2024 Vol. 45, No. 9

Expert Forum
Research Progress of siRNA Targeting Against HSV-1
Lei ZHOU, Wenwen LYU, Yongzhong DUAN, Wen QIAN, Jishuai CHENG
2024, 45(9): 1-8. doi: 10.12259/j.issn.2095-610X.S20240901
Abstract(800) HTML PDF(60)
Abstract:
HSV-1 is an important pathogen that can be carried and transmitted in various populations and can cause diseases including herpes labialis, capsulatus, keratitis and viral encephalitis. Although there are several types of HSV-1 vaccines in various st...
Original Articles Basic of Medicine
Effect of HPV E6 on Proliferation,Invasion and Migration of Cervical Cancer Cells Through Rap1 Signaling Pathway
Xiangchuan QIN, Jinqiu LI, Xiaojing HUANG, Kuerban HUTUBIDING·, Hasim AXIANGU·
2024, 45(9): 9-16. doi: 10.12259/j.issn.2095-610X.S20240902
Abstract(466) HTML PDF(22)
Abstract:
Objective To investigate the effect of human papillomavirus E6 protein (HPV E6) on the proliferation, invasion and migration of Hela cells of cervical cancer and its potential molecular mechanism. Methods Illumina Hiseq 4000 transcriptome sequencing...
Effect of Inhibiting PPARγ Expression on Osteogenic Differentiation of BMSCs
Long PU, Xuanran ZHOU, Chenrong JIANG, Yunxuan LI, Yong YUAN
2024, 45(9): 17-23. doi: 10.12259/j.issn.2095-610X.S20240903
Abstract(1278) HTML PDF(20)
Abstract:
Objective To investigate the impact of inhibiting peroxisome proliferator-activated receptor γ (PPARγ) expression on osteogenic differentiation of BMSCs, so as to provide a theoretical basis for the treatment of primary osteoporosis (POP). Methods B...
Analysis of Dietary Nutrition Literacy among Ethnic Minorities in Yunnan Province
Yuan RUAN, Juanjuan LI, Yanling YANG, Qingqing WAN, Jiang ZHAO, Qiang ZHANG, Zhitao LIU
2024, 45(9): 24-29. doi: 10.12259/j.issn.2095-610X.S20240904
Abstract(1009) HTML PDF(13)
Abstract:
Objective To analyze the nutrition knowledge and attitudes and factors associated with dietary nutrition literacy of Ji Nuo, Jing Po, De Ang, A Chang, Bu Lang and Pu Mi ethnic minorities in Yunnan Province from January 2018 to August 2020. Methods T...
Clinical Research
Analysis of Genetic Diagnosis Results for Thalassemia in Childbearing Age Population in Baoshan City
Peng LI, Qionghua GENG, Qingsu FAN, Xuemei LI, Jie ZHANG, Zili ZHANG, Caiwei WU, Yuzhen HU
2024, 45(9): 30-34. doi: 10.12259/j.issn.2095-610X.S20240905
Abstract(1445) HTML PDF(12)
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Objective To investigate the gene-carrying rate of thalassemia in the population of Baoshan. Methods A total of 874 samples were α-thalassemia and β-thalassemia detected by NGS, and the ethnic characteristics of the population were statistically anal...
Construction of a Nomogram Model of Tsutsugamushi Disease Complicated with Sepsis Based on Lasso Regression
Xing LIU, Weixian LI, Xiang ZHU, Mengxing LIU, Na LI, Jiawei XIA, Le ZHANG, Yan WU, Shenghao LI
2024, 45(9): 35-41. doi: 10.12259/j.issn.2095-610X.S20240906
Abstract(484) HTML PDF(19)
Abstract:
Objective To establish a nomogram model for tsutsugamushi disease complicated with sepsis based on Lasso regression, so as to provide a reference for the diagnosis and treatment of tsutsugamushi disease complicated with sepsis. Methods We selected p...
Prevalence of Hypertension and Its Relationship with Clustering of Risk Factors of Cardiovascular Diseases in The Elderly of Han Majority and Ha Ni Ethnic Minority in Rural District of Mojiang County of Yunnan Province
You HUANG, Guohui LI, Duli LIU, Zizi YU, Mei ZUO, Qin LI, Bo LYU, Le CAI
2024, 45(9): 42-48. doi: 10.12259/j.issn.2095-610X.S20240907
Abstract(541) HTML PDF(7)
Abstract:
Objective To analyze the prevalence of hypertension and its relationship with the clustering of risk factors of cardiovascular diseases(CVD) in the elderly of Han majority and Ha Ni ethnic minority in rural districts of Yunnan Province. Methods The ...
Correlation between 24-hour Urinary Sodium Excretion,IL-18 Level and Urinary Albumin in Patients with Type 2 Diabetes Mellitus
Longqiao TAN, Li SHI, Jianfang LIU, Xuemei XIA, Li ZHU, Yushan XU
2024, 45(9): 49-55. doi: 10.12259/j.issn.2095-610X.S20240908
Abstract(387) HTML PDF(18)
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Objective To evaluate the effects of different sodium intake levels and serum inflammatory factors on the risk of urinary albumin (UA) in patients with type 2 diabetes mellitus (T2DM) by using 24 h UNa as an indicator of sodium intake. Methods 130 T...
Analysis of Laboratory Index Characteristics in Newly Treated Smear-Negative Pulmonary Tuberculosis Patients
Xinye YANG, Nian ZHANG, Sha MA, Linpei HUANG, Xueyi LI, Xiaoping HUANG, Mi ZHANG, Cuixian YANG, Xicheng WANG
2024, 45(9): 56-61. doi: 10.12259/j.issn.2095-610X.S20240909
Abstract(640) HTML PDF(14)
Abstract:
Objective To explore the differences in laboratory test index characteristics among smear-negative pulmonary tuberculosis patients, smear-positive pulmonary tuberculosis patients and healthy people. Methods Fifty patients with initial treatment of p...
Analysis of Clinical and Radiological Outcomes between UBE Procedure and Conventional Open Surgery in the Treatment of Lumbar Disc Herniation
Heng DING, Le HU, You LI, Liang CUI, Fan ZHANG, Xingguo LI
2024, 45(9): 62-69. doi: 10.12259/j.issn.2095-610X.S20240910
Abstract(1712) HTML PDF(40) Cited By (1)
Abstract:
Objective To compare the clinical efficacy and imaging results of unilateral biportal endoscopic discectomy (UBE) with traditional open surgery for the treatment of lumbar disc herniation. Methods We retrospectively analyzed 84 patients with single-...
Application of Logistic Regression and Decision Tree Model in Prediction of Adverse Reactions of Iodinated Contrast Medium
Wenxiu XU, Xiaofeng MO, Xiangmin YANG, Silu YANG, Fan WU, Te LI
2024, 45(9): 70-75. doi: 10.12259/j.issn.2095-610X.S20240911
Abstract(1533) HTML PDF(20) Cited By (1)
Abstract:
Objective Logistic regression and decision tree model were used to analyze the influencing factors of adverse reactions of iodine contrast agents. Methods The adverse reaction group consisted of 129 patients who underwent CT examination using ICM an...
Research on Socioeconomic Impact of Self-management in Patients with Chronic Heart Failure
Rong SU, Ling LIN, Ailing YANG, Mingguo ZHANG, Yunfei LI, Yasha LIANG
2024, 45(9): 76-82. doi: 10.12259/j.issn.2095-610X.S20240912
Abstract(697) HTML PDF(18)
Abstract:
Objective To investigate the socioeconomic impact of self-management in patients with chronic heart failure(CHF) . Methods Convenient sampling method was used to investigated and analyzed the self-management of 1762 CHF patients aged 18~89 one month...
Prevalence and Influence Factors of Renal Function Impairment in Patients Following Radical Cystectomy:A Systematic Review and Meta-analysis
Qingmei YU, Tao SHI, Hongxue GUAN, Yujun MAO, Zhaoyi LI, Jiao YANG
2024, 45(9): 83-90. doi: 10.12259/j.issn.2095-610X.S20240913
Abstract(770) HTML PDF(9)
Abstract:
Objective To systematically evaluate the incidence and influencing factors of postoperative renal dysfunction in patients undergoing radical cystectomy. Methods The cohort studies and case-control studies related to postoperative renal function dama...
The Risk and Influencing Factors of Vascular Dementia in Middle-aged and Elderly People in Kunming
Shumei QIU, Jingrui YANG, Xuecai QIU
2024, 45(9): 91-96. doi: 10.12259/j.issn.2095-610X.S20240914
Abstract(674) HTML PDF(7)
Abstract:
Objective To explore the factors influencing the onset of vascular dementia (VD), a nomogram model was constructed, incorporating both serological and clinical indicators. Methods In the Physical Examination Department of the First Affiliated Hospit...
A Preliminary Survey of Physicians' Knowledge of Gout Diagnosis and Treatments in Anning City,Yunnan Province
Xixi ZHOU, Changyong KANG, Yannan YANG, Caihong GAO, Linan ZHAO, Fang FANG
2024, 45(9): 97-102. doi: 10.12259/j.issn.2095-610X.S20240915
Abstract(308) HTML PDF(16)
Abstract:
Objective To investigate the knowledge and awareness of physicians in Anning City regarding the diagnosis and treatment of gout, and explore the influencing factors. Methods From January to April 2024, a questionnaire survey was conducted among gene...
Analysis of Risk Factors Related to Female Infertility and Countermeasures
Yingjie YAO, Maohua QIN, Yunyan CHEN, Rongfang HUANG, Yunjie YANG, Nana LU, Haiqing WANG
2024, 45(9): 103-109. doi: 10.12259/j.issn.2095-610X.S20240916
Abstract(856) HTML PDF(15) Cited By (1)
Abstract:
Objective To investigate the etiology and influencing factors of female infertility. Methods A total of 776 infertile women who visited Kunming Maternal and Child Health Hospital from July 2021 to June 2023 were collected. Multiple Logistic regressi...
Effect of PCV-VG Mode Combined with Dexmedetomidine on Intraoperative Respiratory Mechanics and Blood Gas Indicators in Patients Undergoing Laparoscopic Sleeve Gastrectomy
Hongmei BAO, Rong QIN, Yu ZHANG, Meiju YANG, Gang SU
2024, 45(9): 110-115. doi: 10.12259/j.issn.2095-610X.S20240917
Abstract(234) HTML PDF(5)
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Objective To explore the effects of PCV-VG ventilation mode combined with dexmedetomidine sedation on intraoperative respiratory mechanics and blood gas indicators in obese patients undergoing laparoscopic sleeve gastrectomy. Methods 132 patients wh...
Observation of Achieving Controlled Low Central Venous Pressure with Goal-directed Fluid Therapy Combined with Milrinone in Laparoscopic Hepatic Lobectomy
Bo PENG, Gang SU, Rong QIN, Rong WEN, Wei YIN
2024, 45(9): 116-121. doi: 10.12259/j.issn.2095-610X.S20240918
Abstract(642) HTML PDF(6)
Abstract:
Objective To investigate the effect of goal-directed fluid therapy combined with milrinone in achieving controlled low central venous pressure (CLCVP) in laparoscopic hepatic lobectomy. Methods Sixty patients undergoing laparoscopic hepatectomy at t...
Analysis of Relevant Indicators for Acute Traumatic Head Injury Upon Immediate Admission
Xiaogai NIE, Yunfang ZHANG, Shanshan ZHUANG, Kun TU, Jiao WANG
2024, 45(9): 122-128. doi: 10.12259/j.issn.2095-610X.S20240919
Abstract(1089) HTML PDF(13) Cited By (1)
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Objective To explore the test indicators closely related to the incidence and prognosis of acute traumatic head injury. Methods The data of 156 patients with head injuries admitted to the emergency department from October 2022 to June 2023 after the...
Meta-analysis of the Impact of Early Enteral Nutrition on the Clinical Outcomes of Very Low Birth Weight Premature Infants
Shuang FANG, Libo ZHU, Ling LIU, Yanhua XU, Xue HU
2024, 45(9): 129-135. doi: 10.12259/j.issn.2095-610X.S20240920
Abstract(346) HTML PDF(4)
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Objective To evaluate the effect of early enteral nutrition on the clinical outcomes of very low birth weight preterm infants. Methods The literature on the use of early enteral nutrition and clinical outcome measures in VLBW premature infants was s...
Investigation on the Factors Influencing Emotional Perception and General Mental Health of Medical Students
Zhengmin YANG, Xuejuan HUANG, Xuemeng LIANG, Hao SUN, Xin PENG, Wei CHANG
2024, 45(9): 136-143. doi: 10.12259/j.issn.2095-610X.S20240921
Abstract(882) HTML PDF(8)
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Objective To understand the emotional perception and general mental health status of medical students, and explore related influencing factors to promote mental health education for medical students. Methods An on-site questionnaire survey was condu...
Clinical Analysis of Two Methods in the Treatment of Cholecystolithiasis Combined with Choledocholithiasis
Zhitang GUO, Kui LONG, Zhangbin CHEN, Weiran LIAO, Jiayun GE, Wei ZHANG
2024, 45(9): 144-150. doi: 10.12259/j.issn.2095-610X.S20240922
Abstract(514) HTML PDF(9)
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Objective To compare the clinical therapeutic effects of Laparoscopic cholecystectomy (LC) + laparoscopic common bile duct exploration and primary suture (LBEPS) and LC + laparoscopic common bile duct exploration through cystic duct (LTCBDE). Method...
Clinical Study of Vacuum Sealing Drainage Combined with Growth Factor in Treatment of Diabetic Foot Ulcer
Yan LYU, Yanbin WANG, Zhiguo REN, Qingxin JIANG, Ran WEI, Jiting ZHENG, Changqing FAN
2024, 45(9): 151-155. doi: 10.12259/j.issn.2095-610X.S20240923
Abstract(519) HTML PDF(13)
Abstract:
Objective To investigate the clinical effect of vacuum sealing drainage (VSD) combined with human epidermal growth factor in the treatment of diabetic foot ulcers. Methods A total of 62 patients diagnosed with diabetic foot ulcer (wagner grade 2~4) ...
AIDS Research
Social Support Status and Influencing Factors of HIV-infected Patients on Antiviral Therapy
Xuelin XIANG, Hongrui ZHAO, Zhongjie WANG, Yu XIA, Min MA, Huadan WANG, Liping. HE
2024, 45(9): 156-162. doi: 10.12259/j.issn.2095-610X.S20240924
Abstract(762) HTML PDF(6) Cited By (1)
Abstract:
Objective To understand the status quo of social support of HIV patients in Yunnan Province and explore its influencing factors, so as to provide a reference for improving the social support status of this population in the future. Methods Multi-sta...
Effect Observation and Influencing Factors Analysis of Rapid Initiation of Antiretroviral Therapy
Bo TIAN, Jun LIU, Chongxi LI, Wei ZHANG, Meiqin FANG, Haiyun CHEN, Jingping BAI, Xin ZHOU, Lei CHENG, Yongmei JIN
2024, 45(9): 163-167. doi: 10.12259/j.issn.2095-610X.S20240925
Abstract(992) HTML PDF(8)
Abstract:
Objective To investigate the efficacy of 48 weeks of rapid initiation of HIV antiviral therapy in Kunming, and analyze the influencing factors of Non-rapid initiation. Methods Data of patients initially receiving HIV antiviral treatment in The Third...
Reviews
Research Progress on Osteogenic Differentiation of Apical Papilla Stem Cells
Shibing QIAN, Huiping SHI, Yanqiu LI, Rongyu YANG, Kaiwen DUAN
2024, 45(9): 168-173. doi: 10.12259/j.issn.2095-610X.S20240926
Abstract(768) HTML PDF(19)
Abstract:
Stem cells from apical papilla (SCAP) have a strong multi-line differentiation potential, in which osteogenic differentiation can be applied to bone tissue regeneration, providing a new idea for the treatment of oral jaw defects. Osteogenic different...
Teaching Research
Application of Flipped Classroom Mixed Teaching Mode in Standardized Training of Radiology Residents
Xinyan ZHOU, Na TAN, Xirui DUAN, Xiaolan DU, Guochen LI, Guifang SUN, Rui ZHAO, Chengde LIAO, Tengfei KE
2024, 45(9): 174-179. doi: 10.12259/j.issn.2095-610X.S20240927
Abstract(965) HTML PDF(18) Cited By (1)
Abstract:
Objective To evaluate the application effect of the blended flipped classroom teaching mode on the academic performance, critical thinking ability, and teaching satisfaction of radiology residents. Methods Sixty radiology residents trained in our de...
Nursing Forum
Disinfecting Effect of Three Disinfectants on the Ultrasonic Scaling Unit Waterline
Yang LYU, Guiding LI, Shaowen LU, Binbing YU, Qiuju ZHAI, Yi PENG
2024, 45(9): 180-188. doi: 10.12259/j.issn.2095-610X.S20240928
Abstract(388) HTML PDF(18)
Abstract:
Objective To assess the efficacy of three disinfectants in disinfecting the ultrasonic scaling unit waterline. Methods Twelve periodontal ultrasonic scalers were randomly divided into four groups based on the disinfection protocol: distilled water (...