2023 Vol. 44, No. 7
2023, 44(7): 1-8.
doi: 10.12259/j.issn.2095-610X.S20230723
Abstract:
Objective To investigate the effects of Euonymine on isolated cultured human umbilical vein endothelial cells (HUVECs) and human vascular smooth muscle cells (VSMCs), so as to elucidate the possible mechanism of Euonymine in prevention and treatment ...
2023, 44(7): 9-15.
doi: 10.12259/j.issn.2095-610X.S20230710
Abstract:
Objective To evaluate the clinical application value of nanopore sequencing in tumor patients with concurrent infectious diseases and to provide a new detection method for rapid and sensitive diagnosis of infectious diseases in tumor patients. Metho...
2023, 44(7): 16-21.
doi: 10.12259/j.issn.2095-610X.S20230702
Abstract:
Objective To analyze the screening results and genotype distribution characteristics of glucose-6-phosphate dehydrogenase (G6PD) deficiency among Dai people in Yingjiang County, Yunnan Province, and to provide a scientific theoretical basis for its p...
2023, 44(7): 22-28.
doi: 10.12259/j.issn.2095-610X.S20230711
Abstract:
Objective To analyze the relationship between endoplasmic reticulum aminopeptidases (ERAP) gene polymorphisms and serum polio antibodies induced by sequential polio vaccine immunization. Methods A total of 243 Zhuang individuals were selected from t...
2023, 44(7): 29-33.
doi: 10.12259/j.issn.2095-610X.S20230717
Abstract:
Objective To explore the relationship between DNA damage and urinary arsenic metabolism in four genes of EGFR, PTEN, Kras and PIK3CA in workers exposed to arsenic in arsenic factories. Methods A total of 78 first-line occupational arsenic exposure w...
2023, 44(7): 34-39.
doi: 10.12259/j.issn.2095-610X.S20230701
Abstract:
Objective To explore the potential mechanism of Osteoking (OK) in the treatment of Osteoarthritis (OA) and preliminarily verify it with DMM rats. Methods TCMSP database was used to collect potential targets of OK, GeneCards database and OMIM were us...
2023, 44(7): 40-46.
doi: 10.12259/j.issn.2095-610X.S20230704
Abstract:
Objective To investigate the self-rated health status of elderly hypertensive patients in rural areas of Yi people, Yunnan province, and explore the influencing factors. Methods A convenience sample of 980 elderly hypertensive patients from rural ar...
2023, 44(7): 47-51.
doi: 10.12259/j.issn.2095-610X.S20230706
Abstract:
Objective To investigate the prognosis of surgical resection in patients with nonfunctioning pancreatic neuroendocrine neoplasms (NF-pNENs). Methods The clinical and follow-up data of 45 patients who were pathologically confirmed NF-pNENs in the Sec...
2023, 44(7): 52-56.
doi: 10.12259/j.issn.2095-610X.S20230718
Abstract:
Objective To determine the characteristics of Tibetan patients with orthodontic treatment in Shangri-la of Diqing prefecture, and provide scientific evidence for dentists. Methods 249 Tibetan orthodontic patients (90 males and 136 females) between t...
2023, 44(7): 57-63.
doi: 10.12259/j.issn.2095-610X.S20230713
Abstract:
Objective To explore the role of four-dimensional left atrial automatic quantitative technology in evaluating the volume and function of the left atrium in non-selective continuous patients, and to preliminarily explore its accuracy and repeatability...
2023, 44(7): 64-68.
doi: 10.12259/j.issn.2095-610X.S20230727
Abstract:
Objective To analyze the clinical risk factors in idiopathic hypogonadotropic hypogonadism patients (IHH). Methods We selected 120 patients with hypogonadism from the Endocrinology Department of the First People's Hospital of Yunnan Province from Ja...
2023, 44(7): 69-77.
doi: 10.12259/j.issn.2095-610X.S20230724
Abstract:
Objective To investigate the effects of M2 macrophage-derived exosome miR-1246 on the proliferation, apoptosis and invasion of AGS cells. Methods After induction of M2 macrophages using LPS and IFN-γ, their exosomes were isolated and identified by t...
2023, 44(7): 78-87.
doi: 10.12259/j.issn.2095-610X.S20230716
Abstract:
Objective To investigate the prognostic risk factors of patients with septic shock based on circulatory and cellular immune effects, to accurately regulate the noradrenaline dose, alleviate immune function suppression, and improve the success rate of...
2023, 44(7): 88-93.
doi: 10.12259/j.issn.2095-610X.S20230707
Abstract:
Objective To investigate the correlation between pulmonary function and respiratory muscle strength in adolescent idiopathic scoliosis (AIS) patients compared to healthy subjects of the same age, and to investigate the correlation between the size of...
2023, 44(7): 94-99.
doi: 10.12259/j.issn.2095-610X.S20230709
Abstract:
Objective To investigate the mechanisms of intestinal barrier damage after heroin withdrawal by analyzing changes in markers of intestinal barrier damage at different withdrawal times, providing a new direction for the relationship between altered ps...
2023, 44(7): 100-104.
doi: 10.12259/j.issn.2095-610X.S20230725
Abstract:
Objective To investigate the pharmacokinetics of dexmedetomidine in burn patients with different degrees in order to improve the quality of anesthesia in burn patients. Methods Forty-five burn patients undergoing elective surgery were selected in th...
2023, 44(7): 105-112.
doi: 10.12259/j.issn.2095-610X.S20230722
Abstract:
Objective To understand the occupational exposure situation of staff in the pharmacy intravenous admixture services (PIVAS) of Yunnan Province and identify the issues related to occupational protection in PIVAS staff. Methods Based on the “Quality M...
2023, 44(7): 113-118.
doi: 10.12259/j.issn.2095-610X.S20230721
Abstract:
Objective To investigate the effects of combined subanesthetic doses of esketamine and propofol anesthesia in three-dimensional after loading treatment of cervical cancer. Methods One hundred patients who received three-dimensional afterloading tre...
2023, 44(7): 119-124.
doi: 10.12259/j.issn.2095-610X.S20230703
Abstract:
Objective To observe the effects of rTMS on cognitive function in patients with traumatic brain injury. Methods A total of 160 patients with traumatic brain injury admitted to Yan’an Hospital of Kunming City from January 2021 to January 2022 were se...
2023, 44(7): 125-129.
doi: 10.12259/j.issn.2095-610X.S20230720
Abstract:
Objective To study the growth factors and its contents in the concentrated growth factor (CGF) fibrin gel for type 2 diabetes mellitus (T2DM). Methods T2DM patients who needed tooth extraction and implantation under insulin hypoglycemic were selecte...
2023, 44(7): 130-135.
doi: 10.12259/j.issn.2095-610X.S20230715
Abstract:
Objective To investigate the influencing factors of preeclampsia to provide basis for prediction and treatment of preeclampsia. Methods In Qujing Maternal and Child-care Hospital, 11679 pregnant women who were included in the prospective cohort of m...
2023, 44(7): 136-141.
doi: 10.12259/j.issn.2095-610X.S20230705
Abstract:
Objective To investigate the diagnostic value of AFP-L3 and PIVKAⅡ in liver cancer. Methods A total of 3066 patients with chronic liver disease who were admitted to Qingdao Sixth People’s Hospital from January 2019 to January 2022 were selected as o...
2023, 44(7): 142-147.
doi: 10.12259/j.issn.2095-610X.S20230726
Abstract:
Objective To understand the psychological status of the elderly, through a survey of the elderly in Chengdu, to explore the correlation between the different psychological status of the elderly, to find the cut-in point for the related departments to...
2023, 44(7): 148-155.
doi: 10.12259/j.issn.2095-610X.S20230708
Abstract:
Pediatric non-alcoholic fatty liver disease (NAFLD) is the most common cause of pediatric chronic liver disease worldwide, and its incidence is gradually increasing with the global epidemic of obesity, but there is no standardized and effective treat...
Pediatric non-alcoholic fatty liver disease (NAFLD) is the most common cause of pediatric chronic liver disease worldwide, and its incidence is gradually increasing with the global epidemic of obesity, but there is no standardized and effective treat...
2023, 44(7): 156-161.
doi: 10.12259/j.issn.2095-610X.S20230719
Abstract:
Heart failure is one of the main causes of death in cardiovascular diseases. With the increasing prevalence of heart failure, it has become the main research direction to explore new therapeutic targets and further reduce the mortality of patients. T...
Heart failure is one of the main causes of death in cardiovascular diseases. With the increasing prevalence of heart failure, it has become the main research direction to explore new therapeutic targets and further reduce the mortality of patients. T...
2023, 44(7): 162-167.
doi: 10.12259/j.issn.2095-610X.S20230728
Abstract:
NASH is the characteristic pathological manifestation of the liver in MAFLD, which is a key turning point in the development of MAFLD from a relatively benign and reversible stage to liver injury and even cirrhosis and hepatocellular carcinoma. Recen...
NASH is the characteristic pathological manifestation of the liver in MAFLD, which is a key turning point in the development of MAFLD from a relatively benign and reversible stage to liver injury and even cirrhosis and hepatocellular carcinoma. Recen...
2023, 44(7): 168-172.
doi: 10.12259/j.issn.2095-610X.S20230714
Abstract:
Objective To understand the distribution of Kolb learning style of medical students and analyze its influencing factors, so as to provide a theoretical basis for the reform of medical teaching. Methods Kolb Learning style Scale and 10 related factor...
2023, 44(7): 173-176.
doi: 10.12259/j.issn.2095-610X.S20230712
Abstract:
Objective To explore the role of case-based collaborative learning (CBCL) in the standardized training of residents. Methods All 64 residents included in this study were randomly divided into two groups: the experimental group (n = 32) and the cont...