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RSS2021 Vol. 42, No. 6
2021, 42(6): 29-37.
doi: 10.12259/j.issn.2095-610X.S20210632
Abstract:
Objective To investigate the protective effect of metformin on the kidney in type II diabetes mellitus （T2DM） by regulating the activity of poly （ADP-ribose） polymerase 1 （PARP-1） and investigate the mechanism of this effect. Methods Wistar rats we...
2021, 42(6): 50-55.
doi: 10.12259/j.issn.2095-610X.S20210625
Abstract:
Objective To investigate the protective effect and mechanism of ginsenoside Rg1 on the kidneys of type 2 diabetic rats. Methods A high-sugar and high-fat diet + low-dose streptozotocin （STZ） was used to establish a type 2 diabetic rat model. Ginsen...
2021, 42(6): 56-61.
doi: 10.12259/j.issn.2095-610X.S20210608
Abstract:
Objective To investigate the flavone constituents from Baeckeafrutescens and evaluate the cytotoxic effects of these isolates. Methods The chemical compositions were isolated by normal- and reverse-phase silica gel column chromatography, MCI gel co...
2021, 42(6): 1-6.
doi: 10.12259/j.issn.2095-610X.S20210647
Abstract:
Objective To investigate the effects of pure and multiple cerebral concussion （MCC） on the changes of anxiety behaviors in rats. Methods There were 50 adult SD rats with single pendulum closed brain injury device to simulate pure concussion （PCC） and...
2021, 42(6): 7-15.
doi: 10.12259/j.issn.2095-610X.S20210639
Abstract:
Objective To observe the therapeutic of PNS on wound healing and the expression of PDGF-BB, PDGFR-β in rats superficial second-degree burn model, and to explore the underlying mechanism of PNS on second-degree burn wound healing. Methods Rats with su...
2021, 42(6): 16-21.
doi: 10.12259/j.issn.2095-610X.S20210633
Abstract:
Objective To study the effect of norathyriol on uric acid excretion indicators in hyperuricemic nephropathy （HN） rats induced by adenine and potassium oxazinate. Method Sixty male SD rats were randomly divided into normal group, model group, norathyr...
2021, 42(6): 22-28.
doi: 10.12259/j.issn.2095-610X.S20210642
Abstract:
Objective To investigate the natural active compound Usenamine [C18H17NO6, 6-acetyl-2-（1-amino-ethylene）-7, 9-dihydroxy-8, 9b-dimethyl-9bH- diphenylfuran -1, 3-dione] is safe to use. Methods SPF mice were selected for oral toxicity test, in vivo and ...
2021, 42(6): 38-44.
doi: 10.12259/j.issn.2095-610X.S20210606
Abstract:
Objective To investigate the interaction among RANTES gene promoter region rs2280788 C/G polymorphism, CCR5 gene promoter region rs1799987 G/A polymorphism and environmental factors in the development of Type 2 diabetes mellitus （T2DM） in the Han eth...
2021, 42(6): 45-49.
doi: 10.12259/j.issn.2095-610X.S20210645
Abstract:
Objective To observe the neuronal activation and structural changes after the stimulation of the nucleus accumbens （NAc） in mice by detecting c-Fos protein and structural plasticity, and to preliminally explore the mechanism of neural regulation by u...
2021, 42(6): 62-66.
doi: 10.12259/j.issn.2095-610X.S20210624
Abstract:
Objective To study the dental caries and periodontal status, and to investigate the factors that affect the dental caries of the undergraduate students. Methods A sample of undergraduate students was selected using a multi-stage sampling method. Four...
2021, 42(6): 76-81.
doi: 10.12259/j.issn.2095-610X.S20210603
Abstract:
Objective To analyze the effects of homocysteine （Hcy） on blood pressure, blood glucose and blood lipid in a longitudinal cohort study, so as to provide basis knowledge for the prevention and treatment of related chronic diseases. Methods 987 physi...
2021, 42(6): 82-87.
doi: 10.12259/j.issn.2095-610X.S20210607
Abstract:
Objective To determine the effect of the Neuregulin-1 and its receptor ErbB4（NRG1-ErbB4） polymorphisms on focal epilepsy. Methods Three single nucleotide polymorphisms （SNPs） of NRG1 gene and three single nucleotide polymorphisms （SNPs） of ErbB4 ge...
2021, 42(6): 88-93.
doi: 10.12259/j.issn.2095-610X.S20210644
Abstract:
Objective To provide scientific basis for improving the treatment efficiency of chest pain center for patients with acute myocardial infarction, comparing and analyzing the epidemiological characteristics of hospitalized patients with acute myocardia...
2021, 42(6): 103-109.
doi: 10.12259/j.issn.2095-610X.S20210618
Abstract:
Objective To evaluate the causes and influencing factors of re-hospitalization of patients with coronary heart disease by coronary angiography, so as to guide clinical diagnosis and treatment decisions and reduce re-hospitalization. Methods From Ja...
2021, 42(6): 67-71.
doi: 10.12259/j.issn.2095-610X.S20210615
Abstract:
Objective To investigate the efficacy of 0.01% atropine eye drops combined with visual function training in patients with mild myopia and its influence on visual acuity. Methods A total of 86 patients with mild myopia treated in Yuxi People’ s Hospit...
2021, 42(6): 72-75.
doi: 10.12259/j.issn.2095-610X.S20210617
Abstract:
Objective To evaluate the association between neutrophil-lymphocyte ratio （NLR） and renal damage in patients with systemic lupus erythematosus （SLE）. Methods A total of 410 patients with SLE from the Department of Rheumatology and Immunology of the F...
2021, 42(6): 94-97.
doi: 10.12259/j.issn.2095-610X.S20210637
Abstract:
Objective To study the pharmacokinetics of etomidate in patients with varying degrees of burns. Methods 45 burn patients who underwent escharetomy and skin grafting, and they were divided into A.B.C three groups according to light, mooderate and seve...
2021, 42(6): 98-102.
doi: 10.12259/j.issn.2095-610X.S20210626
Abstract:
Objective To observe the effect of Kan Fu Xin combined with Montmorillonite on the prevention and treatment of radiation-induced oral mucositis in patients with Head and Neck Cancer. Methods In this trial, we included 138 patients with head and neck ...
2021, 42(6): 110-114.
doi: 10.12259/j.issn.2095-610X.S20210614
Abstract:
Objective To provide reference for clinical rational use of vancomycin through analyzing the monitoring results of vancomycin plasma concentration in patients with intracranial infection or/and pulmonary infection after neurosurgery in our hospital. ...
2021, 42(6): 115-118.
doi: 10.12259/j.issn.2095-610X.S20210629
Abstract:
Objective To investigate the characteristics of root canal system of mandibular first and second molars ina Kunming population with cone-beam computed tomography technology. Methods CBCT dada of 1229 mandibular first and second molar from 358 patient...
2021, 42(6): 119-123.
doi: 10.12259/j.issn.2095-610X.S20210631
Abstract:
Objective To detect the serum levels of the inflammatory factors TNF-α and IL-6 in patients with chronic thromboembolic pulmonary hypertension （CTEPH） and further study their clinical significance in CTEPH. Methods A retrospective analysis was perfor...
2021, 42(6): 124-128.
doi: 10.12259/j.issn.2095-610X.S20210643
Abstract:
Objective The correlation between pulmonary artery diameter measured by high resolution computedtomography （HRCT） and pulmonary artery pressure measured by echocardiography in patients with chronic obstructive pulmonary disease （COPD） was investigate...
2021, 42(6): 129-133.
doi: 10.12259/j.issn.2095-610X.S20210611
Abstract:
Objective To observe the influence of mirror therapy combined with occupational therapy on upper limb motor function and ADL in hemiplegia after stroke. Methods Totally 72 patients with hemiplegia after stroke were randomly assigned to the mirror the...
2021, 42(6): 134-138.
doi: 10.12259/j.issn.2095-610X.S20210616
Abstract:
Objective To observe the effect of MHI （Manual Hyperinflation） on diaphragmatic movement and pulmonary function in stroke patients. Methods 67 stroke patients were randomly divided into treatment group （n = 35） and control group （n = 32）. The treatme...
2021, 42(6): 139-145.
doi: 10.12259/j.issn.2095-610X.S20210622
Abstract:
Objective To analyze the safety of cefoperazone Sodium and Sulbactam Sodiumfor injection in Kunming medical institutions, explore the influencing factors of adverse reactions （ADR） and the correlation between the factors, so as to construct the predi...
2021, 42(6): 152-155.
doi: 10.12259/j.issn.2095-610X.S20210601
Abstract:
Periodontitis is a common chronic infectious disease. It is one of the main causes of tooth loss in adults and seriously affects the quality of life of patients. With the development of laser technology, laser therapies are gradually used in various ...
Periodontitis is a common chronic infectious disease. It is one of the main causes of tooth loss in adults and seriously affects the quality of life of patients. With the development of laser technology, laser therapies are gradually used in various ...
2021, 42(6): 146-151.
doi: 10.12259/j.issn.2095-610X.S20210630
Abstract:
Laser is generally used in in all kinds of oral treatment, for its convenience, safety and comfort. Researches of Neodymium-doped yttrium aluminum garnet laser as well as erbium-doped yttrium aluminum garnet laser in the scientific and clinical resea...
Laser is generally used in in all kinds of oral treatment, for its convenience, safety and comfort. Researches of Neodymium-doped yttrium aluminum garnet laser as well as erbium-doped yttrium aluminum garnet laser in the scientific and clinical resea...
2021, 42(6): 156-160.
doi: 10.12259/j.issn.2095-610X.S20210613
Abstract:
Objective To explore the application of PBL teaching based on microlecture as a carrier in standardized training of residents. Methods Forty-five trainees of standardized training of clinical residents in 2019 were taken as the research objects and r...
2021, 42(6): 161-165.
doi: 10.12259/j.issn.2095-610X.S20210605
Abstract:
Objective To improve the quality of life of patients, we use systematic intervention with standardized management model to intervene ankylosing spondylitis （AS） to improve the disease awareness and living quality. Methods This study selected 100 pati...
2021, 42(6): 166-169.
doi: 10.12259/j.issn.2095-610X.S20210646
Abstract:
Objective To investigate the effect of intermittent prone position ventilation in neonatal respiratory distress syndrome （NRDS） in rats. Methods 120 cases of NRDS children undergoing mechanical ventilation from January 2020 to December 2020 in the pe...
2021, 42(6): 170-174.
doi: 10.12259/j.issn.2095-610X.S20210636
Abstract:
Objective To explore the application effect of integrated intervention with multiple follow-up methods on high-risk discharged patients with venous thromboembolism. Methods A total of 192 patients in the Second Department of General Surgery of Yan’ a...
