2022 Vol. 43, No. 9
2022, 43(9): 1-6.
doi: 10.12259/j.issn.2095-610X.S20220915
Abstract:
Objective To investigate the effects of miR-125a-3p inhibitors on the atherosclerotic plaque formation, M1/M2 macrophages, MMP-9 and VEGF. Methods Fifteen healthy adult male Japanese big-eared rabbits were randomly divided into 3 groups with 5 rabbit...
2022, 43(9): 7-12.
doi: 10.12259/j.issn.2095-610X.S20220928
Abstract:
Objective To investigate the effects of dose-response and time-dependent of endotoxin on the proliferation of human umbilical cord mesenchymal stem cells(hUC-MSCs). Methods The hUC-MSCs were cultured in stem cell culture medium containing different c...
2022, 43(9): 13-18.
doi: 10.12259/j.issn.2095-610X.S20220923
Abstract:
Objective To analyze the significance of PD-L1, BRAFV600E, CD68 protein expressions and tumor infiltrating lymphocytes (TIL) in the diagnosis of malignant melanoma. Methods High-throughput tissue microarray technology and immunohistochemical methods...
2022, 43(9): 19-23.
doi: 10.12259/j.issn.2095-610X.S20220913
Abstract:
Objective To provide the guidance for the management of patients with Alzheimer’s disease (AD) and mild cognitive impairment (MCI) by analyzing the similarities and differences between them. Methods The Neuropsychiatric Inventory (NPI) was used to a...
2022, 43(9): 24-28.
doi: 10.12259/j.issn.2095-610X.S20220901
Abstract:
Objective To find simple and reliable clinical quantitative indicators for the early diagnosis of SAE. Methods Seventy-two septic patients who were admitted to ICU from April 2020 to April 2022, including 31 with sepsis encephalopathy (SAE) and 41 w...
2022, 43(9): 29-33.
doi: 10.12259/j.issn.2095-610X.S20220905
Abstract:
Objective To investigate the relationships of matrix metalloproteinase-1 (MMP-1), matrix metalloproteinase-3 (MMP-3), matrix metalloproteinase-9 (MMP-9) and serum amyloid A (SAA) with the premature rupture of membranes. Methods Thirty cases of prema...
Study on the Correlation between Late-onset Breast Milk Jaundice and Defecation Frequency in Infants
2022, 43(9): 34-37.
doi: 10.12259/j.issn.2095-610X.S20220925
Abstract:
Objective To analyze the correlation factors of late-onset breast-feeding jaundice (LBMJ), and provide the reference for the study of LBMJ etiology. Methods 102 full-term breast-fed infants aged 0-6 months from the First Affiliated Hospital of Kunmi...
2022, 43(9): 38-42.
doi: 10.12259/j.issn.2095-610X.S20220908
Abstract:
Objective To investigate the value of angle of progression progression (AOP), fetal head descent distance (PD) and fetal head to pubic symphysis (HSD) in predicting the mode of delivery during the active phase of the first stage of labor. Methods Th...
2022, 43(9): 43-47.
doi: 10.12259/j.issn.2095-610X.S20220927
Abstract:
Objective To analyze and study the genotyping and drug resistance mutation sites of hepatitis B patients with low viral load in Kunming, so as to determine the difficulty of clinical antiviral treatment for low viral load hepatitis B patients and for...
2022, 43(9): 48-52.
doi: 10.12259/j.issn.2095-610X.S20220929
Abstract:
Objective To investigate the association between neonatal Hyperthyrotropinemia (HT) and perinatal risk factors. Methods A case-control study was conducted among 109 newborns with HT (case group) and 127 newborns without HT (control group) in the Fir...
2022, 43(9): 53-58.
doi: 10.12259/j.issn.2095-610X.S20220924
Abstract:
Objective To explore the correlation of early serum uric acid fluctuations in patients after the bariatric surgery. Methods From January 2021 to June 2022, 80 patients with the metabolic syndrome who were admitted to Yan'an Hospital of Kunming and c...
2022, 43(9): 59-65.
doi: 10.12259/j.issn.2095-610X.S20220910
Abstract:
Purpose To investigate whether a virtual reality game can reduce the chronic nonspecific low back pain and help patients recover. Methods In this randomized controlled trial, the patients with the chronic nonspecific low back pain were taken as the ...
2022, 43(9): 66-69.
doi: 10.12259/j.issn.2095-610X.S20220926
Abstract:
Objective To study the clinical therapeutic effect of doxazosin mesylate on female patients with overactive bladder (OAB) complicated with micturition symptoms. Methods A retrospective analysis was made of 68 female patients who were diagnosed with ...
2022, 43(9): 70-76.
doi: 10.12259/j.issn.2095-610X.S20220912
Abstract:
Objective To analyze PLA2G1B gene expression, prognosis, immunologic features and potential therapeutic effects in patients with lung adenocarcinoma, based on the data-mining of public databases. Methods Data from TCGA and GEO database of LUAD were ...
2022, 43(9): 77-83.
doi: 10.12259/j.issn.2095-610X.S20220920
Abstract:
Objective To analyze the clinical effect of multimodality microsurgery on recurrent gliomas, and to explore the diagnosis and treatment of recurrent gliomas. Methods Data of 28 patients with recurrent GLIOMAS who underwent reoperation from September ...
2022, 43(9): 84-89.
doi: 10.12259/j.issn.2095-610X.S20220904
Abstract:
Objective To explore the risk factors of hypoparathyroidism (HypoPT) after thyroidec-tomy and analyze the relationship between the number of coexisting risk factors and the incidence of HypoPT, so as to guide the clinical treatment. Methods A total...
2022, 43(9): 90-95.
doi: 10.12259/j.issn.2095-610X.S20220917
Abstract:
Objective To explore the application value of multi-mode ultrasound in post-liver transplantation monitoring by combining two-dimensional gray scale ultrasound, CDFI, Spectral Doppler and CEUS in gray scale, blood flow and microperfusion examination ...
2022, 43(9): 96-100.
doi: 10.12259/j.issn.2095-610X.S20220919
Abstract:
Objective To investigate the curative effect of sinus enlargement and opening partial middle turbinate resection combined with nerve branch block in patients with refractory sinusitis. Methods A total of 60 patients with refractory sinusitis admitt...
2022, 43(9): 101-106.
doi: 10.12259/j.issn.2095-610X.S20220909
Abstract:
Objective To explore the influence and relationship of prepregnancy weight and pregnancy weight gain on pregnancy complications and adverse pregnancy outcomes, and to provide the evidence for the pregnancy health care, reducing pregnancy complication...
2022, 43(9): 107-113.
doi: 10.12259/j.issn.2095-610X.S20220906
Abstract:
Objective To investigate the effect of double row suture fixation on avulsion fracture of anterior cruciate ligament (ACL) tibial insertion under arthroscopy. Methods A total of 35 patients with avulsion fracture of anterior cruciate ligament tibial...
2022, 43(9): 114-117.
doi: 10.12259/j.issn.2095-610X.S20220921
Abstract:
Objective The purpose of this study is to analyze whether mild thrombocytopenia is associated with an increased risk of postpartum hemorrhage in women undergoing cesarean section. Methods All women who underwent cesarean section in the department of...
2022, 43(9): 118-124.
doi: 10.12259/j.issn.2095-610X.S20220914
Abstract:
Objective To investigate the diagnosistic efficiency of digital breast tomosynthesis (DBT) in breast diseases. Methods 151 women with a clinically suspicious breast disease during Sept. 2017 to Sept. 2019 were enrolled into the study and all of the...
2022, 43(9): 125-129.
doi: 10.12259/j.issn.2095-610X.S20220931
Abstract:
Objective To understand the vitamin D nutritional status of pregnant women and infants in Kunming by analyzing the serum level of 25 hydroxyvitamin D(25OHD), and to explore the relationship between vitamin D and the risk of gestational diabetes so as...
2022, 43(9): 130-134.
doi: 10.12259/j.issn.2095-610X.S20220918
Abstract:
Objective To explore the efficacy and safety of white noise on improving the subjective sleep quality of soldiers in plateaus. Methods At a garrison of 3,800 meters, the Pittsburgh Sleep Assessment Scale (PSQI scale), anxiety self-assessment scale ...
2022, 43(9): 135-140.
doi: 10.12259/j.issn.2095-610X.S20220907
Abstract:
Objective To investigate the effects of vitamin D supplementation on thyroid function, autoimmune antibody and serum 25 (OH) D levels in female patients with autoimmune thyroiditis (AT) in the reproductive age. Methods 94 childbearing age females wi...
2022, 43(9): 141-146.
doi: 10.12259/j.issn.2095-610X.S20220930
Abstract:
Objective To investigate the effect of ranibizumab and odix on the microvascular structure of the macular region in patients with retinal vein occlusion-macular edema (RVO-ME). Methods All patients with RVO-ME admitted and diagnosed in the ophthalmo...
2022, 43(9): 147-154.
doi: 10.12259/j.issn.2095-610X.S20220916
Abstract:
Objective To develop a LC-MS/MS method for the determination of scopolamine and atropine in human blood and urine after Datura stramonium poisoning. Methods Shim-pack GISR-HP C18 column was used for gradient elution with acetonitrile formic acid (0....
2022, 43(9): 155-159.
doi: 10.12259/j.issn.2095-610X.S20220911
Abstract:
S-nitrosylation modification is a selective and reversible post-translational modification of protein by high concentration of nitric oxide (NO), which is related to a variety of cellular processes and tissue homeostasis. Most digestive system tumors...
S-nitrosylation modification is a selective and reversible post-translational modification of protein by high concentration of nitric oxide (NO), which is related to a variety of cellular processes and tissue homeostasis. Most digestive system tumors...
2022, 43(9): 160-165.
doi: 10.12259/j.issn.2095-610X.S20220903
Abstract:
Placenta plays an important role in the process of glucose transfer from maternal to fetus. The normal structure and function of the placenta guarantee the fetus to take up glucose effectively from maternal side over the gestation. Glucose transplace...
Placenta plays an important role in the process of glucose transfer from maternal to fetus. The normal structure and function of the placenta guarantee the fetus to take up glucose effectively from maternal side over the gestation. Glucose transplace...
2022, 43(9): 166-171.
doi: 10.12259/j.issn.2095-610X.S20220902
Abstract:
Objective To explore the effect of TBL-PBL-CBL combined teaching mode in the clinical practice of cardiology, and provide a new training direction for high-quality doctors. Methods 80 students participating in the clinical practice in the Cardiology...
2022, 43(9): 172-176.
doi: 10.12259/j.issn.2095-610X.S20220922
Abstract:
Objective To explore the effect of continuous nursing intervention for discharged stroke patients based on FOCUS-PDCA procedure. Methods 100 patients with cerebral apoplexy who were about to be discharged from our hospital from May 2020 to February ...