2020 Vol. 41, No. 12

Clinical Study of Chemotherapy Combined with CIK Cell Immunotherapy for Non-small Cell Lung Cancer
Xiao-biao MA, Feng LUO, Yong-liang GAO, Jing-chao HAO
2020, 41(12): 60-67. doi: 10.12259/j.issn.2095-610X.S20201215
Abstract(3693) HTML PDF(40) Cited By (7)
Abstract:
Objective To evaluate the clinical efficacy of chemotherapy combined with CIK (cytokine-induced killer)cell immunotherapy on early and advanced stages non small cell lung cancer (NSCLC)patients. Methods A total of 122 NSCLC patients admitted to the...
Diagnostic Efficacy of Serum PIVKA-Ⅱ Detection in Primary Hepatocellular Carcinoma
Li-xian YUAN, Hong-tao ZHANG, Rui LI, Kun-rui CHEN, Kun-qian CHEN, An-shu XU
2020, 41(12): 80-84. doi: 10.12259/j.issn.2095-610X.S20201223
Abstract(3401) HTML PDF(31) Cited By (7)
Abstract:
Objective To explore the diagnostic efficacy of serum Protein induced by vitamin K absence or antagonist-Ⅱ(PIVKA-Ⅱ)in Primary hepatocellular carcinoma. Methods 150 patients who diagnosed and treated in Qujing Affiliated Hospital of Kunming Medical ...
Evaluation of Peripheral Blood Cytokine Levels before and after Psoriasis Treatment with Narrow-spectrum UVB Combined with Carpotriol
Wei-jia ZHAO, Hong-bin LI, Zong-han CHEN
2020, 41(12): 99-103. doi: 10.12259/j.issn.2095-610X.S20201227
Abstract(3190) HTML PDF(20) Cited By (10)
Abstract:
Objective To analyze the clinical efficacy of narrow-spectrum UVB in the treatment of psoriasis and the effect on peripheral blood cytokines. Methods 109 patients with psoriasis treated in the First Affiliated Hospital of Kunming Medical University...
Comparison of Different Doses of Amphotericin B Intrathecal Injection Combined with Continuous Cerebrospinal Fluid Drainage Replacement in the Treatment of Cryptococcal Meningitis
Hua HE, Ying HUANG, Yan-ling ZHANG, Jun XU, Wen-ming LI, Yun LUO
2020, 41(12): 112-118. doi: 10.12259/j.issn.2095-610X.S20201230
Abstract(3198) HTML PDF(23) Cited By (3)
Abstract:
Objective To investigate the efficacy and side effects of different doses of amphotericin B intrathecal injection in the treatment of cryptococcal meningitis. Methods 69 cases of cryptococcal meningitis admitted in the Third People's Hospital of Ku...
Efficacy of T-SPOT.TB in Treatment of Active Tuberculosis
Rong WAN, Ming-wu LI, Meng MA, Ming-hong LAI, Guang-mei Li
2020, 41(12): 133-137. doi: 10.12259/j.issn.2095-610X.S20201237
Abstract(3082) HTML PDF(30) Cited By (4)
Abstract:
Objective To explore the significance of T-SPOT.TB test for monitoring the therapeutic effect of tuberculosis. Methods Using T-SPOT.TB kit, changes in response to ESAT-6 and CFP-10 were compared in 79 patients with active pulmonary tuberculosis bef...
Efficacy of Case-based Teaching in Medical Genetics Course
Yan-jie ZHANG, Lu ZHANG, Yan-rui WU, Yu-ling YANG, Zhi-xiang FAN, Yuan-xiao CHEN, Yao LI, Li LONG
2020, 41(12): 160-163. doi: 10.12259/j.issn.2095-610X.S20201243
Abstract(3248) HTML PDF(29) Cited By (3)
Abstract:
Objective To explore the efficacy of case-based teaching in medical genetics course. Method The whole class majoring Pediatrics in 2018 batch was the experimental class, and the clinical medicine students in 2018 batch are the control class. Case-t...
Significance of miRNA-21 Expression in Rabbits with High-Dose Fractional Radiation Heart Injury
Shu-hui YU, Jing-yan GAO, Biao ZHAO, Yu-tao ZHAO, Ya LI
2020, 41(12): 1-5. doi: 10.12259/j.issn.2095-610X.S20201204
Abstract(2840) HTML PDF(117) Cited By (4)
Abstract:
Objective To establish a good, reliable, and stable radiation-induced heart disease (RIHD)model, and to determine the miRNA-21 expression trend in plasma. Methods 27 adult male healthy New Zealand rabbits were randomly divided into control group (3...
Characterization of Human Body Composition in 10 913 Pregnant Women in Longyang District, Baoshan City
Hong LI, Wen-yan YANG, Yu-zhen HU, Song-yuan TANG, Bin ZHU
2020, 41(12): 6-10. doi: 10.12259/j.issn.2095-610X.S20201207
Abstract(2584) HTML PDF(23) Cited By (4)
Abstract:
Objective To characterize the difference of body mass and body composition among women in pre-pregnancy period and different pregnant stages in Longyang District, Baoshan city. Methods The body composition of 10 913 pregnant women were measured by ...
Analysis of Neck Pain and Related Factors in Medical Students
Fan-yuan MENG, Xin TANG, Mo-xian CHEN, Yang WANG, Jin-xiu LI, Wen-li BAO
2020, 41(12): 11-17. doi: 10.12259/j.issn.2095-610X.S20201208
Abstract(3153) HTML PDF(45) Cited By (2)
Abstract:
Objective To investigate the incidence and related influencing factors of neck pain in medical students, as well as the symptoms of neck pain and their impact on daily life. Methods A self-designed questionnaire was used to survey medical students ...
Study of Comparative Experiment for Self-made Foreign Body Retrieval Device and Traditional Foreign Body Retrieval Device in Simulated Human Blood Vessels
Yao LI, Hua-lin YU, Shou-wei XIANG, Peng BAI
2020, 41(12): 18-22. doi: 10.12259/j.issn.2095-610X.S20201210
Abstract(2702) HTML PDF(31)
Abstract:
Objective To compare the effect of retrieving foreign bodies for the self-made foreign body retrieval device and the traditional foreign body retrieval device in simulated human blood vessels. Methods Under the simulated general anesthesia, the mod...
Clinical Characteristics of Interstitial Pneumonia with Autoimmune Features
Zheng-cong CHEN, Zhao-xing DONG, Xiao-yuan ZHAO, Tao ZHANG
2020, 41(12): 23-28. doi: 10.12259/j.issn.2095-610X.S20201211
Abstract(3941) HTML PDF(45) Cited By (5)
Abstract:
Objective To explore the clinical features of interstitial pneumonia (IPAF) patients with autoimmune characteristics, and to compare the clinical difference between IPAF and non-IPAF-IIP (idiopathic interstitial pneumonia) and IPF (idiopathic pulmona...
Correlation between Anxiety Depression Symptoms of Patients with Chronic Obstructive Pulmonary Disease and CAT Score
He-ping LIU, Hong-mei WU, Yang LIU, Chun ZHANG, Wei-zhou WANG, Ding-yun YOU, Hong-xiang WU
2020, 41(12): 29-35. doi: 10.12259/j.issn.2095-610X.S20201212
Abstract(3816) HTML PDF(25) Cited By (18)
Abstract:
Objective To evaluate the incidence and risk factors for anxiety and/or depression in patients with chronic obstructive pulmonary disease(COPD), and to explore the correlation between the anxiety depression symptoms and CAT score of patients with COP...
Characteristics of Intestinal Microflora in Patients with Coronary Heart Disease
Hai-long DAI, Nan WANG, Xiao-qing CHEN, Zhen-yi HE, Xiao-lan FENG, Xue-feng GUANG
2020, 41(12): 36-41. doi: 10.12259/j.issn.2095-610X.S20201213
Abstract(3432) HTML PDF(29) Cited By (24)
Abstract:
Objective To analyze the composition and diversity of intestinal microflora in patients with coronary heart disease in Yunnan, and to explore the differences of intestinal microflora among different types of coronary heart disease and those without c...
Analysis of lncRNA-mRNA Co-expression Network in Invasive Pituitary Adenomas
Guo-qing JIANG, Xing-li DENG, Xiao-juan LI, Yuan QIAN
2020, 41(12): 42-48. doi: 10.12259/j.issn.2095-610X.S20201214
Abstract(2050) HTML PDF(29) Cited By (5)
Abstract:
Objective To screen differentially expressed lncRNAs in invasive pituitary adenomas by second-generation sequencing, and to explore their potential role in the pathogenesis of invasive pituitary adenomas. Methods The expressions of lncRNA and mRNA ...
Expression of Serum H-FABP, Platelet Activating Factor and IMA in Patients with Coronary Heart Disease and Its Clinical Implications
Ju TIAN, Wen-jie WANG, Qian LI
2020, 41(12): 49-54. doi: 10.12259/j.issn.2095-610X.S20201216
Abstract(2609) HTML PDF(32) Cited By (4)
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Objective To investigate the expression of serum H-FABP, platelet activating factor (PAF) and ischemia-modified albumin (IMA) in patients with coronary heart disease and its clinical implications. Methods 168 patients who reported chest pain and un...
The Diagnostic Efficacy of Alveolar Lavage Fluid G test and GM Test in AECOPD Complicated with Invasive Pulmonary Fungal Infection
Ying ZHANG, Xiao-qun NIU
2020, 41(12): 55-59. doi: 10.12259/j.issn.2095-610X.S20201217
Abstract(2823) HTML PDF(24) Cited By (5)
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Objective To evaluate the diagnostic efficacy of alveolar lavage fluid(1, 3)-beta-D-glucan(G)test and galactomannan(GM)test in early diagnosis of acute exacerbations of chronic obstructive pulmonary disease(AECOPD)complicated with invasive pulmonary ...
Expression of HPV16E6 and Indoleamine 2, 3-dioxygenase in Cervical Lesions and Its Clinical Implications
Lin-lin YANG, Chun-mei YIN, Lei ZHANG, Wei WANG, Ling-feng ZHAO, Yu-die YANG, He ZHAO, Ying LIU
2020, 41(12): 68-72. doi: 10.12259/j.issn.2095-610X.S20201219
Abstract(2646) HTML PDF(21)
Abstract:
Objective To explore the potential of HPV16E6 and IDO as a tumor markers of cervical cancer, the expression of high-risk HPV-infected normal cervical tissue, cervical precancerous lesions, cervical cancer tissue HPV16E6 and IDO, the correlation betwe...
Association between Lifestyle and Behavior and Skin Physiological Function in Patients with Chronic Pruritus
Na LI, Ying TU, Ying XIONG, Ya-jie NENG, Hong-bin LI, Hong-min LIANG
2020, 41(12): 73-79. doi: 10.12259/j.issn.2095-610X.S20201222
Abstract(2226) HTML PDF(27) Cited By (3)
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Objective By investigating the influence of chronic pruritus patients' lifestyle and behavior on skin physiological function, this paper provides basis and measures for the health management of patients with pruritus. Methods Lifestyle and behavior...
Effects of Dexmedetomidine on Respiration in Postoperative Patients Undergone General Anesthesia at High Altitude Areas
Qing-qing XIONG, Xiao-dong LUO, Bu-fang FU, Jia-yi ZHONG, Guo-lian HE
2020, 41(12): 85-88. doi: 10.12259/j.issn.2095-610X.S20201224
Abstract(3302) HTML PDF(22) Cited By (4)
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Objective To observe the effect of dexmedetomidine on respiration in postoperative patients undergone general anesthesia at high altitude areas. Methods 60 patients who received laparoscopic cholecystectomy under tracheal general anesthesia, and al...
Study on the Correlation between Vernal Keratoconjunctivitis and Dry Eye Syndrome in Children
Xiao-bo ZENG, Jiang-tao XU, Min DENG, Zheng-cui NIE, Rui-meng YUAN, Ting-yan ZHU
2020, 41(12): 89-93. doi: 10.12259/j.issn.2095-610X.S20201225
Abstract(1964) HTML PDF(19) Cited By (4)
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Objective To evaluate the condition of dry eyes in children with vernal keratoconjunctivitis in spring, and to explore the clinical characteristics as well as correlation with the severity of the disease. Method 65 children who were diagnosed with ...
A Comparative Study of the Cognitive Function in Patients with Different Degrees of Depression
Xian LI, Chang-liang JI, Shu-e ZENG, Shu-yun YANG, Hao-qi YANG, Ya-ting HOU
2020, 41(12): 94-98. doi: 10.12259/j.issn.2095-610X.S20201226
Abstract(3330) HTML PDF(25) Cited By (5)
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Objective Based on the fact that Yunnan is a remote and bordering area with multiple ethnic minorities, Wechsler intelligence Scale and Raven standard Reasoning test were used to compare the difference of cognitive function in patients with different...
Efficacy of Deside Cream Combined with Compound Polymyxin B Ointment in the Treatment of Moderate-severe Atopic Dermatitis in Children
Xin-yue CHEN, Zong-han CHEN, Wei-jia ZHAO
2020, 41(12): 104-107. doi: 10.12259/j.issn.2095-610X.S20201228
Abstract(3963) HTML PDF(24) Cited By (13)
Abstract:
Objective To analyze the efficacy of deside cream combined with compound polymyxin B ointment in the treatment of moderate-severe atopic dermatitis in children. Methods A total of 82 children with severe atopic dermatitis in the dermatology departm...
Comparative Study of Neutrophil Elastase and Total Antioxidant Capacity in Serum of COPD Patients with Different HRCT Phenotypes
Hong-bo CHEN, Li-ping CHEN, Yong-ming JIN, Li-na WANG, Li-rui ZHU, Rong-qiong SHEN
2020, 41(12): 108-111. doi: 10.12259/j.issn.2095-610X.S20201229
Abstract(3222) HTML PDF(18) Cited By (10)
Abstract:
Objective To explore the neutrophil elastase(neutrophil elastase, NE), total antioxidant capacity(total antioxidative capability, T - AOC)in chronic obstructive pulmonary disease(chronic obstructive pulmonary diseases, COPD)high-resolution CT(high-re...
Molecular Epidemiology of Human Rhinovirus in 2 260 Children with Acute Lower Respiratory Tract Infection
Li TAN, Ming LI, Yu-xing SUN, Zhen ZHANG, Zheng-yan GAN
2020, 41(12): 119-122. doi: 10.12259/j.issn.2095-610X.S20201233
Abstract(4013) HTML PDF(46) Cited By (15)
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Objective To investigate the molecular epidemiological characteristics of human rhinovirus (HRV) infection in hospitalized children with acute lower respiratory tract infection (ALRTI) in Kunming. Methods A total of 2260 children with ALRTI who wer...
Coagulation Function in Patients with Obstructive Sleep Apnea Hypopnea
Chun-Xia HE, Zhi-Juan LIU, Li AI, Yong-Xia LI
2020, 41(12): 123-127. doi: 10.12259/j.issn.2095-610X.S20201235
Abstract(2607) HTML PDF(21) Cited By (3)
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Objective To investigate the correlation between OSA with different severity and coagulation function and sleep respiratory monitoring index by detecting the level of coagulation function in OSA patients with different severity. Methods A total of ...
Association between C-reactive Protein/Albumin Ratio and Long-term Prognosis in Elderly Patients with Heart Failure
Jian-pei SU, Wei-meng TIAN, Jun GU, Mi-yu HE
2020, 41(12): 128-132. doi: 10.12259/j.issn.2095-610X.S20201236
Abstract(5178) HTML PDF(14) Cited By (8)
Abstract:
Objective To investigate the association between the ratio of C-reactive protein to albumin(HS-CRP/Alb)and long-term prognosis in elderly patients with heart failure. Methods A total of 125 aged 65-70 patients with heart failure were enrolled as th...
Efficacy of PCR-reverse Dot Hybridization in Drug Resistance Gene Detection and Drug Sensitivity of BD960 Tuberculosis in Drug Resistance Tuberculosis Detection
Xiao-qin LI, Min ZHOU, Lin WANG, Hai-yan ZENG, Peng-ju LUO, Li-jia LIN
2020, 41(12): 138-141. doi: 10.12259/j.issn.2095-610X.S20201238
Abstract(3506) HTML PDF(17) Cited By (1)
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Objective To analyze the difference between PCR-reverse dot hybridization drug resistance gene detection and BD960 Mycobacterium tuberculosis drug sensitivity test in identifying drug resistance of Mycobacterium tuberculosis, and to discuss its clini...
Review of Correlation between Ischemia-reperfusion Injury and Pyroptosis
Xiao-ying WANG, Zuo-jin LIU, Li-juan SHEN
2020, 41(12): 142-147. doi: 10.12259/j.issn.2095-610X.S20201240
Abstract(3458) HTML PDF(29) Cited By (11)
Abstract:
Ischemia-reperfusion injury is temporary tissue ischemia caused by pathological factors or treatments. After restoring blood flow, it causes tissue damage, which can lead to related organ dysfunction. This injury is closely related to the inflammator...
Advances on the Association between Hashimoto's Thyroiditis and Viral Infection
Fang ZHANG, Xue-juan GAO, Yu CHEN, Yuan FAN, Zu-kun CHEN
2020, 41(12): 148-154. doi: 10.12259/j.issn.2095-610X.S20201241
Abstract(2926) HTML PDF(29) Cited By (20)
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The incidence of Hashimoto Thyroiditis(HT)has been on the rise, especially in young and middle-aged women. Th1 T helper lymphocytes, cytotoxic T lymphocytes, natural killer cells(NK), monocytes, plasma cells are the most important agents involved in ...
Advances in Treatment of Colorectal Neuroendocrine Tumors
Chang-xian CHEN, Li-ju ZHANG, Xiao-ming JIANG, Zhen-yong ZHANG, Wei-jun LIU
2020, 41(12): 155-159. doi: 10.12259/j.issn.2095-610X.S20201242
Abstract(3642) HTML PDF(52) Cited By (2)
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Colorectal neuroendocrine tumors were previously considered to be very rare intestinal tumors. However, with the raising of people's awareness of physical examination and the popularity of colonoscopy, the number of cases detected has been increasing...
Effect Analysis of Situation Simulation Combined with PBL Teaching in Orthopedic Nursing Teaching
Xiao-ping CHEN, Yan GU, Qin-fen LI
2020, 41(12): 164-167. doi: 10.12259/j.issn.2095-610X.S20201244
Abstract(2937) HTML PDF(19) Cited By (17)
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objective To investigate the efficacy of scenario simulation combined with PBL teaching in orthopaedic nursing teaching. Methods From March 2019 to March 2020, 120 nursing students who practiced in the orthopaedic department of The Third people's H...
Family Burden in Elderly Hip Fracture Patients with Cognitive Impairment and Its Influencing Factors
Ge A, Xiao-yan LIU, Li LIU, Yu-jia ZHAN, Ting-ting TANG, Jingnan TAO
2020, 41(12): 168-172. doi: 10.12259/j.issn.2095-610X.S20201246
Abstract(4328) HTML PDF(13) Cited By (5)
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Objective To explore the burden status and influencing factors of family caregivers in elderly patients with hip fracture and cognitive impairment. Methods Using the convenient sampling method and Zarit Caregiver Burden Scale to investigate the fam...
Effects of Pre-sleep Music Therapy on Sleep Quality and Cancer-related Fatigue in Patients with Breast Cancer Undergoing Radiotherapy
Jiang ZHANG, Yan LIU, Wen-hui LI, Xi-juan ZHAO, Zheng-ting CHEN, Qiong-yao GUAN, Jiang WU
2020, 41(12): 173-178. doi: 10.12259/j.issn.2095-610X.S20201248
Abstract(3761) HTML PDF(32) Cited By (26)
Abstract:
Objective To explore the effect of bedtime music therapy on breast cancer patients' sleep quality and cancer-induced fatigue during radiotherapy. Methods Eighty breast cancer patients in a radiotherapy department of a tertiary hospital in Kunming w...