining time of positive-pressure intravenous indwelling needle in patients with infusion of special medications. Methods A total of 200 patients in our department who receiv...
Effect of Family-centered Care on Quality of Life in Patients Underwent Heart Valve Replacement
Xiao-lu YANG, Shu-juan WANG, Xiang-feng BAI
2021, 42(8): 174-176. doi: 10.12259/j.issn.2095-610X.S20210831
Abstract(3733) HTML PDF(17) Cited By (7)
Abstract:
objective To explore the post-operative quality of life in cardiac valve replacement patients. Method A total of 200 patients who had undergone the first mechanical heart valve replacement within 1 year (July 2018 to July 2019) in the Department of C...
Shared Decision-making in Patients with Primary Liver Cancer During Perioperative Period
Ying ZHANG, Jing GUO, Tao FENG, Yan ZHOU, Yao HUANG, Xiao-feng DENG, LU ZHENG
2021, 42(8): 177-180. doi: 10.12259/j.issn.2095-610X.S20210832
Abstract(4624) HTML PDF(17) Cited By (19)
Abstract:
Objective To investigate the effect of the shared decision-making in patients with primary liver cancer during perioperative period. Methods A total of 120 patients with primary liver cancer who underwent laparoscopic hepatectomy from November 1, 202...