2021 Vol. 42, No. 8
2021, 42(8): 11-16.
doi: 10.12259/j.issn.2095-610X.S20210803
Abstract:
Objective To screen the hypoglycemic activity of 4 extracts of Swertia Punicea Hemsl. Methods The ethanol extract of Swertia Punicea Hemsl was extracted by ethanol extraction, and the extracts were successively extracted with petroleum ether, chlor...
2021, 42(8): 17-22.
doi: 10.12259/j.issn.2095-610X.S20210804
Abstract:
Objective To establish a rat model of nonalcoholic fatty liver disease (NAFLD) and to explore the therapeutic effect of peroxidase activator receptor (PPAR) agonist GW7647 on rat NAFLD. Methods After the experimental animals were grouped, GW7647 wa...
Effects and Mechanism of Anlotinib on Radiosensitivity of Non-small Cell Lung Cancer Cell Lines A549
2021, 42(8): 40-46.
doi: 10.12259/j.issn.2095-610X.S20210808
Abstract:
Objective To investigate the effect and mechanism of anlotinib on radiosensitization of human lung adenocarcinoma cell line A549. Methods Human lung adenocarcinom cell line A549 was treated with anlotinib and/or radiotherapy, then divided in to fou...
2021, 42(8): 54-59.
doi: 10.12259/j.issn.2095-610X.S20210810
Abstract:
Objective To explore the current status of hypertension in Dai and Jingpo groups in Dehong Prefecture, and to analyze the influencing factors of hypertension, provide informed intervention and treatment, and control the prevalence. Methods A total o...
2021, 42(8): 1-6.
doi: 10.12259/j.issn.2095-610X.S20210801
Abstract:
Objective To investigate the therapeutic effect of transplanted Nurr1 gene-modified embryo midbrain neural stem cells in Parkinson’ s rats. Methods 1. Establishment of Parkinson’ s disease animal model in SD rats. 2. Primary culture of embryo midbrai...
2021, 42(8): 7-10.
doi: 10.12259/j.issn.2095-610X.S20210802
Abstract:
Objective To determine the volatile components of the dried Blaps rhynchoptera Fairmaire. Methods Headspace solid phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS) were used to analysis and identify the volati...
2021, 42(8): 23-30.
doi: 10.12259/j.issn.2095-610X.S20210805
Abstract:
Objective To investigate the effect of PTEN gene expression on the apoptosis of BCPAP cells and FTC133 thyroid cancer cells and on the expression of signal pathway proteins ERK and AKT. Methods BCPAP cells and FTC133 cells were transfected with PTEN-...
2021, 42(8): 31-34.
doi: 10.12259/j.issn.2095-610X.S20210806
Abstract:
Objective To extract and identify the chemical constituents from ethyl acetate layer of the Buddleja officinalis Maxim. Methods The chemical constituents were isolated by silica gel column chromatography, Spehadex LH-20、HPLC and other methods, and MS...
2021, 42(8): 35-39.
doi: 10.12259/j.issn.2095-610X.S20210807
Abstract:
Objective To establish a method for determination of norfloxacin glucose injection in compound EDTA injection. Methods The chromatographic column was Shiseido C18-MGⅡ5 μm 4.6×250 mm, with the mobile phase of acetonitrile: 0.05 mol/L ammonium acetate:...
2021, 42(8): 47-53.
doi: 10.12259/j.issn.2095-610X.S20210809
Abstract:
Objective To investigate the role of Stargazin-nitroso modification in synaptic plasticity after cerebral ischemia and reperfusion, and to investigate the molecular mechanism of NO regulating AMPAR “trafficking”. Methods The rat model of focal cerebr...
2021, 42(8): 60-64.
doi: 10.12259/j.issn.2095-610X.S20210811
Abstract:
Objective To investigate the recognition and satisfaction of medical institutions on public health service in the poor mountainous areas of western Yunnan, to explore issues and solutions, and to provide countermeasures and suggestions for the capaci...
2021, 42(8): 71-77.
doi: 10.12259/j.issn.2095-610X.S20210813
Abstract:
Objective To investigate the correlation between serum soluble oncogenic inhibitor 2 (sST2) level and cardiac function and remodeling in patients with heart failure (HFrEF) with reduced ejection fraction. Methods A total of 110 patients with HFrEF ...
2021, 42(8): 65-70.
doi: 10.12259/j.issn.2095-610X.S20210812
Abstract:
Objective To analyze and evaluate the application value of dry fluorescent luminescence in the diagnosis and treatment of HBV infection. Methods A total of 397 serum samples were collected from patients attending Liver Diseases Department of the Thir...
2021, 42(8): 78-82.
doi: 10.12259/j.issn.2095-610X.S20210814
Abstract:
Objective To investigate the detection rate of musculoskeletal ultrasonography in patients with rheumatic knee arthritis and its correlation with knee function. Methods A total of 118 patients with rheumatic knee arthritis (all patients with one knee...
2021, 42(8): 83-89.
doi: 10.12259/j.issn.2095-610X.S20210815
Abstract:
Objective To investigate the prevalence of and risk factors for type 2 diabetes mellitus in patients with chronic viral hepatitis C. Methods A total of 294 patients with chronic hepatitis C in Yunnan First People’ s Hospital from January 2018 to May ...
2021, 42(8): 90-94.
doi: 10.12259/j.issn.2095-610X.S20210816
Abstract:
Objective To evaluate the effect of tracheotomy at different time in patient with severe cerebrovascular disease. Methods A retrospective analysis was conducted on 56 patients with severe cerebrovascular disease who underwent tracheotomy in Qingdao C...
2021, 42(8): 95-100.
doi: 10.12259/j.issn.2095-610X.S20210817
Abstract:
Objective To analyze the drug resistance of Escherichia coli and Klebsiella pneumoniae causing bloodstream infection in our hospital from 2017 to 2020, so as to provide reference for clinical treatment of children with bloodstream infection. Methods ...
2021, 42(8): 101-105.
doi: 10.12259/j.issn.2095-610X.S20210818
Abstract:
Objective To explore the expression and significance of microRNA-21 and its regulatory gene EGFR in non-small cell lung cancer, lung adenocarcinoma and squamous cell carcinoma. Methods Lung tissue samples of 30 patients with pathologically confirmed ...
2021, 42(8): 106-110.
doi: 10.12259/j.issn.2095-610X.S20210819
Abstract:
Objective To investigate the clinical characteristics of newly diagnosed type 2 diabetes mellitus (T2DM) patients among Tibetans in Deqin, analyze the influencing factors of HbA1c, and explore the correlation between HbA1c and hemoglobin (Hb) in Tibe...
2021, 42(8): 111-117.
doi: 10.12259/j.issn.2095-610X.S20210820
Abstract:
Objective To explore the correlation between adipose tissue around the heart (pericardial adipose tissue, PAT; epicardial adipose tissue, EAT) and severity of coronary artery atherosclerosis with the Dual-source CT. Methods 223 patients suspected wit...
2021, 42(8): 118-122.
doi: 10.12259/j.issn.2095-610X.S20210821
Abstract:
Objective To investigate the characteristics of vaginal microecology in patients with cervical intraepithelial neoplasia and cervical cancer, and provide information for the prevention and treatment of cervical diseases. Methods From July 2018 to Oct...
2021, 42(8): 123-127.
doi: 10.12259/j.issn.2095-610X.S20210822
Abstract:
Objective To investigate the value of colposcopic cervix tube scraping (ECC) in the detection of low grade squamous intraepithelial lesions (LSIL) and above. Methods The clinical data of 1104 women who underwent cervical thin-thickness liquid-based c...
2021, 42(8): 128-131.
doi: 10.12259/j.issn.2095-610X.S20210823
Abstract:
Objective To investigate the effects of different concentrations of Tiger17 on the proliferation and migration of human oral mucosa fibroblast cells (hOMF) for different periods of time. Methods The cells were cultured and migration of hOMF cells tre...
2021, 42(8): 132-139.
doi: 10.12259/j.issn.2095-610X.S20210824
Abstract:
Objective To investigate the correlation between Vitamin D receptor gene Bg1I, Cdx-2 polymorphism with Hashimoto’ s thyroiditis (HT). Methods The SNP of VDR gene Bg1I and CDX-2 in 178 HT patients were detected by TaqMan fluorescent probe, including 5...
2021, 42(8): 140-147.
doi: 10.12259/j.issn.2095-610X.S20210825
Abstract:
Objective To investigate condylar morphology, position and mandibular symmetry in transverse discrepancy patients with temporomandibular joint disorders compared to those with normal occlusion. Methods 18 transverse discrepancy patients with temporom...
2021, 42(8): 148-151.
doi: 10.12259/j.issn.2095-610X.S20210826
Abstract:
Objective To explore the clinical efficacy of standardized exercise prescription on pain, immobility, depression and other related symptoms in patients with herniated lumbar disc. Methods 40 patients with lumbar intervertebral disc herniation were en...
2021, 42(8): 152-157.
doi: 10.12259/j.issn.2095-610X.S20210827
Abstract:
Objective To investigate the incidence and trends of opportunistic infections in hospitalized patients with HIV/AIDS in Kunming. Methods The data of 7756 inpatients were retrospective analyzed in the third people’ s hospital of Kunming from 2012 to 2...
2021, 42(8): 158-163.
doi: 10.12259/j.issn.2095-610X.S20210828
Abstract:
Cardiovascular diseases is a serious threat to human health, which is characterized by high morbidity, high lethality and disability. In recent years, studies have found that complement factor H (CFH) is a very important negative regulator in the com...
Cardiovascular diseases is a serious threat to human health, which is characterized by high morbidity, high lethality and disability. In recent years, studies have found that complement factor H (CFH) is a very important negative regulator in the com...
2021, 42(8): 164-169.
doi: 10.12259/j.issn.2095-610X.S20210829
Abstract:
Objective To explore the effect of mobile platform-based "flipped classroom" teaching mode on nursing students’ performance, autonomous learning ability and academic self-efficacy. Methods (1) Intern nursing students in the Blood Purification Center ...
2021, 42(8): 170-173.
doi: 10.12259/j.issn.2095-610X.S20210830
Abstract:
Objective To investigate the effect of Moist Exposed Burn Ointment on the retaining time of positive-pressure intravenous indwelling needle in patients with infusion of special medications. Methods A total of 200 patients in our department who receiv...
2021, 42(8): 174-176.
doi: 10.12259/j.issn.2095-610X.S20210831
Abstract:
objective To explore the post-operative quality of life in cardiac valve replacement patients. Method A total of 200 patients who had undergone the first mechanical heart valve replacement within 1 year (July 2018 to July 2019) in the Department of C...
2021, 42(8): 177-180.
doi: 10.12259/j.issn.2095-610X.S20210832
Abstract:
Objective To investigate the effect of the shared decision-making in patients with primary liver cancer during perioperative period. Methods A total of 120 patients with primary liver cancer who underwent laparoscopic hepatectomy from November 1, 202...