2022 Vol. 43, No. 1

Original Articles Basic of Medicine
Methamphetamine Alters Methylation Modifications of Synaptic Plasticity Genes in Addicted Mice
Junhong MAO, Danfeng LU, Yu XU, Yicong DAI, Zherui ZHANG, Yue LI, Kunhua WANG
2022, 43(1): 1-7. doi: 10.12259/j.issn.2095-610X.S20220121
Abstract(3194) HTML PDF(158)
Abstract:
Objective To investigate the expression changes of synaptic plasticity genes in chronic methamphetamine (MA) addicted mice. Methods C57BL/6J mice were selected to simulate the human drug addiction model, and the drugs were injected intraperitoneally...
Iodine-125 Seed Inhibits the Proliferation and Invasion of Gastric Cancer Cells by Regulating MicroRNA-193b-5p Expression
Zhenhuan MA, Zhen LI, Xianglin ZHOU, Guojian LI, Guokai YANG, Jia WAN, Lingjuan DU, Yong YANG
2022, 43(1): 8-13. doi: 10.12259/j.issn.2095-610X.S20220120
Abstract(4252) HTML PDF(32)
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Objective To investigate the role of microRNA (miRNA, miR)-193b-5p in the process of iodine-125 particle radiotherapy for gastric cancer. Methods Gastric cancer cell line BGC-823 was used as the research object and iodine-125 seed in vitro irradiati...
Effects of Micafungin on the Activity of Candida Smooth in Macrophages
Weijia ZHAO, Hongbin LI, Zonghan CHEN
2022, 43(1): 14-19. doi: 10.12259/j.issn.2095-610X.S20220142
Abstract(3629) HTML PDF(20)
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Objective To investigate the effects of micafungin on the activity of Candida glabra in macrophages. Methods Macrophages were selected as the research object, and samples were isolated from the skin, vaginal secretion, pus, blood and body cavity flu...
Studies on Cisplatin Resistance of miR-181a in Ovarian Cancer Cells
Lixiu XU, TUERXUN Meiliban, YAKUFU Kereman
2022, 43(1): 20-25. doi: 10.12259/j.issn.2095-610X.S20220131
Abstract(3500) HTML PDF(35) Cited By (1)
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Objective To investigate the effect of miR-181a on chemotherapy resistance of ovarian cancer and its regulatory mechanism. Methods Real-time PCR was used to detect the expression of miR-181a in A2780 and cisplatin resistant cell lines (A2780/DDP), a...
Platelet-rich Plasma Promotes the Proliferation of Human Endometrial Mesenchymal Stem Cells (EnMSCs) through the PI3K/AKT/mTOR Signaling Pathway
Xiaohan WANG, Shanmao MOU, Cuifang HAO, Linlin REN, Min WANG, Tong ZHAO
2022, 43(1): 26-32. doi: 10.12259/j.issn.2095-610X.S20220126
Abstract(4336) HTML PDF(48) Cited By (8)
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Objective To explore the mechanism of PRP promoting EnMSCs proliferation, and to provide a theoretical basis for the expansion and clinical application of EnMSCs. Methods EnMSCs were randomly divided into the control group, 2%PRP group and 2%PRP + ...
The Analysis of Alcohol Dependence Degree and Influencing Factors in Male Alcohol Dependence Patients
Tingting ZENG, Zuxing FENG, Jing YUAN, Li WU, Changjiang WU, Li XU, Fang ZHOU, Xin WANG, Yuxiong JIN, Junyu MENG, Huizuo FU, Jianzhong YANG
2022, 43(1): 33-39. doi: 10.12259/j.issn.2095-610X.S20220103
Abstract(5140) HTML PDF(130) Cited By (14)
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Objective To explore the cognition, mood, sleep status and alcohol dependence degree of patients with alcohol dependence and its influencing factors. Methods In a cross-sectional study, alcohol dependent patients hospitalized in the psychiatric depa...
Epidemiological Analysis of Clinical Isolation of Multi-drug Resistant Bacteria in Children’ s Hospitals
Liqin CHEN, Yaling LI, Xiaojuan LI, Yonghui HAN, Weijie LI
2022, 43(1): 40-47. doi: 10.12259/j.issn.2095-610X.S20220105
Abstract(4022) HTML PDF(32) Cited By (4)
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Objective To analyze the distribution and characteristics of multi-drug-resistant bacteria isolated from the clinic in a children’ s hospital, providing the clinical evidence for the prevention and treatment of multi-drug-resistant bacteria in the ho...
Clinical Research
Analysis of Chemerin Expression and IRS-1 and Tyrosine Phosphorylation in Omental Adipose Tissue of GDM Pregnant Women
Xiaohong LI, Lin ZHAO, Xinwen ZHANG, Zhuo CHEN, Runmei MA
2022, 43(1): 48-52. doi: 10.12259/j.issn.2095-610X.S20220140
Abstract(3934) HTML PDF(103) Cited By (1)
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Objective To investigate the relationship between chemerin and insulin resistance in GDM by detecting the expression of insulin receptor substrate-1 and tyrosine phosphorylation in omental adipose tissue. Methods Subjects were divided into the GDM gr...
Clinical Features and Related Prognostic Factors of 88 Cases of Duodenal Adenocarcinoma
Zhengqin GENG, Lin XIE, Hongli SONG, Rong LI, Yedan LIAO, Xueqi ZhANG, Jiadai TANG
2022, 43(1): 53-58. doi: 10.12259/j.issn.2095-610X.S20220109
Abstract(5005) HTML PDF(41) Cited By (1)
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Objective To analyze the clinical characteristics and related prognostic factors of patients with duodenal adenocarcinoma. Methods 88 patients with duodenal adenocarcinoma who were pathologically diagnosed and admitted to Yunnan Cancer Hospital from...
The Application of Breviscapine on Graft Restenosis in Coronary Artery Bypass Grafting
Hu ZHANG, Anrui PENG, Jiaji ZHONG, Bo HUANG, Peng BAI
2022, 43(1): 59-62. doi: 10.12259/j.issn.2095-610X.S20220136
Abstract(4111) HTML PDF(21)
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Objective To explore the protective effect of breviscapine on graft vein grafting in the patients who underwent Coronary Artery Bypass Graft (CABG). Methods According to the inclusion criteria and exclusion criteria, 64 patients entered the study an...
Studies on the Correlation between Serum Vitamin A, D and Lung Function in Infants with Asthmatic Pneumonia
Linxia LI, Yanhong LI, Jie WU, Lili ZHANG, Xian ZHANG, Song WANG, Juntao ZHANG, Peng YAN
2022, 43(1): 63-66. doi: 10.12259/j.issn.2095-610X.S20220114
Abstract(4234) HTML PDF(99) Cited By (5)
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Objective To understand the serum levels of 25-hydroxyvitamin D [25 (OH) D] and vitamin A in infants with asthmatic pneumonia during the onset of pneumonia, so as to analyze their correlation with lung function and serum Ig E and to further discover ...
Dosimetric Differences between Tomo and Monaco Planning Systems and Comparison of Gamma Pass Rates in Preoperative Radiotherapy for Rectal Cancer Patients
Hao YAN, Qi YUE, Dan GU, Hui TIAN, Hui LI, Rongqing LI
2022, 43(1): 67-72. doi: 10.12259/j.issn.2095-610X.S20220132
Abstract(2961) HTML PDF(18) Cited By (1)
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Objectives To investigate the dosimetric differences between TOMO and Monaco planning systems in preoperative radiotherapy for rectal cancer and the comparison of Gamma pass rate, so as to provide a reference for the selection of clinical treatment. ...
The Correlation between The Thyroid Function and Renal Function in Patients with Differentiated Thyroid Cancer under the Short-term Hypothyroidism after Withdrawal of Iodine Therapy
Feipeng WU, Yongqiang GAO, Liju HONG, Qiyan WU, Huijun CHENG, Jiaoxia LI, Youjun ZHOU, Xiandong ZHENG
2022, 43(1): 77-83. doi: 10.12259/j.issn.2095-610X.S20220128
Abstract(3106) HTML PDF(26) Cited By (8)
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Objectives To investigate the correlation between the thyroid function and renal function in patients with the differentiated thyroid cancer in the short-term hypothyroid state after the discontinuation of prior radioiodine therapy. Methods A total ...
The Currative Effect of Biological Lengthened Handle Total Hip Arthroplasty in the Treatment of Subtrochanteric Fracture Combined with Femoral Head Necrosis
Jiahui CHEN, Biao LI, Yi YANG, Shufa WEI, Junhong LIU, Yiming LIANG, Xin ZENG, Nanxi LI
2022, 43(1): 84-88. doi: 10.12259/j.issn.2095-610X.S20220104
Abstract(2964) HTML PDF(48) Cited By (4)
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Objective To investigate the feasibility and clinical effect of total hip replacement with the biologically lengthened stem in the treatment of subtrochanteric fractures combined with the necrosis of femoral head. Methods A total of 88 patients admi...
The Effect of Bronchoscopic Alveolar Lavage on the Maintenance of Borderline Donor Lung in Brain Death
Lingming GONG, Li LI, Jianghua RAN, Lan LI, Shengning ZHANG, Chao LI, Yinjia WANG, Dongkun WANG, Li ZHENG, Guofeng ZHANG
2022, 43(1): 89-95. doi: 10.12259/j.issn.2095-610X.S20220107
Abstract(2765) HTML PDF(24) Cited By (5)
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Objective To investigate the effect of bronchoscopic alveolar lavage on the maintenance of borderline donor lung in brain death. Methods The brain death patients meeting the inclusion criteria and admitted to Ganmei Hospital of Kunming Medical Unive...
The Regularity and Clinical Manifestations of Throat Swab and Fecal Detoxification in New Coronavirus Infected Patients
Ying HUANG, Yun LUO, Yan WU, Bing LIU, Shan JIANG, Hua HE
2022, 43(1): 96-101. doi: 10.12259/j.issn.2095-610X.S20220112
Abstract(4363) HTML Cited By (1)
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Objective To explor the clinical characteristics and detoxification rules of the patients with COVID-19 nucleic acid positive by analyzing their clinical manifestations of throat swabs and fecal, so as to provide the evidence for the clinical diagnos...
Studies on the Prognosis between Serum sST2 Level and Coronary Heart Disease
Shuo WANG, Yunyan QI, Pu WANG, Yaru WANG, Xiaochan ZHANG, Liu LI
2022, 43(1): 112-117. doi: 10.12259/j.issn.2095-610X.S20220115
Abstract(4374) HTML Cited By (7)
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Objective This study was to analyze the prognosis between soluble growth stimulation expressed gene 2 protein ( sST2 ) and the severity of coronary heart disease. Methods 400 patients who needed coronary angiography and stent implantation were selec...
AIDS Research
Investigations on the Infection, Immunity and Drug Resistance of Newly-treated Cases of HIV in Kunming
Tingting YU, Dongling LI, Hongying WANG, Lihua LI, Dong PU, Kunli WU
2022, 43(1): 138-143. doi: 10.12259/j.issn.2095-610X.S20220133
Abstract(4144) HTML PDF(26) Cited By (2)
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Objective To investigate the infection, immunity, and drug resistance of newly-treated HIV cases in Kunming. The clinical characteristics and virological characteristics were jointly analyzed, so as to provide a basis to determine the ease of treatme...
Reviews
Research Progress of Zinc Finger Protein and Hepatocellular Carcinoma
Heng ZHANG, Cheng ZHANG, Weiran LIAO, Yutao HE, Yuyang ZHANG, Bin DU, Lin WANG
2022, 43(1): 144-149. doi: 10.12259/j.issn.2095-610X.S20220135
Abstract(3918) HTML PDF(40) Cited By (1)
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Due to its complicated mechanism, the occurrence and development of hepatocellular carcinoma have not been fully revealed yet. As the largest transcription factor family in the human genome, zinc finger proteins have been confirmed to play a key role...
Research Progress of Exosomes-derived Long Non-coding RNA in Bladder Cancer
Jun GU, Zexi HE, Ting LUAN, Haifeng WANG, Jiansong WANG, Mingxia DING
2022, 43(1): 150-156. doi: 10.12259/j.issn.2095-610X.S20220110
Abstract(4180) HTML PDF(36) Cited By (1)
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Bladder cancer is one of the most common urinary tumors with the high morbidity and recurrence rate. It is of great clinical value to develop a non-invasive detection technique with the high sensitivity and specificity in vitro for the diagnosis and ...
Research Progress of Akkermansia Muciniphila and Obesity-related Metabolic Diseases
Hongjiang ZHOU, Juan TANG, Lei LIANG, Xin NIAN
2022, 43(1): 157-162. doi: 10.12259/j.issn.2095-610X.S20220143
Abstract(3755) HTML PDF(44) Cited By (1)
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The intestinal microbiota plays a vital role in regulating host immunity and energy metabolism, and is related to the occurrence of obesity, diabetes, and cardiovascular diseases. At present, various animal models and human studies have proved that A...
Teaching Research
Application of 3D Animation and Traditional Teaching in Neurotomy
Chaosheng ZENG, Shu LIU, Pengxiang LI, Min CHEN, Lin CHEN
2022, 43(1): 163-166. doi: 10.12259/j.issn.2095-610X.S20220102
Abstract(3538) HTML PDF(29) Cited By (6)
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Objective To explore the application and research of 3D animation and traditional teaching in neurotomy. Methods 240 first-year undergraduates of clinical medicine at our college were enrolled as the research objects, and the teaching period was fro...
Nursing Forum
Construction and Application of Node Health Education Model Based on Health Information Needs of Patients Undergoing in Vitro Fertilization-embryo Transfer
Hengman ZHU, Zhenfang SU, Huawei WANG, Ju TANG, Congfei ZHANG, Qingmei LIU, LIUYinghong, Jianmei GAO, Meng RAO
2022, 43(1): 167-172. doi: 10.12259/j.issn.2095-610X.S20220146
Abstract(3124) HTML PDF(11) Cited By (9)
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Objective To construct and apply the health education model for in vitro fertilization-embryo transfer (IVF-ET) assisted patient node based on health information needs, and to evaluate its effect. Method Cases studied were divided into the control g...