2021 Vol. 42, No. 4

Original Articles Basic of Medicine
A Study on Diffusion Kurtosis Imaging in Acute Epilepsy Rats
Xia-rong GONG, Li-gong BIAN, Yu-hui CHEN, Jing CHEN, Bo WANG, Guo-li BI
2021, 42(4): 28-32. doi: 10.12259/j.issn.2095-610X.S20210405
Abstract(3453) HTML PDF(11)
Abstract:
Objective To investigate brain abnormalities in rats with acute epilepsy by diffusional kurtosis imaging (DKI). Methods MRI were performed on all rats. DKI images were obtained from 13 epilepsy rats and 9 normal controls. Fractional anisotropy (FA)...
Effect and Mechanism of Puerarin on Experimental Autoimmune Encephalomyelitis in Mice
Guo-yi LIU, Qing-qing ZHAO, Yan WU, Shan-shan LI, Lian-mei ZHONG, Jia GENG
2021, 42(4): 1-7. doi: 10.12259/j.issn.2095-610X.S20210401
Abstract(3781) HTML PDF(37) Cited By (2)
Abstract:
Objective To explore the effect and mechanism of Puerarin on experimental autoimmune encephalomyelitis (EAE) in mice. Methods C57BL / 6 mice were randomly divided into control group, EAE group and purearin treated EAE group. From the first day of EAE...
Effect of Gentiana Rigescens Franch on Expression of NF - κ B and CTGF in Lung Tissue of Mice with Pulmonary Fibrosis
Na PI, Qin HE, Yan ZHONG, Xuan JIN, Zhen-dong ZHU, Xuan ZHANG
2021, 42(4): 8-12. doi: 10.12259/j.issn.2095-610X.S20210402
Abstract(4130) HTML PDF(26) Cited By (4)
Abstract:
Objective To study the effect of Gentiana rigescens Franch on the protein expression of NF - κ B and CTGF in lung tissue of mice with pulmonary fibrosis. Methods The model of pulmonary fibrosis in Kunming mice was established by intratracheal instill...
Metabonomics of Scopolamine Intoxication in Rats
Ming YAN, Jian-yun YU, Sheng-jie NIE, Yong-qiang QU, Shang-wen WANG, Rui WANG, Jun-jie SHU, Huan LIU, Shu-hua LI
2021, 42(4): 13-19. doi: 10.12259/j.issn.2095-610X.S20210403
Abstract(3751) HTML PDF(29)
Abstract:
Objective To study the relationship between different metabolites, metabolic pathways and toxicity in scopolamine intoxicated rats. Methods 40 Sprague-Dawley (SD) rats were divided into control group and 3 groups with different doses of drugs. Chroni...
Aqueous Extract of Moringa Oleifera Leaves Alleviate Olanzapine-Induced Metabolic Syndrome in Mice
Xue-fang YANG, Rong XIAO, Shun-shan LIAO, De-hong CAI, Zhi-bi ZHANG, Jian-kun LIU
2021, 42(4): 20-27. doi: 10.12259/j.issn.2095-610X.S20210404
Abstract(2709) HTML PDF(20) Cited By (7)
Abstract:
Objective To explore the protective effect and mechanisms of aqueous extract of Moringa oleifera leaves (EMO) on olanzapine (OLA) induced metabolic disorders in mice. Method 90 female mice were randomly divided into control group, OLA group (3 mg/kg)...
Comparative Study of Prevalence and Influencing Factors of Diabetes Mellitus between Han and Bai Ethnic Groups in Rural Areas of Yunnan Province
Chun-mei ZUO, Lian-ju HE, Lan LIU, Wen-long CUI, Jin-bo LI, Yi MO, Le CAI
2021, 42(4): 33-37. doi: 10.12259/j.issn.2095-610X.S20210406
Abstract(5135) HTML PDF(18) Cited By (6)
Abstract:
Objective To compare prevalence of diabetes and its influencing factors between Han and Bai ethnic groups in rural Yunnan. Methods A total of 5, 003 rural residents aged ≥ 35 years in Fumin County of Kunming city and Jianchuan County of Dali Bai Auto...
Periodontal Status and Its Influencing Factors in Rural Population aged 65-74 in Yunnan Province
Hui DING, Lan YAO
2021, 42(4): 38-43. doi: 10.12259/j.issn.2095-610X.S20210407
Abstract(5853) HTML PDF(12) Cited By (2)
Abstract:
Objective To investigate the periodontal status of rural elderly aged 65 to 74 in Ning’ er and Jianchuan counties of Yunnan Province and to analyze the risk factors of periodontal disease. Methods Gingival bleeding and loss of attachment were recorde...
Analysis of Serum Fat-soluble Vitamin Levels in Infants and Children in Anning City
Yan GAO, Xiang-lei TONG, Hao-ran TANG, Li WU
2021, 42(4): 44-48. doi: 10.12259/j.issn.2095-610X.S20210408
Abstract(4283) HTML PDF(21) Cited By (5)
Abstract:
Objective To investigate the serum fat-soluble vitamins levels in infants and children in Anning City, to provide reference data for reasonable fat-soluble vitamin supplementation. Methods From June 2019 to July 2020, 925 infants and children from Ch...
Clinical Research
Efficacy and Safety of Valsartan Amlodipine Tablets Combined with Alpha-lipoic Acid in the Treatment of Elderly Patients with Type 2 Diabetic Nephropathy Complicated with Hypertension
Jin-hong LI, Hong WANG
2021, 42(4): 53-56. doi: 10.12259/j.issn.2095-610X.S20210410
Abstract(3124) HTML PDF(18) Cited By (29)
Abstract:
Objective To analyze the clinical efficacy and safety of valsartan amlodipine tablets combined with alpha-lipoic acid in the treatment of elderly type 2 diabetic nephropathy complicated with hypertension. Methods A total of 40 elderly patients with...
Comparative Study of Windowing the Femur Diaphysis and Extended Trochanteric Osteotomy in Femoral Revision Surgery
Jun-jie ZHOU, Jin ZHOU, Jia-hui CHENG, Biao LI, YI YANG
2021, 42(4): 96-101. doi: 10.12259/j.issn.2095-610X.S20210418
Abstract(2653) HTML PDF(7) Cited By (1)
Abstract:
Objective To compare windowing the femur diaphysis and extended trochanteric osteotomy for hip implants extraction in revision surgery. Methods We retrospective analyzed data of 18 patients (18 hips) with primary hip arthroplasty undergone windowin...
Comparison of the Efficacy of Ommaya Reservoir and Lumbar Cistern Intervention of Tuberculous Meningoencephalitis Complicated with Hydrocephalus
Guo-ji CHANG, Ying HUANG, Yan-ling ZHANG, Hua HE, Jun XU, Yang LI
2021, 42(4): 122-127. doi: 10.12259/j.issn.2095-610X.S20210423
Abstract(3424) HTML PDF(17) Cited By (3)
Abstract:
Objective To investigate the clinical efficacy of cerebrospinal fluid drainage and injection by Ommaya reservoir implantation and lumbar cistern intervention in the treatment of patients of tuberculous meningoencephalitis with hydrocephalus. Method...
Advantages of 3D-DSA in Neurointervention
Kai HOU, Ying-na GONG, Bin LI, Chong-bin LIU, Hong LIU, Yi LI, Jian-feng ZHONG
2021, 42(4): 128-133. doi: 10.12259/j.issn.2095-610X.S20210424
Abstract(2816) HTML PDF(42) Cited By (4)
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Objective To analyse the diagnostic advantages and therapeutic value of 3D-DSA compared with conventional 2D-DSA in nerointervention in the “Gold Standard”. Methods A total of 277 cases who underwent neurointerventional therapy using 2D and 3D-DSA ...
Correlation between Urinary Iodine and Thyroid Diseases
YAN TANG, Bo-yi LI, Rong MA, Ling NIU, Fang LIU, Cui-juan MIAO
2021, 42(4): 134-137. doi: 10.12259/j.issn.2095-610X.S20210425
Abstract(3101) HTML PDF(14) Cited By (4)
Abstract:
Objective To investigate the correlation between urinary iodine and thyroid diseases. Method A total of 266 patients who received physical check-up or treatment in the Department of Endocrinology of our hospital from January to December 2018 were e...
Changes in Pathogen Composition of Hand-Foot-and-Mouth Disease in Outpatient and Emergency Departments in Kunming Maternal and Child Health Hospital during 2014-2018
Xiu-fang LI, Yan WANG, Chun-ming LIU, Da-chun DAI, Gui-yun YANG
2021, 42(4): 138-141. doi: 10.12259/j.issn.2095-610X.S20210426
Abstract(3519) HTML PDF(9) Cited By (1)
Abstract:
Objective To explore the pathogenic composition of hand-foot-and-mouth disease (HFMD) in outpatient of The Maternal and Child Health Hospital of Kunming from 2014 to 2018, so as to understand the immune protection status of enterovirus 71 (EV71) vacc...
Clinical Study of HIMSS Stage 6 Technology in Preventing Medication Errors in Children
Jian-ming SUN, Qin SU, Kun-xiang WANG, Chun-yan ZHAO, Yuan LI, Quan-hong LI, Ming PU
2021, 42(4): 142-145. doi: 10.12259/j.issn.2095-610X.S20210427
Abstract(4276) HTML PDF(7)
Abstract:
Objective To study the efficacy of HIMSS stage 6 on the number and types of medication order errors. Methods Data of medication order errors after application of HIMSS stage 6 technology were collected as the study group, and data of medication o...
Expression of Long Non-coding RNA APTR,HEIH,FAS-ASA1,FAM83H-AS1,DICER1-AS1,PR-lncRNA in Lung Cancer
Teng-fei ZHANG, Yue-feng HE, Lei ZHANG, Li ZHANG, Kai-yun YANG, Lian-qing LIU, Hui TAN
2021, 42(4): 49-52. doi: 10.12259/j.issn.2095-610X.S20210409
Abstract(3630) HTML PDF(109) Cited By (4)
Abstract:
Objective To investigate the expression of long non-coding RNA (IncRNA) APTR, HEIH, FAS-ASA1, FAM83H-AS1, DICER1-AS1 and PR-lncRNA in lung cancer patients. METHODS Total RNA was extracted by TRI Z O L from cancer tissues, adjacent normal tissues and ...
Analysis of Structural Abnormality of Temporomandibular Joint in 175 Cases before Orthodontic
Li ZHANG, Wan-yuan YUE, Shuang YANG, Shan-yong ZHANG
2021, 42(4): 57-60. doi: 10.12259/j.issn.2095-610X.S20210411
Abstract(4680) HTML PDF(24) Cited By (1)
Abstract:
Objective To investigate the abnormal structure of temporomandibular joint (TMJ) in patients before orthodontic treatment, and to provide guidance for clinical treatment. Methods A total of 175 patients aged 10-40 years before orthodontic treatment i...
Effects of Different Ventilation Modes on PaO2 and Lactic Acid in Arterial Blood of Upper and Lower Limbs in Rectal Cancer Patients under Trendelenburg Posture
Min ZHAO, Hui YANG, Wei-hao MA, Shan-shan LI
2021, 42(4): 61-66. doi: 10.12259/j.issn.2095-610X.S20210412
Abstract(2914) HTML PDF(10)
Abstract:
Objective To investigate the changes of upper and lower limb artery PaO2 and blood lactic acid in rectal cancer patients with different ventilation modes in Trendelenburg position during perioperative period, so as to provide basis and reference for ...
Expression of XB130 in Hepatocellular Carcinoma and Its Effect on Cell Invasion and Migration
Song-xu QI, Cheng QIU, Rong-jun CHEN, Zhan-hui CHEN, Wan-yu ZHANG, Shi-long TANG, Fan CAO, Chun-man LI, Nan XIE
2021, 42(4): 67-72. doi: 10.12259/j.issn.2095-610X.S20210413
Abstract(3860) HTML PDF(11)
Abstract:
Objective To investigate the expression of new adaptor protein XB130 in hepatocellular carcinoma (HCC) tissues and adjacent tissues and its relationship with histopathology, and to explore its influence on the invasion and migration of hepatocellular...
Effect of Plasma Exchange with Double Plasma Molecular Adsorption on Cytokines in Autoimmune Hepatitis with Liver Failure
Wei-sha ZHOU, Le ZHANG, Jing PENG, Shou-kun CHEN, Meng-jun LIU, Xiao FU, Zhi-fei TANG, Yun-xuan YUE
2021, 42(4): 73-77. doi: 10.12259/j.issn.2095-610X.S20210414
Abstract(4399) HTML PDF(19) Cited By (6)
Abstract:
Objective To study the effect of Plasma Exchange (PE) combined with Double Plasma Molecular Absorption System (DPMAS) on cytokines in patients with autoimmune hepatitis complicated with liver failure, and to explore the significance of Plasma Exchang...
Expression of B7-H4 in Intrahepatic Cholangiocarcinoma and Its Clinical Significance
Gang LI, Jin-song LI, Nan XIE, Chun-mang LI, Lei WEI, Fan CAO, Ying-zhen SU
2021, 42(4): 78-83. doi: 10.12259/j.issn.2095-610X.S20210415
Abstract(3995) HTML PDF(14) Cited By (1)
Abstract:
Objective To investigate the expression of costimulatory molecule B7-H4 in intrahepatic cholangiocarcinoma (ICC)and its clinical significance. Methods Immunohistochemistry was used to detect the expression of B7-H4 in 90 cases of intrahepatic cholang...
Effects of Different Concentrations of Magnesium Ions on Endothelial Progenitor Cells in Women with Gestational Diabetes
Yan-shang ZHANG, Li LI, Xin-ling WANG, Su-xin LIU, Guo-juan MA, Yan HUO
2021, 42(4): 84-90. doi: 10.12259/j.issn.2095-610X.S20210416
Abstract(2822) HTML PDF(28)
Abstract:
Objective To explore the effects of different concentrations of magnesium ion intervention on endothelial progenitor cells (endothelial progenitor cells, EPCs) in women with gestational diabetes (gestaional diabetes mellitus, GDM). Methods 204 cases ...
Clinical Characteristics and Serum Levels of Endoplasmic Reticulum Stress Factors HSP47, XBP-1S and GRP78 in Elderly Women with Acute Myocardial Infarction
Ni-ni TIAN, Hong-qing ZHANG, Min TIAN, Cai-ping LV, Bin YANG, Feng XU, Hong-jian LI, Xing-hua PAN
2021, 42(4): 91-95. doi: 10.12259/j.issn.2095-610X.S20210417
Abstract(4172) HTML PDF(18) Cited By (4)
Abstract:
Objective To investigate the clinical characteristics of female patients with myocardial infarction and the differences in serum levels of endoplasmic reticulum stress proteins HSP47, XBP-1S, and GRP78 with male patients. Methods A total of 356 pati...
Efficacy of Double Tract Reconstruction of Proximal Gastrectomy and Radical Total Gastrectomy of Upper Gastric Cancer
Ye YUAN, Jian CHANG, Dong-bo LIU, Bao-cheng JIANG
2021, 42(4): 102-106. doi: 10.12259/j.issn.2095-610X.S20210419
Abstract(2496) HTML PDF(14) Cited By (4)
Abstract:
Objective To study the efficacy of proximal gastrectomy with double tract reconstruction and total radical gastrectomy for upper gastric cancer. Methods 50 patients who underwent radical resection of upper gastric cancer in Suzhou Jiulong Hospital fr...
Clinical Analysis of 87 Cases of Hyporenal Abdominal Iliac Artery Disease Treated with Integrated Bifurcated Stent
Xun-qiang LIU, Chun-xin YANG, Xiao-na ZHOU, Wen-kai JI, Huan-jun CHEN, Jin-hui ZHANG, Li-qiong ZHANG, Cui-hong LI
2021, 42(4): 107-112. doi: 10.12259/j.issn.2095-610X.S20210420
Abstract(3075) HTML PDF(13)
Abstract:
Objective To explore the clinical efficacy of the treatment of subrenal iliac abdominal artery disease with integrated bifurcated stent graft. Methods Retrospective analysis was performed on 87 cases of subrenal abdominal iliac artery disease treated...
Clinical Application of Vectorcardiogram in Diagnosis of Left Ventricular Abnormalities in Hypertension
You-ling LONG, Deng PAN, Tian-zhen XIONG, Yue PAN, Yong SU, Lin XIONG, Yan WU, Ying LI
2021, 42(4): 113-116. doi: 10.12259/j.issn.2095-610X.S20210421
Abstract(4082) HTML PDF(175) Cited By (3)
Abstract:
Objective To evaluate the application value of vectorcardiogram (VCG) in the diagnosis of left ventricular abnormalities in the early stage of hypertension. Methods The electrocardiogram (ECG), VCG and ultrasonic cardiogram (UCG) of 76 patients with ...
Retrospective Analysis of 376 Cases of Adverse Reactions to Antituberculosis Drug
Na LI, Jie CHEN, Ji LUO, Yong-gang CHEN, Jiang-li PENG, Ming-li YU, Sheng-hao LI
2021, 42(4): 117-121. doi: 10.12259/j.issn.2095-610X.S20210422
Abstract(3848) HTML PDF(15) Cited By (16)
Abstract:
Objective To explore the specific types, occurrence time and age structure of adverse reaction (ADR) in tuberculosis patients after anti-tuberculosis treatment, so as to provide certain reference for rational, safe and effective drug use in clinical ...
Reviews
Advances in Application of Ultrasound in Neuropathic Pain
Bin WANG, Ye-hui LIAO, Mo-xuan CHEN, Yao LIU, Yun-xin ZHAO, Li-juan AO
2021, 42(4): 155-160. doi: 10.12259/j.issn.2095-610X.S20210430
Abstract(2652) HTML PDF(34) Cited By (4)
Abstract:
Ultrasound is a non-invasive and safe treatment technique, which has a therapeutic efficacy on most neuropathic pain diseases. Neuropathic pain had been recognized as one of the most difficult pain syndromes in the world. It has a long course and ser...
Advances in Extracellular Polymeric Substances in Biofilm
Jing ZHOU, Li-jun HUO, Ya-yan LEI, Hong-bing HE
2021, 42(4): 150-154. doi: 10.12259/j.issn.2095-610X.S20210429
Abstract(3822) HTML PDF(83) Cited By (6)
Abstract:
Biofilm extracellular polymeric substances are the basic substances produced by microorganisms in the biofilm formation process, which lead to the enhancement of bacterial pathogenicity, playing an important role in change of microbial behavior, viru...
Nursing Forum
Efficacy of Oral Immunotherapy with Colostrum on Preterm Very Low Birth Weight Infants
Ting HU, Da-zhi CHEN, Jin-rong MA, Ping LI, Ze-lan MENG, Chun-hua LEI, Lei ZENG, Ju-ying PU, Fang GUO
2021, 42(4): 172-175. doi: 10.12259/j.issn.2095-610X.S20210433
Abstract(3221) HTML PDF(17) Cited By (5)
Abstract:
Objective To explore the effect of oral immunotherapy of mother’ s colostrum on very low birth weight premature infants. Methods A total of 100 very low birth weight premature infants born in our hospital from June 2018 to June 2020 were enrolled a...
Application of Nursing Health Education Pathways Under ERAS Concept in Perioperative Period of Laparoscopic Liver Lobotomy
Ying ZHANG, Jing GUO, Feng-xia YANG, Yan ZHOU, Yao HUANG, Xiao-feng DENG, Tao FENG, Na MI
2021, 42(4): 168-171. doi: 10.12259/j.issn.2095-610X.S20210432
Abstract(4713) HTML PDF(21) Cited By (21)
Abstract:
Objective Under the concept of ERAS, according to the characteristics of liver cancer disease and perioperative nursing needs, this paper aims to establish the nursing health education during perioperative period of laparoscopic lobotomy and explore ...
The Practice and Evaluation of Day Surgery Overall Nursing Management for Patients with Endoscopic Intestinal Polypectomy
Xiao-rong CHEN, Wei YUAN, Sheng-li GUO, Ting ZHU, Wei-na LIN, Xu XIAO
2021, 42(4): 176-180. doi: 10.12259/j.issn.2095-610X.S20210434
Abstract(3632) HTML PDF(10) Cited By (11)
Abstract:
Objective To explore the feasibility and effectiveness of whole-course nursing management of intestinal polyp operation. Methods A total of 86 cases of intestinal polyp patients who underwent day surgery in our hospital were selected as the experimen...
Forensic Medicine Research
Effect of Acetone in Human Blood on Ethanol Detection Results
Yan-ming REN, Ji-bin XIONG, Chen-fei ZHAO, Chen-xi LI, An-qi GUAN, Zi-qing XU, Kai-bo ZHANG, Rui-lin ZHANG, Shu-hua LI
2021, 42(4): 146-149. doi: 10.12259/j.issn.2095-610X.S20210428
Abstract(3003) HTML PDF(16) Cited By (5)
Abstract:
Objective To study the effect of acetone in blood samples on the qualitative and quantitative results of ethanol. Methods Headspace gas chromatography (double column and double detector) was used to determine ethanol and acetone in blood samples of 6...
Teaching Research
Application of Comprehensive Index Method in Teaching Performance Evaluation of University Teachers
Shun-ding TANG, Ying SONG, Wei CHANG, Lin-xiong WU, Xiao-qing ZHANG
2021, 42(4): 161-167. doi: 10.12259/j.issn.2095-610X.S20210431
Abstract(3515) HTML PDF(7) Cited By (2)
Abstract:
Objective This paper analyzes the evaluation of the teaching performance of university teachers by the comprehensive index method based on the superior order graph method, and provides reference for the future evaluation of the comprehensive teaching...