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RSS2022 Vol. 43, No. 8
2022, 43(8): 1-6.
doi: 10.12259/j.issn.2095-610X.S20220801
Abstract:
Objective To explore serum uric acid （SUA） lowering effect of polyethylene glycol 4000 （PEG4000） on male Kunming-DY rats （uricase-deficient rats）. Methods A total of 24 45-day male Kunming-DY rats were selected and divided into control group （n = 6）...
2022, 43(8): 7-16.
doi: 10.12259/j.issn.2095-610X.S20220802
Abstract:
Objective To investigate regulatory effect of the Lentivirus-mediated-GATA-3 RNAi （si-GATA-3）on the Th1/Th2 imbalance in a murine model of allergic rhinitis in vitro. Methods The lentiviral vector SI-GATA-3 with GATA-3 gene mediated by RNAi was dev...
2022, 43(8): 17-27.
doi: 10.12259/j.issn.2095-610X.S20220804
Abstract:
Objective To analyze the potential molecular biological mechanism of scutellarin for the treatment of atherosclerosis （AS） based on network pharmacology. Methods The PubChem database was used to predict the potential targets of scutellarin, and the ...
2022, 43(8): 28-33.
doi: 10.12259/j.issn.2095-610X.S20220803
Abstract:
Objective To analyze the characteristics of katG and inhA genetic mutations associated with INH-resistant Mycobacterium tuberculosis in Yunnan Province. Methods The INH-resistant Mycobacterium tuberculosis isolates were collected from drug-resistant...
2022, 43(8): 34-40.
doi: 10.12259/j.issn.2095-610X.S20220806
Abstract:
Objective To explore the specific effect of LL-37 on the destruction of the transmembrane barrier function of bladder urothelial cells and develop a cellular experimental model suitable for studying interstitial cystitis （IC） in vitro. Methods Human...
2022, 43(8): 41-46.
doi: 10.12259/j.issn.2095-610X.S20220805
Abstract:
Objective To investigate the protective effect of interleukin-4 （IL-4） on acute lung injury （ALI）. Methods ALI cell models were developed using lipopolysaccharide （LPS） to induce A549 cells. The model was treated with different concentrations of IL-...
2022, 43(8): 47-55.
doi: 10.12259/j.issn.2095-610X.S20220807
Abstract:
Objective To compare the differences in serum Val and Met concentrations in healthy people, patients with benign breast tumors and breast cancer patients, and explore the relationship between serum valine and methionine and the clinical characteristi...
2022, 43(8): 56-60.
doi: 10.12259/j.issn.2095-610X.S20220808
Abstract:
Objective To explore the clinical characteristics of melanoma in our hospital, and provide a reference for the prevention and treatment of melanoma. Methods The clinical data of melanoma patients diagnosed in the Third Affiliated Hospital of Kunming...
2022, 43(8): 61-65.
doi: 10.12259/j.issn.2095-610X.S20220809
Abstract:
Objective To investigate the efficacy of blood transfusion combined with radiotherapy and chemotherapy in patients with colorectal cancer and its effects on tumor markers and T lymphocyte levels. Methods A retrospective analysis was performed on 68 ...
2022, 43(8): 66-71.
doi: 10.12259/j.issn.2095-610X.S20220810
Abstract:
Objective To investigate the influence of butylphthalide on National Institute of Health stroke Scale （NIHSS） and hemorheology in patients with acute cerebral infarction. Methods A total of 66 patients with acute cerebral infarction admitted to the...
2022, 43(8): 72-80.
doi: 10.12259/j.issn.2095-610X.S20220814
Abstract:
Objective To analyze the clinical manifestations of scrub typhus in children , and the risk factors that may progress to critical cases were discussed, so as to provide a basis for clinicians to diagnose and identify critical patients as soon as poss...
2022, 43(8): 81-86.
doi: 10.12259/j.issn.2095-610X.S20220811
Abstract:
Objective To study the epidemiological characteristics of patients triaged in the emergency department during COVID-19 pandemic in our hospital in 2020 to provide a reference basis for further optimizing the diagnosis and treatment services, response...
2022, 43(8): 87-92.
doi: 10.12259/j.issn.2095-610X.S20220812
Abstract:
Objective To explore the health literacy management and related influencing factors of type-Ⅱ diabetes mellitus patients and thus provide a basis for improving the health literacy management of diabetic inpatients in community hospitals in Kunming. ...
2022, 43(8): 93-99.
doi: 10.12259/j.issn.2095-610X.S20220813
Abstract:
Objective To explore the effect of integrating palliative care to reduce the pain and anxiety symptoms of liver cancer patients. Methods 60 patients with hepatitis related liver cancer in Kunming Third People’s Hospital were divided into standard t...
2022, 43(8): 100-105.
doi: 10.12259/j.issn.2095-610X.S20220815
Abstract:
Objective To study the influencing factors of poor prognosis before and after revascularization of acute ischemic stroke, so as to provide more biomarkers for prognosis prediction. Methods A total of 179 patients with acute ischemic stroke who recei...
2022, 43(8): 106-112.
doi: 10.12259/j.issn.2095-610X.S20220816
Abstract:
Objective To construct a predictive model of AAT and cytokines in the diagnosis of active pulmonary tuberculosis. Methods A total of 96 patients with active pulmonary tuberculosis admitted to the Third People’s Hospital of Kunming from March 2020 t...
2022, 43(8): 113-121.
doi: 10.12259/j.issn.2095-610X.S20220817
Abstract:
Objective To investigate the application value of Silva typing pattern in prognosis of HPV-associated endocervicalnadenocarcinoma （HPVA）. Methods A total of 95 cases of invasive HPVA diagnosed by pathology department in the Third Affiliated Hospital...
2022, 43(8): 122-126.
doi: 10.12259/j.issn.2095-610X.S20220821
Abstract:
Objective To investigate the characteristics and significance of immune function in patients with active and non-active pulmonary tuberculosis. Methods A total of 78 patients with active tuberculosis treated in Kunming Third People’s Hospital from ...
2022, 43(8): 127-131.
doi: 10.12259/j.issn.2095-610X.S20220820
Abstract:
Objective To investigate the clinical characteristics of varicella-zoster virus （VZV） infection in immunocompromised population. Methods From January 2020 to December 2021 in the Third People’s Hospital of Kunming, 38 cases of VZV infection in immu...
2022, 43(8): 132-137.
doi: 10.12259/j.issn.2095-610X.S20220822
Abstract:
Objective To explore the value and application of electroencephalogram, short latency somatosensory evoked potential and transcranial Doppler ultrasound in the determination of brain death. Methods 31 patients with brain death in our hospital were e...
2022, 43(8): 138-144.
doi: 10.12259/j.issn.2095-610X.S20220823
Abstract:
Objective To investigate the changes in serum PCT, IL-6, SAA levels and clinical characteristics of pediatric rotavirus （RV） and norovirus （NV） enteritis, and to analyze the factors for distinguishing the two. Methods In a prospective observational...
2022, 43(8): 145-149.
doi: 10.12259/j.issn.2095-610X.S20220824
Abstract:
Objective To analyze the distribution, epidemiological characteristics, clinical symptoms and high-risk factors of pertussis in Yunnan Province, and to explore the epidemiology, clinical characteristics and high-risk factors of pertussis. Methods Da...
2022, 43(8): 150-155.
doi: 10.12259/j.issn.2095-610X.S20220825
Abstract:
Objective To understand the recent infection status and influencing factors of HIV-1 infected men who have sex with men （MSM） newly reported by non-governmental organizations （NGO） in Kunming city from January 2018 to December 2020, and to provide gu...
2022, 43(8): 156-160.
doi: 10.12259/j.issn.2095-610X.S20220831
Abstract:
COVID-19 virus is the pathogen of the new type of corona virus disease 2019, a global infectious disease that began to spread at the end of 2019. It has caused damage to multiple organs particularly human respiratory tract. Oral lesions is considered...
COVID-19 virus is the pathogen of the new type of corona virus disease 2019, a global infectious disease that began to spread at the end of 2019. It has caused damage to multiple organs particularly human respiratory tract. Oral lesions is considered...
2022, 43(8): 161-165.
doi: 10.12259/j.issn.2095-610X.S20220826
Abstract:
Smad4 protein binds to the TGF-β type I receptor（TβR I） on transforming growth factor-β（TGF-β） and activates it. The TGF-β/Smads signaling pathway is known to play a key role in the maturation, function, and precise connectivity of vomeronasal sensor...
Smad4 protein binds to the TGF-β type I receptor（TβR I） on transforming growth factor-β（TGF-β） and activates it. The TGF-β/Smads signaling pathway is known to play a key role in the maturation, function, and precise connectivity of vomeronasal sensor...
2022, 43(8): 166-172.
doi: 10.12259/j.issn.2095-610X.S20220827
Abstract:
Objective To explore the application effect of PBL and evidence-based teaching method in clinical teaching of nursing students in emergency department. Method A total of 100 nursing students who practiced in the emergency department of a level A tert...
2022, 43(8): 173-177.
doi: 10.12259/j.issn.2095-610X.S20220828
Abstract:
Objective To analyze the training effect of the mixed curriculum construction of clinical four handed dentistry skills for stomatological students under the background of public health emergencies, so as to provide basis for stomatological undergradu...
2022, 43(8): 178-183.
doi: 10.12259/j.issn.2095-610X.S20220829
Abstract:
Objective To qualitatively analyze the needs of health education for dysphagia in nasopharyngeal carcinoma patients undergoing radiotherapy by using KANO model, and provide the basis for optimizing the health education. Methods Based on the KANO mod...
2022, 43(8): 184-190.
doi: 10.12259/j.issn.2095-610X.S20220830
Abstract:
Objective To explore the risk factors of readmission in patients with AECOPD and develop a disease risk prediction model, aiming to provide an evaluation tool for early identification and screening of patients at high risk of readmission with AECOPD....
